Summary of response rates and MRD-negativity (10⁻⁵) rates over time. (A) Response rates over time are shown. Data for the end of induction, end of ASCT, and end of consolidation are from the primary analysis. Response data with longer median follow-up of 22.1 months are also shown (last follow-up). (B) MRD-negativity (10⁻⁵) rates in the intent-to-treat population by the end of induction therapy, end of consolidation, and last follow-up. All MRD data are from the analysis with a median follow-up of 22.1 months. MRD was evaluated at baseline, first evidence of suspected CR or sCR, at the end of induction and consolidation, and after 12 and 24 months of maintenance, regardless of response (per protocol amendment 2).