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Saad S. Kenderian
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Journal Articles

CD19 occupancy with tafasitamab increases therapeutic index of CART19 cell therapy and diminishes severity of CRS

R. Leo Sakemura, Claudia Manriquez Roman, Paulina Horvei, Elizabeth L. Siegler, James H. Girsch, Olivia L. Sirpilla, Carli M. Stewart, Kun Yun, Ismail Can, Ekene J. Ogbodo, Mohamad M. Adada, Evandro D. Bezerra, Lionel Aurelien Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Brooke L. Kimball, Long K. Mai, Truc N. Huynh, Wendy K. Nevala, Kristina Ilieva, Christian Augsberger, Maria Patra-Kneuer, Jürgen Schanzer, Jan Endell, Christina Heitmüller, Stefan Steidl, Sameer A. Parikh, Wei Ding, Neil E. Kay, Grzegorz S. Nowakowski, Saad S. Kenderian
Journal: Blood
Blood (2024) 143 (3): 258–271.
https://doi.org/10.1182/blood.2022018905
Published: 2024
Includes: Supplemental data
Journal Articles

Incidence of Richter Transformation in Patients with Chronic Lymphocytic Leukemia (CLL) /Small Lymphocytic Lymphoma (SLL): A Cohort Study Evaluating Different Therapeutic Eras

Paul J. Hampel, Kari G. Rabe, Yucai Wang, Steven R Hwang, Saad S. Kenderian, Eli Muchtar, Jose F. Leis, Amber Koehler, Mazie Tsang, Ricardo Parrondo, Rachel Bubik, Susan Marie Schwager, Curtis A. Hanson, Esteban Braggio, Susan L. Slager, Min Shi, Daniel L. Van Dyke, Timothy G. Call, Neil E. Kay, Wei Ding, Sameer A. Parikh
Journal: Blood
Blood (2023) 142 (Supplement 1): 3271.
https://doi.org/10.1182/blood-2023-185076
Published: 2023
Journal Articles

Outpatient Management of CAR-T and Teclistamab for Patients with Lymphoma and Multiple Myeloma

Radhika Bansal, Jonas Paludo, Andre Corraes, Megan Spychalla, Kelsey Haugen, Arushi Khurana, Paul J. Hampel, Urshila Durani, David Dingli, Suzanne R. Hayman, Prashant Kapoor, Yucai Wang, Moritz Binder, Saad S. Kenderian, Taxiarchis Kourelis, Shaji Kunnathu Kumar, Rahma M Warsame, N. Nora Bennani, Morie A. Gertz, Patrick B Johnston, Stephen M Ansell, Yi Lin
Journal: Blood
Blood (2023) 142 (Supplement 1): 253.
https://doi.org/10.1182/blood-2023-187186
Published: 2023
Journal Articles

Clinical Outcomes with Venetoclax-Based Treatment Regimens in Patients with Chronic Lymphocytic Leukemia (CLL)

Paul J. Hampel, Kari G. Rabe, Yucai Wang, Saad S. Kenderian, Wei Ding, Eli Muchtar, Jose F. Leis, Amber Koehler, Mazie Tsang, Ricardo Parrondo, Rachel Bubik, Susan Marie Schwager, Curtis A. Hanson, Esteban Braggio, Susan L. Slager, Min Shi, Daniel L. Van Dyke, Timothy G. Call, Neil E. Kay, Sameer A. Parikh
Journal: Blood
Blood (2023) 142 (Supplement 1): 3276.
https://doi.org/10.1182/blood-2023-183007
Published: 2023
Journal Articles

Outcomes of Patients with Small Lymphocytic Lymphoma (SLL) Receiving First Line Treatment

Samuel Kosydar, Kari G. Rabe, Yucai Wang, Saad S. Kenderian, Wei Ding, Eli Muchtar, Jose F. Leis, Amber Koehler, Mazie Tsang, Ricardo Parrondo, Talal Hilal, Rachel Bubik, Susan Marie Schwager, Curtis A. Hanson, Esteban Braggio, Susan L. Slager, Min Shi, Daniel L. Van Dyke, Timothy G. Call, Neil E. Kay, Sameer A. Parikh, Paul J Hampel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3284.
https://doi.org/10.1182/blood-2023-181866
Published: 2023
Journal Articles

