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Journal Articles

Deciphering the Immune Microenvironment in Waldenstrom's Macroglobulinemia

Blood (2023) 142 (Supplement 1): 4690.

https://doi.org/10.1182/blood-2023-188408

Published: 2023

Journal Articles

Remodeling of the Immune Microenvironment By Oncogenic MYD88 Dictates Immunotherapy Responses across Indolent and Aggressive B-Cell Lymphomas

Jon Celay, Miriam Recalde, María Victoria Revuelta, Marta Larrayoz, Sara Rodriguez, Maria J Garcia-Barchino, Jennifer R. Chapman-Fredricks, Teresa Lozano, Juan J Lasarte, Ming Q. Du, Izidore S. Lossos, Sergio Roa, Aldo Roccaro, Miguel Canales, Felipe Prosper, Bruno Paiva, Leandro Cerchietti, Jose A. Martinez-Climent

Blood (2023) 142 (Supplement 1): 431.

https://doi.org/10.1182/blood-2023-173394

Published: 2023

Journal Articles

Lymphoma-Derived IL-10 Is a Key Immunomodulatory Factor at the Tumor Microenvironment of Activated B-Cell Diffuse Large B-Cell Lymphoma and Influences In Vivo Responses to Immunotherapy

Marcos Garcia-Lacarte, Sara C Grijalba, Francisco J Novo, Adrián Arnaiz-Leché, Javier Melchor, Marién Pascual, Enrique Goñi, Sandra Morales-Sánchez, María A Burrell, Oscar Blanco, Iñigo Clemente-Larramendi, Jose A Martinez-Climent, Noelia Casares, Juan J Lasarte, Pablo Sarobe, Miguel Canales, Sergio Roa

Blood (2023) 142 (Supplement 1): 716.

https://doi.org/10.1182/blood-2023-177612

Published: 2023

Journal Articles

Targeting the immune microenvironment in Waldenström macroglobulinemia via halting the CD40/CD40-ligand axis

Blood (2023) 141 (21): 2615–2628.

https://doi.org/10.1182/blood.2022019240

Published: 2023

Includes: Supplemental data

Journal Articles

Activation of the PP2A-B56α heterocomplex synergizes with venetoclax therapies in AML through BCL2 and MCL1 modulation

Irene Peris, Silvia Romero-Murillo, Elena Martínez-Balsalobre, Caroline C. Farrington, Elena Arriazu, Nerea Marcotegui, Marta Jiménez-Muñoz, Cristina Alburquerque-Prieto, Andrea Torres-López, Vicente Fresquet, Jose A. Martínez-Climent, Maria C. Mateos, Maria L. Cayuela, Goutham Narla, Maria D. Odero, Carmen Vicente

Blood (2023) 141 (9): 1047–1059.

https://doi.org/10.1182/blood.2022016466

Published: 2023

Includes: Supplemental data

Journal Articles

Immune Biomarkers of Survival and Severe Infection in Newly Diagnosed Multiple Myeloma (NDMM) Patients (pts) Treated with the Backbone Regimen Lenalidomide and Dexamethasone (Rd)

Catarina Maia, Noemi Puig, Cristina Pérez Ruiz, Maria Teresa Cedena Romero, Camila Guerrero, Marta Larrayoz, Cirino Botta, Norma C. Gutierrez, María José Calasanz, Maria Luisa Martin-Ramos, Miguel Hernández, Laura Rosinol Dachs, Esther González Garcia, Felipe De Arriba, Albert Oriol, Veronica Gonzalez-Calle, Fernando Escalante, Javier de la Rubia, Mercedes Gironella Mesa, Rafael Rios, Ricarda Belen Garcia Sanchez, Jose Maria Arguiñano PEREZ, Adrian Alegre, Jesus Martin, María del Carmen Couto Caro, Maria Casanova, Mario Arnao Herraiz, Ernesto Pérez, Sebastián Garzón López, Marta Sonia Gonzalez Perez, Guillermo Martín-Nuñez, Adriana Rossi, Morton Coleman, Cristina Encinas, Ana M. Vale, Ana Isabel Teruel, María Cortés Rodríguez, Jose A. Martinez-Climent, Juan-José Lahuerta, Joan Bladé Creixenti, Ruben Niesvizky, Jesús San-Miguel, Maria-Victoria Mateos, Bruno Paiva

