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David G Maloney
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Journal Articles

HA-1–targeted T-cell receptor T-cell therapy for recurrent leukemia after hematopoietic stem cell transplantation

Clinical Trials & Observations
Elizabeth F. Krakow, Michelle Brault, Corinne Summers, Tanya M. Cunningham, Melinda A. Biernacki, R. Graeme Black, Kyle B. Woodward, Nicole Vartanian, Sami B. Kanaan, Albert C. Yeh, Robson G. Dossa, Merav Bar, Ryan D. Cassaday, Ann Dahlberg, Brian G. Till, Andrew E. Denker, Cecilia C. S. Yeung, Ted A. Gooley, David G. Maloney, Stanley R. Riddell, Philip D. Greenberg, Aude G. Chapuis, Evan W. Newell, Scott N. Furlan, Marie Bleakley
Journal: Blood
Blood (2024) 144 (10): 1069–1082.
https://doi.org/10.1182/blood.2024024105
Published: 2024
Includes: Supplemental data
Journal Articles

Three-year follow-up analysis of axicabtagene ciloleucel in relapsed/refractory indolent non-Hodgkin lymphoma (ZUMA-5)

Clinical Trials & Observations
Sattva S. Neelapu, Julio C. Chavez, Alison R. Sehgal, Narendranath Epperla, Matthew Ulrickson, Emmanuel Bachy, Pashna N. Munshi, Carla Casulo, David G. Maloney, Sven de Vos, Ran Reshef, Lori A. Leslie, Olalekan O. Oluwole, Ibrahim Yakoub-Agha, Rashmi Khanal, Joseph Rosenblatt, Ronald Korn, Weixin Peng, Christine Lui, Jacob Wulff, Rhine Shen, Soumya Poddar, A. Scott Jung, Harry Miao, Sara Beygi, Caron A. Jacobson
Journal: Blood
Blood (2024) 143 (6): 496–506.
https://doi.org/10.1182/blood.2023021243
Published: 2024
Includes: Supplemental data
Journal Articles

Two-year follow-up of lisocabtagene maraleucel in relapsed or refractory large B-cell lymphoma in TRANSCEND NHL 001

Clinical Trials & Observations
Jeremy S. Abramson, M. Lia Palomba, Leo I. Gordon, Matthew Lunning, Michael Wang, Jon Arnason, Enkhtsetseg Purev, David G. Maloney, Charalambos Andreadis, Alison Sehgal, Scott R. Solomon, Nilanjan Ghosh, Christine Dehner, Yeonhee Kim, Ken Ogasawara, Ana Kostic, Tanya Siddiqi
Journal: Blood
Blood (2024) 143 (5): 404–416.
https://doi.org/10.1182/blood.2023020854
Published: 2024
Includes: Supplemental data
Journal Articles

Day +3/Day 0 Ferritin Ratio: A Simple Point-of-Care Index Predictive of Severe Immune Effector Cell-Associated Neurotoxicity Syndrome after CD19 CAR T-Cell Therapy

Jennifer J. Huang, Emily C Liang, Aya Albittar, Andrew J Portuguese, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Mazyar Shadman, Alexandre V Hirayama, Brian G Till, Erik L Kimble, Lorenzo Iovino, Aude G Chapuis, Folashade Otegbeye, Ryan D Cassaday, Filippo Milano, Cameron J. Turtle, David G Maloney, Jordan Gauthier
Journal: Blood
Blood (2023) 142 (Supplement 1): 3495.
https://doi.org/10.1182/blood-2023-182597
Published: 2023
Journal Articles

Machine Learning-Based Time-Series Clustering Identifies Archetypal Trajectories of Hematotoxicity after CAR T-Cell Therapy

