Figure 5.
Immune reconstitution posttransplantation. (A) Absolute numbers of CD3, CD4, CD8+, and CD4/CD45RA/CD62L+ T cells, B cells, and natural killer cells as measured by flow cytometry are shown. Each box extends from the 25th to 75th percentile with a line at the median and whiskers extending 1.5 times the interquartile range. (B) The number of signal joint TRECs, normalized per 1 × 106 CD3 cells, and TCR Vβ repertoire, measured as TCR spectrotype complexity score (TCR SCS), which counts the number of peaks/TCR Vβ subfamily (maximum score, 208); they were measured pretransplantation and posttransplantation to better assess thymic recovery. (C) A representative example of pretransplantation and posttransplantation TCR SCS.