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First Edition

Letter June 20 2025
Serum TARC: a biomarker for early detection or exclusion of relapse in classic Hodgkin Lymphoma
Sophie A. Teesink,Lydia Visser,Marcel Nijland,Kylie Keijzer,Anne GH Niezink,Bart-Jan Kroesen,Anke van den Berg,Arjan Diepstra,Wouter J Plattel
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Research Article June 20 2025
Allogeneic haematopoietic stem cell transplantation for STAT3 hyper-IgE syndrome: a worldwide study
Christo Tsilifis,Johannes Raedler,Joanna Renke,Michael Medinger,Alexandra Laberko,Ásgeir Haraldsson,Niraj Patel,Peter Ciznar,Melanie Wong,Steven John Keogh, MBBS, FRACP,Paul E Gray,Richard Mitchell,Venetia Bigley,Suzanne Elizabeth Elcombe,Fabian Hauck,Michael H Albert,Eleni Tholouli,Archana Herwadkar,Shuayb Elkhalifa,Chris Kosmidis,Giorgio Callisti,Lauri M. Burroughs,Karin Chen,Ben Carpenter,Thomas A Fox,Emma C. Morris,Ramya Uppuluri,Revathi Raj,Masakatsu Yanagimachi,Emilie Pauline Buddingh,Christina Oikonomopoulou,Corina E Gonzalez,Dimana Dimitrova,Jennifer A. Kanakry,Danielle E Arnold,Sung-Yun Pai,Mary A Slatter,Mark S. Pearce,Austen J Worth,Alexandra F Freeman,Andrew R Gennery
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Research Article June 20 2025
T-cell dysregulation informs radiotherapy-immunotherapy response in B-cell lymphoma: results from a Phase I trial.
Eliza A Hawkes,Jodie Palmer,Richard Khor,Sze Ting Lee,Melinda Burgess,Soi C Law,Maher K. Gandhi,Geoffrey Chong,Jake Shortt,Rakin Chowdhury,Fiona Swain,Leonid Churilov,Michael M MacManus,Charmaine Smith,Fiona Elizabeth Scott,Arina Martynchyk,Allison Barraclough,Kate Manos,Andrew M Scott,Colm Keane
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Letter June 20 2025
One for the ages
Christian Brieghel,Emelie Curovic Rotbain,Jelena Jelicic,Sigrún Thorsteinsdóttir,Peter de Nully Brown,Carsten Utoft Niemann
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Letter June 20 2025
Comments and concerns on the analysis of DAPS-ITP trial
Aarti Hasmukhbhai Vibhakar,Shaan D Shah,Ashwin P Patel
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Research Article June 17 2025
Severe Parvovirus B19 Infection in Patients with Sickle Cell Disease Hospitalized in Intensive Care Unit
Segolene Gendreau,Louis-Marie Coupry,Pierre Cappy,Alexandra Beurton,Nicolas Verger,Anoosha Habibi,Maïté Agbakou,Sylvain Le Jeune,Laurent Argaud,Serge Barmo,Gauthier Blonz,Pierre Cougoul,Stéphanie Houcke,Antoine Lafarge,Arnaud Ly,Andréa Pastissier,Armand Mekontso Dessap,Slim Fourati,Nicolas de Prost
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Research Article June 17 2025
Real-world Evidence of Duvelisib and Romidepsin in Relapsed/Refractory Peripheral and Cutaneous T-cell Lymphomas
Josie Ford,Min Jung Koh,Alexandra W. Lenart,Caroline T MacVicar,Kusha Chopra,Arushi Meharwal,Mark N Sorial,Mwanasha H Merrill,Anna Baird Rider,Aliyah Sohani,Sean Michael McCabe,Ronald A Nemec,Makoto Iwasaki,Dhruv Mistry,Khyati Maulik Kariya,Steven Chen,Jeffrey A. Barnes,Steven McAfee,Yi-Bin Chen,Corben Yuwai Wong,Kristiana Nasto,Eric D. Jacobsen,Salvia Jain
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Research Article June 17 2025
IGSF9-targeted therapy inhibits the progression of acute myeloid leukemia
Lijun Hui,Jing Xiao,Zhiling Zhao,Juan Zhang,Huiwen Luan,Jiashen Zhang,Yuxiao Sun,Xianhui Meng,Hongying Wang,Chunling Li,Fangmin Li,Shuhao Ji,Shuping Wei,Fang Li,Hong Yu,Chengyun Zheng,Yang Jiang,Yaopeng Wang,Zunling Li
