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RESEARCH LETTER| March 6, 2025

Response and Outcomes of Patients with IDH1/2 Mutated Accelerated/Blast-Phase Myeloproliferative Neoplasms

Leah A. Goldberg,

Leah A. Goldberg

1University of Chicago Medical Center, Chicago, IL

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James J. Yoon,

James J. Yoon

2Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

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Hannah Johnston,

Hannah Johnston

3Department of Medicine, Section of Hematology-Oncology, University of Chicago, Chicago, IL

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Marta B. Davidson,

Marta B. Davidson

4Department of Internal Medicine, Section of Hematology, Yale School of Medicine and Yale Cancer Center, New Haven, CT

https://orcid.org/0000-0001-6978-1368

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Alexa Siddon,

Alexa Siddon

5Departments of Laboratory Medicine and Pathology, Yale School of Medicine, New Haven, CT

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Rory M. Shallis,

Rory M. Shallis

6Department of Internal Medicine, Section of Hematology, Yale School of Medicine and Yale Cancer Center, New Haven, CT

https://orcid.org/0000-0002-8542-2944

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Evan C. Chen,

Evan C. Chen

7Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA

https://orcid.org/0000-0002-9218-215X

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Madelyn Burkart,

Madelyn Burkart

8Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, NC

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Timothy S. Oh,

Timothy S. Oh

9Division of Hematology and Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL

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Sunil G. Iyer,

Sunil G. Iyer

10Division of Hematology and Oncology, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY

https://orcid.org/0000-0002-2507-9347

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Ellen Madarang,

Ellen Madarang

11University of Miami Sylvester Comprehensive Cancer Center, Miami, FL

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Chandrasekar Muthiah,

Chandrasekar Muthiah

12Department of Internal Medicine, Medical College of Wisconsin, Milwaukee, WI

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Joshua Kassner,

Joshua Kassner

13Division of Hematology and Medical Oncology, Weill Department of Medicine, Cornell University, New York, NY

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Raajit K. Rampal,

Raajit K. Rampal

14Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY

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Guru Subramanian Guru Murthy,

Guru Subramanian Guru Murthy

15Division of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI

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Terrence Bradley,

Terrence Bradley

11University of Miami Sylvester Comprehensive Cancer Center, Miami, FL

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Yasmin Abaza,

Yasmin Abaza

9Division of Hematology and Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL

https://orcid.org/0000-0002-9156-7912

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Jacqueline S. Garcia,

Jacqueline S. Garcia

7Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA

https://orcid.org/0000-0003-2118-6302

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Vikas Gupta,

Vikas Gupta

4Department of Internal Medicine, Section of Hematology, Yale School of Medicine and Yale Cancer Center, New Haven, CT

https://orcid.org/0000-0002-1419-8607

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Kristen M. Pettit,

Kristen M. Pettit

16Division of Hematology and Medical Oncology, Department of Internal Medicine, University of Michigan Medical School, Michigan Medicine, Ann Arbor, MI

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Olatoyosi Odenike,

Olatoyosi Odenike

3Department of Medicine, Section of Hematology-Oncology, University of Chicago, Chicago, IL

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John F. Cursio,

John F. Cursio

17Department of Public Health Sciences, University of Chicago, Chicago, IL

https://orcid.org/0000-0003-2131-1767

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Anand A. Patel

Anand A. Patel

3Department of Medicine, Section of Hematology-Oncology, University of Chicago, Chicago, IL

https://orcid.org/0000-0002-0296-8686

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Blood Neoplasia 100089.

https://doi.org/10.1016/j.bneo.2025.100089

Article history

Submitted:

December 19, 2024

Accepted:

February 5, 2025

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Citation

Leah A. Goldberg, James J. Yoon, Hannah Johnston, Marta B. Davidson, Alexa Siddon, Rory M. Shallis, Evan C. Chen, Madelyn Burkart, Timothy S. Oh, Sunil G. Iyer, Ellen Madarang, Chandrasekar Muthiah, Joshua Kassner, Raajit K. Rampal, Guru Subramanian Guru Murthy, Terrence Bradley, Yasmin Abaza, Jacqueline S. Garcia, Vikas Gupta, Kristen M. Pettit, Olatoyosi Odenike, John F. Cursio, Anand A. Patel; Response and Outcomes of Patients with IDH1/2 Mutated Accelerated/Blast-Phase Myeloproliferative Neoplasms. Blood Neoplasia 2025; 100089. doi: https://doi.org/10.1016/j.bneo.2025.100089

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Author notes

Data Sharing Statement: de-identified data will be made available upon reasonable request to corresponding author

© 2025 American Society of Hematology. Published by Elsevier Inc. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution. All other rights reserved.

2025

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