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Journal Articles

Inhibition of PIM Kinases Targets Synthetic Vulnerabilities and Enhances Antigen Presentation in B-Cell Lymphoma

Patrizia Mondello, MD PhD MSc, Chiara Tarantelli, PhD, Luciano Cascione, PhD, Alberto Arribas, PhD, Andrea Rinaldi, Anas Younes, MD, Francesco Bertoni, MD

Blood (2019) 134 (Supplement_1): 2858.

https://doi.org/10.1182/blood-2019-125123

Published: 2019

Journal Articles

Secreted Factors Determine Resistance to Idelalisib in Marginal Zone Lymphoma Models of Resistance

Alberto J Arribas, Sara Napoli, Eugenio Gaudio, PhD, Luciano Cascione, PhD, Alessandra Di Veroli, Chiara Tarantelli, PhD, Filippo Spriano, Antonella Zucchetto, Francesca Maria Rossi, PhD, Andrea Rinaldi, Anastasios Stathis, MD, Georg Stuessi, MD, Valter Gattei, MD, Gabriele Cruciani, Emanuele Zucca, MD, Davide Rossi, MD PhD, Francesco Bertoni, MD

Blood (2019) 134 (Supplement_1): 2569.

https://doi.org/10.1182/blood-2019-124299

Published: 2019

Journal Articles

The ETS Inhibitors Yk-4-279 and TK-216 Interfere with Spib and Synergize with Lenalidomide in Diffuse Large B Cell Lymphoma of the Activated B Cell-like Type (ABC DLBCL)

Elaine Y Chung, PhD, Filippo Spriano, Ivo Kwee, PhD, Sara Napoli, Chiara Tarantelli, PhD, Eugenio Gaudio, PhD, Luciano Cascione, PhD, Andrea Cavalli, Alberto Arribas, PhD, Andrea Rinaldi, Davide Rossi, MD PhD, Emanuele Zucca, MD, Anastasios Stathis, MD, Katti Jessen, PhD, Brian J Lannutti, PhD, Jeffrey Toretsky, MD, Francesco Bertoni, MD

Blood (2017) 130 (Supplement 1): 2810.

https://doi.org/10.1182/blood.V130.Suppl_1.2810.2810

Published: 2017

Journal Articles

Targeting the PI3K/mTOR Pathway in Lymphoma with PQR309 and PQR620: Single Agent Activity and Synergism with the BCL2 Inhibitor Venetoclax

Chiara Tarantelli, PhD, Eugenio Gaudio, PhD, Petra Hillmann, Filippo Spriano, Ivo Kwee, PhD, Andrea Rinaldi, PhD, Anastasios Stathis, Emanuele Zucca, Doriano Fabbro, Vladimir Cmiljanovic, Francesco Bertoni, MD

Blood (2016) 128 (22): 3017.

https://doi.org/10.1182/blood.V128.22.3017.3017

Published: 2016

Journal Articles

Identification of DNA Copy Number Variations Associated with the Clinical Outcome in Young Mantle Cell Lymphoma Patients Treated with Cytarabine-Based High Dose Sequential Chemotherapy and Autologous Stem Cell Transplantation in the Prospective from the MCL0208 Phase III Trial from Fondazione Italiana Linfomi (FIL)

Andrea Rinaldi, PhD, Simone Ferrero, Ivo Kwee, PhD, Davide Rossi, MD PhD, Alessio Bruscaggin, Valeria Spina, Fary Diop, Filippo Ballerini, MD, Filippo Gherlinzoni, MD, Fabio Benedetti, Michael Mian, MD, Caterina Stelitano, MD, Elisa Doni, MD, Alessandra Flavia Salvi, Sergio Cortelazzo, Marco Ladetto, MD, Gianluca Gaidano, MD PhD, Francesco Bertoni, MD

Blood (2016) 128 (22): 4099.

https://doi.org/10.1182/blood.V128.22.4099.4099

Published: 2016

Journal Articles

Analysis of the Early Clonal Dynamics in Ibrutinib-Treated Chronic Lymphocytic Leukemia

Blood (2016) 128 (22): 4367.

https://doi.org/10.1182/blood.V128.22.4367.4367

Published: 2016

Journal Articles

The Pan Class-I PI3K Inhibitor Copanlisib Has Preclinical Activity in Mantle Cell Lymphoma, Marginal Zone Lymphoma and Chronic Lymphocytic Leukemia As Single Agent and in Combination with Other Targeted and Conventional Agents

