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Journal Articles

Second primary malignancies in multiple myeloma: Incidence, survival and prognostic factors from a large single-center observational study

Free
Noriko Nishimura, Andriy Derkach, Kelly Barnett, Tala Shekarkhand, Issam Hamadeh, Heather Landau, Michael Scordo, Gunjan Shah, Roni Shouval, Ross Firestone, Sridevi Rajeeve, Francesco Maura, Hamza Hashmi, Maximillian Merz, Malin Hultcrantz, Neha Korde, Alexander Lesokhin, Sham Mailankody, Urvi Shah, Kylee Maclachlan, Carlyn Tan, Sergio Giralt, Saad Usmani, Hani Hassoun
Journal: Blood
Blood (2025) 146 (Supplement 1): 2213.
https://doi.org/10.1182/blood-2025-2213
Published: 2025
Journal Articles

Low dose tocilizumab for mitigation of cytokine release syndrome with bispecific antibodies in relapsed/refractory multiple myeloma

Free
Issam Hamadeh, Maximillian Merz, Andriy Derkach, Tala Shekarkhand, Alexander Lesokhin, Sham Mailankody, Malin Hultcrantz, Carlyn Tan, Hani Hassoun, Urvi Shah, Kylee Maclachlan, Sridevi Rajeeve, Hamza Hashmi, Francesco Maura, Ross Firestone, Alice Wang, Dhwani Patel, Michael Scordo, Gunjan Shah, Heather Landau, Sergio Giralt, Saad Usmani, Neha Korde
Journal: Blood
Blood (2025) 146 (Supplement 1): 2210.
https://doi.org/10.1182/blood-2025-2210
Published: 2025
Journal Articles

Correlative biomarker analyses of etentamig in patients with Relapsed/Refractory multiple myeloma (RRMM) at optimal dose support its potential to maximize T-cell activity with rapid and transient proinflammatory cytokine responses

Free
Aarif Ahsan, Christine Mantis, Adam Luo, Pingping Zheng, Wei Liu, Catherine Zhang, Cesar Rodriguez, Peter Voorhees, Anita D'Souza, Alfred Chung, Sascha Tuchman, Hana Safah, John Mckay, Katja Weisel, Raphael Teipel, Neha Korde, Ravi Vij, Shaji Kumar, Muhamed Baljevic, Hira Mian, Rajvineeth Kumar Pothacamury, Anders Svensson, Chetasi Talati, Jeremy Ross
Journal: Blood
Blood (2025) 146 (Supplement 1): 2204.
https://doi.org/10.1182/blood-2025-2204
Published: 2025
Journal Articles

Ultra-sensitive detection of clonal m-protein by mass spectrometry enhances detection of residual disease: Results from A phase 1 study of etentamig monotherapy in patients with relapsed or refractory multiple myeloma

Free
Aarif Ahsan, Adam Luo, Cesar Rodriguez Valdes, Peter Voorhees, Anita D'Souza, Alfred Chung, Sascha Tuchman, Hana Safah, John Mckay, Katja Weisel, Raphael Teipel, Neha Korde, Ravi Vij, Shaji Kumar, Thomas Doerr, Rajvineeth Kumar Pothacamury, Chetasi Talati, Brenda Chyla, Jeremy Ross
Journal: Blood
Blood (2025) 146 (Supplement 1): 5813.
https://doi.org/10.1182/blood-2025-5813
Published: 2025
Journal Articles

Functionally high-risk disease is associated with inferior outcomes after chimeric antigen receptor T-cell therapy for relapsed refractory multiple myeloma

Free
Tara Sebastian, Hamza Hashmi, Ross Firestone, Eric Jurgens, Sridevi Rajeeve, Tasmin Farzana, Maximilian Merz, Carlyn Tan, Kylee Maclachlan, Francesco Maura, Neha Korde, Hani Hassoun, Urvi Shah, Malin Hultcrantz, Heather Landau, Michael Scordo, Alexander Lesokhin, Andriy Derkach, David Nemirovsky, Sergio Giralt, Sham Mailankody, Saad Usmani
Journal: Blood
Blood (2025) 146 (Supplement 1): 2291.
https://doi.org/10.1182/blood-2025-2291
Published: 2025
Journal Articles

