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Journal Articles

Nf1 and Sh2b3 mutations cooperate in vivo in a mouse model of juvenile myelomonocytic leukemia

Carolina E. Morales, Elliot Stieglitz, Scott C. Kogan, Mignon L. Loh, Benjamin S. Braun
Journal: Blood Advances
Blood Adv (2021) 5 (18): 3587–3591.
https://doi.org/10.1182/bloodadvances.2020003754
Published: 2021
Includes: Supplemental data
Journal Articles

Molecular analysis of the erythroid phenotype of a patient with BCL11A haploinsufficiency

Clinical Trials & Observations
Marja W. Wessels, Marjon H. Cnossen, Thamar B. van Dijk, Nynke Gillemans, K. L. Juliëtte Schmidt, Kirsten van Lom, Divya S. Vinjamur, Steven Coyne, Ryo Kurita, Yukio Nakamura, Stella A. de Man, Rolph Pfundt, Zakia Azmani, Rutger W. W. Brouwer, Daniel E. Bauer, Mirjam C. G. N. van den Hout, Wilfred F. J. van IJcken, Sjaak Philipsen
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2339–2349.
https://doi.org/10.1182/bloodadvances.2020003753
Published: 2021
Includes: Supplemental data
Journal Articles

HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation

Scott A. Peslak, Eugene Khandros, Peng Huang, Xianjiang Lan, Carly L. Geronimo, Jeremy D. Grevet, Osheiza Abdulmalik, Zhe Zhang, Belinda M. Giardine, Cheryl A. Keller, Junwei Shi, Ross C. Hardison, Gerd A. Blobel
Journal: Blood Advances
Blood Adv (2020) 4 (18): 4560–4572.
https://doi.org/10.1182/bloodadvances.2020002475
Published: 2020
Includes: Supplemental data
Journal Articles

High level of fetal-globin reactivation by designed transcriptional activator-like effector

Jun Zhan, Maria Johnson Irudayam, Yukio Nakamura, Ryo Kurita, Arthur W. Nienhuis
Journal: Blood Advances
Blood Adv (2020) 4 (4): 687–695.
https://doi.org/10.1182/bloodadvances.2019000482
Published: 2020
Includes: Supplemental data
Journal Articles

Genome editing of HBG1 and HBG2 to induce fetal hemoglobin

Jean-Yves Métais, Phillip A. Doerfler, Thiyagaraj Mayuranathan, Daniel E. Bauer, Stephanie C. Fowler, Matthew M. Hsieh, Varun Katta, Sagar Keriwala, Cicera R. Lazzarotto, Kevin Luk, Michael D. Neel, S. Scott Perry, Samuel T. Peters, Shaina N. Porter, Byoung Y. Ryu, Akshay Sharma, Devlin Shea, John F. Tisdale, Naoya Uchida, Scot A. Wolfe, Kaitly J. Woodard, Yuxuan Wu, Yu Yao, Jing Zeng, Shondra Pruett-Miller, Shengdar Q. Tsai, Mitchell J. Weiss
Journal: Blood Advances
Blood Adv (2019) 3 (21): 3379–3392.
https://doi.org/10.1182/bloodadvances.2019000820
Published: 2019
Includes: Supplemental data
Journal Articles

BCL2L1 is associated with γ-globin gene expression

Yan Dai, Elmutaz M. Shaikho, Jessica Perez, Carolyn A. Wilson, Lesley Y. Liu, Mitchell R. White, John J. Farrell, David H. K. Chui, Paola Sebastiani, Martin H. Steinberg
Journal: Blood Advances
Blood Adv (2019) 3 (20): 2995–3001.
https://doi.org/10.1182/bloodadvances.2019032243
Published: 2019
Journal Articles

Fetal hemoglobin does not inhibit Plasmodium falciparum growth

Natasha M. Archer, Nicole Petersen, Manoj T. Duraisingh
Journal: Blood Advances
Blood Adv (2019) 3 (14): 2149–2152.
https://doi.org/10.1182/bloodadvances.2019000399
Published: 2019
Journal Articles

The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells

Xianjiang Lan, Eugene Khandros, Peng Huang, Scott A. Peslak, Saurabh K. Bhardwaj, Jeremy D. Grevet, Osheiza Abdulmalik, Hongxin Wang, Cheryl A. Keller, Belinda Giardine, Josue Baeza, Emily R. Duffner, Osama El Demerdash, Xiaoli S. Wu, Christopher R. Vakoc, Benjamin A. Garcia, Ross C. Hardison, Junwei Shi, Gerd A. Blobel
Journal: Blood Advances
Blood Adv (2019) 3 (10): 1586–1597.
https://doi.org/10.1182/bloodadvances.2019032318
Published: 2019
Includes: Supplemental data
Journal Articles

