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Mary Ann Anderson
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Journal Articles

Venetoclax dose escalation rapidly activates a BAFF/BCL-2 survival axis in chronic lymphocytic leukemia

Meng-Xiao Luo, Tania Tan, Marie Trussart, Annika Poch, Thi Minh Hanh Nguyen, Terence P. Speed, Damien G. Hicks, Esther Bandala-Sanchez, Hongke Peng, Stéphane Chappaz, Charlotte Slade, Daniel T. Utzschneider, Rachel M. Koldej, David Ritchie, Andreas Strasser, Rachel Thijssen, Matthew E. Ritchie, Constantine S. Tam, Geoffrey J. Lindeman, David C. S. Huang, Thomas E. Lew, Mary Ann Anderson, Andrew W. Roberts, Charis E. Teh, Daniel H. D. Gray
Journal: Blood
Blood (2024) 144 (26): 2748–2761.
https://doi.org/10.1182/blood.2024024341
Published: 2024
Includes: Supplemental data
Journal Articles

Sonrotoclax and Zanubrutinib as Frontline Treatment for CLL Demonstrates High MRD Clearance Rates with Good Tolerability: Data from an Ongoing Phase 1/1b Study BGB-11417-101

Jacob D. Soumerai, Chan Y. Cheah, Mary Ann Anderson, Masa Lasica, Emma Verner, Stephen S. Opat, Shuo Ma, Robert Weinkove, Raul Cordoba, Paolo Ghia, Sophie Leitch, David Westerman, Sheel Patel, Yiqian Fang, Wei Ding, Haiyi Guo, Constantine S. Tam
Journal: Blood
Blood (2024) 144 (Supplement 1): 1012.
https://doi.org/10.1182/blood-2024-199175
Published: 2024
Journal Articles

Marginal Zone Lymphoma Is Associated with Dysregulated Peripheral Blood Immunity Which Is Not Changed By Ibrutinib-Venetoclax Treatment

Joanne Elizabeth Davis, Lina HH Le, Mandy Ludford-Menting, Nicholas Holzwart, Sasanka M Handunnetti, Constantine S. Tam, Mary Ann Anderson, David S. Ritchie, Rachel Koldej
Journal: Blood
Blood (2024) 144 (Supplement 1): 4384.
https://doi.org/10.1182/blood-2024-199866
Published: 2024
Journal Articles

Real-World Outcomes of Patients with High-Grade B-Cell Lymphoma with MYC and BCL2 rearrangements Treated in the Contemporary Era

Victor S. Lin, Sean Harrop, Sean J. McKeague, Rory Bennett, Adrian Minson, Divya V. Somasekharannair, Edward Chew, Cameron Snell, Stephen Lade, Philip A. Thompson, John F. Seymour, Michael J. Dickinson, Mary Ann Anderson
Journal: Blood
Blood (2024) 144 (Supplement 1): 1700.
https://doi.org/10.1182/blood-2024-207849
Published: 2024
Journal Articles

Cognitive and Psychological Recovery from the Immune Effector Cell Associated Neurotoxicity Syndrome Following Chimeric Antigen Receptor T-Cell (CAR-T) Therapy

Valeriya Kuznetsova, Harsh Oza, Hannah Rosenfeld, Carmela Sales, Sam van der Linde, Izanne Roos, Stefanie Roberts, Fiore D'Aprano, Samantha M. Loi, Mark R Dowling, Michael J. Dickinson, Tomas Kalincik, Simon J Harrison, Charles B. Malpas, Mary Ann Anderson
Journal: Blood
Blood (2024) 144 (Supplement 1): 7240.
https://doi.org/10.1182/blood-2024-202851
Published: 2024
Journal Articles

Bridging Radiotherapy to Axicabtagene Ciloleucel (axi-cel) Is Associated with Favourable Outcomes for Large B-Cell Lymphoma (LBCL) in Third-Line and Beyond: An Australian Single-Centre Real-World Experience

Hamish W Scott, Mark R Dowling, Daniel Garcia, Samantha van der Linde, Nicole O'Leary, Brydon Panozzo, Adrian Minson, James A Kuzich, Aaron Jun Ning Wong, Michael S Hofman, Monique Youl, Belinda Campbell, Michael Patrick Macmanus, Philip A. Thompson, Mary Ann Anderson, John F. Seymour, Michael J Dickinson, Simon J Harrison
Journal: Blood
Blood (2024) 144 (Supplement 1): 4511.
https://doi.org/10.1182/blood-2024-209767
Published: 2024
Journal Articles

Predicting Risk of Infection in Patients Receiving CAR-T for Aggressive Lymphoma: A Study Exploring the Utility of Immune Profiling

