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First Edition

Review Article June 19 2025
Current Landscape of Frontline and Relapsed Follicular Lymphoma Trials
Lawrence Cheng Kiat Ng,Carla Casulo
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Research Article June 19 2025
GCK Inhibition Enhances Iberdomide Anti-Myeloma Effects by Promoting IKZF1 Degradation via a CRBN-Independent Mechanism
Shirong Li,Josefine Krüger,Guifen Liu,Huihui Ma,Michael S. Hughes,Rajshekhar Chakraborty,Divaya Bhutani,Markus Y. Mapara,Christophe Marcireau,Suzanne Lentzsch,Jing Fu
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Brief Report June 14 2025
Treatment discontinuation due to toxicity for patients with acute myeloid leukemia receiving intensive chemotherapy
Suravi Raychaudhuri,Megan Othus,Mary-Elizabeth M. Percival,Guillermo Garcia-Manero,Frederick R. Appelbaum,Harry P. Erba,Jacob S. Appelbaum
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Research Article June 9 2025
Correlates of Organ Damage in Advanced Systemic Mastocytosis Patients Enrolled in Clinical Trials of Avapritinib
Emily C. Liang,Cecelia Perkins,Rong Lu,Hongliang Shi,Saša Dimitrijević,Justin Abuel,Cheryl Langford,Parveen Abidi,Lenn Fechter,William Shomali,Jason Gotlib
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Research Article June 9 2025
Real-world outcomes with ibrutinib in relapsed or refractory mantle cell lymphoma: A Danish population-based study
Trine Trab,Iman Chanchiri,Ahmed Ludvigsen Al-Mashhadi,Emma Berggreen Dall,Stine Rasch,Mette Johansen,Simon Husby,Mikkel Runason Simonsen,Michael Roost Clausen,Thomas Stauffer Larsen,Jacob Haaber Christensen,Robert Schou Pedersen,Mikael Frederiksen,Mats Jerkeman,Christian Bjørn Poulsen,Laura Mors Haunstrup,Peter Brown,Tarec Christoffer El-Galaly,Kirsten Grønbæk
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Research Article June 9 2025
A Phase 1 Study of IO-202, an Anti-LILRB4 Antibody, in Chronic Myelomonocytic Leukemia and Acute Myeloid Leukemia
Ahmed Aribi,Gabriel N. Mannis,Yazan F. Madanat,Brian A. Jonas,Neil Dunavin,Gail J. Roboz,Deepa Jeyakumar,Guillermo Garcia-Manero,Hongtao Liu,Hetty E. Carraway,Jennifer N. Saultz,William Blum,Gary Schiller,Tao Huang,Paul Woodard,Barbara Klencke,X. Charlene Liao,Hong Xiang,Daniel A. Pollyea,Courtney D. DiNardo
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Research Article June 3 2025
V-FAST: A phase 1b master trial to investigate CPX-351 combined with targeted agents in adults with newly diagnosed AML
Vinod A. Pullarkat,Mark Levis,James McCloskey,Gabriel N. Mannis,Stephen A. Strickland,Amir T. Fathi,Tara L. Lin,Vijaya R. Bhatt,Thuva Vanniyasingam,Divya Chakravarthy,Yana Lutska,Stefan Faderl,Ronald S. Cheung,Harry P. Erba
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Research Article June 3 2025
Targeting scavenger receptor class B type 1 with a bioinspired ligand induces apoptosis or ferroptosis in AML
Adam Y. Lin,Jonathan S. Rink,Eva Yang,Sara Small,Jessica J. Gerber,Taylor J Zak,Jessica Altman,Yasmin Abaza,Leonidas C. Platanias,Leo I Gordon,C. Shad Thaxton
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Brief Report June 3 2025
Beat AML genetic risk stratification model in an older VEN/HMA-treated AML patient cohort
Fieke W. Hoff,Ashley O. Yocum,Uma M. Borate,Alice S. Mims,John C. Byrd,Yazan F. Madanat
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Research Article June 3 2025
Minimal residual disease measurement in blood by mass spectrometry identifies long-term responders in multiple myeloma.
