Regulation of Hepcidin Production by the Liver. Three major processes that influence hepcidin transcription are 1) induction by infection/inflammation (green), 2) induction by iron status (blue), or 3) suppression by expanded erythroid precursors (red). Modified slightly from Ganz T, Systemic Iron Homeostasis, Physiol Rev. 2013;93:1721-1741.

Regulation of Hepcidin Production by the Liver. Three major processes that influence hepcidin transcription are 1) induction by infection/inflammation (green), 2) induction by iron status (blue), or 3) suppression by expanded erythroid precursors (red). Modified slightly from Ganz T, Systemic Iron Homeostasis, Physiol Rev. 2013;93:1721-1741.

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