Influence of HLA-DPB1 mismatch permissive status on relapse and aGVHD. HLA-DPB1 nonpermissive mismatch in GVH direction is associated with relapse protection (A) without increasing the risk of aGVHD (B). SHRs represent the effect of each group on outcomes in comparison with HLA-DPB1 matched group (reference), adjusted for sex, age, HCT-CI, DRI, transplant protocol, conditioning regimen intensity, donor relation, stem cell source, and ABO match.