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Research Article March 20 2025
Clonal hematopoiesis is clonally unrelated to multiple myeloma and is associated with specific microenvironmental changes
Marta Lionetti,Margherita Scopetti,Antonio Matera,Akihiro Maeda,Alessio Marella,Francesca Lazzaroni,Giancarlo Castellano,Sonia Fabris,Stefania Pioggia,Silvia Lonati,Alfredo Marchetti,Alessandra Cattaneo,Marta Tornese,Antonino Neri, Dr,Claudia Leoni,Loredana Pettine,Valentina Traini,Ilaria Silvestris,Marzia Barbieri,Giuseppina Fabbiano,Domenica Ronchetti,Elisa Taiana,Claudio De Magistris,Matteo Claudio Da Via',Francesco Passamonti,Niccolò Bolli
Letter March 20 2025
Diabetes Mellitus and APOL1 Genotype Increase the Risk for Chronic Kidney Disease Progression in Sickle Cell Disease
Research Article March 19 2025
NKG2D-mediated cytotoxicity of CD4 cytotoxic T cells in multiple myeloma
Review Article March 19 2025
PI3Kγ in leukemia: class IB PI3 kinase reemerges as a cancer-intrinsic target
Review Article March 19 2025
Role of allo-HCT in "nonclassical" MPNs and MDS/MPNs: recommendations from the PH&G Committee and the CMWP of the EBMT
Nicola Polverelli,Juan Carlos Hernandez-Boluda,Francesco Onida,Carmelo Gurnari,Kavita Raj,Tomasz Czerw,Michelle Kenyon,Marie Robin,Katja Sockel,Annalisa Ruggeri,Isabel Sánchez-Ortega,Daniel A. Arber,Luca Arcaini,Fernando Barroso Duarte,Giorgia Battipaglia,Yves Chalandon,Fabio Ciceri,Nicholas C.P. Cross,Joanna Drozd-Sokolowska,Vaneuza Araújo Moreira Funke,Nico Gagelmann,Naseema Gangat,Jason Gotlib,Paola Guglielmelli,Claire N. Harrison,Gabriela S Hobbs,Tania Jain,Joseph D. Khoury,Jean-Jacques Kiladjian,Nicolaus Kröger,Luca Malcovati,Massimo Martino,Ruben Mesa,Attilio Orazi,Eric Padron,Francesca Palandri,Francesco Passamonti,Mrinal M. Patnaik,Naveen Pemmaraju,Deepti H. Radia,Andreas Reiter,Domenico Russo,Christof Scheid,Ayalew Tefferi,Alessandro M. Vannucchi,Daniel Howard Wiseman,Ibrahim Yakoub-Agha,Donal P McLornan
Brief Report March 19 2025
Low rates of chronic graft-versus-host disease with ruxolitinib maintenance following allogeneic HCT
Zachariah DeFilipp,Haesook T Kim,Laura W. Knight,Suzanne M. O'Connor,Shilton E. Dhaver,Meghan White,Bhagirathbhai Dholaria,Mark A Schroeder,Sumithira Vasu,Sameem M Abedin,Jooho Chung,Areej El-Jawahri,Matthew J. Frigault,Steven L. McAfee,Richard A. Newcomb,Paul V O'Donnell,Thomas R. Spitzer,Yi-Bin Chen,Gabriela S Hobbs
Brief Report March 18 2025
Enhanced α2-3 linked sialylation determines the extended half-life of CHO-rVWF
Letter March 18 2025
STAT1-mediated interferon signatures associate with preclinical JAK-inhibitor sensitivity in T-cell acute lymphoblastic leukemia
Jason Xu,Jonathan H Sussman,Austin Yang,Satoshi Yoshimura,Jianzhong Hu,Changya Chen,Tiffaney L Vincent,Shovik Bandyopadhyay,Elizabeth Y Li,Tristan Lee Lim,Omar Elghawy,Adam Barsouk,Damjan Karanfilovski,Shira L Wald,Gregory M Chen,David Wei Wu,Haley Newman,Alexander Li,Yusha Sun,Chia-Hui Chen,Kathrin Maria Bernt,Brent L. Wood,Stuart Sheldon Winter,Kimberly P. Dunsmore,Elizabeth A. Raetz,Meenakshi Devidas,Stanley B Pounds,Mignon L. Loh,Stephen P Hunger,Mark Chiang,Caroline Diorio,Danika Di Giacomo,Petri Pölönen,Charles G. Mullighan,Jun J Yang,Kai Tan,David Trent Teachey
