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Journal Articles

Fatal late-onset CAR T-cell–mediated encephalitis after axicabtagene-ciloleucel in a patient with large B-cell lymphoma

Clinical Trials & Observations
Susanne Jung, Jochen Greiner, Stephanie von Harsdorf, Pavle Popovic, Roland Moll, Jens Schittenhelm, Kosmas Kandilaris, Volker Daniel, Alexander Kunz, Michael Schmitt, Peter Dreger
Journal: Blood Advances
Blood Adv (2021) 5 (19): 3789–3793.
https://doi.org/10.1182/bloodadvances.2021004889
Published: 2021
Includes: Supplemental data
Journal Articles

Increased levels of NETosis in myeloproliferative neoplasms are not linked to thrombotic events

Clinical Trials & Observations
Stefan Schmidt, Dimitri Daniliants, Elisabeth Hiller, Eberhard Gunsilius, Dominik Wolf, Clemens Feistritzer
Journal: Blood Advances
Blood Adv (2021) 5 (18): 3515–3527.
https://doi.org/10.1182/bloodadvances.2020004061
Published: 2021
Includes: Supplemental data
Journal Articles

Lymphoid blast transformation in an MPN with BCR-JAK2 treated with ruxolitinib: putative mechanisms of resistance

Clinical Trials & Observations
Justin Anthony Chen, Yanli Hou, Krishna M. Roskin, Daniel A. Arber, Charles D. Bangs, Linda B. Baughn, Athena M. Cherry, Mark D. Ewalt, Andrew Z. Fire, Laure Fresard, Hutton M. Kearney, Stephen B. Montgomery, Robert S. Ohgami, Kathryn E. Pearce, Beth A. Pitel, Jason D. Merker, Jason Gotlib
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3492–3496.
https://doi.org/10.1182/bloodadvances.2020004174
Published: 2021
Includes: Supplemental data
Journal Articles

IKZF1 alterations are not associated with outcome in 498 adults with B-precursor ALL enrolled in the UKALL14 trial

Rachel J. Mitchell, Amy A. Kirkwood, Emilio Barretta, Laura Clifton-Hadley, Emma Lawrie, SooWah Lee, Daniel Leongamornlert, David I. Marks, Andrew K. McMillan, Tobias F. Menne, Elli Papaemmanuil, Bela Patel, Pip Patrick, Clare J. Rowntree, Nahid Zareian, Krisztina Zuborne Alapi, Anthony V. Moorman, Adele K. Fielding
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3322–3332.
https://doi.org/10.1182/bloodadvances.2021004430
Published: 2021
Includes: Supplemental data
Journal Articles

Validation of the EuroClonality-NGS DNA capture panel as an integrated genomic tool for lymphoproliferative disorders

James Peter Stewart, Jana Gazdova, Nikos Darzentas, Dörte Wren, Paula Proszek, Grazia Fazio, Simona Songia, Miguel Alcoceba, Maria Eugenia Sarasquete, Patrick Villarese, Michèle Y. van der Klift, Kim C. Heezen, Neil McCafferty, Karol Pal, Mark Catherwood, Chang Sik Kim, Shambhavi Srivastava, Leonie I. Kroeze, Elizabeth Hodges, Kostas Stamatopoulos, Wolfram Klapper, Elisa Genuardi, Simone Ferrero, Michiel van den Brand, Giovanni Cazzaniga, Frederic Davi, Lesley-Ann Sutton, Ramon Garcia-Sanz, Patricia J. T. A. Groenen, Elizabeth A. Macintyre, Monika Brüggemann, Christiane Pott, Anton W. Langerak, David Gonzalez, on behalf of the EuroClonality-NGS Working Group
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3188–3198.
https://doi.org/10.1182/bloodadvances.2020004056
Published: 2021
Includes: Supplemental data
Journal Articles

Genotypes of European and Iranian patients with type 3 von Willebrand disease enrolled in 3WINTERS-IPS

Luciano Baronciani, Ian Peake, Reinhard Schneppenheim, Anne Goodeve, Minoo Ahmadinejad, Zahra Badiee, Mohammad-Reza Baghaipour, Olga Benitez, Imre Bodó, Ulrich Budde, Andrea Cairo, Giancarlo Castaman, Peyman Eshghi, Jenny Goudemand, Wolf Hassenpflug, Hamid Hoorfar, Mehran Karimi, Bijan Keikhaei, Riitta Lassila, Frank W. G. Leebeek, Maria Fernanda Lopez Fernandez, Pier Mannuccio Mannucci, Renato Marino, Nikolas Nikšić, Florian Oyen, Cristina Santoro, Andreas Tiede, Gholamreza Toogeh, Alberto Tosetto, Marc Trossaert, Eva M. K. Zetterberg, Jeroen Eikenboom, Augusto B. Federici, Flora Peyvandi
Journal: Blood Advances
Blood Adv (2021) 5 (15): 2987–3001.
https://doi.org/10.1182/bloodadvances.2020003397
Published: 2021
Includes: Supplemental data
Journal Articles