Tadeusz Kubicki,Benjamin A Derman,Jennifer H Cooperrider,Anna Puła,David Barnidge,Dominik Dytfeld,Ken Jiang,Andrzej J Jakubowiak
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Research Article May 19 2025
Replication of a GWAS signal near HLA-DQA2 with AML using a disease-only cohort and external population-based controls
Rose Laflamme,Véronique Lisi,Josée Hébert,Guy Sauvageau,Sébastien Lemieux,Vincent-Philippe Lavallée,Guillaume Lettre
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Research Article May 19 2025
Outcomes and factors influencing survival in patients with diffuse large B cell lymphoma: a population-based analysis
Inna Y Gong,Michael Crump,Anca Prica,Andrew Calzavara,Ning Liu,Tiana Kordbacheh,Danielle Rodin,David Hodgson,Lee Mozessohn,Matthew Cheung,John Kuruvilla
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Research Article May 19 2025
PPARγ-induced Upregulation of Fatty Acid Metabolism Confers Resistance to Venetoclax and Decitabine Therapy in AML.
Kotoko Yamatani,Tatsuro Watanabe,Kaori Saito,Abdullah Khasawneh,Abhishek Maiti,Zhihong Zeng,Kala Hayes,Shinya Kimura,Courtney D. DiNardo,Xiaoping Su,Shuko Nojiri,Yasushi Okazaki,Michael Andreeff,Marina Konopleva,Yoko Tabe
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Research Article May 19 2025
NAMPT haploinsufficiency is a collateral lethal therapeutic vulnerability in high-risk myeloid malignancies with TP53 inactivation
Madhavi D. Senagolage,Hunter Z. Blaylock,Saira Khan,Sarah J. Skuli,Martin P. Carroll,Megan E. McNerney
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Research Article May 19 2025
An Antibody-Drug Conjugate Targeting VpreB1 for the Treatment of B-cell Acute Lymphoblastic Leukemia
Peter M. Gordon,Robin L. Williams,Jason Ostergaard,Keegan C. Lee,Hannah N. Bui,Joseph M. Muretta,Bridget S. Wilson,Thomas Beder,Claudia D. Baldus,Luke Lambert,Benjamin E. Deonovic,Timothy Singleton,Sarah K. Tasian,Stuart S. Winter
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Research Article May 12 2025
Real world performance of the CALGB 10403 regimen in young adults in the United States
Brandon DaSilva,Alicia Darwin,Amy Zhang,Rutu D. Vyas,Kathryn Russell,Jason S. Gilbert,Virginia Tan,Susan Feldt,Hannah Johnston,Emily C Liang,Adam S. DuVall,Michaela Liedtke,Wendy Stock,Ryan D. Cassaday,Marc Schwartz,Jessica T. Leonard,Lori S. Muffly,Marlise R. Luskin
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Brief Report May 11 2025
Temporal clonal relatedness between myeloid neoplasm and nodal T follicular helper cell lymphoma: a retrospective study
Mingfei Yan,Robert Stuver,Kai Shiang Lin,William T. Johnson,Steven M. Horwitz,Ahmet Dogan,Wenbin Xiao
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Research Article May 11 2025
Prognostic impact of Extranodal Disease on PET/CT in Follicular Lymphoma: Results from a Validation Study with ECOG 2408
Frederique St-Pierre,Stephen M. Broski,Zequn Sun,Masha Kocherginsky,Betsy Laplant,Matthew J. Maurer,Andrew Quon,Lucia Baratto,Hatice Savas,Lale Kostakoglu,Jane N. Winter,Thomas E. Witzig,Brad Kahl,Andrew M. Evens,Leo I. Gordon
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Research Article May 11 2025
Tagraxofusp, a CD123-Targeted Therapy, for Chronic Myelomonocytic Leukemia: Final Results of a Phase 1/2 Study
Mrinal M. Patnaik,Haris Ali,Eunice S. Wang,Abdulraheem Yacoub,James M. Foran,Vikas Gupta,Gary J. Schiller,Don Ambrose Stevens,Moshe Talpaz,Sarah Wall,Terra L Lasho,Abhishek A. Mangaonkar,Talha Badar,Ross Lindsay,Antonio Galleu,Ira Gupta,Naveen Pemmaraju,Guillermo Garcia-Manero
