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Journal Articles

Antigen escape as a shared mechanism of resistance to BCMA-directed therapies in multiple myeloma

Brief Report
Ross S. Firestone, Nicholas D. Socci, Tala Shekarkhand, Menglei Zhu, Wei Ge Qin, Malin Hultcrantz, Sham Mailankody, Carlyn Rose Tan, Neha Korde, Alexander M. Lesokhin, Hani Hassoun, Urvi Shah, Kylee H. Maclachlan, Sridevi Rajeeve, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Oscar B. Lahoud, Sergio Giralt, Kazunori Murata, Saad Z. Usmani, David J. Chung
Journal: Blood
Blood (2024) 144 (4): 402–407.
https://doi.org/10.1182/blood.2023023557
Published: 2024
Includes: Supplemental data
Journal Articles

A Phase II Trial of Prophylactic Anakinra to Prevent Neurotoxicity in Patients Receiving Anti-CD19 CAR T-Cell Therapy for Relapsed or Refractory Lymphoma: Final Results from Cohort 2

Karthik Nath, Sean M. Devlin, Craig S Sauter, Maria Lia Palomba, Gunjan L. Shah, Parastoo Bahrami Dahi, Richard J. Lin, Michael Scordo, Miguel-Angel Perales, Lori A. Leslie, Roni Shouval, Sara Bekele, Elizabeth Cathcart, Elena Mead, Bianca Santomasso, Andrei Holodny, Renier Brentjens, Isabelle Riviere, Michel Sadelain, Jae H. Park
Journal: Blood
Blood (2023) 142 (Supplement 1): 357.
https://doi.org/10.1182/blood-2023-174728
Published: 2023
Journal Articles

Successful Incorporation of Electronic Patient Reported Outcomes Using Promis-29 into Standard of Care after Hematopoietic Stem Cell Transplant and Chimeric Antigen Receptor T Cell Therapy

Gunjan L. Shah, Stephanie Lobaugh, Ranjit Sukhu, Sean M. Devlin, Thomas Atkinson, Elizabeth Kemeny, Peter Stetson, Miguel-Angel Perales, Sergio A. Giralt, Michael Scordo
Journal: Blood
Blood (2023) 142 (Supplement 1): 7382.
https://doi.org/10.1182/blood-2023-179330
Published: 2023
Journal Articles

First Fever between Lymphodepletion and Day 30 after CAR-T Cell Therapy: Patterns, Origins, and Implications in Lymphoma Patients

Giovanna Melica, Alejandro Luna, Teng Fei, Magdalena Corona, Parastoo Bahrami Dahi, Joshua Fein, Sergio A. Giralt, Sandeep Raj, Ivan Landego, Richard J. Lin, Maria Lia Palomba, Allison Parascondola, Jae H. Park, Gilles Salles, Susan K. Seo, Amethyst Saldia, Michael Scordo, Ana Alarcon Tomas, Gunjan L. Shah, Miguel-Angel Perales, Ying Taur, Roni Shouval
Journal: Blood
Blood (2023) 142 (Supplement 1): 6907.
https://doi.org/10.1182/blood-2023-181999
Published: 2023
Journal Articles

Evaluation of the Impact of Tocilizumab Use in Recipients of CAR T Cells for Non-Hodgkin Lymphoma

Giulio Cassanello, Efrat Luttwak, Sean M. Devlin, Alejandro Luna De Abia, Magdalena Corona, Ivan Landego, Allison Parascondola, Amethyst Saldia, Ana Alarcon Tomas, Parastoo B. Dahi, Richard J. Lin, M. Lia Palomba, Jae H. Park, Gilles Salles, Miguel-Angel Perales, Michael Scordo, Roni Shouval, Gunjan L. Shah
Journal: Blood
Blood (2023) 142 (Supplement 1): 6898.
https://doi.org/10.1182/blood-2023-190500
Published: 2023
Journal Articles

Evaluating the Effect of Evolving Changes in Serum Biomarkers on the Risk of Progression in Smoldering Multiple Myeloma

