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Journal Articles

Talquetamab plus daratumumab for the treatment of relapsed or refractory multiple myeloma in the TRIMM-2 study

Available to Purchase
Clinical Trials & Observations
Ajai Chari, Niels W. C. J. van de Donk, Bhagirathbhai Dholaria, Katja Weisel, María-Victoria Mateos, Hartmut Goldschmidt, Thomas G. Martin, Daniel Morillo, Donna Reece, Paula Rodríguez-Otero, Manisha Bhutani, Anita D’Souza, Albert Oriol, Laura Rosiñol, Nizar J. Bahlis, Deeksha Vishwamitra, Sheri Skerget, Raluca I. Verona, Kalpana Bakshi, Lijuan Kang, Thomas J. Prior, Lien Vandenberk, Jaszianne Tolbert, Sangmin Lee, M. Damiette Smit, Ralph Wäsch
Journal: Blood
Blood (2025) 146 (24): 2902–2913.
https://doi.org/10.1182/blood.2025029360
Published: 2025
Includes: Supplemental data
Journal Articles

Belantamab mafodotin (belamaf) in combination with bortezomib, lenalidomide, and dexamethasone (VRd) for patients (pts) with transplant-ineligible (TI) newly diagnosed multiple myeloma (NDMM): A focus on treatment efficacy and management/resolution of ocular events in the Phase 1 dreamm-9 study

Free
Saad Usmani, Michał Mielnik, Aránzazu Alonso Alonso, Al-Ola Abdallah, Mamta Garg, Wojciech Janowski, Youngil Koh, Chang-Ki Min, Enrique Ocio, Hang Quach, Karthik Ramasamy, Albert Oriol, Paula Rodriguez-Otero, Ricarda Garcia Sanchez, Irwindeep Sandhu, Katja Weisel, Chris Brawley, Miguel Murillo, Fernando Carreño, Jacqueline Egger, Morrys Kaisermann, Marek Hus
Journal: Blood
Blood (2025) 146 (Supplement 1): 5840.
https://doi.org/10.1182/blood-2025-5840
Published: 2025
Journal Articles

Etentamig plus pomalidomide-dexamethasone combination therapy in relapsed or refractory multiple myeloma: A phase 1b dose-escalation and safety expansion study

Free
Peter Voorhees, Anita D'Souza, Hang Quach, Sabine Gaerditz, Estrella Carrillo-Cruz, Michał Mielnik, Tomasz Wrobel, Matthew Pianko, Dickran Kazandjian, M Hasib Sidiqi, Valerio De Stefano, Cesar Rodriguez Valdes, Shonali Midha, Ariel Grajales-Cruz, Hideki Goto, Satoshi Ito, Claudio Cerchione, Ziyi Jin, Shane Lee, Akshanth Polepally, Sneha Rathi, Ross La Motte-Mohs, Kristin D'Amico, Thomas Doerr, Chetasi Talati, Leanne Lash Fleming, Linda Ho, Katja Weisel, Marek Hus, Joaquin Martinez-Lopez
Journal: Blood
Blood (2025) 146 (Supplement 1): 247.
https://doi.org/10.1182/blood-2025-247
Published: 2025
Journal Articles

Peripheral residual disease activity assessment by MALDI-TOF mass spectrometry in patients with newly-diagnosed multiple myeloma in the GMMG-HD7 study

Free
Jia xiang Jin, Varun Ginde, Stefanie Huhn, Philipp Reichert, Uta Bertsch, Roland Fenk, Britta Besemer, Amelie Boquoi, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Thorsten Peters-Regehr, Christof Scheid, Igor Wolfgang Blau, Carsten Mueller-Tidow, Steffen Luntz, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Müller, Evgenii Shumilov, Wolfgang Knauf, Christian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc Raab, Niels Weinhold, Martin Hoffmann, Axel Benner, Peter Findeisen, Katja Weisel, Hans Salwender, Elias K. Mai, Hartmut Goldschmidt
Journal: Blood
Blood (2025) 146 (Supplement 1): 920.
https://doi.org/10.1182/blood-2025-920
Published: 2025
Journal Articles

Effectiveness of bridging therapy corresponds to improved outcomes after ciltacabtagene autoleucel: Phase 3 CARTITUDE-4 study of patients with relapsed, lenalidomide-refractory multiple myeloma

Free
Binod Dhakal, Shinsuke Iida, M Hasib Sidiqi, Elena Zamagni, Sung-Soo Yoon, Natalie Callander, Cyrille Touzeau, Quanlin Li, Agnes Balogh, Ana Slaughter, Nina Benachour, Carolina Lonardi, Arnab Ghosh, Martin Vogel, Nikoletta Lendvai, Tamar Lengil, Mythili Koneru, Nitin Patel, Octavio Costa, Vrinda Mahajan, Joaquin Martinez-Lopez, Kwee Yong, Katja Weisel, Xavier Leleu
Journal: Blood
Blood (2025) 146 (Supplement 1): 2215.
https://doi.org/10.1182/blood-2025-2215
Published: 2025
Journal Articles

