Figure 4.
Representation of published CTAs and LAAs in CML and hematological benign HLA ligandomes. Representation frequencies of published CTAs in HLA class I (A) and class II (B) ligandomes, as well as published LAAs in HLA class I (C) and class II (D) ligandomes in CML patient and hematological benign samples. Pie charts represent the total amount of identified CTAs and LAAs assigned to their degree of CML association (ie, CML-exclusive, CML-overrepresented, benign-overrepresented, benign-exclusive). Bar diagrams depict the relative representation (%) of the respective antigens on CML and hematological benign samples allocated to their CML association. Only antigens with representation frequencies >5% (A-B,D) or >25% (C) in the respective cohort are shown.