Theresia Akhlaghi, David Nemirovsky, Kylee H Maclachlan, Neha Korde, Sham Mailankody, Alexander Lesokhin, Hani Hassoun, Dhwani Patel, Urvi A Shah, Carlyn Tan, Oscar Boutros Lahoud, Heather Landau, Gunjan L. Shah, Michael Scordo, David Chung, Ola Landgren, Sergio A. Giralt, Saad Z Usmani, Andriy Derkach, Malin Hultcrantz
Journal: Blood
Blood (2023) 142 (Supplement 1): 877.
https://doi.org/10.1182/blood-2023-180315
Published: 2023
Journal Articles

CNS Radiotherapy As Bridging Prior to CAR T-Cell Therapy for Non-Hodgkin B-Cell Lymphoma

Gustav Cederquist, Javin Schefflein, Sean M. Devlin, Harper Hubbeling, Kathryn Tringale, Gunjan L. Shah, Ana Alarcon Tomas, Roni Shouval, Carla Hajj, Beatrice Fregonese, Parastoo B. Dahi, Richard J. Lin, Maria Lia Palomba, Miguel-Angel Perales, Gilles Salles, Lorenzo Falchi, Christian Grommes, Michael Scordo, Joachim Yahalom, Brandon S. Imber
Journal: Blood
Blood (2023) 142 (Supplement 1): 4491.
https://doi.org/10.1182/blood-2023-190326
Published: 2023
Journal Articles

Evaluating Tumor-Intrinsic and Patient-Specific Mechanisms of Resistance to Teclistamab in Anti-BCMA Exposed and Naïve Multiple Myeloma

Ross Firestone, Devin McAvoy, Tala Shekarkhand, Edith Serrano, Issam S. Hamadeh, Alice Wang, Menglei Zhu, Dhwani Patel, Carlyn Tan, Malin Hultcrantz, Sham Mailankody, Hani Hassoun, Urvi A Shah, Neha Korde, Kylee H Maclachlan, Heather Landau, Michael Scordo, Gunjan L. Shah, Oscar Boutros Lahoud, Sergio A. Giralt, Kinga K Hosszu, David Chung, Alexander Lesokhin, Saad Z Usmani
Journal: Blood
Blood (2023) 142 (Supplement 1): 333.
https://doi.org/10.1182/blood-2023-187467
Published: 2023
Journal Articles

Identifying Causes of Unscheduled Healthcare Interactions and Changes to Patient Disposition in Individuals Receiving Outpatient Commercial Bispecific Antibody Therapy in Relapsed/Refractory Multiple Myeloma (RRMM)

Anna J Howard, Tala Shekarkhand, Issam S. Hamadeh, Alice Wang, Dhwani Patel, Carlyn Tan, Malin Hultcrantz, Sham Mailankody, Hani Hassoun, Urvi A Shah, Neha Korde, Kylee H Maclachlan, Heather Landau, Michael Scordo, Gunjan L. Shah, Oscar Boutros Lahoud, Sergio A. Giralt, David Chung, Alexander Lesokhin, Saad Z Usmani, Ross Firestone
Journal: Blood
Blood (2023) 142 (Supplement 1): 3707.
https://doi.org/10.1182/blood-2023-187889
Published: 2023
Journal Articles

Detection of CAR-T Cell Persistence with Digital Droplet PCR: Correlation of In Vivo Expansion with Clinical Outcomes in a Cohort of B-Cell Lymphoma Patients

Giulio Cassanello, Laetitia Borsu, Maria E. Arcila, Jinjuan Yao, Amir Momeni Boroujeni, Mark Ewalt, Utsav Patel, Roger Chan, Brandon Gray, Alejandro Luna De Abia, Magdalena Corona, Efrat Luttwak, Ivan Landego, Allison Parascondola, Amethyst Saldia, Maria Lia Palomba, Ana Alarcon Tomas, Jessica R Flynn, Sean M. Devlin, Parastoo B. Dahi, Richard J. Lin, Michael Scordo, Roni Shouval, Gilles Salles, Miguel-Angel Perales, Gunjan L. Shah
Journal: Blood
Blood (2023) 142 (Supplement 1): 7156.
https://doi.org/10.1182/blood-2023-190332
Published: 2023
Journal Articles

