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Caron A. Jacobson
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Journal Articles

Baseline Immune State and T-cell Clonal Kinetics are Associated with Durable Response to CAR-T Therapy in Large B-cell Lymphoma

Clinical Trials & Observations
Katie Maurer, Isabella N Grabski, Roch Houot, Satyen H. Gohil, Shogo Miura, Robert A Redd, Haoxiang Lyu, Wesley Lu, Yohei Arihara, Justin Budka, Mikaela McDonough, Michela Ansuinelli, Carol G Reynolds, Heather Jacene, Shuqiang Li, Kenneth J Livak, Jerome Ritz, Brodie Miles, Mike Mattie, Donna S. Neuberg, Rafael A. Irizarry, Philippe Armand, Catherine J Wu, Caron A. Jacobson
Journal: Blood
Blood blood.2024024381.
https://doi.org/10.1182/blood.2024024381
Published: 2024
Includes: Supplemental data
Journal Articles

Real-world and clinical trial outcomes in large B-cell lymphoma with axicabtagene ciloleucel across race and ethnicity

Clinical Trials & Observations
Frederick L. Locke, Tanya Siddiqi, Caron A. Jacobson, Armin Ghobadi, Sairah Ahmed, David B. Miklos, Miguel-Angel Perales, Javier Munoz, Warren B. Fingrut, Martina Pennisi, Jordan Gauthier, Mazyar Shadman, Lohith Gowda, Abu-Sayeef Mirza, Muhammad Bilal Abid, Sanghee Hong, Navneet S. Majhail, Mohamed A. Kharfan-Dabaja, Arushi Khurana, Talha Badar, Yi Lin, N. Nora Bennani, Megan M. Herr, Zhen-Huan Hu, Hai-Lin Wang, Anjani Baer, Elande Baro, Harry Miao, Clare Spooner, Hairong Xu, Marcelo C. Pasquini
Journal: Blood
Blood (2024) 143 (26): 2722–2734.
https://doi.org/10.1182/blood.2023023447
Published: 2024
Includes: Supplemental data
Journal Articles

Three-year follow-up analysis of axicabtagene ciloleucel in relapsed/refractory indolent non-Hodgkin lymphoma (ZUMA-5)

Clinical Trials & Observations
Sattva S. Neelapu, Julio C. Chavez, Alison R. Sehgal, Narendranath Epperla, Matthew Ulrickson, Emmanuel Bachy, Pashna N. Munshi, Carla Casulo, David G. Maloney, Sven de Vos, Ran Reshef, Lori A. Leslie, Olalekan O. Oluwole, Ibrahim Yakoub-Agha, Rashmi Khanal, Joseph Rosenblatt, Ronald Korn, Weixin Peng, Christine Lui, Jacob Wulff, Rhine Shen, Soumya Poddar, A. Scott Jung, Harry Miao, Sara Beygi, Caron A. Jacobson
Journal: Blood
Blood (2024) 143 (6): 496–506.
https://doi.org/10.1182/blood.2023021243
Published: 2024
Includes: Supplemental data
Journal Articles

Comparative Effectiveness of Axicabtagene Ciloleucel Vs Historical Standard-of-Care in Patients with Relapsed or Refractory Follicular Lymphoma: An Analysis of CIBMTR and SCHOLAR-5 Data

Swetha Kambhampati, Hai-Lin Wang, Jiali Yan, Alex F. Herrera, Matthew J. Frank, Leslie L. Popplewell, Nausheen Ahmed, Yi Lin, Frederick L. Locke, Paola Ghione, John G. Gribben, Timothy Best, Christine Fu, Sara Beygi, Markqayne D Ray, John Bian, Zhen-Huan Hu, Fang Sun, Marcelo Pasquini, Caron A. Jacobson
Journal: Blood
Blood (2023) 142 (Supplement 1): 2121.
https://doi.org/10.1182/blood-2023-178629
Published: 2023
Journal Articles

Improved Overall Survival with Axicabtagene Ciloleucel Vs Standard of Care in Second-Line Large B-Cell Lymphoma Among the Elderly: A Subgroup Analysis of ZUMA-7

