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Journal Articles

Revumenib Monotherapy in Patients with Relapsed/Refractory KMT2Ar Acute Leukemia: Topline Efficacy and Safety Results from the Pivotal Augment-101 Phase 2 Study

Ibrahim Aldoss, Ghayas C. Issa, Michael Thirman, John DiPersio, Martha Arellano, James S. Blachly, Gabriel N. Mannis, Alexander Perl, David S. Dickens, Christine M. McMahon, Elie Traer, C. Michel Zwaan, Carolyn Grove, Richard Stone, Paul J. Shami, Ioannis Mantzaris, Matthew Greenwood, Neerav Shukla, Branko Cuglievan, Yu Gu, Rebecca G. Bagley, Kate Madigan, Soujanya Sunkaraneni, Huy Van Nguyen, Nicole McNeer, Eytan M. Stein
Journal: Blood
Blood (2023) 142 (Supplement 2): LBA-5.
https://doi.org/10.1182/blood-2023-192042
Published: 2023
Journal Articles

Reduced Intensity Haploidentical Bone Marrow Transplantation in Adults with Severe Sickle Cell Disease: BMT CTN 1507

Adetola A. Kassim, Mark C. Walters, Mary Eapen, Nicole Ritzau, Madoc Smith, Melhem M. Solh, Christopher McKinney, Michael Nieder, Maureen Ross, Michael Kent, Ghada Abusin, Kanwaldeep K. Mallhi, Jorge Galvez Silva, Paul Shaughnessy, Julie Kanter, Hilary Haines, Rafic J Farah, Yasser Khaled, Allistair Abraham, Catherine M. Bollard, Kenneth R. Cooke, Josu de La Fuente, Rabi Hanna, Mary M. Horowitz, Lori C Jordan, Lakshmanan Krishnamurti, Eric Leifere, Kris Michael Mahadeo, Shalini Shenoy, Nicole M. Ritzau, Michael R. DeBaun, Robert A. Brodsky
Journal: Blood
Blood (2023) 142 (Supplement 2): LBA-4.
https://doi.org/10.1182/blood-2023-192022
Published: 2023
Journal Articles

Phase 3 Randomized Study of Daratumumab (DARA) + Bortezomib, Lenalidomide, and Dexamethasone (VRd) Versus Vrd Alone in Patients (Pts) with Newly Diagnosed Multiple Myeloma (NDMM) Who Are Eligible for Autologous Stem Cell Transplantation (ASCT): Primary Results of the Perseus Trial

Pieter Sonneveld, Meletios A. Dimopoulos, Mario Boccadoro, Hang Quach, P. Joy Ho, Meral Beksac, Cyrille Hulin, Elisabetta Antonioli, Xavier Leleu, Silvia Mangiacavalli, Aurore Perrot, Michele Cavo, Angelo Belotti, Annemiek Broijl, Francesca Gay, Roberto Mina, Inger S. Nijhof, Niels W.C.J van de Donk, Eirini Katodritou, Fredrik Schjesvold, Anna Sureda Balari, Laura Rosiñol, Michel Delforge, Wilfried Roeloffzen, Tobias Silzle, Annette Vangsted, Hermann Einsele, Andrew Spencer, Roman Hajek, Artur Jurczyszyn, Sarah Lonergan, Tahamtan Ahmadi, Yanfang Liu, Jianping Wang, Diego Vieyra, Emilie M.J. van Brummelen, Veronique Vanquickelberghe, Anna Sitthi-Amorn, Carla J. de Boer, Robin Carson, Paula Rodríguez Otero, Joan Bladé, Philippe Moreau
Journal: Blood
Blood (2023) 142 (Supplement 2): LBA-1.
https://doi.org/10.1182/blood-2023-191911
Published: 2023
Journal Articles

PATH-HHT, a Double-Blind, Randomized, Placebo-Controlled Trial in Hereditary Hemorrhagic Telangiectasia Demonstrates That Pomalidomide Reduces Epistaxis and Improves Quality of Life

Hanny Al-Samkari, Raj S. Kasthuri, Vivek Iyer, Allyson M Pishko, Jake E Decker, Kevin J Whitehead, Miles B Conrad, Clifford Weiss, Joseph Parambil, Marc Stuart Zumberg, Jenny Y Zhou, Holly C Boyer, Vernon R Sutton, Marshall Mazepa, Lauren Bradley, Marianne S. Clancy, Lisa Wisniewski, Benjamin Carper, Diane Catellier, Sonia M Thomas, Keith R. McCrae
Journal: Blood
Blood (2023) 142 (Supplement 2): LBA-3.
https://doi.org/10.1182/blood-2023-191983
Published: 2023
Journal Articles

ERG Is a New Predisposition Gene for Bone Marrow Failure and Hematological Malignancy