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Research Article June 17 2025
Pralatrexate Is Effective in Cytotoxic Cutaneous T-cell Lymphomas
Christina Poh,Jenna M Voutsinas,Mazyar Shadman,Ryan C. Lynch,Edus H Warren,Caitlin A Crimp,Brian G Till,Chaitra S. Ujjani,Mengyang Di,Vikram Raghunathan,Stephen D Smith,Qian Vicky Wu,Michi M. Shinohara,Ajay K Gopal
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Review Article June 15 2025
Cortisol in Sickle Cell Disease: A Systematic Review and Meta-Analysis
Kemar V. Prussien,Margaret Mary Burke,Kandace Gollomp,Rosalind J Wright,Alexis A. Thompson
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Research Article June 15 2025
Outcomes of Haploidentical vs Mismatched Unrelated Donor HCT with Post-Transplant Cyclophosphamide Prophylaxis
Yosra M. Aljawai,Jeremy L. Ramdial,Gabriela Rondon,Portia Smallbone,Partow Kebriaei,Uday R. Popat,Betul Oran,Katayoun Rezvani,Richard E. Champlin,Elizabeth J. Shpall,Rohtesh S. Mehta
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Research Article June 15 2025
A Phase 2 Study of Obinutuzumab Combined with Lenalidomide in Previously Untreated High Tumor Burden Follicular Lymphoma
Neha Akkad,Lei Feng,Jason R Westin,Fredrick B. Hagemeister,Hun Ju Lee,Luis E. Fayad,Sairah Ahmed,Ranjit Nair,Maria Alma Rodriguez,Paolo Strati,Dai Chihara,Christopher R. Flowers,Linda Claret,Karina Liseth Ibanez,Michael L Wang,Nathan H Fowler,Jared Henderson,Richard Eric Davis,Sattva S. Neelapu,Michael R Green,Loretta Nastoupil
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Letter June 15 2025
Peripheral Neuropathy and BTKis in Waldenström: A Response?
Chiara Briani,Bruno Ferrero,Alessandro Salvalaggio,Simone Ragaini,Enrico Amaducci,Irene Dogliotti,Andrea Visentin,Simone Ferrero
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Research Article June 12 2025
BRCA1/2 impact on the development of implant-associated lymphoma in women with breast cancer and textured implants
Paola Ghione,Diana Mandelker,Maria E. Arcila,Venkatraman E Seshan,Mary Beth Terry,Vijai Joseph,Peter Gabriel Cordeiro,Chad Vanderbilt,Joyce C. Pressley,Alexander Chan,Natasha Galasso,Ahmet Dogan,Gilles A. Salles,Daphne de Jong,Flora E. van Leeuwen,Steven M Horwitz
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Research Article June 12 2025
Bone marrow and blood demonstrate distinct immune reconstitution patterns and correlations with relapse post-transplant
Susan DeWolf,Jason Kuttiyara,Paola Vinci,Teng Fei,John Slingerland,Zoe A Katsamakis,Joshua A Fein,Brianna Gipson,Rachel Lorenc,Victoria Zinsmeyer,LeeAnn Marcello,Paul Giardina,William Donohoe,Gunjan L Shah,Richard J. Lin,Esperanza B. Papadopoulos,Boglarka Gyurkocza,Brian C. Shaffer,Martin S. Tallman,Ioannis Politikos,Sergio A. Giralt,Juliet Barker,Miguel-Angel Perales,Roni Tamari,Omar Abdel-Wahab,Christina Cho,Katharine Hsu,Jonathan U. Peled,Marcel R.M. van den Brink,Alan M. Hanash
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Research Article June 12 2025
Safety and Efficacy of Apixaban Thrombosis Prevention in the Obese Pediatric Patients with Acute Lymphoblastic Leukemia
Vilmarie Rodriguez,Sarah H. O'Brien,Etan Orgel,Corinna L. Schultz,Adam J Esbenshade,Arteid Memaj,Joshua L. Dyme,Nicholas A. Favatella,Lesley G Mitchell
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Research Article June 12 2025
Familial Forms of Chronic Lymphocytic Leukemia Have a Worse Prognosis Than Sporadic Forms: an Italian Case-Control Study