Marie José Kersten, Umar Farooq, Aaron P. Rapoport, Frederick L. Locke, Lori A. Leslie, Armin Ghobadi, David B. Miklos, Caron A. Jacobson, Javier L. Munoz, Patrick B Johnston, Samantha M. Jaglowski, Ian W. Flinn, Tom van Meerten, Miguel-Angel Perales, Peter Vandenberghe, Peter A. Riedell, Kathleen Dorritie, David Szwajcer, Dimitrios Tzachanis, Saran Vardhanabhuti, Linqiu Du, Simone Filosto, Shilpa A. Shahani, Christina To, Jason Westin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1761.
https://doi.org/10.1182/blood-2023-173873
Published: 2023
Journal Articles

Pre- and Post-Treatment Immune Contexture Correlates with Long Term Response in Large B Cell Lymphoma Patients Treated with Axicabtagene Ciloleucel (axi-cel)

Mike Mattie, Melanie Grosso, Aurelie Auguste, Denis Arnaud, Frederick L. Locke, Sattva S. Neelapu, David B. Miklos, Caron A Jacobson, Lazaros J. Lekakis, Yi Lin, Armin Ghobadi, Jenny J. Kim, Jenny Nater, Rhine R. Shen, Jerome Galon
Journal: Blood
Blood (2023) 142 (Supplement 1): 226.
https://doi.org/10.1182/blood-2023-187574
Published: 2023
Journal Articles

Baseline Immune State and T Cell Clonal Kinetics Are Associated with Response to CAR-T Therapy in Large B-Cell Lymphoma

Katie Maurer, Isabella N. Grabski, Roch Houot, Satyen H Gohil, Shogo Miura, Robert A. Redd, Haoxiang Lyu, Wesley S Lu, Brodie Miles, Mike Mattie, Yohei Arihara, Mikaela M. McDonough, Carol Reynolds, Michela Ansuinelli, Shuqiang Li, Kenneth J. Livak, Jerome Ritz, Scott Rodig, Rafael A. Irizarry, Philippe Armand, Catherine J Wu, Caron A. Jacobson
Journal: Blood
Blood (2023) 142 (Supplement 1): 223.
https://doi.org/10.1182/blood-2023-180819
Published: 2023
Journal Articles

A Phase I Study of Copanlisib and Venetoclax in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Jennifer L Crombie, Austin I Kim, Nancy L. Bartlett, Robert A. Redd, Victoria Patterson, Celeste Carey, Sobana Balasubramanian, Oreofe O. Odejide, Reid W. Merryman, Ann LaCasce, Caron A Jacobson, Eric Jacobsen, Erin M Parry, David C Fisher, Alex F. Herrera, Matthew S Davids, Margaret A. Shipp, Philippe Armand, Geoffrey P. Shouse
Journal: Blood
Blood (2023) 142 (Supplement 1): 1735.
https://doi.org/10.1182/blood-2023-181067
Published: 2023
Journal Articles

Outcomes of Patients with Relapsed/Refractory Mantle Cell Lymphoma (R/R MCL) Treated with Brexucabtagene Autoleucel (Brexu-cel) in ZUMA-2 and ZUMA-18, an Expanded Access Study

Andre Goy, Caron A. Jacobson, Ian W. Flinn, Brian T. Hill, Wen-Kai Weng, Luke Mountjoy, Oluwole Olalekan, Dan Zheng, Ana Nunes, Wangshu Zhang, Rhine R. Shen, Ioana Kloos, Michael L. Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 106.
https://doi.org/10.1182/blood-2023-174273
Published: 2023
Journal Articles

Trial-in-Progress: A Phase 1/2 Multi-Center Study of Onct-808, a ROR1-Specific CAR T, in Adult Patients with Relapsed/Refractory Aggressive B Cell Lymphoma

Michael L. Wang, Matthew J. Frigault, Salim Yazji, Yisrael Katz, James Robinson, James B. Breitmeyer, Matthew G. Mei, Caron A Jacobson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4857.
https://doi.org/10.1182/blood-2023-180989
Published: 2023
Journal Articles

