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Author notes

Data Sharing Statement:

Sequencing data are available via EGA, St. Jude Cloud or TARGET/GDC as defined in Online Supplemental Table 1. Information about TARGET can be found at http://ocg.cancer.gov/ programs/target. Other data generated in this study are available in the Online Supplemental Tables or upon request to the corresponding author. Data from scDNA + protein sequencing analyses are pending deposition in the European Genome-Phenome Archive (EGA) which is hosted by the European Bioinformatics Institute (EBI).

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