Single-nucleotide Fcγ receptor polymorphisms do not impact obinutuzumab/rituximab outcome in patients with lymphoma

Clinical Trials & Observations
Jonathan C. Strefford, Malgorzata Nowicka, Chantal E. Hargreaves, Cathy Burton, Andrew Davies, Rosalind Ganderton, Wolfgang Hiddemann, Chisako Iriyama, Wolfram Klapper, Kate V. Latham, Maurizio Martelli, Farheen Mir, Helen Parker, Kathleen N. Potter, Matthew J. J. Rose-Zerilli, Laurie H. Sehn, Marek Trněný, Umberto Vitolo, Christopher R. Bolen, Christian Klein, Andrea Knapp, Mikkel Z. Oestergaard, Mark S. Cragg
Journal: Blood Advances
Blood Adv (2021) 5 (15): 2935–2944.
https://doi.org/10.1182/bloodadvances.2020003985
Published: 2021
Includes: Supplemental data
Journal Articles

Molecular analysis of the erythroid phenotype of a patient with BCL11A haploinsufficiency

Clinical Trials & Observations
Marja W. Wessels, Marjon H. Cnossen, Thamar B. van Dijk, Nynke Gillemans, K. L. Juliëtte Schmidt, Kirsten van Lom, Divya S. Vinjamur, Steven Coyne, Ryo Kurita, Yukio Nakamura, Stella A. de Man, Rolph Pfundt, Zakia Azmani, Rutger W. W. Brouwer, Daniel E. Bauer, Mirjam C. G. N. van den Hout, Wilfred F. J. van IJcken, Sjaak Philipsen
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2339–2349.
https://doi.org/10.1182/bloodadvances.2020003753
Published: 2021
Includes: Supplemental data
Journal Articles

Cedazuridine/decitabine: from preclinical to clinical development in myeloid malignancies

Clinical Trials & Observations
Anand A. Patel, Kirk Cahill, Caner Saygin, Olatoyosi Odenike
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2264–2271.
https://doi.org/10.1182/bloodadvances.2020002929
Published: 2021
Journal Articles

Oxidized mitochondrial DNA released after inflammasome activation is a disease biomarker for myelodysplastic syndromes

Grace A. Ward, Kathy L. McGraw, Farnoosh Abbas-Aghababazadeh, Benjamin S. Meyer, Amy F. McLemore, Nicole D. Vincelette, Nghi B. Lam, Amy L. Aldrich, Najla H. Al Ali, Eric Padron, Javier Pinilla-Ibarz, Erico Masala, Valeria Santini, Olivier Kosmider, Michaela Fontenay, Pierre Fenaux, Joseph Johnson, Brooke L. Fridley, Alan F. List
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2216–2228.
https://doi.org/10.1182/bloodadvances.2020003475
Published: 2021
Includes: Supplemental data
Journal Articles

Prevalence, predictors, and outcomes of clonal hematopoiesis in individuals aged ≥80 years

Clinical Trials & Observations
Isabelle A. van Zeventer, Jonas B. Salzbrunn, Aniek O. de Graaf, Bert A. van der Reijden, H. Marike Boezen, Judith M. Vonk, Pim van der Harst, Jan Jacob Schuringa, Joop H. Jansen, Gerwin Huls
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2115–2122.
https://doi.org/10.1182/bloodadvances.2020004062
Published: 2021
Includes: Supplemental data
Journal Articles

In vivo HSPC gene therapy with base editors allows for efficient reactivation of fetal γ-globin in β-YAC mice

Chang Li, Aphrodite Georgakopoulou, Arpit Mishra, Sucheol Gil, R. David Hawkins, Evangelia Yannaki, André Lieber
Journal: Blood Advances
Blood Adv (2021) 5 (4): 1122–1135.
https://doi.org/10.1182/bloodadvances.2020003702
Published: 2021
Includes: Supplemental data
Journal Articles

Genetic factors rather than blast reduction determine outcomes of allogeneic HCT in BCR-ABL –negative MPN in blast phase

Clinical Trials & Observations
Vikas Gupta, James A. Kennedy, Jose-Mario Capo-Chichi, Soyoung Kim, Zhen-Huan Hu, Edwin P. Alyea, Uday R. Popat, Ronald M. Sobecks, Bart L. Scott, Aaron T. Gerds, Rachel B. Salit, H. Joachim Deeg, Ryotara Nakamura, Wael Saber
Journal: Blood Advances
Blood Adv (2020) 4 (21): 5562–5573.
https://doi.org/10.1182/bloodadvances.2020002727
Published: 2020
Includes: Supplemental data
Journal Articles