Brief Report March 16 2025
The neutrophil antigen 3a/b polymorphism in SLC44A2 unexpectedly encodes Csa/Csb red cell antigens
Romain Duval,Alissa Soudry,Jonathan De Oliveira Rios,Sarah Liane Linguet,Miguel Taillepierre,Graziella Matesic,Alexandre Raneri,Guy Laiguillon,Emilie Le Toriellec,Emilie-Fleur Gautier,Damien Vainqueur,Jérôme Babinet,Cécile Masson,jean Christophe Gelly,Caroline Le Van Kim,Marc Romana,Dawei Chen,Sentot Santoso,Berengere Koehl,Thierry Peyrard,Slim Azouzi
Review Article March 16 2025
How I treat type 1 plasminogen deficiency
Brief Report March 16 2025
Therapeutic switch from plasma to recombinant ADAMTS13 for patients with congenital TTP from Japanese real-world data
Discussion March 16 2025
Proteostasis Disruption in Inherited Bone Marrow Failure Syndromes
Discussion March 16 2025
Pathogenesis of Paroxysmal Nocturnal Hemoglobinuria
Letter March 16 2025
Lymphoid Malignancies in patients with Shwachman-Diamond Syndrome
Helen D. Reed,Hyunwoo Do,Edie A. Weller,Marian H. Harris,Christopher R. Reilly,Harrison K. Tsai,Jason E. Farrar,Bonnie W. Lau,Lauren Pommert,Christopher J. Gamper,Ian Atkinson,Katherine Coyne,Margret Joos,Sara Katherine Loveless,Sarah K. Steltz,Leah Cheng,Maggie Malsch,Kasiani C. Myers,Akiko Shimamura
Research Article March 16 2025
Itacitinib for the Prevention of IEC Therapy-Associated CRS: Results From the Two-Part Phase 2 INCB 39110-211 Study
Research Article March 16 2025
Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome
Changya Chen,Jason Xu,Jonathan H Sussman,Tiffaney L Vincent,Joseph S Tumulty,Satoshi Yoshimura,Fatemeh Alikarami,Wenbao Yu,Yang-Yang Ding,Chia-Hui Chen,Elizabeth Y Li,Austin Yang,Xiaohuan Qin,Shovik Bandyopadhyay,Jacqueline Jiahui Peng,Petri Pölönen,Haley Newman,Brent Wood,Jianzhong Hu,Rawan Shraim,Andrew D Hughes,Caroline Diorio,Lahari Uppuluri,Gongping Shi,Theresa Ryan,Tori Fuller,Mignon L. Loh,Elizabeth A. Raetz,Stephen P Hunger,Stanley B Pounds,Charles G. Mullighan,David Frank,Jun J Yang,Kathrin Maria Bernt,David Trent Teachey,Kai Tan
Research Article March 16 2025
Beyond genotype: challenges in predicting disease risk for carriers of biallelic perforin variants
Oliver Wegehaupt,Oleg Borisov,Elena Sieni,Florian Oyen,Jasmin Mann,Maria Luisa Coniglio,Aurora Chinnici, PhD,Francesco Pegoraro,Linda Beneforti,Kimberly C Gilmour,Despina Moshous,Geneviève de Saint Basile,Wenying Zhang,Rebecca A Marsh,Carmela De Fusco,Katharina Wustrau,Fabio Timeus,Concetta Micalizzi,Eberhard Gunsilius,Laine Hosking,Sharon Choo,Sujal Ghosh,Anna Köttgen,Kai Lehmberg,Stephan Ehl
Research Article March 16 2025
A TIM-3-Fc decoy secreted by engineered T cells improves CD19 CAR-T cell therapy in B-cell acute lymphoblastic leukemia