Final results of a multi-center phase 2 trial of isatuximab-lenalidomide in patients with high risk smoldering multiple myeloma (HRSMM)

Free
Sheeba Thomas, Elisabet Manasanch, Sundar Jagannath, Neha Korde, Hans Lee, David Berrios, Krina Patel, Swami Iyer, Sham Mailankody, Behrang Amini, Pei Lin, Zuzana Berkova, Donna Weber, Gregory Kaufman, Lei Feng, Michelle Hildebrandt, Linghua Wang, Sattva Neelapu, Robert Orlowski, Ola Landgren
Journal: Blood
Blood (2025) 146 (Supplement 1): 5834.
https://doi.org/10.1182/blood-2025-5834
Published: 2025
Journal Articles

Lenalidomide-related diarrhea is associated with gut microbiota dysbiosis and disruption of the bile acid pool

Free
Kevin Miller, Teng Fei, Ruben Ramos, Ana Catarina Gradissimo De Oliveira, Jennifer Haber, Minsu Jaun, Francesca Castro, Andriy Derkach, Issam Hamadeh, Kylee Maclachlan, Malin Hultcrantz, Hani Hassoun, Sham Mailankody, Sridevi Rajeeve, Francesco Maura, Maximillian Merz, Hamza Hashmi, Ross Firestone, Eric Jurgens, Gunjan Shah, Michael Scordo, Heather Landau, Jonathan Peled, Sergio Giralt, Neha Korde, Saad Usmani, Urvi Shah, Alexander Lesokhin
Journal: Blood
Blood (2025) 146 (Supplement 1): 2233.
https://doi.org/10.1182/blood-2025-2233
Published: 2025
Journal Articles

On the cellular origins of multiple myeloma

Free
Dennis Lee, Patrick Blaney, Reva Shenwai, Sanghoon Lee, Di Zhang, Marc Braunstein, David Kaminetzky, Lisa Cervia, Kern Hast, Timothy Chu, Lara Winterkorn, Benjamin Diamond, Neha Korde, Alexander Lesokhin, Elizabeth Brown, Nicolas Robine, Kylee Maclachlan, Francesco Maura, Saad Usmani, Ola Landgren, Brian Walker, Faith Davies, Iryna Berezniuk, Oscar Lahoud, Christopher Park, Gareth Morgan
Journal: Blood
Blood (2025) 146 (Supplement 1): 5694.
https://doi.org/10.1182/blood-2025-5694
Published: 2025
Journal Articles

Cytogenetic subgroup analysis of the advance trial: A randomized multi-center study of carfilzomib, lenalidomide and dexamethasone (KRd) with or without daratumumab (D) in patients with newly diagnosed multiple myeloma (NDMM)

Free
Michael Durante, J Christine Ye, Jens Hillengass, Douglas Sborov, James Hoffman, Benjamin Diamond, David Coffey, Marcella Kaddoura, Abhishek Pandey, Kellye Koubek, Stephanie Mompoint, Sindy Gutierrez, Caterine Diaz, Michelle Armogan, Rachid Baz, Robert Orlowski, Thomas Jandl, Neha Korde, Kenneth Shain, Dickran Kazandjian, Ola Landgren
Journal: Blood
Blood (2025) 146 (Supplement 1): 5763.
https://doi.org/10.1182/blood-2025-5763
Published: 2025
Journal Articles

Whole genome sequencing of cell-free DNA for assessment of minimal residual disease in high-risk smoldering multiple myeloma

Free
Chrissy Baker, Elizabeth Hill, Dickran Kazandjian, Marios Papadimitriou, Michael Durante, Abhishek Pandey, Bachisio Ziccheddu, Tomas Jelinek, David Coffey, Brian Walker, Ryan Young, Kylee Maclachlan, Neha Korde, Nickoli Parkinson, Zoe Goldstein, Alexi Runnels, William Hooper, Nicolas Robine, Dan Avi Landau, Francesco Maura, Ola Landgren, Benjamin Diamond
Journal: Blood
Blood (2025) 146 (Supplement 1): 3920.
https://doi.org/10.1182/blood-2025-3920
Published: 2025
Journal Articles

Daratumumab versus lenalidomide as maintenance therapy in newly diagnosed multiple myeloma – final results from a randomized investigator-initiated trial