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Research Article May 11 2025
Dose escalation study of the HLA-A2-WT1 CD3 bispecific antibody RO7283420 in relapsed/refractory acute myeloid leukemia
Martin Hutchings,Koorosh Korfi,Pau Montesinos,Armando Santoro,Hsin-An Hou,Pilar Martinez-Sanchez,Susana Vives,Sara Galimberti,Tsai-Yun Chen,Marco Frigeni,Sylvain Garciaz,Olga Salamero Garcia,Su-Peng Yeh,Karen Yee,Jordi Esteve,Ashish Bajel,Shaun Fleming,Anne Catherine Bretz,Jan Attig,Min Sun,Sina Nassiri,Tobias Rutishauser,Christian Klein,Y. May Ma,Gabriel Schnetzler,Stephanie Vauleon,Huixin Yu,Teresa Barata,Muriel Richard,Silke Simon,Heather Hinton,Nino Keshelava,Marion Subklewe
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Research Article May 11 2025
A Comparative Assessment of Molecular-Based Prognostic Models in CMML
Luis E. Aguirre,Najla Al Ali,Somedeb Ball,Akriti G. Jain,David Sallman,Andrew Kuykendall,Alison R. Walker,Kendra Sweet,Jeffrey E. Lancet,Eric Padron,Rami S. Komrokji
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Research Article May 11 2025
Gut Faecalibacterium abundance in patients with plasma cell disorders is associated with survival after autologous HSCT
Erin A. Dean,Arkaprava Roy,Rick Y. Lin,Raad Z. Gharaibeh,Derek M. Li,Josee Gauthier,Christian Jobin,John R. Wingard
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Research Article April 25 2025
Targeting HASPIN kinase disrupts SR protein-mediated RNA splicing and synergizes with BCL-2 inhibitor venetoclax in AML
Mengdan Liu,Ming Yan,Amanda G. Davis,Samuel A. Stoner,Edward D. Ball,Dong-Er Zhang
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Research Article April 25 2025
The oral CDK9 inhibitor voruciclib combined with venetoclax in patients with relapsed/refractory acute myeloid leukemia
Yesid Alvarado-Valero,Rachel J. Cook,Shira N. Dinner,Michael Keng,Kebede H. Begna,Nathalie Javidi-Sharifi,Sameem Abedin,Monzr M. Al Malki,Vijaya Raj Bhatt,Prabhu Rajagopalan,Min Tang,Sandra E. Wiley,Richard G. Ghalie,Matthew S. Davids
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Research Article April 25 2025
Checkpoint immunotherapy is associated with preferential activation of tumor-antigen specific CD4+ T cells in MDS.
Elizabeth A. Griffiths,Pragya Srivastava,Eduardo Cortes Gomez,Junko Matsuzaki,Kunle Odunsi,Laura W. Dillon,Devdeep Mukherjee,Christopher S. Hourigan,Jacqueline Peng,Shovik Bandyopadhyay,Kai Tan,Kristopher M. Attwood,Joseph B. Kuechle,Prashant K. Singh,Jianmin Wang,Michael J. Nemeth
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Research Article April 25 2025
Activity of STAMP inhibitors in ABL2 rearranged Acute Lymphoblastic Leukemia is dependent on the Abl2 SH3 domain
Elias Lagonik,Elyse C. Page,John B. Bruning,Laura N. Eadie,Susan L. Heatley,Matthew Greenwood,Chun Y. Fong,Andrew S. Moore,David T. Yeung,Timothy P. Hughes,Deborah L. White
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Research Article April 16 2025
Olfactory Receptors as Tumor Suppressors in Cutaneous T-Cell Lymphoma via p38γ Pathway Modulation
Xu Hannah Zhang,Hongzhi Li,Jack Hsiang,Ching-Hong Chen,Sangkil Nam,Henry Wong,Xiwei Wu,Weidong Hu,Jack Shively,Steven T. Rosen
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Research Article April 16 2025
Outcomes of Myeloablative Allogeneic Hematopoietic Cell Transplantation with Omidubicel vs Haploidentical and Unrelated Donor Sources
Chenyu Lin,Smitha Sivaraman,Gautam Sajeev,Yan Song,Chunyi Xu,Chujun He,James E. Signorovitch,Heayoung Shin,Xiao-Ying Tang,Mei-Jie Zhang,Linda J. Burns,Ronit Simantov,Mitchell E. Horwitz
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