"One-Year NRM for Patients Classified by Number of Risk Factors at GVHD Onset. Clinical stage (high risk = stage 2-4), histologic grade (high risk = grade 4), and Reg3α concentration (high risk > 151 ng/mL); 0 (purple, NRM = 25%); 1 (red, NRM= 34%); 2 (blue, NRM = 66%); 3 (brown, NRM = 86%); 0 vs. 1, P = 0.2; 1 vs. 2, P < 0.001; 2 vs. 3, P < 0.001.