Free
Sridevi Rajeeve, Andriy Derkach, Sean Devlin, Jeannen Santos, Anna Przemielewska, Tara Sood, Francesca Castro, Thomas Atkinson, Kylee Maclachlan, Hamza Hashmi, Carlyn Tan, Neha Korde, Malin Hultcrantz, Alexander Lesokhin, Hani Hassoun, Parastoo Dahi, Michael Scordo, David Chung, Heather Landau, Gunjan Shah, Ola Landgren, Sergio Giralt, Sham Mailankody, Saad Usmani, Urvi Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 2273.
https://doi.org/10.1182/blood-2025-2273
Published: 2025
Journal Articles

Belantamab mafodotin, nirogacestat, and pomalidomide in patients with relapsed/refractory multiple myeloma

Free
Malin Hultcrantz, Hani Hassoun, Neha Korde, Carlyn Tan, Sergio Giralt, Alexander Lesokhin, Kylee Maclachlan, Dhwani Patel, Urvi Shah, Sridevi Rajeeve, Hamza Hashmi, Andriy Derkach, Ross Firestone, Linh Tran, Meredith Hyland, Kazunori Murata, Kevin Herrera, Karlo Perica, Saad Usmani, Sham Mailankody
Journal: Blood
Blood (2025) 146 (Supplement 1): 4060.
https://doi.org/10.1182/blood-2025-4060
Published: 2025
Journal Articles

Phase II trial of maintenance therapy with iberdomide after autologous hematopoietic cell transplant for patients with multiple myeloma previously treated with lenalidomide

Free
Natalia Tijaro Ovalle, Malin Hultcrantz, Khayla Leiva, Molly Hogan, Ambika Datta, Anjali Patel, Hamza Hashmi, Hani Hassoun, Neha Korde, Alexander Lesokhin, Kylee Maclachlan, Sham Mailankody, Sridevi Rajeeve, Urvi Shah, Carlyn Tan, Saad Usmani, David Chung, Heather Landau, Michael Scordo, Sergio Giralt, Gunjan Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 4048.
https://doi.org/10.1182/blood-2025-4048
Published: 2025
Journal Articles

Effectiveness of remote patient monitoring in enabling outpatient step-up dosing for bispecifics at a large academic cancer center in the USA

Free
Sridevi Rajeeve, Matt Wilkes, Nicole Zahradka, Maithili Deshpande, Alice Wang, Issam Hamadeh, Kelly Aliaga, Katie Jones, Kylee Maclachlan, Hamza Hashmi, Carlyn Tan, Malin Hultcrantz, Alexander Lesokhin, Hani Hassoun, Maximillian Merz, Francesco Maura, Parastoo Dahi, Michael Scordo, Heather Landau, Gunjan Shah, Sergio Giralt, Sham Mailankody, Felice Yang, Niodita Gupta-Werner, Tonya Le Blanc, Jessica Fowler, Shuchita Kaila, Saad Usmani, Neha Korde
Journal: Blood
Blood (2025) 146 (Supplement 1): 2751.
https://doi.org/10.1182/blood-2025-2751
Published: 2025
Journal Articles

Disease burden by NGS in bone marrow and peripheral blood samples at baseline and after frontline therapy: Subgroup analysis of the advance randomized multi-center study of carfilzomib, lenalidomide and dexamethasone (KRd) with or without daratumumab (D) in patients with newly diagnosed multiple myeloma (NDMM)

Free
Michael Durante, J Christine Ye, Jens Hillengass, Douglas Sborov, James Hoffman, Benjamin Diamond, David Coffey, Marcella Kaddoura, Abhishek Pandey, Kellye Koubek, Stephanie Mompoint, Sindy Gutierrez, Caterine Diaz, Michelle Armogan, Rachid Baz, Robert Orlowski, Thomas Jandl, Neha Korde, Heidi Simmons, Allison Jacob, Kenneth Shain, Dickran Kazandjian, Ola Landgren
Journal: Blood
Blood (2025) 146 (Supplement 1): 7454.
https://doi.org/10.1182/blood-2025-7454
Published: 2025
Journal Articles

Factors associated with remote healthcare utilization in MM patients undergoing autologous stem cell transplantation