Carfilzomib, Lenalidomide and Dexamethasone (KRd) As Induction Therapy in High-Risk Newly Diagnosed Multiple Myeloma

Carlyn Tan, Neha Korde, Andriy Derkach, Malin Hultcrantz, Kylee H Maclachlan, Hani Hassoun, Sham Mailankody, Urvi A Shah, Sridevi Rajeeve, Dhwani Patel, Alexander Lesokhin, Oscar Boutros Lahoud, Gunjan L. Shah, Michael Scordo, David Chung, Heather Landau, Sergio A. Giralt, Craig C. Hofmeister, Jonathan L. Kaufman, Ajay K. Nooka, Saad Z Usmani, Sagar Lonial, Nisha S. Joseph
Journal: Blood
Blood (2023) 142 (Supplement 1): 1996.
https://doi.org/10.1182/blood-2023-190279
Published: 2023
Journal Articles

From Widespread to Tailored Antifungal Prophylaxis in Lymphoma Patients Treated with CD19 CAR T- Cell Therapy: Less Is Better

Giovanna Melica, Alejandro Luna De Abia, Magdalena Corona, Joshua Fein, Parastoo B Dahi, Sergio A. Giralt, Ivan Landego, Richard J. Lin, Maria Lia Palomba, Allison Parascondola, Jae H. Park, Gilles Salles, Amethyst Saldia, Michael Scordo, Ana Alarcon Tomas, Gunjan L. Shah, Roni Shouval, Ying Taur, Miguel-Angel Perales, Susan K. Seo
Journal: Blood
Blood (2023) 142 (Supplement 1): 3514.
https://doi.org/10.1182/blood-2023-181997
Published: 2023
Journal Articles

Impact of Response to Systemic Bridging Therapy on Clinical Outcomes and Cytokine Profiles in Patients Receiving CD19- CAR T-Cell Therapy for B-Cell Lymphoma

Beatriz Wills, Roni Shouval, Jessica R. Flynn, Sean M. Devlin, Allison Parascondola, Amethyst Saldia, Brandon S. Imber, Ana Alarcon Tomas, Ivan Landego, Richard J. Lin, Michael Scordo, Parastoo Bahrami Dahi, Gunjan L. Shah, Andrew Ip, Lori A Leslie, Hyung Chan Suh, Gilles Salles, Miguel-Angel Perales, Maria Lia Palomba
Journal: Blood
Blood (2023) 142 (Supplement 1): 3014.
https://doi.org/10.1182/blood-2023-181116
Published: 2023
Journal Articles

Patterns of Cytokine Release Syndrome with Teclistamab in Relapsed/Refractory Multiple Myeloma with or without Prior T-Cell Redirection Therapy

Issam S. Hamadeh, Tala Shekarkhand, Colin Rueda, Ross Firestone, Alice Wang, Neha Korde, Malin Hultcrantz, Alexander Lesokhin, Sham Mailankody, Hani Hassoun, Urvi A Shah, Kylee H Maclachlan, Dhwani Patel, Gunjan L. Shah, Michael Scordo, Oscar Boutros Lahoud, David Chung, Heather Landau, Sergio A. Giralt, Saad Z Usmani, Carlyn Rose Tan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1961.
https://doi.org/10.1182/blood-2023-180283
Published: 2023
Journal Articles

Responses and Outcomes after Second-Line Therapy in Transplant-Eligible Patients with DLBCL Relapse over 1 Year after First-Line Therapy

David A Qualls, Gunjan L. Shah, Roni Shouval, Philip Caron, Kevin A. David, Lorenzo Falchi, Paola Ghione, Paul A. Hamlin, Steven M. Horwitz, Andrew M. Intlekofer, William Johnson, Anita Kumar, Oscar Boutros Lahoud, Jennifer Kimberly Lue, Alison Moskowitz, Ariela Noy, Maria Lia Palomba, Pallawi Torka, Santosha A Vardhana, Andrew D. Zelenetz, Michelle Okwali, Parastoo Bahrami Dahi, Michael Scordo, Richard J. Lin, Miguel-Angel Perales, Gilles Salles
Journal: Blood
Blood (2023) 142 (Supplement 1): 4970.
https://doi.org/10.1182/blood-2023-182733
Published: 2023
Journal Articles