Alberto Fresa,Idanna Innocenti,Annamaria Tomasso,Candida Vitale,Alessandro Sanna,Anna Maria Frustaci,Andrea Visentin,Azzurra Romeo,Paolo Sportoletti,Annamaria Giordano,Francesca Perutelli,Roberta Murru,Francesca Romana Mauro, Hematology, Hematology, Department of Translational and Precision Medicine,Antonio Mosca,Francesca Morelli,Roberta Laureana,Andrea Galitzia,Ilaria Angeletti,Esmeralda Conte,Riccardo Moia,Giovanni D'Arena,Raffaella Pasquale,Francesco Autore,Jacopo Olivieri,Luca Stirparo,Giulia Benintende,Francesco Angotzi,Florenzia Vuono,Andrea Corbingi,Maria Ilaria Del Principe,Diana Giannarelli,Alessandra Tedeschi,Marta Coscia,Eugenio Sangiorgi,Dimitar G Efremov,Luca Laurenti
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Research Article June 10 2025
Expression of HERV-K and embryonic genes in chronic lymphocytic leukemia and their association with therapy regimens
Claudia Matteucci,Vita Petrone,Alessandro Giovinazzo,Roberta Laureana,Massimiliano Postorino,Livio Pupo,Chiara Cipriani,Nicola Toschi,Marialaura Fanelli,Antonella Minutolo,Giovangiacinto Paterno,Elisa Buzzatti,Paola Sinibaldi Vallebona,Antonella Zucchetto,Federico Pozzo,Valter Gattei,Giovanni Del Poeta,Adriano Venditti,Emanuela Balestrieri,Maria Ilaria Del Principe
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Research Article June 10 2025
Extramedullary plasmacytoma in children is a genetically distinct localized neoplasia curable by surgical resection
Ilske Oschlies,Julia Richter,Amelie Alfert,Fernando Chahud,Stephanie Mueller,Ingrid Simonitsch-Klupp,Hannah von Mersi,Andishe Attarbaschi,Karoline Koch,Christoph Schaefers,Monika Brüggemann,Cecilia Bozzetti,Wilhelm Woessmann,Birgit Burkhardt,Wolfram Klapper
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Review Article June 9 2025
Blinatumomab Use in Pediatric B-ALL: Where are we now?
Anurekha G Hall,Rachel E Rau
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Research Article June 9 2025
Thyroid hormones contribute to JAK/STAT pathway abnormal activation promoting T-cell lymphoma dissemination
María Mercedes Debernardi,Alejandro Correa,Lucero Alvarado,María V. Revuelta,Helena Andrea Sterle,Gonzalo Gonzalez,Ingrid Larissa Melo Souza,Jorgelina Nelly Real, Dra,María Teresa Garcia de Dávila,Johanna Abigail Diaz Albuja,Cinthia Rosemblit,Leandro Cerchietti,Graciela A Cremaschi,Florencia Cayrol
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Research Article June 9 2025
Prebiotic fibre enteral supplementation post allogeneic transplantation; feasibility and impact on the microbiome
Sarah Andersen, PhD, Adv APD,Glen A Kennedy,Merrilyn Banks,Bernadine Mary Flanagan, BSc (Hons) PhD,Andrea S Henden
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Research Article June 5 2025
Indirect comparison of epcoritamab vs chemoimmunotherapy, mosunetuzumab, or odronextamab in follicular lymphoma
Alexey V Danilov,Swetha Thiruvengadam,Kim Linton,Karen Cumings,Viktor V Chirikov,Alex Mutebi,Savreet Bains Chawla,Anindit Chhibber,Fernando Rivas Navarro,Felipe Marques Gonçalves,Anthony Wang,Zhijie Ding,Abualbishr Alshreef,Elena Favaro,Daniela Hoehn,Anna Sureda
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Letter June 5 2025
Adult thymectomy is associated with increased mortality risk from cancer but not cardiovascular disease
Kameron Allen Kooshesh,Brody Harry Foy,Richard A Baylis,Karin Gustafsson,Daniel A Zlotoff,Tomas G Neilan,David T Scadden