Emily C Liang, Aya Albittar, Andrew J Portuguese, Jennifer J. Huang, Qian Wu, Joseph De Los Reyes, Nikki Pin, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Joshua A. Hill, Rahul Banerjee, Andrew J. Cowan, Damian J Green, Ajay K Gopal, Christina Poh, Mazyar Shadman, Alexandre V Hirayama, Brian G Till, Erik L Kimble, Lorenzo Iovino, Aude G Chapuis, Folashade Otegbeye, Ryan D Cassaday, Filippo Milano, David G Maloney, Jordan Gauthier
Journal: Blood
Blood (2023) 142 (Supplement 1): 2143.
https://doi.org/10.1182/blood-2023-174106
Published: 2023
Journal Articles

Phase I/II Study to Evaluate the Safety, Feasibility, and Efficacy of FP-1201 (Intravenous Interferon-Beta-1a) to Prevent Toxicities after CD19-Directed CAR T-Cell Therapy: Trial in Progress

Emily C Liang, Erik L Kimble, Aya Albittar, Jennifer J. Huang, Andrew J Portuguese, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Sylvain Simon, Tony Chour, Evan W. Newell, Rahul Banerjee, David G Maloney, Alexander Spicer, Juho Jalkanen, Alexandre V Hirayama, Jordan Gauthier
Journal: Blood
Blood (2023) 142 (Supplement 1): 4860.
https://doi.org/10.1182/blood-2023-173152
Published: 2023
Journal Articles

Intent to Treat Allogeneic Stem Cell Transplantation Outcomes in Relapsed/Refractory T-Cell Lymphomas

Christina Poh, Xinyi Fan, Jenna M Voutsinas, Qian Wu, Michi M Shinohara, Phuong T Vo, Mazyar Shadman, Chaitra S Ujjani, Ryan C Lynch, Brian G Till, Stephen D Smith, David G Maloney, Ajay K Gopal
Journal: Blood
Blood (2023) 142 (Supplement 1): 1708.
https://doi.org/10.1182/blood-2023-184314
Published: 2023
Journal Articles

Factors Associated with Prolonged CRS and Neurotoxicity after Treatment with Axicabtagene Ciloleucel

Aya Albittar, Jenna M Voutsinas, Andrew J Portuguese, Jennifer J. Huang, Emily C Liang, Qian Wu, Xinyi Fan, Alexandre V Hirayama, Erik L Kimble, Lorenzo Iovino, Christina Poh, Ajay K Gopal, Mazyar Shadman, Brian G Till, Filippo Milano, Aude G Chapuis, Ryan D Cassaday, David G Maloney, Jordan Gauthier
Journal: Blood
Blood (2023) 142 (Supplement 1): 2126.
https://doi.org/10.1182/blood-2023-180128
Published: 2023
Journal Articles

Acalabrutinib in Combination with Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy in Relapsed/Refractory B-Cell Lymphoma: A Phase I/II Study of Safety, Efficacy and Immune Correlative Analysis

Christina Poh, Victor A Chow, Ryan C Lynch, Chaitra S Ujjani, Mazyar Shadman, Brian G Till, Vikram Raghunathan, Edus H Warren, Jordan Gauthier, Stephen D Smith, Taran Gujral, Chihiro Morishima, Qian Wu, Jenna M Voutsinas, Amy Sperling, Joshua Dizon, David G Maloney, Ajay K Gopal
Journal: Blood
Blood (2023) 142 (Supplement 1): 2129.
https://doi.org/10.1182/blood-2023-183034
Published: 2023
Journal Articles

Clinical Outcomes in Patients Treated with Both Covalent Btkis and Venetoclax and the Significance of “Double-Refractory” Status in Patients with CLL/SLL

Laura Samples, Chaitra S Ujjani, Sirin Khajaviyan, Ryan C Lynch, Mehrdad Shakib-Azar, Christine Crider, Margie Fredericks, Stephanie Louie, Christina Poh, Stephen D Smith, Brian G Till, David G Maloney, Ajay K Gopal, Mazyar Shadman
Journal: Blood
Blood (2023) 142 (Supplement 1): 4650.
https://doi.org/10.1182/blood-2023-187129
Published: 2023
Journal Articles