Comparison of Bendamustine Versus Fludarabine/ Cyclophosphamide Lymphodepletion in Adult Patients Receiving CD19 CAR-T Cell Therapy

Ivan Landego, David Nemirovsky, Sean M. Devlin, Beatriz Wills, Allison Parascondola, Amethyst Saldia, Parastoo B. Dahi, Ana Alarcon Tomas, Andrew Ip, Hyung C Suh, Lori A. Leslie, Karthik Nath, Sergio A. Giralt, Richard J. Lin, Maria Lia Palomba, Gilles Salles, Gunjan L. Shah, Roni Shouval, Miguel-Angel Perales, Michael Scordo
Journal: Blood
Blood (2023) 142 (Supplement 1): 3510.
https://doi.org/10.1182/blood-2023-189349
Published: 2023
Journal Articles

Dynamics of Radiomic Features Following Bridging Therapy Determine CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy Outcome

Harper Hubbeling, Doris Leithner, Emily A. Silverman, Jessica R. Flynn, Sean M. Devlin, Gunjan L. Shah, Beatrice Fregonese, Akshay Bedmutha, Beatriz Wills, Ana Alarcon Tomas, Allison Parascondola, Amethyst Saldia, Ivan Landego, Parastoo B. Dahi, Sergio A. Giralt, Richard J. Lin, Michael Scordo, Gilles Salles, Joachim Yahalom, Maria Lia Palomba, Heiko Schoder, Miguel-Angel Perales, Roni Shouval, Brandon S. Imber
Journal: Blood
Blood (2023) 142 (Supplement 1): 2123.
https://doi.org/10.1182/blood-2023-187763
Published: 2023
Journal Articles

Pilot Study of Longitudinal Geriatric Assessment and Neurocognitive Evaluation in CAR T-Cell Therapy for Older Patients with Relapsed Refractory, Large B-Cell Lymphoma

Richard J. Lin, Soo Jung Kim, Denise Correa, Theresa A Elko, Stephanie Lobaugh, Raymond Baser, Adrian Koch, Danielle M Hanley, M. Lia Palomba, Parastoo B. Dahi, Michael Scordo, Gunjan L. Shah, Craig S Sauter, Katherine Nagel, Danielle Engstler, Nicole Lee, Emma Pavkovic, Jae H. Park, Miguel-Angel Perales, Sean M. Devlin, Beatriz Korc-Grodzicki, Paul A. Hamlin, Sergio A. Giralt
Journal: Blood
Blood (2023) 142 (Supplement 1): 7406.
https://doi.org/10.1182/blood-2023-190497
Published: 2023
Journal Articles

Higher CD4+ T Cell Counts after CAR-T in Large B-Cell Lymphomas Are Significantly Associated with Better Overall Survival

Danny Luan, Roni Shouval, Teng Fei, Efrat Luttwak, Alejandro Luna, Magdalena Corona, Maria Lia Palomba, Allison Parascondola, Michael Scordo, Gunjan L. Shah, Susan DeWolf, Miguel-Angel Perales
Journal: Blood
Blood (2023) 142 (Supplement 1): 4812.
https://doi.org/10.1182/blood-2023-184909
Published: 2023
Journal Articles

Chimeric Antigen Receptor T-Cell (CAR-T) Therapy in Secondary Central Nervous System Large B-Cell Lymphoma (SCNSL): A Multicenter Retrospective Analysis

Gulrayz Ahmed, Aseel Alsouqi, Aniko Szabo, Alexandra E. Rojek, Peter A. Riedell, Farrukh T. Awan, Laura Samples, Mazyar Shadman, Marie Hu, Veronika Bachanova, William Wesson, Nausheen Ahmed, Madiha Iqbal, Mohamed A. Kharfan-Dabaja, Michael Scordo, Patrick Connor Johnson, Yi-Bin Chen, Sawa Ito, Mehdi Hamadani, Matthew J. Frigault
Journal: Blood
Blood (2023) 142 (Supplement 1): 3088.
https://doi.org/10.1182/blood-2023-184345
Published: 2023