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Review Article June 5 2025
To Pursue Gene Therapy or Not? Is ItFeasible After Graft Failure in Allogeneic Hematopoietic Cell Transplant Recipients
Akshay Sharma,Tami D. John
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Letter June 5 2025
The efficacy of rosuvastatin to reduce circulating tissue factor extracellular vesicles after ovarian cancer surgery
Soravis Osataphan,Rushad Patell,Mrigya Babuta,Rachel P Rosovsky,Yohei Hisada,Charly Edmiston,Pavania Elavalakanar,Michael A Pfeffer,Amy Bregar,Amanda Ramos,Leslie Garrett,Siyang Ren,Donna S. Neuberg,Gyongyi Szabo, Prof.,Robert Flaumenhaft,Nigel Mackman,Meghan Shea,Jeffrey I. Zwicker
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Research Article June 5 2025
Uncovering the Role of the Hsp40 Family Member, Cysteine String Protein-α, in Mouse Platelets
Alexis N. Smith,Hammodah R Alfar,Smita Joshi,Daniëlle Marije Coenen,Joshua T. Lykins,Isabelle C Becker,Brittany E Dong,Harry Chanzu,Chi Peng,Kanakanagavalli Shravani Prakhya,Linda Adannia Nneka Omali,Irina D. Pokrovskaya,Brian Storrie,Joseph E Italiano, Jr,Sidney Wally Whiteheart
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Research Article June 5 2025
National Alliance of Sickle Cell Centers Consensus Standards for Transition to Adult Care in Sickle Cell Disease
Stephanie Guarino,Akshat Jain,Mohan Madisetti,Kenneth A Rivlin,Payal Chandarana Desai,Julie Kanter,Sophie Lanzkron,Deepa G Manwani
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Research Article June 5 2025
Elucidating the dynamics of Integrin αIIbβ3 from native platelet membranes by cryo-EM with build and retrieve method
Xu Han,Zhemin Zhang,Chih-Chia Su,Meinan Lyu,Masaru Miyagi,Edward Yu,Marvin T. Nieman
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Research Article June 5 2025
Impact of Concomitant Azoles on Ruxolitinib Treatment in Patients With GVHD: Post Hoc Analyses of REACH2 and REACH3
Zahra Mahmoudjafari,Emily Kintsch,Zhenyi Xue,Valkal Bhatt,John Galvin,Franco Locatelli,Robert Zeiser
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Research Article June 5 2025
Prospective study of immunogenicity to SARS-CoV-2 booster vaccines in multiple myeloma and Waldenström macroglobulinemia
Andrew R. Branagan,Clifton C Mo,Matthew M Lei,Joshua Gustine,Andrew J. Yee,Elizabeth O'Donnell,Jorge J. Castillo,Omar Nadeem,Catherine Flynn,Zachary Bernstein,Rie Nakamoto-Matsubara,Kirsten E. Meid,Rakesh Verma,Zachary R Hunter,Maria Luisa Guerrera,Galit Alter,Jill N. Burke,Cynthia C. Harrington,Emerentia A. Agyemang,Marilyn T. Gammon,Kathleen J. Lively,Lisette Packer,Nora Horick,Jacob P Laubach,Constantine S. Mitsiades,Nikhil C. Munshi,Kenneth C. Anderson,Steven P. Treon,Paul G Richardson,Noopur S. Raje,Shayna Sarosiek
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Research Article May 29 2025
BCLAF1 restrains stress responses in hematopoietic stem cells to support expansion and repopulation
Stephanie J Crowley,Wei Yang,Lynn S White,Jun Wu,Yanan Li,Haley Schmidt,Kyunghee Choi,Jeffrey A Magee,Jeffrey J Bednarski
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Letter May 28 2025
Emergent BAX-mutated clonal hematopoiesis after venetoclax-based therapy for breast cancer
Ing-Soo S Tiong,Tamia Nguyen,Chong Chyn Chua,Charis E Teh,Christine Muttiah,Sarah Ftouni,John F Seymour,Daniel H D Gray,Andrew W Roberts,Sarah-Jane Dawson,Geoffrey J Lindeman,Piers Blombery
