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Sergio Roa
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Journal Articles

Lymphoma-Derived IL-10 Is a Key Immunomodulatory Factor at the Tumor Microenvironment of Activated B-Cell Diffuse Large B-Cell Lymphoma and Influences In Vivo Responses to Immunotherapy

Marcos Garcia-Lacarte, Sara C Grijalba, Francisco J Novo, Adrián Arnaiz-Leché, Javier Melchor, Marién Pascual, Enrique Goñi, Sandra Morales-Sánchez, María A Burrell, Oscar Blanco, Iñigo Clemente-Larramendi, Jose A Martinez-Climent, Noelia Casares, Juan J Lasarte, Pablo Sarobe, Miguel Canales, Sergio Roa
Journal: Blood
Blood (2023) 142 (Supplement 1): 716.
https://doi.org/10.1182/blood-2023-177612
Published: 2023
Journal Articles

Remodeling of the Immune Microenvironment By Oncogenic MYD88 Dictates Immunotherapy Responses across Indolent and Aggressive B-Cell Lymphomas

Jon Celay, Miriam Recalde, María Victoria Revuelta, Marta Larrayoz, Sara Rodriguez, Maria J Garcia-Barchino, Jennifer R. Chapman-Fredricks, Teresa Lozano, Juan J Lasarte, Ming Q. Du, Izidore S. Lossos, Sergio Roa, Aldo Roccaro, Miguel Canales, Felipe Prosper, Bruno Paiva, Leandro Cerchietti, Jose A. Martinez-Climent
Journal: Blood
Blood (2023) 142 (Supplement 1): 431.
https://doi.org/10.1182/blood-2023-173394
Published: 2023
Journal Articles

PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas

Marién Pascual, María Mena-Varas, Eloy Francisco Robles, Maria-Jose Garcia-Barchino, Carlos Panizo, Sandra Hervas-Stubbs, Diego Alignani, Ainara Sagardoy, Jose Ignacio Martinez-Ferrandis, Karen L. Bunting, Stephen Meier, Xavier Sagaert, Davide Bagnara, Elizabeth Guruceaga, Oscar Blanco, Jon Celay, Alvaro Martínez-Baztan, Noelia Casares, Juan José Lasarte, Thomas MacCarthy, Ari Melnick, Jose Angel Martinez-Climent, Sergio Roa
Journal: Blood
Blood (2019) 133 (22): 2401–2412.
https://doi.org/10.1182/blood.2018889931
Published: 2019
Includes: Supplemental data
Journal Articles

miR-28 regulates the germinal center reaction and blocks tumor growth in preclinical models of non-Hodgkin lymphoma

Nahikari Bartolomé-Izquierdo, Virginia G. de Yébenes, Angel F. Álvarez-Prado, Sonia M. Mur, Juan A. Lopez del Olmo, Sergio Roa, Jesus Vazquez, Almudena R. Ramiro
Journal: Blood
Blood (2017) 129 (17): 2408–2419.
https://doi.org/10.1182/blood-2016-08-731166
Published: 2017
Includes: Supplemental data
Journal Articles

Inhibition of the Methyltransferase G9a with Small Molecules As a New Therapeutic Strategy for Treatment of Hematological Malignancies

Edurne San José-Enériz, PhD, Xabier Agirre, PhD, Obdulia Rabal, PhD, Sergio Roa, PhD, Amaia Vilas-Zornoza, PhD, Estíbaliz Miranda, Ana Ugarte, PhD, Juan Antonio Sanchez-Arias, PhD, Bruno Paiva, PhD, Jesus F. San Miguel, Jose A. Martinez-Climent, MD PhD, Julen Oyarzabal, PhD, Felipe Prosper, MD
Journal: Blood
Blood (2014) 124 (21): 3532.
https://doi.org/10.1182/blood.V124.21.3532.3532
Published: 2014
Journal Articles

Downregulation of FOXP1 is required during germinal center B-cell function

Ainara Sagardoy, Jose I. Martinez-Ferrandis, Sergio Roa, Karen L. Bunting, María Angela Aznar, Olivier Elemento, Rita Shaknovich, Lorena Fontán, Vicente Fresquet, Ignacio Perez-Roger, Eloy F. Robles, Linde De Smedt, Xavier Sagaert, Ari Melnick, Jose A. Martinez-Climent
Journal: Blood
Blood (2013) 121 (21): 4311–4320.
https://doi.org/10.1182/blood-2012-10-462846
Published: 2013
Includes: Supplemental data
Journal Articles

IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions

Piers E. M. Patten, Charles C. Chu, Emilia Albesiano, Rajendra N. Damle, Xiao-Jie Yan, Dorothy Kim, Lu Zhang, Amanda R. Magli, Jacqueline Barrientos, Jonathan E. Kolitz, Steven L. Allen, Kanti R. Rai, Sergio Roa, Patricia K. Mongini, Thomas MacCarthy, Matthew D. Scharff, Nicholas Chiorazzi
Journal: Blood
Blood (2012) 120 (24): 4802–4811.
https://doi.org/10.1182/blood-2012-08-449744
Published: 2012
Includes: Supplemental data
Journal Articles

LITAF , a BCL6 Target Gene, Regulates Autophagia in B Cells and Is Essential for T-Cell Dependent Humoral Responses

Cristina Bertolo, PhD, Raquel Malumbres, PhD, Ainara Sagardoy, PhD, Eloy F Robles, PhD, Jose I Martinez-Ferrandis, PhD, Sergio Roa, PhD, Izidore S Lossos, MD, Xavier Sagaert, MD PhD, Ari Melnick, MD, Salomon Amar, MD, Jose A Martinez-Climent, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1391.
https://doi.org/10.1182/blood.V118.21.1391.1391
Published: 2011