Correlative biomarker analyses of etentamig in patients with Relapsed/Refractory multiple myeloma (RRMM) at optimal dose support its potential to maximize T-cell activity with rapid and transient proinflammatory cytokine responses

Free
Aarif Ahsan, Christine Mantis, Adam Luo, Pingping Zheng, Wei Liu, Catherine Zhang, Cesar Rodriguez, Peter Voorhees, Anita D'Souza, Alfred Chung, Sascha Tuchman, Hana Safah, John Mckay, Katja Weisel, Raphael Teipel, Neha Korde, Ravi Vij, Shaji Kumar, Muhamed Baljevic, Hira Mian, Rajvineeth Kumar Pothacamury, Anders Svensson, Chetasi Talati, Jeremy Ross
Journal: Blood
Blood (2025) 146 (Supplement 1): 2204.
https://doi.org/10.1182/blood-2025-2204
Published: 2025
Journal Articles

Health-related quality of life (HRQoL) in patients with newly diagnosed multiple myeloma (NDMM) eligible for transplantation and treated with isatuximab, lenalidomide, bortezomib, and dexamethasone (Isa-RVd) versus rvd alone: Results from part 1 of the GMMG-HD7 study

Free
Elias K. Mai, Uta Bertsch, Roland Fenk, Britta Besemer, Amelie Boquoi, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Christian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc Raab, Martin Hoffmann, Erin Comerford, Maeva Kyheng, Feng Lin, Stephanie Rhoten, Tatiana Lavrova, Hans Salwender, Katja Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2025) 146 (Supplement 1): 2263.
https://doi.org/10.1182/blood-2025-2263
Published: 2025
Journal Articles

The evolution to hepta-refractory myeloma involves sequential loss of CD38, BCMA and GPRC5D

Free
Christine Riedhammer, Marietta Truger, Holly Lee, Lisa Leypoldt, Manja Meggendorfer, Stephan Hutter, Heiko Mueller, Julia Mersi, Sofie-Katrin Kadel, Moutaz Helal, Nazia Afrin, Andreas Rosenwald, Elena Gerhard-Hartmann, Jan Krönke, Torsten Haferlach, Claudia Haferlach, Katja Weisel, Hermann Einsele, Paola Neri, K. Martin Kortüm, Johannes Waldschmidt, Nizar Bahlis, Niels Weinhold, Leo Rasche
Journal: Blood
Blood (2025) 146 (Supplement 1): 5785.
https://doi.org/10.1182/blood-2025-5785
Published: 2025
Journal Articles

Trial in progress: QUINTESSENTIAL-2—a phase 3 study of arlocabtagene autoleucel versus standard of care in adult patients with relapsed and refractory multiple myeloma (RRMM) exposed to lenalidomide

Free
Eyal Lebel, Ahmed Abdulgawad, Stefania Bramanti, Gonzalo Garate, Phoebe Joy Ho, Mikko Keränen, Yaël Cohen, Maja Vase, Amit Khot, Ida Bruun Kristensen, Richard LeBlanc, Cindy Lee, Wojciech Legiec, Hila Magen, María-Victoria Mateos, Danielle Oh, Ludek Pour, Natalia Schutz, Alexandros Spyridonidis, Katja Weisel, Jan Zaucha, Sarah Larson, Asya Varshasvsky, Kimberly Grazioli, Debashree Basudhar, Hongxiang Hu, Ya Meng, Lamis Eldjerou, Susan Bal, Simon Harrison, Rakesh Popat, Marc Raab, Paula Rodriguez-Otero
Journal: Blood
Blood (2025) 146 (Supplement 1): 2302.
https://doi.org/10.1182/blood-2025-2302
Published: 2025
Journal Articles

Ultra-sensitive detection of clonal m-protein by mass spectrometry enhances detection of residual disease: Results from A phase 1 study of etentamig monotherapy in patients with relapsed or refractory multiple myeloma

Free
Aarif Ahsan, Adam Luo, Cesar Rodriguez Valdes, Peter Voorhees, Anita D'Souza, Alfred Chung, Sascha Tuchman, Hana Safah, John Mckay, Katja Weisel, Raphael Teipel, Neha Korde, Ravi Vij, Shaji Kumar, Thomas Doerr, Rajvineeth Kumar Pothacamury, Chetasi Talati, Brenda Chyla, Jeremy Ross
Journal: Blood
Blood (2025) 146 (Supplement 1): 5813.
https://doi.org/10.1182/blood-2025-5813
Published: 2025
Journal Articles

