Figure 3.
Ampd3-deficient mice show normal complete blood counts and normal T-dependent antibody response to rSFV-β-Gal but an attenuated response to OVA. (A) Complete blood count was obtained using a Hemavet 950. T cell-dependent IgG antibody was measured 14 days after immunization by rSFV-β-Gal (B) or OVA-alum (C) at 2 serum dilutions (1:50 and 1:150). (D) Killing efficacy of OVA peptide–labeled B6 splenocytes by host cytotoxic T lymphocytes (CTL). **P ≤ .01. BA, basophils; EO, eosinophils; HB, hemoglobin; LY, lymphocytes; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; MO, monocytes; MPV, mean platelet volume; NE, neutrophils; ns, not significant (P > .05); O.D., optical density; PLT, platelet; RBC, red blood cell; WBC, white blood cell.

Ampd3-deficient mice show normal complete blood counts and normal T-dependent antibody response to rSFV-β-Gal but an attenuated response to OVA. (A) Complete blood count was obtained using a Hemavet 950. T cell-dependent IgG antibody was measured 14 days after immunization by rSFV-β-Gal (B) or OVA-alum (C) at 2 serum dilutions (1:50 and 1:150). (D) Killing efficacy of OVA peptide–labeled B6 splenocytes by host cytotoxic T lymphocytes (CTL). **P ≤ .01. BA, basophils; EO, eosinophils; HB, hemoglobin; LY, lymphocytes; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; MO, monocytes; MPV, mean platelet volume; NE, neutrophils; ns, not significant (P > .05); O.D., optical density; PLT, platelet; RBC, red blood cell; WBC, white blood cell.

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