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Journal Articles

Safety, tolerability and efficacy of mesutoclax to treat patients with myeloid malignancies

Free
Qian Jiang, Huafeng Wang, Xingli Zhao, Suning Chen, Shuo Ma, Di Zhu, Weige Wang, Renbin Zhao, Jie Jin
Journal: Blood
Blood (2025) 146 (Supplement 1): 3417.
https://doi.org/10.1182/blood-2025-3417
Published: 2025
Journal Articles

Pirtobrutinib in Relapsed/Refractory (R/R) Waldenström macroglobulinemia (WM): Up to 5 years of follow-up from the Phase 1/2 BRUIN study

Free
Chan Cheah, Manish Patel, Toby Eyre, Wojciech Jurczak, David Lewis, Thomas Gastinne, Shuo Ma, Jonathon Cohen, Krish Patel, Jennifer Brown, Lydia Scarfo, Talha Munir, Ewa Lech-Maranda, Marc Hoffmann, Chaitra Ujjani, Bita Fakhri, Michael Wang, Koji Izutsu, Hirokazu Nagai, Constantine Tam, Joanna Rhodes, Julie Vose, Matthew McKinney, James Gerson, Minal Barve, Bryone Kuss, Youngil Koh, Aisling Barrett, Steven Treon, Jorge Castillo, John Seymour, Amy Ruppert Stark, Samuel McNeely, Richard Walgren, Donald Tsai, Katherine Bao, Binoj Chandrasekharan Nair, Jennifer Woyach, Lia Palomba
Journal: Blood
Blood (2025) 146 (Supplement 1): 226.
https://doi.org/10.1182/blood-2025-226
Published: 2025
Journal Articles

Pirtobrutinib in post-cbtki CLL/SLL: Final update from the Phase 1/2 BRUIN study with more than 5 years follow-up

Free
William Wierda, Jennifer Brown, Paolo Ghia, Lindsey Roeker, Krish Patel, Toby Eyre, Talha Munir, Ewa Lech-Maranda, Nicole Lamanna, Constantine Tam, John Seymour, Benoit Tessoulin, Nirav Shah, Chaitra Ujjani, Bita Fakhri, Catherine Coombs, Ian Flinn, Manish Patel, Sunita Dwivedy Nasta, Jonathon Cohen, Alvaro Alencar, Chan Cheah, Shuo Ma, Joanna Rhodes, Deepa Jagadeesh, Pier Luigi Zinzani, Anders Österborg, Koji Izutsu, Noriko Fukuhara, Donald Tsai, Paolo Abada, Minna Balbas, Jian Li, Ying (denise) Wang, Wojciech Jurczak, Jennifer Woyach
Journal: Blood
Blood (2025) 146 (Supplement 1): 2115.
https://doi.org/10.1182/blood-2025-2115
Published: 2025
Journal Articles

Pirtobrutinib in Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL): Final update from the Phase 1/2 BRUIN study

Free
Michael Wang, Jonathon Cohen, Nirav Shah, Wojciech Jurczak, Pier Luigi Zinzani, Chan Cheah, Chaitra Ujjani, Youngil Koh, Won Seog Kim, Sunita Dwivedy Nasta, Ian Flinn, Benoit Tessoulin, Shuo Ma, Alvaro Alencar, David Lewis, Jennifer Woyach, Kami Maddocks, Krish Patel, Yucai Wang, Joanna Rhodes, Constantine Tam, John Seymour, Hirokazu Nagai, Julie Vose, Bita Fakhri, Marc Hoffmann, Francisco Hernandez-Ilizaliturri, Andrew Zelenetz, Anita Kumar, Talha Munir, Donald Tsai, Paolo Abada, Minna Balbas, Jian Li, Ying (denise) Wang, Lindsey Roeker, Toby Eyre
Journal: Blood
Blood (2025) 146 (Supplement 1): 665.
https://doi.org/10.1182/blood-2025-665
Published: 2025
Journal Articles

Impact of sequencing of CART vs bi-specific antibody on survival in relapsed/refractory large B-cell lymphoma: An analysis from the ABC consortium

Free
Max Kelsten, Colin Thomas, Yun Kyoung Tiger, Ari Pelcovits, Adam Kidwell, Matthew Cortese, James Davis, Deborah Stephens, Tamara Moyo, Lindsey Fitzgerald, Jonathon Cohen, Megan Melody, Vaishalee Kenkre, Brian Hess, Megan Herr, Geoffrey Shouse, Thomas Ollila, Daniel Antonio, Alexandra Noveihed, Omar Elghawy, Alan Kerr, Jonathan Moreira, Shuo Ma, Jane Winter, Nirav Shah, Leo Gordon, Narendranath Epperla, Natalie Grover, Reem Karmali
Journal: Blood
Blood (2025) 146 (Supplement 1): 398.
https://doi.org/10.1182/blood-2025-398
Published: 2025
Journal Articles