Remission conversion drives outcomes after CAR T-cell therapy for multiple myeloma: a registry analysis from the DRST

Available to Purchase
Clinical Trials & Observations
Maximilian Merz, Nico Gagelmann, Samih Smaili, Sarah Flossdorf, Sandra Sauer, Christof Scheid, Bastian von Tresckow, Gerald Wulf, Katja Weisel, Igor Wolfgang Blau, Monika Engelhardt, Ralph Wäsch, Natalie Schub, Raphael Teipel, Judith Hecker, Johannes Waldschmidt, Britta Besemer, Ben-Niklas Baermann, Simon Call, Leo Hansmann, Francis Ayuketang Ayuk, Marc S. Raab, Hermann Einsele, Uwe Platzbecker, Nicolaus Kröger
Journal: Blood
Blood (2025) 146 (14): 1677–1686.
https://doi.org/10.1182/blood.2025028330
Published: 2025
Includes: Supplemental data
Journal Articles

Pharmacokinetics and Immunogenicity of Abbv-383, a B-Cell Maturation Antigen (BCMA) × CD3 Bispecific T-Cell-Redirecting Antibody, in Patients with Relapsed/Refractory Multiple Myeloma (RRMM)

Free
Akshanth R Polepally, Carla Biesdorf, Muhammad Erfan Uddin, Nils Boehm, Jeremy A Ross, Shaji Kunnathu Kumar, Peter M. Voorhees, Anita D'Souza, Katja Weisel, Orlando Bueno, Chetasi Talati, Rajeev M Menon
Journal: Blood
Blood (2023) 142 (Supplement 1): 6722.
https://doi.org/10.1182/blood-2023-180127
Published: 2023
Journal Articles

Immunological Subgroups Predicting Efficacy of Elotuzumab in Multiple Myeloma Patients: Insights from the GMMG-HD6 Clinical Trial

Free
Gigi Nu Hoang Quy Ton, Katharina Kriegsmann, Mohamed H.S. Awwad, Axel Benner, Uta Bertsch, Britta Besemer, Mathias Hänel, Roland Fenk, Jana Schlenzka, Markus Munder, Jan Dürig, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Andreas Neubauer, Niels Weinhold, Christof Scheid, Roland Schroers, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Christian Kunz, Manfred Hensel, Andrea Seidel-Glätzer, Katja Weisel, Hans Salwender, Carsten Müller-Tidow, Marc S. Raab, Hartmut Goldschmidt, Elias K. Mai, Michael Hundemer
Journal: Blood
Blood (2023) 142 (Supplement 1): 1991.
https://doi.org/10.1182/blood-2023-189169
Published: 2023
Journal Articles

The Phase 2 CARTITUDE-2 Trial: Updated Efficacy and Safety of Ciltacabtagene Autoleucel in Patients with Multiple Myeloma and 1-3 Prior Lines of Therapy (Cohort A) and with Early Relapse after First Line Treatment (Cohort B)

Free
Jens Hillengass, Adam D. Cohen, Mounzer E Agha, Michel Delforge, Tessa Kerre, Wilfried Roeloffzen, Hermann Einsele, Hartmut Goldschmidt, Katja Weisel, Marc S. Raab, Christof Scheid, Sebastien Anguille, Pieter Sonneveld, Sonja Zweegman, Jordan M. Schecter, Kevin C De Braganca, Carolyn Chang Jackson, Philip Vlummens, Helen Varsos, Christina Corsale, Deepu Madduri, Tzu-min Yeh, Pankaj Mistry, Tito Roccia, Qingxuan Song, Muhammad Akram, Octavio Costa Filho, Dong Geng, Yael C. Cohen, Niels W.C.J. Van De Donk
Journal: Blood
Blood (2023) 142 (Supplement 1): 1021.
https://doi.org/10.1182/blood-2023-178882
Published: 2023
Journal Articles

Revealing Novel Mechanisms Underlying Inactivation of Tumor Suppressor Genes on Duplicated Chromosomes in Multiple Myeloma

Free
Anthony Cirrincione, Marcella Kaddoura, Alexandra Maria Poos, Bachisio Ziccheddu, Kylee H Maclachlan, Monika Chojnacka, Benjamin Diamond, Patrick Blaney, Dylan Gagler, Yanming Zhang, Ahmet Dogan, Alexander Lesokhin, Faith E. Davies, Hartmut Goldschmidt, Katja Weisel, Roland Fenk, Elias K. Mai, Neha Korde, Gareth J. Morgan, Marc S. Raab, Saad Z Usmani, Ola Landgren, Niels Weinhold, Francesco Maura
Journal: Blood
Blood (2023) 142 (Supplement 1): 874.
https://doi.org/10.1182/blood-2023-186802
Published: 2023
Journal Articles

