Patterns of FDG uptake in BM. (A) Example of multifocal BM FDG uptake (right humerus, multiple bilateral ribs, and iliac bone) on baseline PET/CT without diffuse FDG uptake, considered positive for BMI (i, maximum intensity projection; ii, coronal fused PET/CT; iii, axial PET; and iv, axial fused PET/CT). (B) Example of multifocal BM FDG uptake (bilateral humeri, femora, and iliac bone) with additional diffuse uptake greater than liver reference on baseline PET/CT, considered positive for BMI (i, maximum intensity projection; ii, sagittal PET; iii, fused PET/CT; iv, axial PET; and v, fused PET/CT). (C) Example of pure diffuse FDG uptake pattern, considered negative for BMI (i, maximum intensity projection; ii, sagittal PET; and iii, sagittal fused PET/CT).