CD81 knockout promotes chemosensitivity and disrupts in vivo homing and engraftment in acute lymphoblastic leukemia

Anthony Quagliano, Anilkumar Gopalakrishnapillai, E. Anders Kolb, Sonali P. Barwe
Journal: Blood Advances
Blood Adv (2020) 4 (18): 4393–4405.
https://doi.org/10.1182/bloodadvances.2020001592
Published: 2020
Includes: Supplemental data
Journal Articles

Development and validation of a universal blood donor genotyping platform: a multinational prospective study

Nicholas S. Gleadall, Barbera Veldhuisen, Jeremy Gollub, Adam S. Butterworth, John Ord, Christopher J. Penkett, Tiffany C. Timmer, Carolin M. Sauer, Nieke van der Bolt, Colin Brown, Kim Brugger, Alexander T. Dilthey, Daniel Duarte, Shane Grimsley, Katja van den Hurk, John M. Jongerius, Jessie Luken, Karyn Megy, Gail Miflin, Christopher S. Nelson, Femmeke J. Prinsze, Jennifer Sambrook, Ilenia Simeoni, Michael Sweeting, Nicole Thornton, Sara Trompeter, Salih Tuna, Ram Varma, Matthew R. Walker, NIHR BioResource, John Danesh, David J. Roberts, Willem H. Ouwehand, Kathleen E. Stirrups, Augusto Rendon, Connie M. Westhoff, Emanuele Di Angelantonio, C. Ellen van der Schoot, William J. Astle, Nicholas A. Watkins, William J. Lane
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3495–3506.
https://doi.org/10.1182/bloodadvances.2020001894
Published: 2020
Includes: Supplemental data
Journal Articles

Shamay M, Kanakry JA, Low JSW, et al. CpG methylation in cell-free Epstein-Barr virus DNA in patients with EBV-Hodgkin lymphoma. Blood Adv. 2020;4(8):1624-1627.

Journal: Blood Advances
Blood Adv (2020) 4 (10): 2123.
https://doi.org/10.1182/bloodadvances.2020002179
Published: 2020
Journal Articles

CpG methylation in cell-free Epstein-Barr virus DNA in patients with EBV-Hodgkin lymphoma

Meir Shamay, Jennifer A. Kanakry, John S. W. Low, Netanel A. Horowitz, Guy Journo, Anuj Ahuja, Yonatan Eran, Elinor Barzilai, Eldad J. Dann, Jennifer Stone, Wan Lu Woo, Wen-son Hsieh, Rena R. Xian, Richard F. Ambinder
Journal: Blood Advances
Blood Adv (2020) 4 (8): 1624–1627.
https://doi.org/10.1182/bloodadvances.2020001511
Published: 2020
Journal Articles

High level of fetal-globin reactivation by designed transcriptional activator-like effector

Jun Zhan, Maria Johnson Irudayam, Yukio Nakamura, Ryo Kurita, Arthur W. Nienhuis
Journal: Blood Advances
Blood Adv (2020) 4 (4): 687–695.
https://doi.org/10.1182/bloodadvances.2019000482
Published: 2020
Includes: Supplemental data
Journal Articles

Genome editing of HBG1 and HBG2 to induce fetal hemoglobin

Jean-Yves Métais, Phillip A. Doerfler, Thiyagaraj Mayuranathan, Daniel E. Bauer, Stephanie C. Fowler, Matthew M. Hsieh, Varun Katta, Sagar Keriwala, Cicera R. Lazzarotto, Kevin Luk, Michael D. Neel, S. Scott Perry, Samuel T. Peters, Shaina N. Porter, Byoung Y. Ryu, Akshay Sharma, Devlin Shea, John F. Tisdale, Naoya Uchida, Scot A. Wolfe, Kaitly J. Woodard, Yuxuan Wu, Yu Yao, Jing Zeng, Shondra Pruett-Miller, Shengdar Q. Tsai, Mitchell J. Weiss
Journal: Blood Advances
Blood Adv (2019) 3 (21): 3379–3392.
https://doi.org/10.1182/bloodadvances.2019000820
Published: 2019
Includes: Supplemental data
Journal Articles

Replication timing alterations in leukemia affect clinically relevant chromosome domains

Juan Carlos Rivera-Mulia, Takayo Sasaki, Claudia Trevilla-Garcia, Naoto Nakamichi, David J. H. F. Knapp, Colin A. Hammond, Bill H. Chang, Jeffrey W. Tyner, Meenakshi Devidas, Jared Zimmerman, Kyle N. Klein, Vivek Somasundaram, Brian J. Druker, Tanja A. Gruber, Amnon Koren, Connie J. Eaves, David M. Gilbert
Journal: Blood Advances
Blood Adv (2019) 3 (21): 3201–3213.
https://doi.org/10.1182/bloodadvances.2019000641
Published: 2019
Includes: Supplemental data