The symptoms and signs referable to the cardiovascular system that are associated with anemia are discussed, and the physiologic adjustments to anemia that take place in the cardiovascular system are considered. The capacity for adjustment when anemia develops gradually, appears to be very great. The remarkable changes found in the cardiovascular system in cases of sickle cell anemia may be the result of adjustments to severe anemia of exceptional chronicity.

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© 1946 by American Society of Hematology, Inc.
1946
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