Lisocabtagene Maraleucel Versus Axicabtagene Ciloleucel: Efficacy and Toxicity in a Real-World Setting

Andrew J Portuguese, Aya Albittar, Emily C Liang, Jennifer J. Huang, Alexandre V Hirayama, Erik L Kimble, Lorenzo Iovino, Christina Poh, Ajay K Gopal, Mazyar Shadman, Brian G Till, Hans-Peter Kiem, Filippo Milano, Aude G Chapuis, Folashade Otegbeye, Ryan D Cassaday, David G Maloney, Jordan Gauthier
Journal: Blood
Blood (2023) 142 (Supplement 1): 2131.
https://doi.org/10.1182/blood-2023-172978
Published: 2023
Journal Articles

Impact of “Cell-of-Origin” on Outcome after Axicabtagene-Ciloleucel CAR-T Cell Therapy in Relapsed/Refractory Aggressive Non-Hodgkin B-Cell Lymphomas

Ilaria Romano, Jordan Gauthier, Ryan C Lynch, Ajay K Gopal, Alexandre V Hirayama, Kikkeri N Naresh, Alireza Torabi, Stephen D Smith, Brian G Till, David G Maloney, Chaitra S Ujjani, Christina Poh, Filippo Milano, Aude G Chapuis, Mazyar Shadman, Lorenzo Iovino
Journal: Blood
Blood (2023) 142 (Supplement 1): 2137.
https://doi.org/10.1182/blood-2023-181956
Published: 2023
Journal Articles

Predictors of Outcomes with Venetoclax-Based Treatment in Patients with Progressive Disease or Intolerance after Covalent BTK Inhibitors

Laura Samples, Sirin Khajaviyan, Ryan C Lynch, Mehrdad Shakib-Azar, Christine Crider, Margie Fredericks, Hania Shakalia, Stephanie Louie, David G Maloney, Christina Poh, Brian G Till, Stephen D Smith, Ajay K Gopal, Chaitra S Ujjani, Mazyar Shadman
Journal: Blood
Blood (2023) 142 (Supplement 1): 4656.
https://doi.org/10.1182/blood-2023-186775
Published: 2023
Journal Articles

A Phase 2 Study of Nivolumab for Relapsed/Refractory Multiple Myeloma or Non-Hodgkin Lymphoma Following CAR-T Therapy

Rahul Banerjee, Ryan C Lynch, Qian Wu, Sylvain Simon, Chaitra S Ujjani, Brian G Till, Natalie Wuliji, Daria Gausman, Joshua Dizon, Mary L. Kwok, Sarah S. Lee, Rebecca Silbermann, Eva Medvedova, David G Maloney, Jorge Daniel Ramos, Mazyar Shadman, Jordan Gauthier, Cameron J. Turtle, Ajay K Gopal, Damian J Green, Stanley R. Riddell, Andrew J. Cowan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3509.
https://doi.org/10.1182/blood-2023-173202
Published: 2023
Journal Articles

Histone Methylation Mark Analyses Distinguish Carts Manufactured from Distinct Sources and Uncover Novel Transcription Factors Associated with In Vivo Function of Carts after Infusion into DLBCL Patients That Are Not Identified By RNA-Seq

Salvatore Fiorenza, Ye Zheng, Jay Sarthy, Alyssa Sheih, Erik L Kimble, Delaney Kirchmeier, Derek Janssens, Tinh-Doan Phi, Jordan Gauthier, Alexandre V Hirayama, Qian Wu, Raphael Gottardo, Stanley R. Riddell, David G Maloney, Steven Henikoff, Cameron J. Turtle
Journal: Blood
Blood (2023) 142 (Supplement 1): 3454.
https://doi.org/10.1182/blood-2023-188269
Published: 2023
Journal Articles

Lisocabtagene Maraleucel (liso-cel) in R/R CLL/SLL: 24-Month Median Follow-up of TRANSCEND CLL 004

