Ampd3 deficiency causes a reduction in mouse naive T cells. (A) Flow cytometry data showing frequencies of various T-cell populations in Ampd3^−/− mice (reported as percentage of parent) (n = 25, n = 32, and n = 10 for Ampd3^+/+, Ampd3^+/−, and Ampd3^−/−, respectively). (B) MFI of CD62L and CD44 of CD4⁺ or CD8⁺ T cells from Ampd3^+/+, Ampd3^+/−, and Ampd3^−/− mice. (C) Representative flow cytometry result showing CD62L and CD44 expression of CD4⁺ or CD8⁺ T cells in Ampd3^−/− and wild-type mice. *P ≤ .05, **P ≤ .01, ***P ≤ .001. Ampd3^+/+ vs Ampd3^−/−. cMem, central memory T cells; eMem, effector memory T cells; ns, not significant (P > .05).