An Updated Comparison of Clinical Outcomes from 4-Year Follow-up of Zuma-5 (Axicabtagene Ciloleucel) and the International Scholar-5 External Control Cohort in Relapsed/Refractory Follicular Lymphoma

John G. Gribben, Paola Ghione, Maria Lia Palomba, Markqayne D Ray, Eve H Limbrick-Oldfield, Steve Kanters, Sabela Bobillo, Maria Teresa Ribiero, Caron A Jacobson, Sattva S. Neelapu, Herve Ghesquieres, Olga Nikolajeva, Jiali Yan, Hailin Wang, Anik R Patel
Journal: Blood
Blood (2023) 142 (Supplement 1): 4869.
https://doi.org/10.1182/blood-2023-186842
Published: 2023
Journal Articles

Real-World Evidence in the United States (US) of the Impact of Bridging Therapy Prior to Axicabtagene Ciloleucel (Axi-Cel) for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma (R/R LBCL)

Michael Roderick Cook, Roni Shouval, Miguel-Angel Perales, Evandro Bezerra, Alex Niu, Saurabh Dahiya, Loretta J. Nastoupil, Caron A. Jacobson, L. Elizabeth Budde, Amanda L. Olson, Brent R. Logan, Zhen-Huan Hu, Hai-Lin Wang, Zhong-Cheng Luo, Jenny J. Kim, Harry W. Smith, Andrew Lee, Fang Sun, Marcelo Pasquini, Frederick L. Locke
Journal: Blood
Blood (2023) 142 (Supplement 1): 103.
https://doi.org/10.1182/blood-2023-175034
Published: 2023
Journal Articles

Assessment of Early Intervention Strategies for Management of Cytokine Release Syndrome and Neurologic Events after Brexucabtagene Autoleucel (Brexu-Cel) Treatment in Patients with Relapsed or Refractory Mantle Cell Lymphoma (R/R MCL) in ZUMA-2

Olalekan O. Oluwole, Patrick M. Reagan, David B. Miklos, Frederick L. Locke, Andre Goy, Caron A. Jacobson, Javier L. Munoz, Edouard Forcade, Max S. Topp, Dan Zheng, Ana Nunes, Wangshu Zhang, Rhine R. Shen, Ioana Kloos, Marie José Kersten, Michael L. Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2120.
https://doi.org/10.1182/blood-2023-174681
Published: 2023
Journal Articles

Real-World Outcomes of CD19CAR T Cell Therapy in Adult Patients with Relapsed Refractory Transformed Indolent Lymphoma

Swetha Kambhampati, Reid W. Merryman, Yan Wang, Evandro Bezerra, Timothy Voorhees, Ayo S Falade, Madhav R Seshadri, Megumi Bailey, Neil Bailey, Krish Patel, Charalambos Andreadis, Adam S Kittai, Caron A Jacobson, Joycelynne Michelle Palmer, Annette Brown, Alex F. Herrera, L. Elizabeth Budde
Journal: Blood
Blood (2023) 142 (Supplement 1): 3511.
https://doi.org/10.1182/blood-2023-182467
Published: 2023
Journal Articles

Phase I Safety and Preliminary Efficacy of Acalabrutinib, Venetoclax, and Obinutuzumab (AVO) in Patients with Relapsed/Refractory Mantle Cell Lymphoma

Austin I Kim, Philippe Armand, Robert A. Redd, Megan Forsyth, Paul Branch, Samantha Pazienza, Lisa Brennan, Victoria Patterson, Susan M Waisgerber, Reid W. Merryman, David C Fisher, Christine E. Ryan, Inhye E Ahn, Jennifer L Crombie, Oreofe O. Odejide, Ann LaCasce, Caron A Jacobson, Eric Jacobsen, Erin M Parry, Matthew S Davids, Jennifer R. Brown, Arnold S. Freedman, Peter A. Riedell, Mark Alan Murakami
Journal: Blood
Blood (2023) 142 (Supplement 1): 3031.
https://doi.org/10.1182/blood-2023-173103
Published: 2023
Journal Articles

Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy for Richter's Transformation: An International Multicenter Retrospective Study

