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Journal Articles

FT-4202, an oral PKR activator, has potent antisickling effects and improves RBC survival and Hb levels in SCA mice

Archana Shrestha, Mengna Chi, Kimberly Wagner, Astha Malik, Jennifer Korpik, Adam Drake, Keertik Fulzele, Sylvie Guichard, Punam Malik
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2385–2390.
https://doi.org/10.1182/bloodadvances.2020003604
Published: 2021
Includes: Supplemental data
Journal Articles

MetAP2 inhibition modifies hemoglobin S to delay polymerization and improves blood flow in sickle cell disease

Melanie Demers, Sarah Sturtevant, Kevin R. Guertin, Dipti Gupta, Kunal Desai, Benjamin F. Vieira, Wenjing Li, Alexandra Hicks, Ayman Ismail, Bronner P. Gonçalves, Giuseppe Di Caprio, Ethan Schonbrun, Scott Hansen, Faik N. Musayev, Martin K. Safo, David K. Wood, John M. Higgins, David R. Light
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1388–1402.
https://doi.org/10.1182/bloodadvances.2020003670
Published: 2021
Includes: Supplemental data