Preliminary safety and efficacy of boven (Zanubrutinib, Obinutuzumab, and Venetoclax) as frontline therapy for older patients with Mantle Cell Lymphoma

Free
Anita Kumar, Jacob Soumerai, Reem Karmali, Jeremy Abramson, Jeffrey Barnes, Bernadette Beatty, Jason Brecher, Philip Caron, Kenneth Carson, Maria Chabowska, Madelyn Coogan, Jayne Coyle, Kevin David, Meemanage De Zoysa, Ahmet Dogan, Zachary Epstein-Peterson, Paola Ghione, Cameron Gordan, Leo Gordon, Julie Haydu, Ephraim Hochberg, Patrick Connor Johnson, Ashlee Joseph, Akshata Kakolu, Alyssa Labarre, Carissa Laudati, Jennifer Lue, Shuo Ma, Rosalba Martignetti, Colette Owens, Olivia Maas, Joanna Mi, Rachel Nazzaro, James O'Grady, Jessica Pendleton, Gilles Salles, Venkatraman Seshan, Natalie Slupe, Pallawi Torka, Andrew Zelenetz
Journal: Blood
Blood (2025) 146 (Supplement 1): 888.
https://doi.org/10.1182/blood-2025-888
Published: 2025
Journal Articles

Docirbrutinib (AS-1763), a novel non-COVALENT pan-mutant BTK inhibitor, demonstrates durable clinical responses in patients with previously treated B-cell malignancies: Data from an ongoing Phase 1b study

Free
Nitin Jain, Catherine Coombs, James D'Olimpio, Nirav Shah, Jacqueline Barrientos, Seung Tae Lee, Danielle Brander, John Nemunaitis, Andrew Gillis-Smith, Shuo Ma, Shirou Kirita, Koji Yoshida, Masaaki Sawa, Kyoko Miyamoto, Akinori Arimura, William Wierda, Varsha Gandhi, Javier Pinilla-Ibarz
Journal: Blood
Blood (2025) 146 (Supplement 1): 3892.
https://doi.org/10.1182/blood-2025-3892
Published: 2025
Journal Articles

Frontline treatment of sonrotoclax (BGB-11417) and zanubrutinib for chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) demonstrates high undetectable minimal residual disease (uMRD) rates with favorable tolerability: Updated data from BGB-11417-101, an ongoing phase 1/1b study

Free
Constantine Tam, Mary Ann Anderson, Masa Lasica, Emma Verner, Stephen Opat, Shuo Ma, Robert Weinkove, Raul Cordoba, Jacob Soumerai, Paolo Ghia, Sophie Leitch, David Westerman, Sheel Patel, Yiqian Fang, James Hilger, Remus Vezan, Chan Cheah
Journal: Blood
Blood (2025) 146 (Supplement 1): 3891.
https://doi.org/10.1182/blood-2025-3891
Published: 2025
Journal Articles

Zanubrutinib + obinutuzumab + sonrotoclax in patients with treatment-naive chronic lymphocytic leukemia/small lymphocytic lymphoma (TN CLL/SLL): Initial results from an ongoing phase 1/1b study, BGB-11417-101

Free
Jacob Soumerai, Stephen Opat, Chan Cheah, Mazyar Shadman, Emma Verner, Monica Tani, Marc Hoffmann, Lori Leslie, Shuo Ma, Yiqian Fang, Gabriel Man, Binghao Wu, Charity Henrich, Sheel Patel, Remus Vezan, Constantine Tam
Journal: Blood
Blood (2025) 146 (Supplement 1): 3890.
https://doi.org/10.1182/blood-2025-3890
Published: 2025
Journal Articles

Bispecific antibody vs non-bispecific antibody systemic therapy as immediate next line treatment after chimeric antigen receptor T-cell (CART) failure in large B-cell lymphoma

Free
Kyle Miyazaki, Natalie Grover, Colin Thomas, Yun Kyoung Tiger, Ari Pelcovits, Matthew Cortese, James Davis, Adam Kidwell, Tamara Moyo, Lindsey Fitzgerald, Jonathon Cohen, Megan Melody, Vaishalee Kenkre, Megan Herr, Thomas Ollila, Geoffrey Shouse, Daniel Antonio, Deborah Stephens, Nirav Shah, Nour Nassour, Omar Elghawy, Jonathan Moreira, Adit Dharia, Salmaan Mubeen, Shuo Ma, Jane Winter, Leo Gordon, Brian Hess, Narendranath Epperla, Reem Karmali
Journal: Blood
Blood (2025) 146 (Supplement 1): 4502.
https://doi.org/10.1182/blood-2025-4502
Published: 2025
Journal Articles

