Protocol Schematics. a) Schematic of CD45-SAP conditioning protocol. Mice were treated with 3 mg/kg CD45-SAP and transplanted with 107 bone marrow cells two to 12 days later. b) Long-term assessment of peripheral blood chimerism after transplantation eight days following CD45-SAP conditioning. c) Schematic of combination ACK2 and CV1mb conditioning protocol. Mice were treated once with 500 μg ACK2 and 500 μg CV1mb for five days. A day later, 1 million lineage-depleted bone marrow cells were transplanted. d) Frequency of donor-derived hematopoietic stem cells 24 weeks after transplantation.

Protocol Schematics. a) Schematic of CD45-SAP conditioning protocol. Mice were treated with 3 mg/kg CD45-SAP and transplanted with 107 bone marrow cells two to 12 days later. b) Long-term assessment of peripheral blood chimerism after transplantation eight days following CD45-SAP conditioning. c) Schematic of combination ACK2 and CV1mb conditioning protocol. Mice were treated once with 500 μg ACK2 and 500 μg CV1mb for five days. A day later, 1 million lineage-depleted bone marrow cells were transplanted. d) Frequency of donor-derived hematopoietic stem cells 24 weeks after transplantation.

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