Tanya Siddiqi, David G Maloney, Saad S. Kenderian, Danielle M Brander, Kathleen Dorritie, Jacob Soumerai, Peter A Riedell, Nirav N. Shah, Rajneesh Nath, Bita Fakhri, Deborah M. Stephens, Shuo Ma, Tatyana Feldman, Scott R. Solomon, Stephen J. Schuster, Serena K. Perna, Sherilyn A. Tuazon, San-San Ou, Neha Rane, William G. Wierda
Journal: Blood
Blood (2023) 142 (Supplement 1): 330.
https://doi.org/10.1182/blood-2023-179529
Published: 2023
Journal Articles

Axicabtagene Ciloleucel (Axi-Cel) in Patients with Relapsed/Refractory Indolent Non-Hodgkin Lymphoma: 4-Year Follow-up from the Phase 2 ZUMA-5 Trial

Sattva S. Neelapu, Julio C. Chavez, Alison R Sehgal, Narendranath Epperla, Matthew L. Ulrickson, Emmanuel Bachy, Pashna N. Munshi, Carla Casulo, David G Maloney, Sven de Vos, Ran Reshef, Lori A. Leslie, Olalekan O. Oluwole, Ibrahim Yakoub-Agha, Rashmi Khanal, Joseph D. Rosenblatt, Weixin Peng, Christine Lui, Jacob Wulff, Rhine R. Shen, Soumya Poddar, Andrew Lee, Harry Miao, Olga Nikolajeva, Caron A. Jacobson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4868.
https://doi.org/10.1182/blood-2023-174914
Published: 2023
Journal Articles

Phase 2 Study of Anakinra to Prevent CRS and Neurotoxicity after Treatment with Lisocabtagene Maraleucel: Planned Interim Analysis

Emily C Liang, Aya Albittar, Andrew J Portuguese, Jennifer J. Huang, Qian Wu, Joseph De Los Reyes, Nikki Pin, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Sylvain Simon, Tony Chour, Evan W. Newell, Mazyar Shadman, Alexandre V Hirayama, Brian G Till, Erik L Kimble, Lorenzo Iovino, Aude G Chapuis, Folashade Otegbeye, Ryan D Cassaday, Filippo Milano, David G Maloney, Jordan Gauthier
Journal: Blood
Blood (2023) 142 (Supplement 1): 6848.
https://doi.org/10.1182/blood-2023-172695
Published: 2023
Journal Articles

Phase 2 Study of CD19 CAR T Cells with a Fully Human Binder for Large B-Cell Lymphoma in Relapse or Progression after a Murine Binder-Bearing CD19 CAR T-Cell Therapy

Jordan Gauthier, Jennifer J. Huang, Carla Jaeger-Ruckstuhl, Emily C Liang, Aya Albittar, Andrew J Portuguese, Qian Wu, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Mazyar Shadman, Alexandre V Hirayama, Brian G Till, Erik L Kimble, Lorenzo Iovino, Aude G Chapuis, Folashade Otegbeye, Ryan D Cassaday, Filippo Milano, Christina Poh, Ajay K Gopal, Stanley R. Riddell, David G Maloney, Cameron J. Turtle
Journal: Blood
Blood (2023) 142 (Supplement 1): 6860.
https://doi.org/10.1182/blood-2023-181273
Published: 2023
Journal Articles

Phenotypic Analysis of Baseline T cell Subsets and Third Generation CD20 Targeted CAR T cell Products for Treatment of Relapsed/Refractory Follicular Lymphoma

George Mo, Sang Yun Lee, Jenna M Voutsinas, Qian Wu, Dong Hoon Lee, Jordan Gauthier, Alexandre V Hirayama, David G Maloney, Mazyar Shadman, Brian G Till
Journal: Blood
Blood (2023) 142 (Supplement 1): 6877.
https://doi.org/10.1182/blood-2023-180446
Published: 2023