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Research Article May 28 2025
Infection after CD19 chimeric antigen receptor T cell therapy for large B cell lymphoma: Real-world analysis from CIBMTR
Kitsada Wudhikarn,Megan M. Herr,Min Chen,Michael J. Martens,John H. Baird,Lohith Gowda,Hemalatha G. Rangarajan,Muhammad Bilal Abid,Mohamed A Kharfan-Dabaja,Kristen M. Williams,Siddhartha Ganguly,Jo-Anne H. Young,Akshay Sharma,Giancarlo Fatobene,Tania Jain,Christopher G. Kanakry,Dipenkumar Modi,Natalie S. Grover,Baheyeldin Salem,Marjorie Vieira Batista,Paschalis Vergidis,Dwight E. Yin,Amer M. Beitinjaneh,Amar H. Kelkar,Taiga Nishihori,Jennifer Holter-Chakrabarty,Usama Gergis,Melody Smith,Zeinab El Boghdadly,Christopher E. Dandoy,Hemant S. Murthy,Anna R. Huppler,Miguel-Angel Perales,Roy F. Chemaly,Joshua A. Hill,Marcie Riches,Jeff J. Auletta
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Research Article May 23 2025
Inaccuracies of Venous Thromboembolism Risk Assessment and Prevention Practices Among Medically Ill Patients
Brandyn Lau,Aditya Bhave,Jennifer C Yui,Rakhi P. Naik,Kathryn E. Dane,John P Lindsley,Dauryne Shaffer,Peggy S Kraus,Erik H Hoyer,Elliott R Haut,Michael B. Streiff
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Research Article May 22 2025
A Revised Prognostic Model for Patients with Acute Myeloid Leukemia and First Relapse
Niek G. Van Der Maas,Dimitri A. Breems,Clara P.W. Klerk,Thomas Pabst,Patrycja Gradowska,Abin Thomas,Bart J. Biemond,Jürgen Kuball,Catharina H.M.J. van Elssen,Otto J. Visser,Marie-Christiane Madeleine Vekemans,Carlos Graux,Johan A. Maertens,Steven Knapper,Mike Dennis,Sylvie D Freeman,Ian Thomas,Berna H Beverloo,Gerwin A Huls,Charles Craddock,Peter J.M. Valk,Paresh Vyas,Nigel H. Russell,Gert J Ossenkoppele,Bob Löwenberg,Jan J. Cornelissen,Jurjen Versluis
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Research Article May 22 2025
Impact of SARS-CoV-2 infection on bispecific antibody treatment in patients with B-cell lymphoproliferative disorders
Ángel Serna,Víctor Navarro,Moraima Jimenez,Josu Iraola-Truchuelo,Marc Bosch,Cristina García-Herce,Anna Falcó Roget,Adaia Albasanz-Puig,Isabel Ruiz-Camps,Cristina Andrés,Andrés Antón,Juliana Esperalba,Ainara Ferrero,Tomas Garcia-Cerecedo,Cecilia Carpio,Marta Crespo,Gloria Iacoboni,Ana Marín-Niebla,Francesc Bosch,Pau Abrisqueta
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Research Article May 22 2025
The SAMD1 transcription factor coordinates hematopoietic lineage differentiation and H3K4 methylation status
Meg A Schaefer,Samantha L Gomez,Venkatasai Rahul Dogiparthi,Yichao J Zhou,Pooja Roy,Suhita J Ray,Linda Chee,Sandipan Brahma, sbrahma@unmc.edu,Robert Liefke,Kyle J Hewitt
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Research Article May 22 2025
PRIDE-FTG Advances Academic Careers of Underrepresented Early-Stage Investigators Performing Blood Disorders Research
Betty Sue Pace,Oluwatoyosi Onwuemene,Athena Starlard-Davenport,Rhea-Beth Markowitz,Vahé Heboyan,Petar Datsov,Treva Rice
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Research Article May 22 2025
Circulating Tumor DNA Determinants of Response and Outcome in Relapsed/Refractory Mantle Cell Lymphoma
Leo Meriranta,Rasmus Rask Kragh Jørgensen,Annika Pasanen,Arne Kolstad,Martin Hutchings,Carsten Utoft Niemann,Tarec Christoffer El Galaly,Jon Riise,Jacob Haaber Christensen,Kristina Sonnevi,Lone Bredo Pedersen,Karin Fahl Wader,Ingrid Glimelius,Sirpa Leppä,Mats Jerkeman