Aïda Falgàs,Rodrigo Lázaro-Gorines,Samanta Romina Zanetti,Laura Rubio-Pérez,Alba Martinez-Moreno,Meritxell Vinyoles,Mercedes Guerrero-Murillo,Narcís Fernandez-Fuentes,Heleia Roca-Ho,Néstor Tirado,Carla Panisello,Talía Velasco-Hernandez,Andrea Mayado,Alba Pérez-Pons,Eulalia Genesca,Josep-Maria Ribera,Jordi Ribera,Mireia Camos,Manuel Ramírez-Orellana,Eduardo Anguita,Paola Ballerini,José Luis Fuster,Manel Juan,Europa Azucena Azucena González-Navarro,Franco Locatelli,Ronald W. W. Stam,Sergio Querol,Pablo Velasco,Valentín Ortiz-Maldonado,Nuria Martínez-Cibrian,Julio Delgado,Alberto Orfao,Luis Alvarez-Vallina,Clara Bueno,Pablo Menendez
Research Article March 16 2025
Ruxolitinib combined with dexamethasone for adult patients with newly diagnosed hemophagocytic lymphohistiocytosis in China
Research Article March 16 2025
Loss of BCL7A Permits IRF4 Transcriptional Activity and Cellular Growth in Multiple Myeloma
Research Article March 16 2025
Genetic and epigenetic mechanisms of GPRC5D loss after anti-GPRC5D CAR T-cell therapy in multiple myeloma
Research Article March 16 2025
Blunted CD40-responsive enhancer activation in CREBBP-mutant lymphomas can be restored by enforced CD4 T-cell engagement
Haopeng Yang,Wenchao Zhang,Vida Ravanmehr,Guiling Cui,Kevin Bowman,Ruidong Chen,Jared Henderson,Shyanne Ruby Lockman,Estela Rojas,Ashley Lauren Wilson,Sydney Parsons,Ariel Mechaly,Leslie Regad,Ahmed Haouz,Christopher R. Flowers,Sattva S. Neelapu,Loretta J. Nastoupil,Richard Eric Davis,Qing Deng,Fernando Rodrigues Lima,Michael R Green
Research Article March 16 2025
HLA-haploidentical stem cell transplantation for chronic granulomatous disease: an EBMT-IEWP retrospective study
Quentin Riller,Mathias M Hauri-Hohl,Su Han Lum,Jeroen Knippenberg,Tiarlan Sirait,Alexandra Laberko,Khalid Halahleh,Hasan Hashem,Musa Karakukcu,Henrik Sengeloev,Fulvio Porta,Benedicte Bruno,Marco Zecca,Serap Aksoylar,Vincent Barlogis,Catharina Schuetz,Jochen Buechner,Maura Faraci,Claudia Wehr,Wolfgang Holter,Karin M Mellgren,Franco Locatelli,Antonio Pérez-Martínez,Felipe Suarez,Despina Moshous,Andrew R Gennery,Dmitry Balashov,Michael H Albert,Mary A Slatter,Tayfun Güngör,Bénédicte Neven
Research Article March 16 2025
Safety and efficacy of rilzabrutinib vs placebo in adults with immune thrombocytopenia: the phase 3 LUNA3 study
David J Kuter,Waleed Ghanima,Nichola Cooper,Howard Allen Liebman,Lei Zhang,Yu Hu,Yoshitaka Miyakawa,Wojciech Homenda,Luisa Elena Elena Morales Galindo, MD,Ana Lisa Basquiera,Chuen Wen Tan,Guray Saydam, Prof Dr,Marie Luise Hütter-Krönke,Chatree Chai-Adisaksopha,David Gomez-Almaguer,Huy Tran,Ho-Jin Shin,Ademar Dantas da Cunha Junior,Zsolt Lazar,Cristina Pascual-Izquierdo,Ilya Kirgner,Elisa Lucchini,Ganna Kuzmina,Michael Fillitz,Sylvain Audia,Minakshi Taparia,Matias Cordoba,Remco Diab,Mengjie Yao,Imene Gouia, Dr.,Michelle Lee,Ahmed Abd Almalik Daak
Research Article March 12 2025