Gemma K Reynolds, Lewis Williams, Mary Ann Anderson, Mark R Dowling, Adrian Minson, Michael J. Dickinson, Karin A Thursky, Simon J Harrison, Monica A Slavin, Marcel Doerflinger, Benjamin W Teh
Journal: Blood
Blood (2024) 144 (Supplement 1): 7136.
https://doi.org/10.1182/blood-2024-203133
Published: 2024
Journal Articles

Longitudinal Cytokine Expression in Aggressive Lymphoma Patients Treated with CAR-T: Applications of Immune Profiling to CAR-T

Gemma K Reynolds, Lewis Williams, Mary Ann Anderson, Mark R Dowling, Adrian Minson, Michael J. Dickinson, Karin A Thursky, Simon J Harrison, Monica A Slavin, Marcel Doerflinger, Benjamin W Teh
Journal: Blood
Blood (2024) 144 (Supplement 1): 7135.
https://doi.org/10.1182/blood-2024-202836
Published: 2024
Journal Articles

Seven-year outcomes of venetoclax-ibrutinib therapy in mantle cell lymphoma: durable responses and treatment-free remissions

Clinical Trials & Observations Brief Report
Sasanka M. Handunnetti, Mary Ann Anderson, Kate Burbury, Philip A. Thompson, Glenda Burke, Mathias Bressel, Juliana Di Iulio, Rodney J. Hicks, David Westerman, Stephen Lade, Christiane Pott, Rishu Agarwal, Rachel Koldej, David Ritchie, Martin Dreyling, Mark A. Dawson, Sarah-Jane Dawson, John F. Seymour, Andrew W. Roberts, Constantine S. Tam
Journal: Blood
Blood (2024) 144 (8): 867–872.
https://doi.org/10.1182/blood.2023023388
Published: 2024
Includes: Supplemental data
Journal Articles

CAR T cells and time-limited ibrutinib as treatment for relapsed/refractory mantle cell lymphoma: the phase 2 TARMAC study

Clinical Trials & Observations
Adrian Minson, Nada Hamad, Chan Y. Cheah, Constantine Tam, Piers Blombery, David Westerman, David Ritchie, Huw Morgan, Nicholas Holzwart, Stephen Lade, Mary Ann Anderson, Amit Khot, John F. Seymour, Molly Robertson, Imogen Caldwell, Georgina Ryland, Javad Saghebi, Zahra Sabahi, Jing Xie, Rachel Koldej, Michael Dickinson
Journal: Blood
Blood (2024) 143 (8): 673–684.
https://doi.org/10.1182/blood.2023021306
Published: 2024
Includes: Supplemental data
Journal Articles

BAX Mutated Clonal Hematopoiesis Arises Following Treatment with the BCL2 Inhibitor Class of Therapeutics across a Range of Hematological and Non-Hematological Neoplasms

Ing Soo Tiong, Tamia Nguyen, Charis Teh, Chong Chyn Chua, Sarah Ftouni, Thomas E Lew, Fiona C. Brown, Donia Moujalled, Christine Muttiah, Daniel Gray, Mary Ann Anderson, Philip A. Thompson, Constantine S. Tam, John F. Seymour, Sarah-Jane Dawson, Andrew H. Wei, Geoffrey Lindeman, Piers Blombery
Journal: Blood
Blood (2023) 142 (Supplement 1): 2688.
https://doi.org/10.1182/blood-2023-180386
Published: 2023
Journal Articles

Infections in Lymphoma Patients Treated with Bispecific Therapies: A Systematic Review and Meta-Analysis

Gemma K Reynolds, Marsali Maclean, Benjamin Teh, Karin A Thursky, Monica A Slavin, Mary Ann Anderson, Eliza A Hawkes
Journal: Blood
Blood (2023) 142 (Supplement 1): 6896.
https://doi.org/10.1182/blood-2023-185138
Published: 2023
Journal Articles

Combination Treatment with Sonrotoclax (BGB-11417), a Second-Generation BCL2 Inhibitor, and Zanubrutinib, a Bruton Tyrosine Kinase (BTK) Inhibitor, Is Well Tolerated and Achieves Deep Responses in Patients with Treatment-Naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (TN-CLL/SLL): Data from an Ongoing Phase 1/2 Study

Constantine S. Tam, Mary Ann Anderson, Masa Lasica, Emma Verner, Stephen S. Opat, Shuo Ma, Robert Weinkove, Raul Cordoba, Jacob Soumerai, Paolo Ghia, Sophie Leitch, James Hilger, Yiqian Fang, David Simpson, Haiyi Guo, Chan Yoon Cheah
Journal: Blood
Blood (2023) 142 (Supplement 1): 327.
https://doi.org/10.1182/blood-2023-179541
Published: 2023
Journal Articles

Monotherapy with Second-Generation BCL2 Inhibitor Sonrotoclax (BGB-11417) Is Well Tolerated with High Response Rates in Patients with Relapsed/Refractory Marginal Zone Lymphoma: Data from an Ongoing Phase 1 Study

