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First Edition

Research Article July 28 2025
Cost-Effectiveness of Upfront vs. Delayed Allogeneic Hematopoietic Stem Cell Transplant for Intermediate Risk AML
Abdulrahman Alhajahjeh,Kishan Patel,Nikolai A. Podoltsev,Tariq Kewan,Jessica M. Stempel,Lourdes M Mendez,Stuart E Seropian,Lohith Gowda,Scott F. Huntington,Maximilian F. Stahl,Amer M Zeidan,George Goshua,Jan P. Bewersdorf
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Research Article July 28 2025
Targeting S100A9-mediated inflammation: A novel therapeutic approach for CLL
Angimar Uriepero-Palma,Maria Elena Marquez, Dr.,Eugenia Payque,Melanie Mediavilla-Varela,Wael Gamal,Kamira Maharaj,John J Powers,Erika Adriana Eksioglu,Julio C. Chavez,Sandra Sernbo,Florencia Palacios,Juliana Querol Rivas,Claudia Ortega,Rita Uria,Gimena dos Santos,Carolina Oliver,Ana Ines Landoni, Dra,Eva Sahakian,Pablo Oppezzo,Javier Pinilla-Ibarz
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Research Article July 28 2025
Somatic Mutations in STAG2 Are Associated with Separated Megakaryocyte Nuclear Lobes in Myelodysplastic Syndromes
Waihay J Wong,Rebecca L Zon,Christopher J. Gibson,Caleb Ho,Olga Pozdnyakova,Donna S. Neuberg,Elisabeth M. Battinelli,Marlise R. Luskin,Zuzana Tothova,Elizabeth A. Morgan,Benjamin L Ebert
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Research Article July 28 2025
A multicenter phase 1/2 trial of lenalidomide and dose-adjusted EPOCH-R in MYC-associated DLBCL
Kirk E. Cahill,James K. Godfrey,Chadi Nabhan,Justin Kline,Peter A. Riedell,Kenneth S. Cohen,Sunil Narula,Theodore G. Karrison,Jessica Robertson,Reem Karmali,Parameswaran Venugopal,Seo-Hyun Kim,Aaron P. Rapoport,Seung Tae Lee,Jennie Y. Law,Paul A.S. Fishkin,Iris Isufi,Mario Reyes Velasco, Jr,Lynne Kaminer,Sonali M. Smith
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Research Article July 24 2025
A Disrupted Adenosinergic Axis Facilitates Platelet Activation in APS: Exploring a Novel Therapeutic Target
Somanathapura K NaveenKumar,Thalia G Newman,Bruna Mazetto Fonseca,Srilakshmi Yalavarthi,Mariane C Flores Nascimento,Kaitlyn Sabb,Katarina Kmetova,Emily Chong,Kavya Sugur,Caroline H Ranger,Megan P Tompkins,Cyrus Sarosh,Jacqueline A Madison,Ajay Tambralli,Jordan K Schaefer,Michael Holinstat,Yu Zuo,Jason S. Knight
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Research Article July 24 2025
Post-transfusion recovery, quality and metabolism of short and long-term stored platelets during controlled inflammation
Stefan F. van Wonderen,Floor L.F. van Baarle,Philippa G. Phelp,Esther B. Bulle,Amy Argabright,Sanne de Bruin,Anita M. Tuip-de Boer,Chantal A. Polet,Rombout B.E. van Amstel,Endry H.T. Lim,Jimmy Schenk,Anna-Linda L. Peters,Robin van Bruggen,Julie A. Reisz,Christie Vermeulen,Thomas R.L. Klei,Bart J. Biemond,Marcella C.A. Müller,Angelo D'Alessandro,Alexander P.J. Vlaar