Large-scale dependency and drug screens characterize the therapeutic vulnerabilities of Multiple Myeloma with 1q+
Romanos Sklavenitis-Pistofidis,Elizabeth D Lightbody,Mairead Reidy,Junko Tsuji,Jean-Baptiste Alberge,Michelle P Aranha,Daniel Lewis Heilpern-Mallory,Harvey G. Roweth,Daisy Huyng,Stephen Jun Fei Chong,Anna Y. Chung,Jeremy Zhang,Liam Hackett,Nicholas J Haradhvala,Ting Wu,Nang Kham Su,Brianna Berrios,Saveliy Belkin,Ankit K. Dutta,Ryan A Knudson,Carolyn Brandt,Patricia T. Greipp,Matthew S. Davids,Maria Papaioannou,Gad Getz,Irene M Ghobrial,Salomon Manier
Research Article March 12 2025
Efficacy of Combined CD38 and PD1 Inhibition with Isatuximab and Cemiplimab for Relapsed/Refractory NK/T-Cell Lymphoma
Research Article March 12 2025
A Controlled Trial for Preventing Priapism in Sickle Cell Anemia: Hydroxyurea plus Placebo vs Hydroxyurea plus Tadalafil
Ibrahim Musa Idris,Aminu Abba Yusuf,Ismail Isah Ismail,Awwal Musa Borodo,Mustapha Shuaibu Hikima,Shehu Abubakar Kana,Tukur Aliyu,Kabiru Musan Gedu,Atiku Usman Jibrillah, MBBS, FWACS,Sani Ali Aji,Aisha Kuliya-Gwarzo,Kabeer Bello Mohammed,Jamil A . Galadanci,Rukayya Sunusi Alkassim,Mohammad Abba Suwaid,Nafiu Hussaini,Mark Rodeghier,Arthur Louis Burnett, II,Michael R DeBaun
Research Article March 11 2025
Social Determinants of Health and Access to Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia
Natalie Wuliji,Salene M.W. Jones,Ted A Gooley,Aaron T Gerds,Bruno C. Medeiros,Paul J Shami,John P Galvin,Kehinde U.A. Adekola,Selina M. Luger,Maria R Baer,David A. Rizzieri,Tanya Wildes,Eunice S. Wang,Mikkael A. Sekeres,Sudipto Mukherjee,Julie Smith,Mitchell Garrison,Kiarash Kojouri,Jacob S Appelbaum,Mary-Elizabeth M. Percival,Brenda M Sandmaier,Stephanie J. Lee,Frederick Appelbaum,Rayne H. Rouce,Mohamed L. Sorror
Research Article March 11 2025
Clonal Hematopoiesis Landscape in Frequent Blood Donors
Darja Karpova,Hector Huerga Encabo, Dr,Elisa Donato,Silvia Calderazzo,Michael Scherer,Miriam Llorian-Sopena,Aino-Maija Leppä,Roberto Würth,Patrick Stelmach,Despoina Papazoglou,Alessandra Ferrelli,Steven Ngo,Iuliia Kotova,Sabine Harenkamp,Kai Zimmer,Dominik Wolf,Jasper Panten,John Reed,Adriana Przybylla,Torsten Tonn,Annette Kopp-Schneider,Lars Velten,John F. DiPersio,Terrence N Wong,Dominique Bonnet, Prof,Halvard Bonig,Andreas Trumpp
Research Article March 7 2025
Safety and efficacy of a fitusiran antithrombin-based dose regimen in people with hemophilia A or B: the ATLAS-OLE study
Brief Report February 28 2025
The bone marrow NK cell profile predicts MRD negativity in patients with multiple myeloma treated with daratumumab-based therapy
Charlotte L.B.M. Korst,Sabrin Tahri,Carolien Duetz,Wassilis S.C. Bruins,A. Vera de Jonge,Madelon M.E. de Jong,Cathelijne Fokkema,Febe Smits,Kaz Groen,Christie P.M. Verkleij,Kristine A. Frerichs,Natalie Papazian,Mark van Duin,Gregory van Beek,Remco Hoogenboezem,Thomas Baardemans,Giada Dal Collo,Elodie C.G. Stoetman,Meliha Cosovic,Inoka Twickler,Rosa Rentenaar,Merve Eken,Paola M. Homan-Weert,Elona Saraci,Mattia D'Agostino,Vincent H.J. van der Velden,Mathijs Arnoud Sanders,Francesca Gay,Annemiek Broijl,Philippe Moreau,Pieter Sonneveld,Sonja Zweegman,Tuna Mutis,Tom Cupedo,Niels W.C.J. van de Donk
