Reduction in Ampd3^−/− naive T cells is restricted to peripheral blood. (A) Percentages of naive CD4⁺ T cells and naive CD8⁺ T cells in blood, lymph node (LN), and spleen (n = 3 and n = 4 for Ampd3^+/+ and Ampd3^−/−, respectively). (B) Representative flow cytometry analysis of CD62L and CD44 expression of CD4⁺ T cells from different tissues. ***P ≤ .001. ns, not significant (P < .05).