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Research Article July 24 2025
Real-world outcomes of brexucabtagene autoleucel for relapsed or refractory mantle cell lymphoma: a CIBMTR analysis
Nausheen Ahmed,Swetha Thiruvengadam,Mehdi Hamadani,Zhen-Huan Hu,Natalie S. Grover,Mazyar Shadman,Frederick L. Locke,James Gerson,Matthew J Frank,Lihua E Budde,Michael L Wang,Soyoung Kim,Matthew Bye,Mohamed A Kharfan-Dabaja,Craig S. Sauter,Peiman Hematti,Cameron J. Turtle,Sairah Ahmed,Amy Moskop,Brent R. Logan,Ana Nunes,David M. Dalton,Ioana Magdalena Kloos, Dr,Daniel Lee,Hairong Xu,Marcelo C. Pasquini,Alex F. Herrera
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Research Article July 24 2025
Measurable Residual Disease Detection after CAR-T May Predict Response in Patients with Large B-cell Lymphoma
Nira Krasnow,Katie Maurer,Catherine Jiawen Song,Justin Rhoades,Kan Xiong,Andjela Crnjac,Timothy Blewett,Lily Gao,Heather Jacene,Reid W Merryman,Satyen H. Gohil,Caitlyn Duffy,Liliana I. Guerrero,Jamie Dela Cruz,Mikaela McDonough,Jacquelyn O Wolff,Robert A Redd,Mike Mattie,Brodie Miles,G. Mike Makrigiorgos,Donna S. Neuberg,Scott J Rodig,Philippe Armand,Caron A. Jacobson,Viktor A. Adalsteinsson,Catherine J Wu
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Research Article July 24 2025
HLA-E[pHLA-G] Complex Specific Monoclonal Antibody Enhancing NK Activity in Multiple Myeloma
Muhammad Abu Ahmad,Olga Radinsky,Bar Kaufman,Kamran Waidha,Eman Gharra,Sharon Dim,Dinesh Babu Manikandan,Noa Ofir,Dirk Jäger,Marten Meyer,Moshe Elkabets,Kerry S. Campbell,Miri Zektser,Roi Gazit,Ory Rouvio,Frank Momburg,Angel Porgador
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Research Article July 24 2025
Nivolumab in Combination with R-CHOP for Treatment-Naïve Diffuse Large B-Cell Lymphoma: An Evaluation of Safety and Efficacy
Oluwatobi Odetola,Shuo Ma,Jane N Winter,Barbara Pro,Ishan Roy,Ping Xie,Bin Zhang,Qing Chen,George Koulogeorgas,Xinlei Mi,Ruohui Chen,Yangruijue Ma,Xiaodan Tang,Robert Bayer,Valerie Nelson,Habib Shaikh,Dean Tsarwhas,Faisal Saghir,Parameswaran Venugopal,Leo I. Gordon,Reem Karmali
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Research Article July 24 2025
Long-term results from the AGILE study of azacitidine plus ivosidenib vs placebo in newly diagnosed IDH1-mutated AML
Pau Montesinos,Dylan M. Marchione,Christian Récher,Michael Heuser,Susana Vives,Ewa Zarzycka,Jianxiang Wang,Marta Riva,Rodrigo T. Calado,Andre C. Schuh,Su-Peng Yeh,Adriana E Tron,Jianan Hui,Diego A. Gianolio,Sung Choe,Prapti A. Patel,Stéphane De Botton,Courtney D. DiNardo,Hartmut Döhner