Blood (2022) 140 (Supplement 1): 4200–4203.

https://doi.org/10.1182/blood-2022-163058

Published: 2022

Journal Articles

DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features

Blood (2015) 125 (12): 1922–1931.

https://doi.org/10.1182/blood-2014-08-596247

Published: 2015

Includes: Supplemental data

Journal Articles

Inhibition of the Methyltransferase G9a with Small Molecules As a New Therapeutic Strategy for Treatment of Hematological Malignancies

Edurne San José-Enériz, PhD, Xabier Agirre, PhD, Obdulia Rabal, PhD, Sergio Roa, PhD, Amaia Vilas-Zornoza, PhD, Estíbaliz Miranda, Ana Ugarte, PhD, Juan Antonio Sanchez-Arias, PhD, Bruno Paiva, PhD, Jesus F. San Miguel, Jose A. Martinez-Climent, MD PhD, Julen Oyarzabal, PhD, Felipe Prosper, MD

Blood (2014) 124 (21): 3532.

https://doi.org/10.1182/blood.V124.21.3532.3532

Published: 2014

Journal Articles

Acquired mutations in BCL2 family proteins conferring resistance to the BH3 mimetic ABT-199 in lymphoma

Vicente Fresquet, Melissa Rieger, Carlo Carolis, Maria J. García-Barchino, Jose A. Martinez-Climent

Blood (2014) 123 (26): 4111–4119.

https://doi.org/10.1182/blood-2014-03-560284

Published: 2014

Includes: Supplemental data

Journal Articles

Genome-Wide Promoter Methylation Profiling Of Splenic Marginal Zone Lymphoma (SMZL) Identifies Two Subgroups Of Patients With Distinct Genetic and Biologic Features and Different Outcomes

Blood (2013) 122 (21): 77.

https://doi.org/10.1182/blood.V122.21.77.77

Published: 2013

Journal Articles

Downregulation of FOXP1 is required during germinal center B-cell function

Ainara Sagardoy, Jose I. Martinez-Ferrandis, Sergio Roa, Karen L. Bunting, María Angela Aznar, Olivier Elemento, Rita Shaknovich, Lorena Fontán, Vicente Fresquet, Ignacio Perez-Roger, Eloy F. Robles, Linde De Smedt, Xavier Sagaert, Ari Melnick, Jose A. Martinez-Climent

Blood (2013) 121 (21): 4311–4320.

https://doi.org/10.1182/blood-2012-10-462846

Published: 2013

Includes: Supplemental data

Journal Articles

Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma

Elena Cubedo, Andrew J. Gentles, Chuanxin Huang, Yasodha Natkunam, Shruti Bhatt, Xiaoqing Lu, Xiaoyu Jiang, Isabel Romero-Camarero, Aharon Freud, Shuchun Zhao, Carlos E. Bacchi, Jose A. Martínez-Climent, Isidro Sánchez-García, Ari Melnick, Izidore S. Lossos

Blood (2012) 119 (23): 5478–5491.

https://doi.org/10.1182/blood-2012-01-403154

Published: 2012

Includes: Supplemental data

Journal Articles

Homeobox NKX2-3 Is Over-Expressed in Human B-Cell Lymphomas and Drives Marginal Zone B-Cell Lymphomagenesis in Mice

Eloy F Robles, PhD, Beatriz Aldaz, MSc, Takashi Akasaka, MD, PhD, Laura Macri Pellizzeri, MSc, Eduardo Martinez-Anso, PhD, Xavier Aguirre, PhD, Felipe Prosper, MD, Idoia Martin-Guerrero, PhD, Victor Segura, PhD, Maria José Calasanz, PhD, Isidro Sanchez-Garcia, MD, Elena Campos-Sanchez, MSc, Cesar Cobaleda, PhD, Charlotte Cresson, MSc, Cyril Broccardo, PhD, Reiner Siebert, Prof., Dr. med., Xabier Sagaert, MD, Martin JS Dyer, MA, DPhil, FRCP, FRCPath, Jose A Martinez-Climent, MD, PhD