PD-1 Expression in Lymphoma Cells Mediates Cellular Proliferation By Engaging Phosphatase SHP-1/SHP-2

Sutapa Sinha, Tammy Price-Troska, Shulan Tian, R. Leo Sakemura, Huihuang Yan, Justin Boysen, Zhiquan Wang, Xiaosheng Wu, Rong He, Min Shi, Yucai Wang, Eric W Klee, Sameer A. Parikh, Paul J Hampel, Timothy G. Call, Jose F. Leis, Tait D. Shanafelt, Stephen M Ansell, Saad S. Kenderian, Neil E. Kay, Wei Ding
Journal: Blood
Blood (2023) 142 (Supplement 1): 3261.
https://doi.org/10.1182/blood-2023-177755
Published: 2023
Journal Articles

Healthcare Utilization Outcomes of Outpatient CAR-T Cell Therapy with Remote Patient Monitoring Program

Jonas Paludo, Radhika Bansal, Matthew Hathcock, Joshua C Pritchett, Andre De Menezes Silva Corraes, Beatriz A Oyarzabal, William S Harmsen, Julianne J Lunde, Jordan D Coffey, Kelsey L Haugen, Megan Spychalla, Arushi Khurana, Hassan Alkhateeb, David Dingli, Suzanne R. Hayman, Prashant Kapoor, Morie A Gertz, Yucai Wang, Moritz Binder, Paul J. Hampel, Saad S. Kenderian, Taxiarchis Kourelis, Shaji Kunnathu Kumar, Mithun V Shah, Mustaqeem A Siddiqui, Rahma M Warsame, Jose. C. Villasboas, N. Nora Bennani, Patrick B Johnston, Stephen M Ansell, Tufia C Haddad, Yi Lin
Journal: Blood
Blood (2023) 142 (Supplement 1): 5075.
https://doi.org/10.1182/blood-2023-187834
Published: 2023
Journal Articles

Cytokine Release Syndrome Results in Reduced AML Killing By CD123 CAR T Cells

Anand S Bhagwat, Leonel Torres, Olga Shestova, Maksim Shestov, Noelle V. Frey, Elizabeth O Hexner, Selina M Luger, Alison W Loren, Mary Ellen Martin, Shannon R McCurdy, Alexander Perl, Edward A. Stadtmauer, James K. Mangan, Jennifer Brogdon, Joseph A Fraietta, Wei-Ting Hwang, Don L. Siegel, Saad S. Kenderian, David L. Porter, Carl June, Saar Gill
Journal: Blood
Blood (2023) 142 (Supplement 1): 217.
https://doi.org/10.1182/blood-2023-182104
Published: 2023
Journal Articles

Chronic Lymphoproliferative Disorder of Natural Killer Cells: Patient Characteristics, Laboratory Features, and Clinical Outcomes

Richard C. Godby, Kari G. Rabe, Steven R. Hwang, Hadiyah Audil, Susan L. Slager, Saad S. Kenderian, Neil E. Kay, Yucai Wang, Paul J Hampel, Sameer A. Parikh, Wei Ding, Min Shi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4446.
https://doi.org/10.1182/blood-2023-182545
Published: 2023
Journal Articles

Affinity of Anti-CD19 Antibodies Determines Subsequent CART19 Activation, Apoptosis and CRS in Preclinical Models

R. Leo Sakemura, Claudia Manriquez Roman, Long K. Mai, Brooke L. Kimball, Truc Huynh, Jennifer M. Feigin, James H. Girsch, Olivia L. Sirpilla, Kun Yun, Carli M. Stewart, Omar Gutierrez Ruiz, Ismail Can, Ekene Ogbodo, Lionel Aurelien Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Jan Jaehrling, Kristina Ilieva, Maria Patra-Kneuer, Christina Heitmüller, Stefan Steidl, Elizabeth L. Siegler, Saad S. Kenderian
Journal: Blood
Blood (2023) 142 (Supplement 1): 6796.
https://doi.org/10.1182/blood-2023-179408
Published: 2023
Journal Articles