Eugenio Gaudio, PhD, Ivo Kwee, PhD, Filippo Spriano, Chiara Tarantelli, PhD, Andrea Rinaldi, PhD, Thibaud Jourdan, Melanie Berthold, Alberto Arribas, PhD, Anastasios Stathis, Davide Rossi, MD PhD, Martin Lange, PhD, Oliver Politz, Emanuele Zucca, Francesco Bertoni, MD

Blood (2016) 128 (22): 4185.

https://doi.org/10.1182/blood.V128.22.4185.4185

Published: 2016

Journal Articles

Identification of Anti-Lymphoma Biomarkers of Response to the Anti-CD37 Antibody Drug Conjugate (ADC) IMGN529

Eugenio Gaudio, PhD, Chiara Tarantelli, PhD, Alberto Arribas, PhD, Luciano Cascione, PhD, Ivo Kwee, PhD, Andrea Rinaldi, PhD, Maurilio Ponzoni, MD, Roberta Pittau Bordone, Georg Stussi, MD, Davide Rossi, MD PhD, Emanuele Zucca, Anastasios Stathis, Callum Sloss, PhD Molecular Biology, Francesco Bertoni, MD

Blood (2016) 128 (22): 4187.

https://doi.org/10.1182/blood.V128.22.4187.4187

Published: 2016

Journal Articles

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

Blood (2016) 127 (2): 221–232.

https://doi.org/10.1182/blood-2014-12-614503

Published: 2016

Includes: Supplemental data

Journal Articles

DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features

Blood (2015) 125 (12): 1922–1931.

https://doi.org/10.1182/blood-2014-08-596247

Published: 2015

Includes: Supplemental data

Journal Articles

Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL

Blood (2015) 125 (10): 1578–1588.

https://doi.org/10.1182/blood-2014-07-587790

Published: 2015

Includes: Supplemental data

Journal Articles

The BET-Bromodomain Inhibitor OTX015 Is Active As a Single Agent and in Combination with Other Targeted Drugs in Preclinical Models of Mantle Cell Lymphoma

Elena Bernasconi, B.Sc., Chiara Tarantelli, Eugenio Gaudio, PhD, Ivo Kwee, Andrea Rinaldi, Luciano Cascione, Anastasios Stathis, MD, Maria Eugenia Riveiro, MD PhD, Emanuele Zucca, MD, Francesco Bertoni

Blood (2014) 124 (21): 3113.

https://doi.org/10.1182/blood.V124.21.3113.3113

Published: 2014

Journal Articles

BET Bromodomain Inhibitor OTX015 Affects the Expression of Micrornas Involved in the Pathogenesis of Diffuse Large B-Cell Lymphoma

Luciano Cascione, Eugenio Gaudio, PhD, Elena Bernasconi, B.Sc., Chiara Tarantelli, Andrea Rinaldi, Monica Testoni, B.Sc., Riccardo Bomben, Valter Gattei, Ivo Kwee, PhD, Anastasios Stathis, MD, Maria Eugenia Riveiro, MD PhD, Emanuele Zucca, MD, Francesco Bertoni

Blood (2014) 124 (21): 4495.

https://doi.org/10.1182/blood.V124.21.4495.4495

Published: 2014

Journal Articles

Identification of a New Subclass of ALK Negative Anaplastic Large Cell Lymphoma Expressing Aberrant Levels of ERBB4 Transcripts

Irene Scarfò, Elisa Pellegrino, Ivo Kwee, Luca Agnelli, Elisabetta Mereu, Elisa Bergaggio, Francesco Abate, Rodolfo Machiorlatti, Katia Messana, Andrea Rinaldi, Enrico Tiacci, Sara Serra, Silvia Deaglio, Antonino Neri, Brunangelo Falini, Raul Rabadan, Francesco Bertoni, Giorgio Inghirami, MD, Roberto Piva

Blood (2014) 124 (21): 1679.

https://doi.org/10.1182/blood.V124.21.1679.1679

Published: 2014

Journal Articles

The Novel PI3K/mTOR Dual Inhibitor PQR309 in Pre-Clinical Lymphoma Models: Demonstration of Anti-Tumor Activity As Single Agent and in Combination and Identification of Gene Expression Signatures Associated with Response

Chiara Tarantelli, Eugenio Gaudio, PhD, Ivo Kwee, PhD, Andrea Rinaldi, Matteo Stifanelli, Elena Bernasconi, B.Sc., Chiara Barassi, Petra Hillmann, Anastasios Stathis, MD, Laura Carrassa, Massimo Broggini, Georg Stussi, MD, Doriano Fabbro, Paul Hebeisen, Frances Betts, Andreas Wicki, Emanuele Zucca, MD, Vladimir Cmiljanovic, Francesco Bertoni

