Identification of 330 CODEGs across cytogenetic subgroups. (A) Schematic Venn diagram highlighting the CODEGs. (B) Heat map showing the expression levels of CODEGs in AML and normal BM samples. Centered gene expression is represented in a blue (low expression) to red (high expression) color gradient. Hierarchical clustering of samples was performed using Euclidean distance as a dissimilarity measure and average linkage, and that of genes was performed with Pearson correlation and average linkage. (C) Principal component analysis of samples based on the expression profile of the 330 commonly deregulated genes. Colors represent karyotypes, with red for control samples. (D) Empirical cumulative distribution (ECDF) for the expression of the 330 commonly deregulated genes across AML subgroups. Red points indicate the maximum distance between expression in the control and AML samples. The Kolmogorov-Smirnov goodness-of-fit test was used to test the similarity of distribution between control and AML samples.