Hamish S Scott, Jiarna Zerella, Claire Homan, Peer Arts, Steve Lin, Sam J Spinelli, Milena Babic, Peter J Brautigan, Lynda Truong, Luis Arriola-Martinez, Parvathy Venugopal, Simone K Feurstein, Lise Larcher, Flore Sicre De Fontbrune, Serwet Demirdas, Sonja De Munnik, Hélène Poirel, Benedicte Brichard, Sara Dobbins, Pim Mutsaers, Desiree S DeMille, Josue Flores-Daboub, Michael W Drazer, Alison Crawford, Julie McCarrier, Donald G Basel, Kerry Phillips, Nicola K Poplawski, Graeme Birdsey, Daniela Pirri, Pia Ostergaard, Annet Simons, Lucy Godley, David M. Ross, Devendra Hiwase, Jean Soulier, Anna Brown, Catherine Carmichael, Christopher N. Hahn
Journal: Blood
Blood (2023) 142 (Supplement 2): LBA-6.
https://doi.org/10.1182/blood-2023-191986
Published: 2023
Journal Articles

Ibrutinib Combined with Venetoclax in Patients with Relapsed/Refractory Mantle Cell Lymphoma: Primary Analysis Results from the Randomized Phase 3 Sympatico Study

Michael Wang, Wojciech Jurczak, Marek Trněný, David Belada, Tomasz Wrobel, Nilanjan Ghosh, Mary-Margaret Keating, Tom van Meerten, Ruben Fernandez Alvarez, Gottfried von Keudell, Catherine Thieblemont, Frederic Peyrade, Marc Andre, Marc Hoffmann, Edith Szafer Glusman, Jennifer Lin, James P. Dean, Jutta K. Neuenburg, Constantine S. Tam
Journal: Blood
Blood (2023) 142 (Supplement 2): LBA-2.
https://doi.org/10.1182/blood-2023-191921
Published: 2023
Journal Articles

Favezelimab in Combination with Pembrolizumab in Patients with Anti-PD-1-Naive Relapsed or Refractory Classical Hodgkin Lymphoma: Updated Analysis of an Open-Label Phase 1/2 Study

Nathalie A. Johnson, David Lavie, Peter Borchmann, Gareth P. Gregory, Alex F. Herrera, Leonard Minuk, Vladan Vucinic, Philippe Armand, Abraham Avigdor, Robin Gasiorowski, Yair Herishanu, Colm Keane, John Kuruvilla, Rachel Marceau West, Pallavi Pillai, Patricia Marinello, John Timmerman
Journal: Blood
Blood (2023) 142 (Supplement 1): 1693.
https://doi.org/10.1182/blood-2023-182128
Published: 2023
Journal Articles

Preclinical Studies of the GlyT1 Inhibitor Bitopertin in Diamond-Blackfan Anemia

Raymond T. Doty, Adam D. Munday, Hannah Cottnair, Sarah E. Funk, Janis L. Abkowitz
Journal: Blood
Blood (2023) 142 (Supplement 1): 1355.
https://doi.org/10.1182/blood-2023-174293
Published: 2023
Journal Articles

Efficacy and Safety of Recombinant Thrombopoietin Combined with Immunosuppressive Therapy for Primary Treatment of Severe Aplastic Anemia: A Single-Center, Open-Label, Randomized, Clinical Trial

Wenrui Yang, Xin Zhao, Guangxin Peng, Huihui Fan, Kang Zhou, Lei Ye, Jianping Li, Yuan Li, Liping Jing, Li Zhang, Fengkui Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1348.
https://doi.org/10.1182/blood-2023-179958
Published: 2023
Journal Articles

Senescence and Mitochondrial Transfer Ability of Bone Marrow Mesenchymal Stromal Cells Influence Patterns of Alloreactivity after Allogeneic Hematopoietic Stem Cell Transplantation

Romain Perouf, Meriem Hadid, Alexandra Guelton, Naceur Charif, Cecile Pochon, Maud D'Aveni, Simona Pagliuca, Marie-Thérèse Rubio, Natalia De Isla
Journal: Blood
Blood (2023) 142 (Supplement 1): 1334.
https://doi.org/10.1182/blood-2023-189093
Published: 2023
Journal Articles

The Bone Marrow Is the Primary Site of Thrombopoiesis

Nathan Asquith, Estelle Carminita, Antonio Rodriguez-Romera, Daniela Freire, Virginia Camacho, Isabelle C. Becker, Kellie R. Machlus, Abdullah O Khan, Joseph E. Italiano
Journal: Blood
Blood (2023) 142 (Supplement 1): 5403.
https://doi.org/10.1182/blood-2023-190991
Published: 2023
Journal Articles

In Phase 2 and Phase 3 Trials, Broadening the Definition of Acute Vaso-Occlusive Pain to Include at Least One Episode of Pain Requiring Nsaids, Opioids, or Both Treatments at Home within 30 Days of a Physician Visit