Real-world outcomes with bispecific antibody therapies for aggressive B-cell lymphomas in octogenarians

Free
Lindsey Fitzgerald, Elena Nazarenko, Yizhe Xu, Natalie Grover, Colin Thomas, Yun Kyoung Tiger, Ari Pelcovits, Matthew Cortese, James Davis, Adam Kidwell, Tamara Moyo, Kyle Miyazaki, Jonathon Cohen, Megan Melody, Daniel Kerr, Vaishalee Kenkre, Thomas Ollila, Megan Herr, Salmaan Mubeen, Geoffrey Shouse, Daniel Antonio, Deborah Stephens, Nirav Shah, Jonathan Moreira, Shuo Ma, Jane Winter, Leo Gordon, Brian Hess, Reem Karmali, Narendranath Epperla
Journal: Blood
Blood (2025) 146 (Supplement 1): 3746.
https://doi.org/10.1182/blood-2025-3746
Published: 2025
Journal Articles

Zanubrutinib + venetoclax for treatment-naive chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), including patients with del(17p) and/or TP53 mutation and unmutated immunoglobulin heavy-chain variable status: 3-year results from SEQUOIA arm D

Free
Mazyar Shadman, Talha Munir, Shuo Ma, Masa Lasica, Monica Tani, Tadeusz Robak, Ian Flinn, Jennifer R. Brown, Paolo Ghia, Emmanuelle Ferrant, Constantine Tam, Wojciech Janowski, Wojciech Jurczak, Linlin Xu, Tian Tian, Nataliya Kuptsova-Clarkson, Marcus Lefebure, Jamie Hirata, Alessandra Tedeschi
Journal: Blood
Blood (2025) 146 (Supplement 1): 5669.
https://doi.org/10.1182/blood-2025-5669
Published: 2025
Journal Articles

Real world comparison of commercial CAR T-cell constructs for the treatment of LBCL

Free
Megan Melody, Alan Kerr, Megan Herr, Adit Dharia, Nicole Altomare, Natalie Grover, Colin Thomas, Omar Elghawy, Yun Kyoung Tiger, Alexandra Noveihed, Ari Pelcovits, Thomas Ollila, Matthew Cortese, James Davis, Adam Kidwell, Tamara Moyo, Lindsey Fitzgerald, Jonathon Cohen, Nikesh Shah, David Swoboda, Vaishalee Kenkre, Geoffrey Shouse, Daniel Antonio, Deborah Stephens, Nirav Shah, Jonathan Moreira, Shuo Ma, Jane Winter, Leo Gordon, Narendranath Epperla, Reem Karmali, Brian Hess
Journal: Blood
Blood (2025) 146 (Supplement 1): 781.
https://doi.org/10.1182/blood-2025-781
Published: 2025
Journal Articles

Outcomes of patients with Relapsed/Refractory aggressive B-cell lymphoma receiving bispecific antibody therapy as monotherapy or in combination with targeted therapy

Free
Timothy Oh, Ari Pelcovits, Natalie Grover, Colin Thomas, Yun Kyoung Tiger, Matthew Cortese, James Davis, Adam Kidwell, Tamara Moyo, Lindsey Fitzgerald, Jonathon Cohen, Megan Melody, Nikesh Shah, Vaishalee Kenkre, Brian Hess, Thomas Ollila, Megan Herr, Geoffrey Shouse, Salmaan Mubeen, Omar Elghawy, Daniel Antonio, Daniel Kerr, Calvin Lee, Jonathan Moreira, Shuo Ma, Jane Winter, Nirav Shah, Leo Gordon, Narendranath Epperla, Deborah Stephens, Reem Karmali
Journal: Blood
Blood (2025) 146 (Supplement 1): 4551.
https://doi.org/10.1182/blood-2025-4551
Published: 2025
Journal Articles

Socioeconomic disadvantage, as measured by area deprivation index (ADI), impacts survival in patients with relapsed/refractory aggressive lymphoma treated with CART