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Letter July 21 2025
Survival after anti-CD19 CAR T-cell therapy for B-cell non-Hodgkin lymphoma and CLL with 10 years of follow-up
Tatyana Gavrilova,Lori McIntyre,Stephanie L Goff,James C. Yang,Danielle A Natrakul,Steven A Rosenberg,James N. Kochenderfer,Jennifer N Brudno
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Research Article July 17 2025
Interferon gamma rebalances immunopathological signatures in Chronic Granulomatous Disease through metabolic rewiring
Mariolina Bruno,Charlotte Kröger,Anaísa V. Ferreira,Bowen Zhang,Rutger J. Röring,Ruiqi Liu,Caspar I. van der Made,Norman van Rhijn,Lazslo Groh,Viola Klück,Nico A.F. Janssen,Wenchao Li,Diletta Rosati,Ahmed Alaswad,Helin Tercan,Jorge Saiz,Carolina Gonzalez-Riano,Martina van Uelft,Orsi Gaal,Sophie Müller,Humberto J. Ferreira,Stefanie Warnat-Herresthal,Matthias Becker,Lisa Holsten,Michael Kraut,Jonas Schulte-Schrepping,Lorenzo Bonaguro,Kristian Händler,Cristina Cunha,Manfred Schmolz,Joachim L Schultze,Leo Joosten,Coral Barbas,Mihai G Netea,Yang Li,Anna C. Aschenbrenner,Agostinho Carvalho,Frank L. van de Veerdonk
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Review Article July 17 2025
Molecular and Immunological Determinants of Long-Term Survival in Multiple Myeloma
Khanmi Kasomva,Kritika Yadav,Siegfried Janz,Binod Dhakal,Sridhar Rao
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Research Article July 17 2025
High-grade B-cell lymphoma, not otherwise specified: an LLMPP study.
Brett J Collinge,Laura K Hilton,Jasper Chun Hei Wong,Waleed Alduaij,Susana Ben-Neriah,Graham W. Slack,Pedro Farinha,Merrill Boyle,Barbara Meissner,James R. Cook,German Ott,Andreas Rosenwald,Elías Campo,Catalina Amador,Timothy C Greiner,Philipp W Raess,Joo Y. Song,Giorgio GA Inghirami,Sarah L. Ondrejka,Elaine S Jaffe,Dennis D Weisenburger,Wing C. Chan,Harald Holte,Klaus Beiske,Kai Fu,Jan Delabie,Stefania Pittaluga,Javeed Iqbal,George Wright,Kerry J. Savage,Andrew J Mungall,Louis M Staudt,Christian Steidl,Andrew L. Feldman,Ryan D Morin,Lisa M. Rimsza,David W. Scott
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Research Article July 17 2025
Novel Devimistat Results in Complete Remissions in Heavily Pre-Treated Burkitt Lymphoma in a phase II trial
Raphael E. Steiner,Liana Nikolaenko,Ranjit Nair,Venkatraman E Seshan,Swetha Thiruvengadam,Niloufer Khan,Jeremy S. Abramson,Steven M Horwitz,Matthew J. Matasar,Colette N Owens,Ildefonso Ismael Rodriguez-Rivera,David Strauss,Timothy S. Pardee,Sanjeev Luther,Sabrina Saboukoulou,Win Su Thet,Shreya Vemuri,Ariela Noy
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Research Article July 16 2025
The immune receptor FcRg-chain mediates CD36-induced platelet activation and thrombosis by oxidised low-density lipoproteins.