Early Predictors of Severe Cytopenia Post CAR-T for Identification of Patients for Potential Stem Cell Collection

Andre De Menezes Silva Corraes, Radhika Bansal, Larissa Argenau Marques Brunaldi, Sikander Ailawadhi, Arushi Khurana, Paul J Hampel, Urshila Durani, David Dingli, Suzanne R. Hayman, Prashant Kapoor, Yucai Wang, Moritz Binder, Saad S. Kenderian, Taxiarchis Kourelis, Rahma M Warsame, N. Nora Bennani, Morie A. Gertz, Patrick B Johnston, Stephen M Ansell, Rafael Fonseca, P. Leif Bergsagel, Shaji Kunnathu Kumar, Ricardo Parrondo, Saurabh Chhabra, Yi Lin
Journal: Blood
Blood (2023) 142 (Supplement 1): 6927.
https://doi.org/10.1182/blood-2023-189683
Published: 2023
Journal Articles

Lisocabtagene Maraleucel (liso-cel) in R/R CLL/SLL: 24-Month Median Follow-up of TRANSCEND CLL 004

Tanya Siddiqi, David G Maloney, Saad S. Kenderian, Danielle M Brander, Kathleen Dorritie, Jacob Soumerai, Peter A Riedell, Nirav N. Shah, Rajneesh Nath, Bita Fakhri, Deborah M. Stephens, Shuo Ma, Tatyana Feldman, Scott R. Solomon, Stephen J. Schuster, Serena K. Perna, Sherilyn A. Tuazon, San-San Ou, Neha Rane, William G. Wierda
Journal: Blood
Blood (2023) 142 (Supplement 1): 330.
https://doi.org/10.1182/blood-2023-179529
Published: 2023
Journal Articles

Identification of IL-4 As a Key Regulator of CAR T-Cell Exhaustion Using Functional Genomics and Correlates of the Zuma-1 Clinical Trial

Carli M. Stewart, Michelle J. Cox, Reona Leo Sakemura, Ekene J. Ogbodo, Ismail Can, Claudia Manriquez-Roman, Kun Yun, Olivia Sirpilla, James H. Girsch, Truc Huynh, Elizabeth L. Siegler, Jenny J Kim, Mike Mattie, Nathalie Scholler, Simone Filosto, Saad S. Kenderian
Journal: Blood
Blood (2022) 140 (Supplement 1): 4536–4537.
https://doi.org/10.1182/blood-2022-160219
Published: 2022
Journal Articles

Treatment Patterns and Outcomes of Patients with Chronic Lymphocytic Leukemia with TP53 Mutations

Steven R Hwang, Yucai Wang, Kari G Rabe, Rong He, Saad S. Kenderian, Eli Muchtar, Paul J. Hampel, Neil E. Kay, Timothy G. Call, Amber Koehler, Amy L Behnken, Jose F. Leis, Esteban Braggio, Min Shi, David S. Viswanatha, Daniel L. Van Dyke, Susan L. Slager, Sameer A. Parikh, Wei Ding
Journal: Blood
Blood (2022) 140 (Supplement 1): 12390–12392.
https://doi.org/10.1182/blood-2022-165508
Published: 2022
Journal Articles

Comparison of Treatment-Emergent Adverse Events of Covalent BTK Inhibitors in Clinical Trials in B-Cell Malignancies: A Systematic Review and Meta-Analysis

Jacqueline F Wang, Steven R Hwang, Yi Jiang, Xinyue Qi, Shijia Zhang, Sameer A. Parikh, Wei Ding, Saad S. Kenderian, Eli Muchtar, Paul J. Hampel, Jose F. Leis, Javier L Munoz, Gita Thanarajasingam, Jonas Paludo, David J. Inwards, Grzegorz S. Nowakowski, Stephen M. Ansell, Thomas M. Habermann, Thomas E. Witzig, Neil E. Kay, Shouhao Zhou, Yucai Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 9882–9884.
https://doi.org/10.1182/blood-2022-168152
Published: 2022
Journal Articles