Blood (2011) 118 (21): 260.

https://doi.org/10.1182/blood.V118.21.260.260

Published: 2011

Journal Articles

HGAL-a Germinal Center Specific Protein, Enhances B-Cell Receptor Signaling by Activation of Syk, Leading to Follicular Lymphoproliferation

Xiaoyu Jiang, PhD, Isabel Romero-Camarero, Ph.D, Xiaoqing Lu, M.D, Carolina Vicente-Dueñas, Ines Gonzalez-Herrero, Teresa Flores, Juan Luis Garcia, George McNamara, Ph.D, Christian Kunder, Yasodha Natkunam, MD, PhD, Victor Segura, PhD, Lorenna Fontan-Gabas, Jose A Martinez-Climent, MD, PhD, Ash A Alizadeh, MD/PhD, Cesar Cobaleda, PhD, Isidro Sanchez-Garcia, MD, Izidore S Lossos, MD

Blood (2011) 118 (21): 584.

https://doi.org/10.1182/blood.V118.21.584.584

Published: 2011

Journal Articles

Identification of LMO2 Transcriptome and Interactome in Diffuse Large B-Cell Lymphoma by Integrated Experimental and Computational Approach

Elena Cubedo, PhD, Andrew J. Gentles, Ph.D., Chuanxin Huang, PhD, Yasodha Natkunam, MD, PhD, Shruti Bhatt, Xiaoyu Jiang, PhD, Xiaoqing Lu, M.D, Isabel Romero-Camarero, Ph.D, Sylvia K. Plevritis, Jose A Martinez-Climent, MD, PhD, Isidro Sanchez-Garcia, MD, Ari Melnick, MD, Izidore S Lossos, MD

Blood (2011) 118 (21): 438.

https://doi.org/10.1182/blood.V118.21.438.438

Published: 2011

Journal Articles

LITAF , a BCL6 Target Gene, Regulates Autophagia in B Cells and Is Essential for T-Cell Dependent Humoral Responses

Cristina Bertolo, PhD, Raquel Malumbres, PhD, Ainara Sagardoy, PhD, Eloy F Robles, PhD, Jose I Martinez-Ferrandis, PhD, Sergio Roa, PhD, Izidore S Lossos, MD, Xavier Sagaert, MD PhD, Ari Melnick, MD, Salomon Amar, MD, Jose A Martinez-Climent, MD, PhD

Blood (2011) 118 (21): 1391.

https://doi.org/10.1182/blood.V118.21.1391.1391

Published: 2011

Journal Articles

Preclinical Activity of LBH589 Alone or in Combination with Chemotherapy in a Xenogeneic Mouse Model of Human Acute Lymphoblastic Leukemia

Xabier Agirre, PhD, Amaia Vilas-Zornoza, PhD, Gloria Abizanda, Cristina Moreno, Victor Segura, PhD, Alba De Martino Rodriguez, Edurne San José-Enériz, Estíbaliz Miranda, José Ignacio Martín-Subero, Leire Garate, María J. Blanco-Prieto, José A. García de Jalón, Jose J. Rifon, MD, Jose A Martinez-Climent, MD, PhD, Juan Cruz Cigudosa, José Román-Gómez, Maria José Calasanz, PhD, Josep-Maria Ribera, MD, PhD, Felipe Prosper, MD

Blood (2011) 118 (21): 1520.

https://doi.org/10.1182/blood.V118.21.1520.1520

Published: 2011

Journal Articles

PIM2 inhibition as a rational therapeutic approach in B-cell lymphoma

Cristina Gómez-Abad, Helena Pisonero, Carmen Blanco-Aparicio, Giovanna Roncador, Alberto González-Menchén, Jose A. Martinez-Climent, Eva Mata, María Elena Rodríguez, Guillermo Muñoz-González, Margarita Sánchez-Beato, Juan F. Leal, James R. Bischoff, Miguel A. Piris

Blood (2011) 118 (20): 5517–5527.

