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Journal Articles

Lymphoid blast transformation in an MPN with BCR-JAK2 treated with ruxolitinib: putative mechanisms of resistance

Clinical Trials & Observations
Justin Anthony Chen, Yanli Hou, Krishna M. Roskin, Daniel A. Arber, Charles D. Bangs, Linda B. Baughn, Athena M. Cherry, Mark D. Ewalt, Andrew Z. Fire, Laure Fresard, Hutton M. Kearney, Stephen B. Montgomery, Robert S. Ohgami, Kathryn E. Pearce, Beth A. Pitel, Jason D. Merker, Jason Gotlib
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3492–3496.
https://doi.org/10.1182/bloodadvances.2020004174
Published: 2021
Includes: Supplemental data
Journal Articles

Benign and malignant hematologic manifestations in patients with VEXAS syndrome due to somatic mutations in UBA1

Clinical Trials & Observations
Ifeyinwa Emmanuela Obiorah, Bhavisha A. Patel, Emma M. Groarke, Weixin Wang, Megan Trick, Amanda K. Ombrello, Marcela A. Ferrada, Zhijie Wu, Fernanda Gutierrez-Rodrigues, Jennifer Lotter, Lorena Wilson, Patrycja Hoffmann, Daniela Ospina Cardona, Nisha Patel, Alina Dulau-Florea, Daniel L. Kastner, Peter C. Grayson, David B. Beck, Neal S. Young, Katherine R. Calvo
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3203–3215.
https://doi.org/10.1182/bloodadvances.2021004976
Published: 2021
Includes: Supplemental data
Journal Articles

Prognostic impact of posttransplant FDG PET/CT scan in multiple myeloma

Clinical Trials & Observations
Marcella Kaddoura, David Dingli, Francis K. Buadi, Martha Q. Lacy, Morie A. Gertz, Angela Dispenzieri, Prashant Kapoor, Lisa Hwa, Amie Fonder, Miriam Hobbs, Suzanne Hayman, John Lust, Nelson Leung, Ronald S. Go, Yi Lin, Wilson Gonsalves, Taxiarchis Kourelis, Rahma Warsame, Robert A. Kyle, Stephen M. Broski, Vincent Rajkumar, Shaji Kumar
Journal: Blood Advances
Blood Adv (2021) 5 (13): 2753–2759.
https://doi.org/10.1182/bloodadvances.2020004131
Published: 2021
Journal Articles

G9a/GLP targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor–mediated cell death

Eva De Smedt, Julie Devin, Catharina Muylaert, Nicolas Robert, Guilhem Requirand, Philip Vlummens, Laure Vincent, Guillaume Cartron, Ken Maes, Jerome Moreaux, Elke De Bruyne
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2325–2338.
https://doi.org/10.1182/bloodadvances.2020003217
Published: 2021
Includes: Supplemental data
Journal Articles

Early progression of disease in follicular lymphoma is a robust correlate but not a surrogate for overall survival

Clinical Trials & Observations
Emmanuel Bachy, James R. Cerhan, Gilles Salles
Journal: Blood Advances
Blood Adv (2021) 5 (6): 1729–1732.
https://doi.org/10.1182/bloodadvances.2020003797
Published: 2021
Includes: Supplemental data
Journal Articles

Additional chromosomal abnormalities at chronic myeloid leukemia diagnosis predict an increased risk of progression

Clinical Trials & Observations
Richard E. Clark, Jane F. Apperley, Mhairi Copland, Silvia Cicconi
Journal: Blood Advances
Blood Adv (2021) 5 (4): 1102–1109.
https://doi.org/10.1182/bloodadvances.2020003570
Published: 2021
Includes: Supplemental data
Journal Articles

Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets

Svea Stratmann, Sara A. Yones, Markus Mayrhofer, Nina Norgren, Aron Skaftason, Jitong Sun, Karolina Smolinska, Jan Komorowski, Morten Krogh Herlin, Christer Sundström, Anna Eriksson, Martin Höglund, Josefine Palle, Jonas Abrahamsson, Kirsi Jahnukainen, Monica Cheng Munthe-Kaas, Bernward Zeller, Katja Pokrovskaja Tamm, Lucia Cavelier, Linda Holmfeldt
Journal: Blood Advances
Blood Adv (2021) 5 (3): 900–912.
https://doi.org/10.1182/bloodadvances.2020003709
Published: 2021
Includes: Supplemental data
Journal Articles

