Significantly mutated genes/CNA and pathways. (A) Oncoprint representation of the 43 driver alterations identified in MCL. Drivers are depicted in rows, and cases are displayed in columns. Novel driver alterations identified in this study are highlighted in dark orange. (B) Distribution and type of driver alterations in the 2 different MCL subtypes. Drivers with a different proportion of altered cases between subtypes (Q < 0.15) are indicated.