Immunosuppressive Monocyte Modulation of CAR T Cell Functions and Impact on Response to CART19

Kun Yun, Reona Leo Sakemura, Michelle J. Cox, Truc Huynh, Claudia Manriquez-Roman, Olivia Sirpilla, Carli M. Stewart, James H. Girsch, Ekene J. Ogbodo, Ismail Can, Brooke Kimball, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Elizabeth L. Siegler, Mike Mattie, Sao-Mai Nguyen-Mau, Simone Filosto, Saad S. Kenderian
Journal: Blood
Blood (2022) 140 (Supplement 1): 10263–10264.
https://doi.org/10.1182/blood-2022-164706
Published: 2022
Journal Articles

Chimeric Antigen Receptor Engineering of Mesenchymal Stromal Cells (CAR-MSC) Enhance Immunosuppression and Outcomes in Graft Versus Host Disease (GvHD) Preclinical Models

Olivia Sirpilla, Reona Leo Sakemura, Mehrdad Hefazi, James H. Girsch, Truc Huynh, Michelle J. Cox, Kendall J. Schick, Claudia Manriquez-Roman, Ismail Can, Kun Yun, Carli M. Stewart, Ekene J. Ogbodo, Elizabeth L. Siegler, Saad S. Kenderian
Journal: Blood
Blood (2022) 140 (Supplement 1): 1579–1580.
https://doi.org/10.1182/blood-2022-158872
Published: 2022
Journal Articles

Outpatient Practice Pattern for Recently Approved CAR-T in Patients with Lymphoma and Multiple Myeloma

Radhika Bansal, Jonas Paludo, Matthew A. Hathcock, Megan T Spychalla, Arushi Khurana, Paul J. Hampel, Urshila Durani, Hassan B. Alkhateeb, David Dingli, Suzanne R. Hayman, Prashant Kapoor, Yucai Wang, Saad S. Kenderian, Moritz Binder, Taxiarchis Kourelis, Shaji K Kumar, Mithun V. Shah, Rahma M Warsame, N. Nora Bennani, Morie A Gertz, Patrick B. Johnston, Stephen M. Ansell, Mustaqeem A. Siddiqui, Yi Lin
Journal: Blood
Blood (2022) 140 (Supplement 1): 2399–2401.
https://doi.org/10.1182/blood-2022-167187
Published: 2022
Journal Articles

Differential Susceptibility to Senescence in CART Cells Based on Co-Stimulatory Signaling

Ismail Can, Reona Leo Sakemura, Claudia Manriquez-Roman, Olivia Sirpilla, Carli M. Stewart, Kun Yun, Michelle J. Cox, Truc Huynh, James H. Girsch, Ekene J. Ogbodo, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Justin C. Boysen, Elizabeth L. Siegler, Atakan Ekiz, Saad S. Kenderian, Neil E. Kay
Journal: Blood
Blood (2022) 140 (Supplement 1): 8600–8601.
https://doi.org/10.1182/blood-2022-163446
Published: 2022
Journal Articles

CD19 Antigen Occupancy on Cancer Cells with the CD19 Monoclonal Antibody Tafasitamab Improves the Activation, Antitumor Efficacy, and Safety Profile of CART19 Cell Therapy

Reona Leo Sakemura, Claudia Manriquez-Roman, Paulina Horvei, Michelle J. Cox, Truc Huynh, James H. Girsch, Olivia Sirpilla, Kun Yun, Carli M. Stewart, Ismail Can, Ekene J. Ogbodo, Mohamad M. Adada, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Kristina Ilieva-Babinsky, Christian Augsberger, Maria Patra-Kneuer, Christina Heitmüller, Stefan Steidl, Sameer A. Parikh, Wei Ding, Neil E. Kay, Grzegorz S. Nowakowski, Elizabeth L. Siegler, Saad S. Kenderian
Journal: Blood
Blood (2022) 140 (Supplement 1): 2362–2364.
https://doi.org/10.1182/blood-2022-158273
Published: 2022