Katie S Wraith,Jawad S Khalil,Ahmed Aburima,Lih Tyng Cheah,Matthew S Hindle,Martin Berger,Romez Uddin,Hoor Ayub,Mary McKay,Rui-Gang Xu,Robert A S Ariëns,Mark T Kearney,Michael G Tomlinson,Khalid M. Naseem
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Research Article July 16 2025
Population-based validation of the CAR-HEMATOTOX for hematotoxicity, infections and survival after CART in R/R LBCL
Janneke W de Boer,Kylie Keijzer,Suzanne van Dorp,Pim G.N.J. Mutsaers,Anne GH Niezink,Jaap A van Doesum,Yasmina IM Serroukh,Louise W Muntendam,Astrid E Pulles,Esther J Kret,Aniko Sijs-Szabo,Jesse Oomen,Astrid MP Demandt,Wendy BC Stevens,Maria T Kuipers,Elise RA Pennings,Anne Mea Spanjaart,Marie José Kersten,Margot Jak,Lisanne Vania van Dijk,Marjolein WM van der Poel,Joost SP Vermaat,Tom van Meerten
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Research Article July 16 2025
Olutasidenib alone or combined with azacitidine in patients with mutant IDH1 myelodysplastic syndrome
Jorge E. Cortes,Jay Yang,Gail J Roboz,Shira Naomi Dinner,Eunice S. Wang,Andrew H Wei,Hua Tian,Francois di Trapani,Maria R Baer,William B Donnellan,Justin M Watts
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Research Article July 16 2025
Older matched sibling donor versus young haplo-identical donor for elderly patients with acute myeloid leukemia
Xavier Poire,Myriam Labopin,Emmanuelle Polge,Didier Blaise,Patrice Chevallier,Johan A. Maertens,Nicolaus Kröger,Caroline Besley,Stephanie Nguyen,Cristina Castilla-Llorente,Gérard Socié,Edouard Forcade,Anne Huynh,Igor Wolfgang Blau,Arnon Nagler,Jaime Sanz,Simona Piemontese,Mohamad Mohty,Fabio Ciceri
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Research Article July 11 2025
Landscape and clinicopathologic features of RAS pathway mutations in chronic myelomonocytic leukemia
Guillermo Montalban-Bravo,Sanam Loghavi,Ziyi Li,Kelly Sharon Chien,Rashmi Kanagal-Shamanna,Alex Bataller,Anuya Natu,Mark Gurney,Alexandre Bazinet,Danielle Hammond,Koji Sasaki,Gautam Borthakur,Mahesh Swaminathan,Courtney D. DiNardo,Tapan M. Kadia,Farhad Ravandi,Naval G Daver,Nicholas J. Short,Naveen Pemmaraju,Ghayas C. Issa,Terra L Lasho,Christy M. Finke,Aref Al-Kali,Clifford M Csizmar,Hassan B Alkhateeb,Naseema Gangat,Abhishek A. Mangaonkar,Carlos E. Bueso-Ramos,Ayalew Tefferi,Hagop M Kantarjian,Guillermo Garcia-Manero,Mrinal M Patnaik
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Letter July 3 2025
Incomplete Harms Reporting in Systematic Reviews of Direct Oral Factor Xa Inhibitors
Jack Rea, DO,Chase Lee,Micah Kee,Brayden Rucker,Holly Flores,Corbin Walters,Taryn Haney,Alicia Tomlin,Adam Khan,Matt Vassar
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Research Article July 2 2025
Mitochondrial iron transport via MFRN1 is required for erythroid cell cycle progression
Mark Perfetto,Aidan Danoff,Muhammad Ishfaq,Heidi Monroe,Aiden Mohideen,Meilin Chen,Jesus Tejero,Amber Stratman,Satoshi Okawa,Yvette Y Yien
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Research Article July 1 2025
Impact of transplant conditioning, NPM1 mutations, and measurable residual disease in FLT3-ITD acute myeloid leukemia