https://doi.org/10.1182/blood-2011-03-344374

Published: 2011

Includes: Supplemental data

Journal Articles

NIK Is Involved In the Activation of the Classical and Alternative NF-κB Pathways In Diffuse Large B Cell Lymphoma

Lina Odqvist, Margarita Sánchez-Beato, Santiago Montes-Moreno, MD, Ken H Young, MD, Francesco Acquadro, Juan Cigudosa, PhD, Jose A Martinez-Climent, MD, PhD, Anabel Sáez, Lydia Sánchez, Miguel A. Piris, MD

Blood (2010) 116 (21): 3099.

https://doi.org/10.1182/blood.V116.21.3099.3099

Published: 2010

Journal Articles

A Novel Pro-Survival Function of Cyclin-D1 Underlies Its Oncogenic Role and Potential as a Therapeutic Target In Mantle Cell Lymphoma

Elena Beltran, PhD, Vicente Fresquet, PhD, Javier Martinez-Useros, Jose A. Richter-Larrea, PhD, Ainara Sagardoy, PhD, Izaskun Sesma, Luciana L. Almada, PhD, Santiago Montes-Moreno, MD, Stefan Gesk, MD, Reiner Siebert, Prof., Dr., med., MaJose Calasanz, PhD, Felipe Prosper, MD, Miguel A. Piris, MD, Martin E. Fernandez-Zapico, MD, Jose A Martinez-Climent, MD, PhD

Blood (2010) 116 (21): 769.

https://doi.org/10.1182/blood.V116.21.769.769

Published: 2010

NARROW

Deciphering the Immune Microenvironment in Waldenstrom's Macroglobulinemia

Remodeling of the Immune Microenvironment By Oncogenic MYD88 Dictates Immunotherapy Responses across Indolent and Aggressive B-Cell Lymphomas

Lymphoma-Derived IL-10 Is a Key Immunomodulatory Factor at the Tumor Microenvironment of Activated B-Cell Diffuse Large B-Cell Lymphoma and Influences In Vivo Responses to Immunotherapy

Targeting the immune microenvironment in Waldenström macroglobulinemia via halting the CD40/CD40-ligand axis

Activation of the PP2A-B56α heterocomplex synergizes with venetoclax therapies in AML through BCL2 and MCL1 modulation

Immune Biomarkers of Survival and Severe Infection in Newly Diagnosed Multiple Myeloma (NDMM) Patients (pts) Treated with the Backbone Regimen Lenalidomide and Dexamethasone (Rd)

DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features

Inhibition of the Methyltransferase G9a with Small Molecules As a New Therapeutic Strategy for Treatment of Hematological Malignancies

Acquired mutations in BCL2 family proteins conferring resistance to the BH3 mimetic ABT-199 in lymphoma

Genome-Wide Promoter Methylation Profiling Of Splenic Marginal Zone Lymphoma (SMZL) Identifies Two Subgroups Of Patients With Distinct Genetic and Biologic Features and Different Outcomes

Downregulation of FOXP1 is required during germinal center B-cell function

Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma

Homeobox NKX2-3 Is Over-Expressed in Human B-Cell Lymphomas and Drives Marginal Zone B-Cell Lymphomagenesis in Mice

HGAL-a Germinal Center Specific Protein, Enhances B-Cell Receptor Signaling by Activation of Syk, Leading to Follicular Lymphoproliferation

Identification of LMO2 Transcriptome and Interactome in Diffuse Large B-Cell Lymphoma by Integrated Experimental and Computational Approach

LITAF , a BCL6 Target Gene, Regulates Autophagia in B Cells and Is Essential for T-Cell Dependent Humoral Responses

Preclinical Activity of LBH589 Alone or in Combination with Chemotherapy in a Xenogeneic Mouse Model of Human Acute Lymphoblastic Leukemia

PIM2 inhibition as a rational therapeutic approach in B-cell lymphoma

NIK Is Involved In the Activation of the Classical and Alternative NF-κB Pathways In Diffuse Large B Cell Lymphoma

A Novel Pro-Survival Function of Cyclin-D1 Underlies Its Oncogenic Role and Potential as a Therapeutic Target In Mantle Cell Lymphoma

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American Society of Hematology

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American Society of Hematology

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