Blood (2014) 124 (21): 1782.

https://doi.org/10.1182/blood.V124.21.1782.1782

Published: 2014

Journal Articles

Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma

Blood (2014) 123 (11): 1681–1690.

https://doi.org/10.1182/blood-2013-05-500595

Published: 2014

Includes: Supplemental data

Journal Articles

Genome-Wide Promoter Methylation Of Hairy Cell Leukemia (HCL)

Andrea Rinaldi, PhD, Ivo Kwee, PhD, Afua A. Mensah, PhD, Davide Rossi, Meena Kanduri, PhD, Richard Rosenquist, Emanuele Zucca, MD, Gianluca Gaidano, Francesco Bertoni, MD, Francesco Forconi, MD, PhD

Blood (2013) 122 (21): 3757.

https://doi.org/10.1182/blood.V122.21.3757.3757

Published: 2013

Journal Articles

Genetic Factors Predicting The Response To BET Bromodomain Inhibitors In Lymphoma Lead To New Synergistic Combinations

Eugenio Gaudio, PhD, Ivo Kwee, PhD, Andrea Rinaldi, PhD, Michela Boi, PhD, Elena Bernasconi, B.Sc., Monica Testoni, B.Sc., Anastasios Stathis, MD, Patrice Herait, MD, Kay Noel, PhD, Giorgio Inghirami, Emanuele Zucca, MD, Francesco Bertoni, MD

Blood (2013) 122 (21): 3070.

https://doi.org/10.1182/blood.V122.21.3070.3070

Published: 2013

Journal Articles

Genome-Wide Promoter Methylation Profiling Of Splenic Marginal Zone Lymphoma (SMZL) Identifies Two Subgroups Of Patients With Distinct Genetic and Biologic Features and Different Outcomes

Blood (2013) 122 (21): 77.

https://doi.org/10.1182/blood.V122.21.77.77

Published: 2013

Journal Articles

Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome

Blood (2013) 122 (15): 2673–2682.

https://doi.org/10.1182/blood-2013-03-489518

Published: 2013

Includes: Supplemental data

NARROW

Inhibition of PIM Kinases Targets Synthetic Vulnerabilities and Enhances Antigen Presentation in B-Cell Lymphoma

Secreted Factors Determine Resistance to Idelalisib in Marginal Zone Lymphoma Models of Resistance

The ETS Inhibitors Yk-4-279 and TK-216 Interfere with Spib and Synergize with Lenalidomide in Diffuse Large B Cell Lymphoma of the Activated B Cell-like Type (ABC DLBCL)

Targeting the PI3K/mTOR Pathway in Lymphoma with PQR309 and PQR620: Single Agent Activity and Synergism with the BCL2 Inhibitor Venetoclax

Analysis of the Early Clonal Dynamics in Ibrutinib-Treated Chronic Lymphocytic Leukemia

The Pan Class-I PI3K Inhibitor Copanlisib Has Preclinical Activity in Mantle Cell Lymphoma, Marginal Zone Lymphoma and Chronic Lymphocytic Leukemia As Single Agent and in Combination with Other Targeted and Conventional Agents

Identification of Anti-Lymphoma Biomarkers of Response to the Anti-CD37 Antibody Drug Conjugate (ADC) IMGN529

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features

Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL

The BET-Bromodomain Inhibitor OTX015 Is Active As a Single Agent and in Combination with Other Targeted Drugs in Preclinical Models of Mantle Cell Lymphoma

BET Bromodomain Inhibitor OTX015 Affects the Expression of Micrornas Involved in the Pathogenesis of Diffuse Large B-Cell Lymphoma

Identification of a New Subclass of ALK Negative Anaplastic Large Cell Lymphoma Expressing Aberrant Levels of ERBB4 Transcripts

The Novel PI3K/mTOR Dual Inhibitor PQR309 in Pre-Clinical Lymphoma Models: Demonstration of Anti-Tumor Activity As Single Agent and in Combination and Identification of Gene Expression Signatures Associated with Response

Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma

Genome-Wide Promoter Methylation Of Hairy Cell Leukemia (HCL)

Genetic Factors Predicting The Response To BET Bromodomain Inhibitors In Lymphoma Lead To New Synergistic Combinations

Genome-Wide Promoter Methylation Profiling Of Splenic Marginal Zone Lymphoma (SMZL) Identifies Two Subgroups Of Patients With Distinct Genetic and Biologic Features and Different Outcomes

Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome

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American Society of Hematology

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ASH Publications

American Society of Hematology

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