Review Article February 28 2025
Exploring the thrombus niche: Lessons learned and potential therapeutic opportunities
Review Article February 28 2025
The Future of Follicular Lymphoma Management: Strategies on the Horizon
Research Article February 27 2025
Decoding functional hematopoietic progenitor cells in the adult human lung
Research Article February 26 2025
Integrated cross-linking by TG2 and FXIII generates hepatoprotective fibrin(ogen) deposits in injured liver
Research Article February 26 2025
Histo-blood group ABO system transferase plasma levels and risk of future venous thromboembolism: The HUNT Study
Research Article February 26 2025
Ibrutinib Lead-in followed by Venetoclax Plus Ibrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia - SAKK 34/17
Research Article February 26 2025
STING activation improves T-cell-engaging immunotherapy for acute myeloid leukemia
Research Article February 26 2025
Up-front Blinatumomab Improves MRD Clearance and Outcome in Adult Ph− B-lineage ALL: the GIMEMA LAL2317 Phase 2 Study
Renato Bassan,Sabina Chiaretti,Irene Della Starza,Alessandra Santoro,Orietta Spinelli,Manuela Tosi,Loredana Elia,Deborah Cardinali,Maria Stefania De Propris,Matteo Piccini,Federico Lussana,Mario Annunziata,Patrizia Chiusolo,Patrizia Zappasodi,Erika Borlenghi,Matteo Leoncin,Catello Califano,Monica Bocchia,Francesco Di Raimondo,Francesco Grimaldi,Mario Tiribelli, MD,Anna Candoni,Albana Lico,Ernesta Audisio,Monia Lunghi,Anna Maria Mianulli,Mariangela Di Trani,Valentina Arena,Monica Messina,Alfonso Piciocchi,Paola Fazi,Alessandro Rambaldi,Robin Foà
Research Article February 26 2025
A CEBPB/IL-1β/TNF-α Feedback Loop Drives Drug Resistance to Venetoclax and MDM2 Inhibitors in Monocytic Leukemia
Basil Allen,Daniel Bottomly,Thomas Köhnke,Anthony Wang,Hsin-Yun Lin,Kara Johnson,Isabel Kenna,Anastatia Streltsova,Emma Martin,Reid Chen,Lindsey Savoy,Nicola Long,Peter Ryabinin,Stephen E Kurtz,Christopher A Eide,Amy Carlos,Andy Kaempf,Tingting Liu,Cristina E. Tognon,Robert Searles,Paul D. Piehowski,Sara J.C. Gosline,Anupriya Agarwal,Bill H Chang,Michelle Barton,Brian J Druker,Shannon K. McWeeney,Ravindra Majeti,Jeffrey W. Tyner,Haijiao Zhang
Research Article February 26 2025
The MURANO study: final analysis and retreatment/crossover substudy results of VenR for patients with relapsed/refractory CLL
Arnon P. Kater,Rosemary Anne Harrup,Thomas J Kipps,Barbara Eichhorst,Carolyn Owen,Sarit E. Assouline,Nicole Lamanna,Tadeusz Robak, Prof.,Javier de la Serna,Ulrich Jaeger,Guillaume Cartron,Marco Montillo,Clemens Mellink,Anton W. Langerak,Brenda Chyla,Relja Popovic,Yanwen Jiang,Rosemary Millen,Marcus Lefebure,Maria Thadani-Mulero,Michelle Boyer,John F Seymour
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