Alessandra Tedeschi, Chan Yoon Cheah, Stephen S. Opat, Emma Verner, Laura Magnano, Narendranath Epperla, James Hilger, Yiqian Fang, David Simpson, Haiyi Guo, Mary Ann Anderson
Journal: Blood
Blood (2023) 142 (Supplement 1): 3032.
https://doi.org/10.1182/blood-2023-178841
Published: 2023
Journal Articles

Depletion of the Mitochondrial E3 Ligase MARCH5 Induces Synthetic Lethality to BCL2 Inhibitor (Venetoclax) Therapy in Cell Lines Representative of Diverse Blood Cancers

Thomas E Lew, Mark Van Delft, Chris Riffkin, Georgiou Angela, Christine White, Yin Yuan, Jahja Michelle, Mary Ann Anderson, Rachel Thijssen, David C.S. Huang, Mark A Dawson, Andrew W. Roberts
Journal: Blood
Blood (2023) 142 (Supplement 1): 415.
https://doi.org/10.1182/blood-2023-184392
Published: 2023
Journal Articles

Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy

Rachel Thijssen, Luyi Tian, Mary Ann Anderson, Christoffer Flensburg, Andrew Jarratt, Alexandra L. Garnham, Jafar S. Jabbari, Hongke Peng, Thomas E. Lew, Charis E. Teh, Quentin Gouil, Angela Georgiou, Tania Tan, Tirta M. Djajawi, Constantine S. Tam, John F. Seymour, Piers Blombery, Daniel H.D. Gray, Ian J. Majewski, Matthew E. Ritchie, Andrew W. Roberts, David C.S. Huang
Journal: Blood
Blood (2022) 140 (20): 2127–2141.
https://doi.org/10.1182/blood.2022016040
Published: 2022
Includes: Supplemental data
Journal Articles

A Phase 1 Study with the Novel B-Cell Lymphoma 2 (Bcl-2) Inhibitor Bgb-11417 As Monotherapy or in Combination with Zanubrutinib (ZANU) in Patients (Pts) with CLL/SLL: Preliminary Data

Chan Y. Cheah, Constantine S. Tam, Masa Lasica, Emma Verner, Peter J. Browett, Mary Ann Anderson, James Hilger, Yiqian Fang, David Simpson, Stephen Opat
Journal: Blood
Blood (2022) 140 (Supplement 1): 2321–2323.
https://doi.org/10.1182/blood-2022-169662
Published: 2022
Journal Articles

Time-Limited Ibrutinib and Tisagenlecleucel Is Highly Effective in the Treatment of Patients with Relapsed or Refractory Mantle Cell Lymphoma, Including Those with TP53 Mutated and Btki-Refractory Disease: First Report of the Tarmac Study

Adrian Minson, Nada Hamad, Chan Y. Cheah, Constantine S. Tam, Piers Blombery, David A Westerman, Stephen Lade, David Ritchie, Rachel M Koldej, Mary Ann Anderson, Amit Khot, John F. Seymour, Molly Robertson, Imogen R Caldwell, Georgina L Ryland, Jing Xie, Huw Morgan, Michael Dickinson
Journal: Blood
Blood (2022) 140 (Supplement 1): 181–183.
https://doi.org/10.1182/blood-2022-160459
Published: 2022
Journal Articles

Shielding the Vulnerable: A Multicentre Australian Rollout of Evusheld to Patients with Chronic Lymphocytic Leukaemia (CLL-SHIELD)

Ashley Whitechurch, Rory Bennett, Shafqat Inam, Benjamin Hartog, Rebecca Blackwood, Shevon Fernando, Felanita Hutani, Hadley Bortz, Mitchel Lincoln, Dennis Carney, Andrew W Roberts, Mary Ann Anderson, Constantine S. Tam, John F. Seymour
Journal: Blood
Blood (2022) 140 (Supplement 1): 9911–9912.
https://doi.org/10.1182/blood-2022-165609
Published: 2022
Journal Articles

Clonal hematopoiesis, myeloid disorders and BAX -mutated myelopoiesis in patients receiving venetoclax for CLL

Clinical Trials & Observations
Piers Blombery, Thomas E. Lew, Michael A. Dengler, Ella R. Thompson, Victor S. Lin, Xiangting Chen, Tamia Nguyen, Ashish Panigrahi, Sasanka M. Handunnetti, Dennis A. Carney, David A. Westerman, Constantine S. Tam, Jerry M. Adams, Andrew H. Wei, David C. S. Huang, John F. Seymour, Andrew W. Roberts, Mary Ann Anderson
Journal: Blood
Blood (2022) 139 (8): 1198–1207.
https://doi.org/10.1182/blood.2021012775
Published: 2022
Includes: Supplemental data