Mark J. Levis,Mehdi Hamadani,Brent R. Logan,Richard J. Jones,Anurag K Singh,Mark R Litzow,John R. Wingard,Esperanza B. Papadopoulos,Alexander E. Perl,Robert J. Soiffer,Celalettin Ustun,Masumi Ueda Oshima,Geoffrey L. Uy,Edmund K Waller,Sumithira Vasu,Melhem M. Solh,Asmita Mishra,Lori S. Muffly,Hee-Je Kim,Matthias Stelljes,Yuho Najima,Masahiro Onozawa,Kirsty J Thomson,Caroline Chen,Nahla Hasabou,Matt Rosales,Jason E. Hill,Stanley C. Gill,Rishita Nuthethi,Denise King,Adam M Mendizabal,Steven M. Devine,Mary M Horowitz,Yi-Bin Chen
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Research Article July 1 2025
Comparative Infection Risk in CAR T vs Bispecific Antibodies in B cell Lymphoma: A Systematic Review and Meta-Analysis
Herman J van Besien,Neela Easwar,Michelle Demetres,Michelle Pasciolla,Tsiporah Shore,John P Leonard,Juliet Barker,Peter Martin,Samuel Yamshon
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Letter July 1 2025
R-CHOP and R-cytarabine for transplant-ineligible MCL
Pavel Klener,Liliana Tušková,Petra Blahovcová,Marek Trněný
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Review Article June 25 2025
Efficacy and Safety of Thrombolysis for Pediatric Venous Thromboembolism: A Systematic Review and Meta-analysis
Hassan Kawtharany,Muayad Azzam,Aseel Alkhader,Marisol Betensky,Qais Hamarsha,Hadi K. Abou Zeid,Razan Mansour,Carine Tabak,Payal Patel,Sarah L. Baghdadi,Rachel Sara Bercovitz,Rukhmi Bhat,Tina T Biss,Brian R Branchford,Leonardo R. Brandão,Anthony KC Chan,E. Vincent S. Faustino,Julie Jaffray,Sophie E Jones,Bryce A Kerlin,Nicole Kucine,Riten Kumar,Christoph Male,Marie-Claude Pelland-Marcotte,Leslie Raffini,Chittalsinh M Raulji,Sarah E Sartain,Clifford M. Takemoto,Cristina Tarango,C. Heleen van Ommen,Maria C Velez,Sara K Vesely,John T Wiernikowski,Suzan Williams,Hope P Wilson,Gary Woods,Ayesha Zia,Paul Monagle,Reem A. Mustafa
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Research Article June 24 2025
Real-world data for tisagenlecleucel in patients with R/R B-ALL: subgroup analyses from the CIBMTR registry
Samuel John,Kevin J. Curran,Erin M. Hall,Amy Keating,Susanne H.C. Baumeister,Sarah Nikiforow,Timothy Driscoll,Amy Moskop,Kevin O. McNerney,Christine L. Phillips,Michael A. Pulsipher,Emily M. Hsieh,Rayne H Rouce,Marcelo C. Pasquini,Ranjan Tiwari,Jennifer Willert,Roberto Javier Ramos,Joerg Krueger,Erin Guest,Stephan A. Grupp
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Research Article June 24 2025
Point-of-care fresh CAR T cells for pediatric or young adult BCP-ALL that is relapsed/refractory or in very-high-risk first relapse
Francesca Del Bufalo,Marco Becilli,Chiara Rosignoli,Pietro Merli,Mattia Algeri,Daria Pagliara,Federica Galaverna,Michele Massa,Valeria Paganelli,Maria Giuseppina Cefalo,Linda Hanssens,Valentina Bertaina,Giuseppina Li Pira,Giovanna Leone, Dr,Matilde Sinibaldi,Stefano Di Cecca,Laura Iaffaldano,Valentina Fustaino,Biagio De Angelis,Concetta Quintarelli,Franco Locatelli
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Research Article June 20 2025
T-cell dysregulation informs radiotherapy-immunotherapy response in B-cell lymphoma: results from a Phase I trial.