Free
Daniel Antonio, Tarneka Manning, Natalie Grover, Colin Thomas, Ari Pelcovits, Matthew Cortese, James Davis, Tamara Moyo, Lindsey Fitzgerald, Jonathon Cohen, Vaishalee Kenkre, Megan Herr, Deborah Stephens, Geoffrey Shouse, Jonathan Moreira, Shuo Ma, Jane Winter, Leo Gordon, Brian Hess, Narendranath Epperla, Reem Karmali
Journal: Blood
Blood (2025) 146 (Supplement 1): 6281.
https://doi.org/10.1182/blood-2025-6281
Published: 2025
Journal Articles

MRD-guided therapy of sonrotoclax (BGB-11417) + obinutuzumab (O) in patients with treatment-naive CLL: Initial results from an ongoing phase 1/1b study, BGB-11417-101

Free
Marc Hoffmann, Shuo Ma, Herbert Eradat, Constantine Tam, Masa Lasica, Paul Hampel, Emma Verner, Lori Leslie, Christopher D'Angelo, Jacob Soumerai, Mazyar Shadman, Chan Cheah, Monica Tani, Yiqian Fang, Binghao Wu, Gabriel Man, Sheel Patel, Remus Vezan, Stephen Opat
Journal: Blood
Blood (2025) 146 (Supplement 1): 793.
https://doi.org/10.1182/blood-2025-793
Published: 2025
Journal Articles

Phase II, single-arm, open-label, multicenter study: Efficacy of adjunctive Bruton's tyrosine kinase inhibitor (BTKi) zanubrutinib and chimeric antigen receptor (CART) in aggressive B-cell non-hodgkins lymphoma (aNHL)

Free
Reem Karmali, Carlos Galvez, Jane Winter, Shuo Ma, Bin Zhang, Ping Xie, Yangruijue (Anna) Ma, Ruohui Chen, Nirav Shah, Leo Gordon
Journal: Blood
Blood (2025) 146 (Supplement 1): 1010.
https://doi.org/10.1182/blood-2025-1010
Published: 2025
Journal Articles

Risk factors for CRS and NT with bispecific antibodies: Data from the American bispecifics and CART (ABC) consortium

Free
Victoria Gill, Ari Pelcovits, Thomas Ollila, Lindsey Fitzgerald, Narendranath Epperla, Natalie Grover, Colin Thomas, Yun Kyoung Tiger, Alexandra Noveihed, Matthew Cortese, James Davis, Adam Kidwell, Tamara Moyo, Kyle Miyazaki, Jonathon Cohen, Megan Melody, Adit Dharia, Vaishalee Kenkre, Megan Herr, Geoffrey Shouse, Daniel Antonio, Deborah Stephens, Nirav Shah, Jonathan Moreira, Shuo Ma, Jane Winter, Leo Gordon, Brian Hess, Reem Karmali
Journal: Blood
Blood (2025) 146 (Supplement 1): 960.
https://doi.org/10.1182/blood-2025-960
Published: 2025
Journal Articles

Lisocabtagene Maraleucel (liso-cel) in Patients (pts) with Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL): Updated Follow-up of Transcend CLL 004

Free
Tanya Siddiqi, Jordan Gauthier, Saad S. Kenderian, Danielle M. Brander, Kathleen Dorritie, Jacob D. Soumerai, Peter A. Riedell, Nirav N. Shah, Rajneesh Nath, Charalambos Andreadis, Daniel A. Ermann, Shuo Ma, Tatyana Feldman, Scott R. Solomon, Stephen J. Schuster, Sherilyn A. Tuazon, Serena K. Perna, San-San Ou, Neha Rane, Eniko Papp, Yizhe Chen, William G. Wierda
Journal: Blood
Blood (2024) 144 (Supplement 1): 4633.
https://doi.org/10.1182/blood-2024-200840
Published: 2024
Journal Articles

Clinical Outcomes of Transformed Follicular Lymphoma with CAR T-Cell Therapy: A US Multicenter Real-World Analysis

Free
Matthew J. Cortese, MD, MPH, Megan M Herr, Nisha Nair, Jason Romancik, Natalie Grover, Rahul S Bhansali, Colin Thomas, Tamara K Moyo, Vaishalee P Kenkre, Thomas Ollila, Brian Hess, Lindsey Fitzgerald, Geoffrey Shouse, Matthew Matasar, Kaitlin Annunzio, James A Davis, Christy Jesme, Ari Pelcovits, Megan Melody, Jonathan Moreira, Adam Yuh Lin, Shuo Ma, Jane N Winter, Alex Niu, Alexey V. Danilov, Nirav N. Shah, Deborah M. Stephens, Jonathon B. Cohen, Leo I. Gordon, Stefan K. Barta, Narendranath Epperla, Reem Karmali
Journal: Blood
Blood (2024) 144 (Supplement 1): 525.
https://doi.org/10.1182/blood-2024-212106
Published: 2024