Phthalides serve as potent modulators to boost fetal hemoglobin induction therapy for β-hemoglobinopathies

Wei-Ren Chen, Chia-Cheng Chou, Chia C. Wang
Journal: Blood Advances
Blood Adv (2019) 3 (9): 1493–1498.
https://doi.org/10.1182/bloodadvances.2019031120
Published: 2019
Includes: Supplemental data
Journal Articles

Biological impact of α genes, β haplotypes, and G6PD activity in sickle cell anemia at baseline and with hydroxyurea

Clinical Trials & Observations Global Advances
Françoise Bernaudin, Cécile Arnaud, Annie Kamdem, Isabelle Hau, Françoise Lelong, Ralph Epaud, Corinne Pondarré, Serge Pissard
Journal: Blood Advances
Blood Adv (2018) 2 (6): 626–637.
https://doi.org/10.1182/bloodadvances.2017014555
Published: 2018
Journal Articles

g(HbF) : a genetic model of fetal hemoglobin in sickle cell disease

Clinical Trials & Observations
Kate Gardner, Tony Fulford, Nicholas Silver, Helen Rooks, Nikolaos Angelis, Marlene Allman, Siana Nkya, Julie Makani, Jo Howard, Rachel Kesse-Adu, David C. Rees, Sara Stuart-Smith, Tullie Yeghen, Moji Awogbade, Raphael Z. Sangeda, Josephine Mgaya, Hamel Patel, Stephen Newhouse, Stephan Menzel, Swee Lay Thein
Journal: Blood Advances
Blood Adv (2018) 2 (3): 235–239.
https://doi.org/10.1182/bloodadvances.2017009811
Published: 2018
Includes: Supplemental data
Journal Articles

Low fetal hemoglobin percentage is associated with silent brain lesions in adults with homozygous sickle cell disease

Clinical Trials & Observations
David Calvet, Titien Tuilier, Nicolas Mélé, Guillaume Turc, Anoosha Habibi, Nassim Ait Abdallah, Loubna Majhadi, François Hemery, Myriam Edjlali, Frédéric Galacteros, Pablo Bartolucci
Journal: Blood Advances
Blood Adv (2017) 1 (26): 2503–2509.
https://doi.org/10.1182/bloodadvances.2017005504
Published: 2017
Journal Articles

Associations of α-thalassemia and BCL11A with stroke in Nigerian, United States, and United Kingdom sickle cell anemia cohorts

Clinical Trials & Observations Global Advances
Santosh L. Saraf, Titilola S. Akingbola, Binal N. Shah, Chinedu A. Ezekekwu, Omowunmi Sonubi, Xu Zhang, Lewis L. Hsu, Mark T. Gladwin, Roberto F. Machado, Richard S. Cooper, Victor R. Gordeuk, Bamidele O. Tayo
Journal: Blood Advances
Blood Adv (2017) 1 (11): 693–698.
https://doi.org/10.1182/bloodadvances.2017005231
Published: 2017
Journal Articles

KLF1 directly activates expression of the novel fetal globin repressor ZBTB7A/LRF in erythroid cells

Laura J. Norton, Alister P. W. Funnell, Jon Burdach, Beeke Wienert, Ryo Kurita, Yukio Nakamura, Sjaak Philipsen, Richard C. M. Pearson, Kate G. R. Quinlan, Merlin Crossley
Journal: Blood Advances
Blood Adv (2017) 1 (11): 685–692.
https://doi.org/10.1182/bloodadvances.2016002303
Published: 2017
Includes: Supplemental data
Journal Articles

Hemoglobin variants identified in the Uganda Sickle Surveillance Study

Global Advances
Beverly A. Schaefer, Charles Kiyaga, Thad A. Howard, Grace Ndeezi, Arielle G. Hernandez, Isaac Ssewanyana, Mary C. Paniagua, Christopher M. Ndugwa, Jane R. Aceng, Russell E. Ware
Journal: Blood Advances
Blood Adv (2016) 1 (1): 93–100.
https://doi.org/10.1182/bloodadvances.2016000950
Published: 2016
Includes: Supplemental data