Eliza A Hawkes,Jodie Palmer,Richard Khor,Sze Ting Lee,Melinda Burgess,Soi C Law,Maher K. Gandhi,Geoffrey Chong,Jake Shortt,Rakin Chowdhury,Fiona Swain,Leonid Churilov,Michael M MacManus,Charmaine Smith,Fiona Elizabeth Scott,Arina Martynchyk,Allison Barraclough,Kate Manos,Andrew M Scott,Colm Keane
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Research Article June 17 2025
Severe Parvovirus B19 Infection in Patients with Sickle Cell Disease Hospitalized in Intensive Care Unit
Segolene Gendreau,Louis-Marie Coupry,Pierre Cappy,Alexandra Beurton,Nicolas Verger,Anoosha Habibi,Maïté Agbakou,Sylvain Le Jeune,Laurent Argaud,Serge Barmo,Gauthier Blonz,Pierre Cougoul,Stéphanie Houcke,Antoine Lafarge,Arnaud Ly,Andréa Pastissier,Armand Mekontso Dessap,Slim Fourati,Nicolas de Prost
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Research Article June 12 2025
Bone marrow and blood demonstrate distinct immune reconstitution patterns and correlations with relapse post-transplant
Susan DeWolf,Jason Kuttiyara,Paola Vinci,Teng Fei,John Slingerland,Zoe A Katsamakis,Joshua A Fein,Brianna Gipson,Rachel Lorenc,Victoria Zinsmeyer,LeeAnn Marcello,Paul Giardina,William Donohoe,Gunjan L Shah,Richard J. Lin,Esperanza B. Papadopoulos,Boglarka Gyurkocza,Brian C. Shaffer,Martin S. Tallman,Ioannis Politikos,Sergio A. Giralt,Juliet Barker,Miguel-Angel Perales,Roni Tamari,Omar Abdel-Wahab,Christina Cho,Katharine Hsu,Jonathan U. Peled,Marcel R.M. van den Brink,Alan M. Hanash
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Research Article June 12 2025
Familial Forms of Chronic Lymphocytic Leukemia Have a Worse Prognosis Than Sporadic Forms: an Italian Case-Control Study
Alberto Fresa,Idanna Innocenti,Annamaria Tomasso,Candida Vitale,Alessandro Sanna,Anna Maria Frustaci,Andrea Visentin,Azzurra Romeo,Paolo Sportoletti,Annamaria Giordano,Francesca Perutelli,Roberta Murru,Francesca Romana Mauro, Hematology, Hematology, Department of Translational and Precision Medicine,Antonio Mosca,Francesca Morelli,Roberta Laureana,Andrea Galitzia,Ilaria Angeletti,Esmeralda Conte,Riccardo Moia,Giovanni D'Arena,Raffaella Pasquale,Francesco Autore,Jacopo Olivieri,Luca Stirparo,Giulia Benintende,Francesco Angotzi,Florenzia Vuono,Andrea Corbingi,Maria Ilaria Del Principe,Diana Giannarelli,Alessandra Tedeschi,Marta Coscia,Eugenio Sangiorgi,Dimitar G Efremov,Luca Laurenti
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Letter June 5 2025
Adult thymectomy is associated with increased mortality risk from cancer but not cardiovascular disease
Kameron Allen Kooshesh,Brody Harry Foy,Richard A Baylis,Karin Gustafsson,Daniel A Zlotoff,Tomas G Neilan,David T Scadden
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Research Article May 28 2025
Infection after CD19 chimeric antigen receptor T cell therapy for large B cell lymphoma: Real-world analysis from CIBMTR
Kitsada Wudhikarn,Megan M. Herr,Min Chen,Michael J. Martens,John H. Baird,Lohith Gowda,Hemalatha G. Rangarajan,Muhammad Bilal Abid,Mohamed A Kharfan-Dabaja,Kristen M. Williams,Siddhartha Ganguly,Jo-Anne H. Young,Akshay Sharma,Giancarlo Fatobene,Tania Jain,Christopher G. Kanakry,Dipenkumar Modi,Natalie S. Grover,Baheyeldin Salem,Marjorie Vieira Batista,Paschalis Vergidis,Dwight E. Yin,Amer M. Beitinjaneh,Amar H. Kelkar,Taiga Nishihori,Jennifer Holter-Chakrabarty,Usama Gergis,Melody Smith,Zeinab El Boghdadly,Christopher E. Dandoy,Hemant S. Murthy,Anna R. Huppler,Miguel-Angel Perales,Roy F. Chemaly,Joshua A. Hill,Marcie Riches,Jeff J. Auletta
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