Results of the Phase III Randomized Iskia Trial: Isatuximab-Carfilzomib-Lenalidomide-Dexamethasone Vs Carfilzomib-Lenalidomide-Dexamethasone As Pre-Transplant Induction and Post-Transplant Consolidation in Newly Diagnosed Multiple Myeloma Patients

Free
Francesca Gay, Wilfried Roeloffzen, Meletios A. Dimopoulos, Laura Rosiñol, Marjolein van der Klift, Roberto Mina, Albert Oriol Rocafiguera, Eirini Katodritou, Ka Lung Wu, Paula Rodriguez Otero, Roman Hajek, Elisabetta Antonioli, Mark van Duin, Mattia D'Agostino, Joaquin Martinez-Lopez, Elena M. van Leeuwen-Segarceanu, Paola Tacchetti, Niels W.C.J. van de Donk, Katja Weisel, Luděk Pour, Jakub Radocha, Angelo Belotti, Fredrik Schjesvold, Joan Bladé, Hermann Einsele, Pieter Sonneveld, Mario Boccadoro, Annemiek Broijl
Journal: Blood
Blood (2023) 142 (Supplement 1): 4.
https://doi.org/10.1182/blood-2023-177546
Published: 2023
Journal Articles

Impact of Long-Term Treatment with Belantamab Mafodotin on Safety and Efficacy Outcomes in Patients with Relapsed/Refractory Multiple Myeloma in DREAMM-3

Free
Vania T.M Hungria, Katja Weisel, Atanas Radinoff, Sosana Delimpasi, Gabor Mikala, Tamas Masszi, Jian Li, Marcelo Capra, Angelo Maiolino, Vasiliki Pappa, Dominik Chraniuk, Iurii Osipov, Xavier Leleu, Michael Low, Morio Matsumoto, Mary Li, Neal Sule, Margaret Polinkovsky, Randy Davis, Shelley Bright, Astrid McKeown, Joanna Opalinska, Meletios Athanasios Dimopoulos
Journal: Blood
Blood (2023) 142 (Supplement 1): 3357.
https://doi.org/10.1182/blood-2023-178009
Published: 2023
Journal Articles

The Temporal Evolution of Chromosome 1q Gain and Hyperdiploidy and Its Impact on Clinical Outcomes in Multiple Myeloma

Free
Francesco Maura, Marcella Kaddoura, Alexandra Maria Poos, Anthony Cirrincione, Benjamin Diamond, Kylee H Maclachlan, Bachisio Ziccheddu, Elias K. Mai, Hartmut Goldschmidt, Katja Weisel, Roland Fenk, Gareth J. Morgan, Saad Z Usmani, Ola Landgren, Marc S. Raab, Niels Weinhold
Journal: Blood
Blood (2023) 142 (Supplement 1): 638.
https://doi.org/10.1182/blood-2023-182267
Published: 2023
Journal Articles

Updated Safety and Efficacy Results of Abbv-383, a BCMA x CD3 Bispecific T-Cell Redirecting Antibody, in a First-in-Human Phase 1 Study in Patients with Relapsed/Refractory Multiple Myeloma

Free
Ravi Vij, Shaji Kunnathu Kumar, Anita D'Souza, John T Mckay, Peter M. Voorhees, Alfred Chung, Sascha Alexander Tuchman, Neha Korde, Katja Weisel, Raphael Teipel, Orlando Bueno, Zhongling Feng, Tanya S Rosenberg, Rajvineeth Kumar Pothacamury, Akshanth R Polepally, Shane Lee, Ziyi Jin, Jeremy A Ross, Aarif Ahsan, Chetasi Talati, Cesar Rodriguez
Journal: Blood
Blood (2023) 142 (Supplement 1): 3378.
https://doi.org/10.1182/blood-2023-182388
Published: 2023
Journal Articles

Salvage Autologous Transplant and Lenalidomide Maintenance Versus Continuous Lenalidomide/Dexamethasone for Relapsed Multiple Myeloma: Long Term Follow up Results of the Randomized GMMG Phase III Multicenter Trial Relapse

Free
Marc-Andrea Baertsch, Jana Schlenzka, Thomas Hielscher, Marc S. Raab, Sandra Sauer, Maximilian Merz, Elias K. Mai, Carsten Müller-Tidow, Steffen Luntz, Anna Jauch, Peter Brossart, Martin Goerner, Stefan Klein, Bertram Glass, Peter Reimer, Ullrich Graeven, Roland Fenk, Mathias Hänel, Ivana von Metzler, Lindemann Hans W., Christof Scheid, Axel Nogai, Hans Salwender, Richard Noppeney, Britta Besemer, Katja Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2023) 142 (Supplement 1): 782.
https://doi.org/10.1182/blood-2023-178835
Published: 2023