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Author notes
Funding: This work was supported by award HL140025 the National Heart, Lung, and Blood Institute of the National Institutes of Health, and by the Ernest W. Goodpasture Chair in Experimental Pathology for Translational Research from Vanderbilt University.
Disclosures: None of the authors have conflicts of interest related to this manuscript. Unrelated, D.G. is a consultant for several pharmaceutical companies with interests in developing drugs that target factor XI and prekallikrein.
Data Sharing Statement: All new data generated are available in the article.
© 2025 American Society of Hematology. Published by Elsevier Inc. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution. All other rights reserved.
2025