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Research Article May 22 2025
Single-cell sequencing on PBMCs from HA & HB patients with inhibitors reveals different immune responses to FVIII & FIX
Enhao Li,Zekun Li,Jinzeng Wang,Haoyang Wu,Yilun Xue,Can Lou,Zhenping Chen,Feng Liu,Wenman Wu,Qiulan Ding,Runhui Wu,Xuefeng Wang,Jing Dai
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Letter May 22 2025
RAS Mutation Identifies a Poor Prognostic Molecular Subtype of Therapy-Related Myeloid Neoplasm
Chung Hoow Kok,Aref Al-Kali,Daniel Thomas,Rong He,Monika M Kutyna,Hassan B Alkhateeb,Kelly Lim,Antoine N. Saliba,Carla Toop,Aasiya Matin,Hamish S Scott,Naseema Gangat,Anna L Brown,Abhishek A. Mangaonkar,Christopher N Hahn,Kebede Begna,Kevin Hung,Patricia T. Greipp,William J Hogan,Mrinal M. Patnaik,Mithun Vinod Shah,Devendra K. Hiwase
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Letter May 22 2025
Molecular profiling of primary renal diffuse large B-cell lymphoma unravels a proclivity for immune-privileged tropism
Axel Künstner,Vera von Kopylow,Philipp Lohneis,Matthias Kümmel,Hanno M. Witte, Dr,Lorenz Bastian,Veronica Bernard, Dr,Stephanie Stölting,Kathrin Kusch,Nikolas von Bubnoff,Konrad Steinestel,Annette Arndt,Hartmut Merz, Prof,Hauke Busch,Alfred C. Feller,Niklas Gebauer
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Research Article May 16 2025
Inequalities in CAR T-Cell Therapy Access for US Patients with Relapsed/Refractory DLBCL: A SEER-Medicare Data Analysis
Andrea Chung,Jason Shafrin,Sachin Vadgama,Kristen Hurley,Miguel-Angel Perales,Leonard Clarkson Alsfeld,Sanjana Muthukrishnan,Anik R Patel,Gunjan L Shah,Richard T. Maziarz
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Letter May 14 2025
Drug development for leukemia: comprehensive analysis of clinical trials from first report to drug approval
Kellen Cristine Tjioe,Marisol Miranda Galvis,Kenza Mamouni,Thalyta Freitas,Muhannad Sharara,Brenda Santellano,Claudia Guillen,Jorge Cortes
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Research Article May 14 2025
Extramedullary Myeloma is Genomically Complex and Characterized by Near-Universal MAPK Pathway Alterations
Saurabh Zanwar,Joseph Novak,Wilson I Gonsalves,Michael Howe,Esteban Braggio,S. Vincent Rajkumar,Moritz Binder,Dragan Jevremovic,Surendra Dasari,Shaji K Kumar
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Reply May 14 2025
Response to "It might not be whether you get knocked down, but whether you..."
Wei Ying Jen,Nicholas J Short
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Letter May 14 2025
SGLT2i-associated erythrocytosis: Closing the evidence gap
Benjamin Chin-Yee,Cyrus C. Hsia
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Research Article May 12 2025
Real-World Survival Outcomes in First-Line Ibrutinib-Treated Patients with High-Risk CLL/SLL
John N. Allan,Tao Ran,Zhijie Ding,Jinghua He,Alex Bokun,Zaina P. Qureshi,Susan M. O'Brien
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Letter May 12 2025
Fatal Recurrence of IEC-HS Following Autologous Stem Cell Boost in Patients Receiving BCMA CAR-T Cell Therapy
Snegha Ananth,Nancy Eunice Torres,Bita Sahaf,Lakha Mikkilineni,Sebastian Fernandez-Pol,Darren Salmi,Robert S. Negrin,Parveen Shiraz,Melody Smith,Sushma Bharadwaj,Wen-Kai Weng,Vanessa E Kennedy,Saurabh Dahiya,Lori S. Muffly,David B Miklos,Matthew J Frank,Hitomi Hosoya,Surbhi Sidana
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