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Lapo Alinari
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Journal Articles

Targeting the DNA Damage Response through TBL1X in Mantle Cell Lymphoma

Betsy Pray, Ethan James Baiocchi, Sydney Leon, Brian Barta, Shirsha Koirala, Liudmyla Tsyba, Claire Hinterschied, Jessika Carvajal-Moreno, Ian Hout, Shamama Nishat, Udita Jindal, Neeraj Jain, Satishkumar Singh, Lalit Sehgal, Wing Keung Chan, Walter Hanel, Jack Yalowich, Robert A. Baiocchi, Lapo Alinari
Journal: Blood Advances
Blood Adv bloodadvances.2024015769.
https://doi.org/10.1182/bloodadvances.2024015769
Published: 2025
Includes: Supplemental data
Journal Articles

PRMT5 Inhibition Reduces Hyperinflammation in a Murine Model of Secondary Hemophagocytic Lymphohistiocytosis (HLH)

Fiona Brown-Burke, Rachel Saadey, Hsiao-Yin Charlene Charlene Mao, Paola Marra, Eric Brooks, Alexa Wandtke, Ian Hout, Sydney Leon, Archisha Sharma, Aneeq Yasin, Taylor Cash, Elshafa Hassan Ahmed, Ethan James Baiocchi, Stephanie Scarlett Finoti, Xiaoli Zhang, Neha Bhagwat, Kris Vaddi, Peggy Scherle, Anna Mozhenkova, Ikbale El-Ayachi, Austin D. Schenk, Shelby L. Sloan, Kaylee Whitman, JoBeth Helmig-Mason, Sheldon Steyn, Haley L. Klimaszewski, Jessica Weist, Christoph Weigel, Shirsha Koirala, Lapo Alinari, Katiri Snyder, Parvathi Ranganathan, Chia-Jo Chen, Michael B. Jordan, Robert A. Baiocchi, Polina Shindiapina
Journal: Blood Advances
Blood Adv bloodadvances.2024013651.
https://doi.org/10.1182/bloodadvances.2024013651
Published: 2025
Includes: Supplemental data
Journal Articles

Postinfusion PD-1 + CD8 + CAR T cells identify patients responsive to CD19 CAR T-cell therapy in non-Hodgkin lymphoma

Nathan Denlinger, No-Joon Song, Xiaoli Zhang, Hyeongseon Jeon, Chelsea Peterson, Yi Wang, Kelsi Reynolds, Robert M. Bolz, Jessica Miao, Chunhua Song, Dayong Wu, Wing Keung Chan, Evandro Bezerra, Narendranath Epperla, Timothy J. Voorhees, Jonathan Brammer, Adam S. Kittai, David A. Bond, Yazeed Sawalha, Audrey Sigmund, John C. Reneau, Mark P. Rubinstein, Walter Hanel, Beth Christian, Robert A. Baiocchi, Kami Maddocks, Lapo Alinari, Sumithira Vasu, Marcos de Lima, Dongjun Chung, Samantha Jaglowski, Zihai Li, Xiaopei Huang, Yiping Yang
Journal: Blood Advances
Blood Adv (2024) 8 (12): 3140–3153.
https://doi.org/10.1182/bloodadvances.2023012073
Published: 2024
Includes: Supplemental data
Journal Articles

Resistance to PRMT5-targeted therapy in mantle cell lymphoma

Mackenzie Elizabeth Long, Shirsha Koirala, Shelby Sloan, Fiona Brown-Burke, Christoph Weigel, Lynda Villagomez, Kara Corps, Archisha Sharma, Ian Hout, Margaret Harper, JoBeth Helmig-Mason, Sheetal Tallada, Zhengming Chen, Peggy Scherle, Kris Vaddi, Selina Chen-Kiang, Maurizio Di Liberto, Cem Meydan, Jonathan Foox, Daniel Butler, Christopher Mason, Lapo Alinari, Bradley W. Blaser, Robert Baiocchi
Journal: Blood Advances
Blood Adv (2023) 8 (1): 150–163.
https://doi.org/10.1182/bloodadvances.2023010554
Published: 2023
Includes: Supplemental data
Journal Articles

PRMT5 inhibition drives therapeutic vulnerability to combination treatment with BCL-2 inhibition in mantle cell lymphoma

Clinical Trials & Observations
Fiona Brown-Burke, Inah Hwang, Shelby Sloan, Claire Hinterschied, JoBeth Helmig-Mason, Mackenzie Long, Wing Keung Chan, Alexander Prouty, Ji-Hyun Chung, Yang Zhang, Satishkumar Singh, Youssef Youssef, Neha Bhagwat, Zhengming Chen, Selina Chen-Kiang, Maurizio Di Liberto, Olivier Elemento, Lalit Sehgal, Lapo Alinari, Kris Vaddi, Peggy Scherle, Rosa Lapalombella, Jihye Paik, Robert A. Baiocchi
Journal: Blood Advances
Blood Adv (2023) 7 (20): 6211–6224.
https://doi.org/10.1182/bloodadvances.2023009906
Published: 2023
Includes: Supplemental data
Journal Articles

Treatment of primary mediastinal B-cell lymphoma with dose-adjusted REPOCH during pregnancy

Kaitlin Annunzio, Michael Cackovic, David Bond, Yazeed Sawalha, Timothy J. Voorhees, Walter Hanel, Lapo Alinari, Robert Baiocchi, John Reneau, Jonathan Brammer, Kami Maddocks, Beth Christian, Narendranath Epperla
Journal: Blood Advances
Blood Adv (2023) 7 (10): 2241–2244.
https://doi.org/10.1182/bloodadvances.2022008621
Published: 2023
Journal Articles

Feasibility of high-dose methotrexate administered on day 1 of (R)CHOP in aggressive non-Hodgkin lymphomas

Clinical Trials & Observations
Megan Fleming, Ying Huang, Emily Dotson, David A. Bond, John Reneau, Narendranath Epperla, Lapo Alinari, Jonathan Brammer, Beth A. Christian, Robert A. Baiocchi, Kami Maddocks, Yazeed Sawalha
Journal: Blood Advances
Blood Adv (2022) 6 (2): 460–472.
https://doi.org/10.1182/bloodadvances.2021005999
Published: 2022
Journal Articles

Targeting phosphatidylinositol 3 kinase-β and -δ for Bruton tyrosine kinase resistance in diffuse large B-cell lymphoma

Neeraj Jain, Satishkumar Singh, Georgios Laliotis, Amber Hart, Elizabeth Muhowski, Kristyna Kupcova, Tereza Chrbolkova, Tamer Khashab, Sayan Mullick Chowdhury, Anuvrat Sircar, Fazal Shirazi, Ram Kumar Singh, Lapo Alinari, Jiangjiang Zhu, Ondrej Havranek, Philip Tsichlis, Jennifer Woyach, Robert Baiocchi, Felipe Samaniego, Lalit Sehgal
Journal: Blood Advances
Blood Adv (2020) 4 (18): 4382–4392.
https://doi.org/10.1182/bloodadvances.2020001685
Published: 2020
Includes: Supplemental data