Figure 4.
Survival analysis of DLBCL according to the studied markers. (A) Forest plots of univariate Cox regression analyze showing hazard ratios with 95% confidence intervals for overall survival according to studied alterations in the whole study cohort and separately among the immunohistochemically defined GCB and non-GCB DLBCLs. For RNAseq-based analyses, see supplemental Figure 4A-B. Red dots indicate FDR <10% for all P values listed in panel A. (B-E) Kaplan-Meier estimates of highlighted survival associations and respective multivariate models. (B) Double protein expression among the whole cohort. (C) Double alterations among the GCB DLBCLs. BCL2GA (D) and BCL6TL (E) among the non-GCB DLBCLs.