Adam S Kittai, David A. Bond, Ying Huang, Seema A Bhat, Emily Blyth, John C. Byrd, Julio C Chavez, Matthew S Davids, Jamie P Dela Cruz, Mark R Dowling, Caitlyn Duffy, Carrie I Ho, Caron A Jacobson, Samantha M. Jaglowski, Nitin Jain, Kevin H Lin, Christine McCarthy, Erin M Parry, Manoj Rai, Kerry A Rogers, Aditi Saha, Levanto Schachter, Hamish Scott, Jayastu Senapati, Mazyar Shadman, Tanya Siddiqi, Deborah M. Stephens, Vinay Vanguru, William G. Wierda, Omer Zulfa, Jennifer A. Woyach, Philip A. Thompson
Journal: Blood
Blood (2023) 142 (Supplement 1): 108.
https://doi.org/10.1182/blood-2023-180858
Published: 2023
Journal Articles

Real-World Outcomes of Brexucabtagene Autoleucel (Brexu-cel) for Relapsed or Refractory (R/R) Mantle Cell Lymphoma (MCL): A CIBMTR Subgroup Analysis of High-Risk Characteristics

Swetha Kambhampati, Nausheen Ahmed, Mehdi Hamadani, Soyoung Kim, Michael T. Hemmer, Natalie S. Grover, Mazyar Shadman, Amer Beitinjaneh, L. Elizabeth Budde, James Gerson, Caron A. Jacobson, Frederick L. Locke, Dwivedy S. Nasta, Michael L. Wang, Wen-Kai Weng, Jiali Yan, Ana Nunes, David Dalton, James J. Wu, Amina Abdeldaim, Zhen-Huan Hu, Marcelo Pasquini, Alex F. Herrera
Journal: Blood
Blood (2023) 142 (Supplement 1): 107.
https://doi.org/10.1182/blood-2023-179269
Published: 2023
Journal Articles

A Retrospective Intra-Patient Analysis from ZUMA-5: Axicabtagene Ciloleucel (Axi-Cel) Compared with Prior Standard-of-Care Therapy in Patients with Relapsed/Refractory Follicular Lymphoma

Emmanuel Bachy, Sattva S. Neelapu, Julio C. Chavez, Ibrahim Yakoub-Agha, Christine Lui, Jacob Wulff, Harry Miao, Olga Nikolajeva, Timothy Best, Camille Linot, Caron A. Jacobson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4865.
https://doi.org/10.1182/blood-2023-175055
Published: 2023
Journal Articles

Axicabtagene Ciloleucel (Axi-Cel) in Patients with Relapsed/Refractory Indolent Non-Hodgkin Lymphoma: 4-Year Follow-up from the Phase 2 ZUMA-5 Trial

Sattva S. Neelapu, Julio C. Chavez, Alison R Sehgal, Narendranath Epperla, Matthew L. Ulrickson, Emmanuel Bachy, Pashna N. Munshi, Carla Casulo, David G Maloney, Sven de Vos, Ran Reshef, Lori A. Leslie, Olalekan O. Oluwole, Ibrahim Yakoub-Agha, Rashmi Khanal, Joseph D. Rosenblatt, Weixin Peng, Christine Lui, Jacob Wulff, Rhine R. Shen, Soumya Poddar, Andrew Lee, Harry Miao, Olga Nikolajeva, Caron A. Jacobson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4868.
https://doi.org/10.1182/blood-2023-174914
Published: 2023
Journal Articles

A Phase 2 Study of Acalabrutinib, Umbralisib, and Ublituximab (AU2) in Treatment-Naïve and Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

Inhye E Ahn, Yinglu Zhou, Svitlana Tyekucheva, Hannah Cormier, Stacey M Fernandes, Josie Montegaard, Marykate Kilcommons, Jennifer L Crombie, Reid W. Merryman, Erin M Parry, Philippe Armand, David C Fisher, Caron A Jacobson, Matthew S Davids, Jennifer R. Brown
Journal: Blood
Blood (2023) 142 (Supplement 1): 1914.
https://doi.org/10.1182/blood-2023-180788
Published: 2023