Free
Molly Benson, Anna Howard, Isabel Concepcion, Andriy Derkach, Gunjan Shah, Michael Scordo, Heather Landau, Sergio Giralt, Malin Hultcrantz, Carlyn Tan, Sham Mailankody, Hani Hassoun, Hamza Hashmi, Sridevi Rajeeve, Urvi Shah, Neha Korde, Kylee Maclachlan, Francesco Maura, Alexander Lesokhin, Miguel-Angel Perales, David Chung, Saad Usmani, Ross Firestone
Journal: Blood
Blood (2025) 146 (Supplement 1): 2632.
https://doi.org/10.1182/blood-2025-2632
Published: 2025
Journal Articles

Mutationally Enriched Regions of the Non-Coding Genome Harbor Functionally Impactful Mutations That Dysregulate Key Genes Involved in Multiple Myeloma Pathogenesis

Free
Patrick Blaney, Kylee H Maclachlan, Marios Papadimitriou, Aneta Mikulasova, Dylan C Gagler, Marc J Braunstein, Oscar B Lahoud, David Kaminetzky, Yubao Wang, Sanxiong Liu, Di Zhang, Anthony Cirrincione, Alexandra Maria Poos, Bachisio Ziccheddu, Marcella Kaddoura, Monika Chojnacka, Benjamin Diamond, Neha Korde, Alexander M. Lesokhin, Saad Z. Usmani, Leo Rasche, Elias K. Mai, Marc S. Raab, Niels Weinhold, Elizabeth E. Brown, Nicolas Robine, Leif Bergsagel, Brian A. Walker, Ola Landgren, Francesco Maura, Faith E Davies, Gareth Morgan
Journal: Blood
Blood (2024) 144 (Supplement 1): 4655.
https://doi.org/10.1182/blood-2024-211012
Published: 2024
Journal Articles

Impact of Absolute Lymphocyte Count at Pre-Apheresis and Pre-Lymphodepletion on Chimeric Antigen Receptor (CAR)-T Therapy Outcomes in Relapsed Refractory Multiple Myeloma (RRMM)

Free
Noriko Nishimura, Sham Mailankody, Samantha Brown, Sean M. Devlin, Bruno Almeida Costa, Tasmin Farzana, Eric M Jurgens, Ross S Firestone, Karthik Nath, David J. Chung, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Roni Shouval, Hamza Hashmi, Hani Hassoun, Kylee H Maclachlan, Malin Hultcrantz, Neha Korde, Alexander M. Lesokhin, Urvi A. Shah, Carlyn Rose Tan, Sergio A. Giralt, Saad Z. Usmani, Sridevi Rajeeve
Journal: Blood
Blood (2024) 144 (Supplement 1): 1944.
https://doi.org/10.1182/blood-2024-208490
Published: 2024
Journal Articles

Real-World Safety and Early Efficacy of Talquetamab in Patients with Heavily-Pretreated Relapsed/Refractory Multiple Myeloma

Free
Bruno Almeida Costa, Carlyn Rose Tan, Tala Shekarkhand, Ross S Firestone, Eric M Jurgens, Kevin Miller, Alexander M. Lesokhin, Gunjan L. Shah, Neha Korde, Sridevi Rajeeve, David J. Chung, Heather J. Landau, Michael Scordo, Hani Hassoun, Kylee H Maclachlan, Urvi A. Shah, Malin Hultcrantz, Issam S. Hamadeh, Sergio Giralt, Sham Mailankody, Saad Z. Usmani, Hamza Hashmi
Journal: Blood
Blood (2024) 144 (Supplement 1): 7026.
https://doi.org/10.1182/blood-2024-206413
Published: 2024
Journal Articles

Defining the Rates of Cytokine Release Syndrome Associated with Talquetamab Step-up Doses

Free
Issam S. Hamadeh, Tala Shekarkhand, Colin Rueda, Ross S Firestone, Alice X Wang, Neha Korde, Malin Hultcrantz, Alexander M. Lesokhin, Sham Mailankody, Hani Hassoun, Urvi A. Shah, Kylee H Maclachlan, Sridevi Rajeeve, Hamza Hashmi, Gunjan L. Shah, Michael Scordo, David J. Chung, Heather J. Landau, Sergio A. Giralt, Saad Z. Usmani, Carlyn Rose Tan
Journal: Blood
Blood (2024) 144 (Supplement 1): 6990.
https://doi.org/10.1182/blood-2024-209891
Published: 2024