Nonmyeloablative allogeneic transplantation achieves clinical and molecular remission in cutaneous T-cell lymphoma

Clinical Trials & Observations
Wen-Kai Weng, Sally Arai, Andrew Rezvani, Laura Johnston, Robert Lowsky, David Miklos, Judith Shizuru, Lori Muffly, Everett Meyer, Robert S. Negrin, Erica Wang, Timothy Almazan, Lynn Million, Michael Khodadoust, Shufeng Li, Richard T. Hoppe, Youn H. Kim
Journal: Blood Advances
Blood Adv (2020) 4 (18): 4474–4482.
https://doi.org/10.1182/bloodadvances.2020001627
Published: 2020
Journal Articles

Genetic mutations and features of mantle cell lymphoma: a systematic review and meta-analysis

Holly A. Hill, Xinyue Qi, Preetesh Jain, Krystle Nomie, Yucai Wang, Shouhao Zhou, Michael L. Wang
Journal: Blood Advances
Blood Adv (2020) 4 (13): 2927–2938.
https://doi.org/10.1182/bloodadvances.2019001350
Published: 2020
Includes: Supplemental data
Journal Articles

Hurdles in treating Hurler disease: potential routes to achieve a “real” cure

Brigitte T. A. van den Broek, Jaap van Doorn, Charlotte V. Hegeman, Stefan Nierkens, Caroline A. Lindemans, Nanda Verhoeven-Duif, Jaap Jan Boelens, Peter M. van Hasselt
Journal: Blood Advances
Blood Adv (2020) 4 (12): 2837–2849.
https://doi.org/10.1182/bloodadvances.2020001708
Published: 2020
Journal Articles

Sex determines the presentation and outcomes in MPN and is related to sex-specific differences in the mutational burden

Clinical Trials & Observations
Theodoros Karantanos, Shruti Chaturvedi, Evan M. Braunstein, Jerry Spivak, Linda Resar, Styliani Karanika, Donna M. Williams, Ophelia Rogers, Christopher D. Gocke, Alison R. Moliterno
Journal: Blood Advances
Blood Adv (2020) 4 (12): 2567–2576.
https://doi.org/10.1182/bloodadvances.2019001407
Published: 2020
Includes: Supplemental data
Journal Articles

Branched evolution and genomic intratumor heterogeneity in the pathogenesis of cutaneous T-cell lymphoma

Aishwarya Iyer, Dylan Hennessey, Sandra O’Keefe, Jordan Patterson, Weiwei Wang, Gane Ka-Shu Wong, Robert Gniadecki
Journal: Blood Advances
Blood Adv (2020) 4 (11): 2489–2500.
https://doi.org/10.1182/bloodadvances.2020001441
Published: 2020
Includes: Supplemental data
Journal Articles

Measurement of ex vivo resistance to proteasome inhibitors, IMiDs, and daratumumab during multiple myeloma progression

Clinical Trials & Observations
Zachary J. Walker, Michael J. VanWyngarden, Brett M. Stevens, Diana Abbott, Andrew Hammes, Christophe Langouët-Astrie, Clayton A. Smith, Brent E. Palmer, Peter A. Forsberg, Tomer M. Mark, Craig T. Jordan, Daniel W. Sherbenou
Journal: Blood Advances
Blood Adv (2020) 4 (8): 1628–1639.
https://doi.org/10.1182/bloodadvances.2019000122
Published: 2020
Includes: Supplemental data
Journal Articles

Integrative analysis of the genomic and transcriptomic landscape of double-refractory multiple myeloma

