Patient Outcomes Stratified by Canonical Mutation and Number Of Somatic Alterations. (a) Overall survival based on canonical mutation. Individual canonical driver mutations were not associated with outcome (logrank p = 0.834). (b) Overall survival rates according to the number of somatic alterations at diagnosis. Adapted by permission from Macmillan Publishers Ltd: Nat Genet Volume 47 Pages 1326-1333, copyright 2015.