Figure 1.
Study outcomes and practice patterns. (A) PFS and OS for the whole cohort of patients with Ph+ ALL. (B) PFS and OS for patients with Ph+ ALL who underwent allo-HCT while in CR1. (C) Dot matrix chart showing percentage of patients receiving different types of TKI. (D) Landmark analysis of patients who were in CMR status before and at 3 months after allo-HCT, with a significantly higher PFS in patients who received prophylactic TKI therapy compared with those who did not. (E) Graph showing increased incidence of relapse in patients who discontinued TKI therapy before 24 months vs those who continued for >24 months. (F) Decreasing percentage of patients who underwent transplantation while in CR1 over time.