Bachisio Ziccheddu, Giulia Biancon, Filippo Bagnoli, Chiara De Philippis, Francesco Maura, Even H. Rustad, Matteo Dugo, Andrea Devecchi, Loris De Cecco, Marialuisa Sensi, Carolina Terragna, Marina Martello, Tina Bagratuni, Efstathios Kastritis, Meletios A. Dimopoulos, Michele Cavo, Cristiana Carniti, Vittorio Montefusco, Paolo Corradini, Niccolo Bolli
Journal: Blood Advances
Blood Adv (2020) 4 (5): 830–844.
https://doi.org/10.1182/bloodadvances.2019000779
Published: 2020
Includes: Supplemental data
Journal Articles

Clonal dynamics in chronic lymphocytic leukemia

Catherine Gutierrez, Catherine J. Wu
Journal: Blood Advances
Blood Adv (2019) 3 (22): 3759–3769.
https://doi.org/10.1182/bloodadvances.2019000367
Published: 2019
Journal Articles

Risk of disease transformation and second primary solid tumors in patients with myeloproliferative neoplasms

Junshik Hong, Ju Hyun Lee, Ja Min Byun, Ji Yun Lee, Youngil Koh, Dong-Yeop Shin, Jeong-Ok Lee, Sang Mee Hwang, Hyoung Soo Choi, Inho Kim, Sung-Soo Yoon, Soo-Mee Bang
Journal: Blood Advances
Blood Adv (2019) 3 (22): 3700–3708.
https://doi.org/10.1182/bloodadvances.2019000655
Published: 2019
Includes: Supplemental data
Journal Articles

Low-dose radiation (4 Gy) with/without concurrent chemotherapy is highly effective for relapsed, refractory mantle cell lymphoma

Clinical Trials & Observations
Matthew S. Ning, Chelsea C. Pinnix, Bhavana V. Chapman, Jillian R. Gunther, Sarah A. Milgrom, Joseph D. Khoury, Preetesh Jain, Wendy Y. Chen, Onyeka N. Oriabure, Maria R. Badillo, L. Michael Wang, Bouthaina S. Dabaja
Journal: Blood Advances
Blood Adv (2019) 3 (13): 2035–2039.
https://doi.org/10.1182/bloodadvances.2019030858
Published: 2019
Journal Articles

STAT3β is a tumor suppressor in acute myeloid leukemia

Petra Aigner, Tatsuaki Mizutani, Jaqueline Horvath, Thomas Eder, Stefan Heber, Karin Lind, Valentin Just, Herwig P. Moll, Assa Yeroslaviz, Michael J. M. Fischer, Lukas Kenner, Balázs Győrffy, Heinz Sill, Florian Grebien, Richard Moriggl, Emilio Casanova, Dagmar Stoiber
Journal: Blood Advances
Blood Adv (2019) 3 (13): 1989–2002.
https://doi.org/10.1182/bloodadvances.2018026385
Published: 2019
Includes: Supplemental data
Journal Articles

Impact of acquired del(17p) in multiple myeloma

Clinical Trials & Observations
Arjun Lakshman, Utkarsh Painuly, S. Vincent Rajkumar, Rhett P. Ketterling, Prashant Kapoor, Patricia T. Greipp, Angela Dispenzieri, Morie A. Gertz, Francis K. Buadi, Martha Q. Lacy, David Dingli, Amie L. Fonder, Suzanne R. Hayman, Miriam A. Hobbs, Wilson I. Gonsalves, Yi Lisa Hwa, Nelson Leung, Ronald S. Go, Yi Lin, Taxiarchis V. Kourelis, Rahma Warsame, John A. Lust, Stephen J. Russell, Steven R. Zeldenrust, Robert A. Kyle, Shaji K. Kumar
Journal: Blood Advances
Blood Adv (2019) 3 (13): 1930–1938.
https://doi.org/10.1182/bloodadvances.2018028530
Published: 2019
Includes: Supplemental data
Journal Articles

Metabolomic and molecular insights into sickle cell disease and innovative therapies

Morayo G. Adebiyi, Jeanne M. Manalo, Yang Xia
Journal: Blood Advances
Blood Adv (2019) 3 (8): 1347–1355.
https://doi.org/10.1182/bloodadvances.2018030619
Published: 2019