Figure 7.
Effect of cDLI posttransplantation. (A) Nine subjects received cDLI for mixed whole-blood or T-cell chimerism. Improvement in T-cell chimerism was reported in the majority of patients at 120 days after cDLI. (B) Ten subjects received cDLI for viral infection (7 with viremia, 3 with symptomatic viral gastroenteritis). Improvement in viremia and/or clinical symptoms was seen in 6 of 10 subjects. (C) Seven subjects received cDLI for delayed immune reconstitution. Improvement in absolute CD3 count was noted in all 7 subjects. (D) The cumulative incidence of acute GVHD or progression of acute GVHD was 47% (95% CI, 23-69) in subjects who received cDLI and 48% (95% CI, 28-66) in those who did not.