Alejandro R. Gonzalez-Barreto, Jose A. Mejias, Michael R. DeBaun
Journal: Blood
Blood (2023) 142 (Supplement 1): 5333.
https://doi.org/10.1182/blood-2023-190306
Published: 2023
Journal Articles

The Role of Neighborhood Disadvantage, Systemic Inflammation, and Acute Chest Syndrome in Children with Sickle Cell Disease

Shaniqua Johnson Anum, Amal Rammah, Elaine Symanski, Jonathan M. Flanagan, Jahnavi Gollamudi
Journal: Blood
Blood (2023) 142 (Supplement 1): 5330.
https://doi.org/10.1182/blood-2023-190208
Published: 2023
Journal Articles

Large-Scale Characterization and Functional Assessment of Adaptive Immunity in Patients with MGUS and SMM Reveals Significant Defects

Michelle P. Aranha, Romanos Sklavenitis-Pistofidis, Yoshinobu Konishi, Ting Wu, Hong Yue, Elizabeth D. Lightbody, Mahshid Rahmat, Michael Timonian, Daniel L. Mallory, Michael P. Agius, Shohreh Varmeh, Nang Kham Su, Jacqueline Perry, Erica M. Horowitz, Maya Davis, Anna Justis, Radosław P. Nowak, Mark Hamilton, Daniel Auclair, Catherine R. Marinac, Eric Fischer, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 2548.
https://doi.org/10.1182/blood-2023-178062
Published: 2023
Journal Articles

Axatilimab Ameliorates Inflammation and Fibrosis By Targeting Macrophages in a Preclinical Model of Chronic GVHD

Anamika Bajpai, Linda Solomon, James Kearns, Angelina Volkova, Michael Pratta, Susan H. Smith
Journal: Blood
Blood (2023) 142 (Supplement 1): 2540.
https://doi.org/10.1182/blood-2023-181746
Published: 2023
Journal Articles

The Protective Role of Tubular Epithelial Cells Produced Fms-like Tyrosine Kinase Receptor 3 Ligand in Acute Kidney Injury

Na Li, Yao Guo, Zheqi Wen, Chuyu Xie, Mingcheng Huang, Jiang Shan, Yuming Zhao, Dengyang Zhang, Zhiguang Chang, Liuting Yu, Chi Kong Li, Zhihua Zheng, Zhizhuang Joe Zhao, Yun Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 2539.
https://doi.org/10.1182/blood-2023-174317
Published: 2023
Journal Articles

PD-1 Expression By Dendritic Cells Is a Key Regulator of T-Cell Immunity in Cancer

Rushil Shah, Konstantinos Aliazis, Anthos Christofides, Angelique A Pham, Rinku Pal, Vassiliki A Boussiotis
Journal: Blood
Blood (2023) 142 (Supplement 1): 2538.
https://doi.org/10.1182/blood-2023-178180
Published: 2023
Journal Articles

Patient, Caregiver, and Healthcare Provider Perspectives on Pharmacologic and Non-Pharmacologic Therapies for Pain in Sickle Cell Disease

Katie Parisio, Courtney Thomas, Elyse Andrews, Benjamin Bear, Alison Taggi Pinto, Corinna L. Schultz
Journal: Blood
Blood (2023) 142 (Supplement 1): 2321.
https://doi.org/10.1182/blood-2023-180120
Published: 2023
Journal Articles

Immune Profiling and Responses of Smoldering Multiple Myeloma Patients Treated in a Phase Ib Study of Pvx-410 Vaccine Targeting XBP1/CD138/CS1 Antigens, and Citarinostat, a Histone Deacetylase Inhibitor (HDACi) with and without Lenalidomide

Diana Cirstea, Rajib Shome, Joseph James Connolly, Emilie Duvallet, Amanda N. R. Joyce, Victor Moyo, Kathleen Lively, Gina Basinsky, Andrew J. Yee, Cristiana Costa Chase, Ehsan Malek, Ruben Niesvizky, Paul G. Richardson, Noopur S. Raje
Journal: Blood
Blood (2023) 142 (Supplement 1): 2017.
https://doi.org/10.1182/blood-2023-189332
Published: 2023
Journal Articles

Loss of SWI/SNF Complex Subunit Arid1a in B Cells Promotes Inflammation and Perturbs Germinal Center B Cell Responses

Ajay Abraham, Daniela Samaniego-Castruita, Jillian Paladino, Mi Thao Tran, Isabella Goeun Han, Prathyaya Ramesh, Heather Kligfeld, Rebecca Southern, Ashima Shukla, Vipul Shukla
Journal: Blood
Blood (2023) 142 (Supplement 1): 1400.
https://doi.org/10.1182/blood-2023-189789
Published: 2023