Overall survival. Kaplan-Meier curves of OS according to (A) hematological response (n = 169), (B) renal response (n = 166), (C) baseline eGFR (n = 169), (D) LCDD with or without associated CN (n = 138). Time to event was calculated from the day of the diagnosis of MIDD (D0). OS proportions at 12, 36, and 60 months were 96%, 88%, 88%, vs 68%, 44%, 33% in patients who achieved VGPR/CR or not, respectively (P = .001), and 98%, 87%, 79% vs 73%, 60%, 50% in patients with or without renal response, respectively (P < .0001)