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Saad Z Usmani
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Journal Articles

Dexamethasone dose intensity does not impact outcomes in newly diagnosed multiple myeloma: a secondary SWOG analysis

Clinical Trials & Observations
Rahul Banerjee, Rachael Sexton, Andrew J. Cowan, Aaron S. Rosenberg, Sikander Ailawadhi, S. Vincent Rajkumar, Shaji K Kumar, Angela Dispenzieri, Sagar Lonial, Brian G.M. Durie, Paul G. Richardson, Saad Z Usmani, Antje Hoering, Robert Z Orlowski
Journal: Blood
Blood blood.2024025939.
https://doi.org/10.1182/blood.2024025939
Published: 2024
Includes: Supplemental data
Journal Articles

Efficacy and safety of teclistamab in patients with relapsed/refractory multiple myeloma after BCMA-targeting therapies

Clinical Trials & Observations
Cyrille Touzeau, Amrita Y Krishnan, Philippe Moreau, Aurore Perrot, Saad Z Usmani, Salomon Manier, Michele Cavo, Carmen Martinez Chamorro, Ajay K. Nooka, Thomas G Martin, Lionel Karlin, Xavier Leleu, Nizar J. Bahlis, Britta Besemer, Lixia Pei, Sarah Stein, Shun Xin Wang Lin, Danielle Trancucci, Raluca Verona, Suzette Girgis, Xin Miao, Clarissa Uhlar, Katherine Chastain, Alfred Garfall
Journal: Blood
Blood blood.2023023616.
https://doi.org/10.1182/blood.2023023616
Published: 2024
Includes: Supplemental data
Journal Articles

Correlation of immune fitness with response to teclistamab in relapsed/refractory multiple myeloma in the MajesTEC-1 study

Clinical Trials & Observations
Diana Cortes-Selva, Tatiana Perova, Sheri Skerget, Deeksha Vishwamitra, Sarah Stein, Rengasamy Boominathan, Onsay Lau, Karl Calara-Nielsen, Cuc Davis, Jaymala Patel, Arnob Banerjee, Tara Stephenson, Clarissa Uhlar, Rachel Kobos, Jenna Goldberg, Lixia Pei, Danielle Trancucci, Suzette Girgis, Shun Xin Wang Lin, Liviawati S. Wu, Philippe Moreau, Saad Z. Usmani, Nizar J. Bahlis, Niels W. C. J. van de Donk, Raluca I. Verona
Journal: Blood
Blood (2024) 144 (6): 615–628.
https://doi.org/10.1182/blood.2023022823
Published: 2024
Includes: Supplemental data
Journal Articles

Antigen escape as a shared mechanism of resistance to BCMA-directed therapies in multiple myeloma

Brief Report
Ross S. Firestone, Nicholas D. Socci, Tala Shekarkhand, Menglei Zhu, Wei Ge Qin, Malin Hultcrantz, Sham Mailankody, Carlyn Rose Tan, Neha Korde, Alexander M. Lesokhin, Hani Hassoun, Urvi Shah, Kylee H. Maclachlan, Sridevi Rajeeve, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Oscar B. Lahoud, Sergio Giralt, Kazunori Murata, Saad Z. Usmani, David J. Chung
Journal: Blood
Blood (2024) 144 (4): 402–407.
https://doi.org/10.1182/blood.2023023557
Published: 2024
Includes: Supplemental data
Journal Articles

Clinical Outcomes Associated with Del(17p) in Newly Diagnosed Multiple Myeloma Treated with Triplet and Daratumumab-Based Quadruplet Induction Regimens

Eric Jurgens, Ross Firestone, Kylee H Maclachlan, David Nemirovsky, Andriy Derkach, Malin Hultcrantz, Hani Hassoun, Sham Mailankody, Urvi A Shah, Sridevi Rajeeve, Dhwani Patel, Tala Shekarkhand, Colin Rueda, Yanming Zhang, Oscar Boutros Lahoud, Gunjan L. Shah, Michael Scordo, David Chung, Heather Landau, Sergio A. Giralt, Alexander Lesokhin, Neha Korde, Saad Z Usmani, Carlyn Tan
Journal: Blood
Blood (2023) 142 (Supplement 1): 2024.
https://doi.org/10.1182/blood-2023-190728
Published: 2023
Journal Articles

Single Cell Whole Genome Measurement of Genomic Heterogeneity and Clonal Evolution in Multiple Myeloma

Andrew McPherson, Kylee H Maclachlan, Matthew Myers, Gryte Satas, Ola Landgren, Saad Z Usmani, Sohrab P Shah, Francesco Maura
Journal: Blood
Blood (2023) 142 (Supplement 1): 4722.
https://doi.org/10.1182/blood-2023-191065
Published: 2023
Journal Articles

Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone (DVRd) and Daratumumab, Carfilzomib, Lenalidomide and Dexamethasone (DKRd) As Induction Therapy in Newly Diagnosed Multiple Myeloma

Carlyn Tan, Kylee H Maclachlan, David Nemirovsky, Andriy Derkach, Malin Hultcrantz, Hani Hassoun, Sham Mailankody, Urvi A Shah, Sridevi Rajeeve, Dhwani Patel, Tala Shekarkhand, Colin Rueda, Oscar Boutros Lahoud, Gunjan L. Shah, Michael Scordo, David Chung, Heather Landau, Sergio A. Giralt, Alexander Lesokhin, Saad Z Usmani, Neha Korde
Journal: Blood
Blood (2023) 142 (Supplement 1): 4744.
https://doi.org/10.1182/blood-2023-181868
Published: 2023
Journal Articles

A Whole Foods Plant-Based Weight Loss Intervention Improves Quality of Life, Metabolic, Microbiome and Immune Profile in MGUS/SMM As Well As Progression Trajectory in a Subset - the Nutrivention Trial

Urvi A Shah, Francesca Castro, Andriy Derkach, Teng Fei, Kinga K Hosszu, Devin McAvoy, Susan DeWolf, Justin Cross, Ana Gradissimo, Alexis Nwankwo, Aishwarya Anuraj, Miranda Burge, Blaslov Jenna, Elizabeth Raynor, Jenna Wosleger, Peter Adintori, Michael Pollak, Jenny Paredes Sanchez, Thomas Atkinson, Kylee H Maclachlan, Sham Mailankody, Neha Korde, Carlyn Tan, Malin Hultcrantz, Hani Hassoun, Jonathan U. Peled, Gunjan L. Shah, Michael Scordo, Oscar Boutros Lahoud, David Chung, Heather Landau, Anita D'Souza, Ola Landgren, Sergio A. Giralt, Neil M. Iyengar, Saad Z Usmani, Alexander Lesokhin, Marcel R.M. van den Brink
Journal: Blood
Blood (2023) 142 (Supplement 1): 4771.
https://doi.org/10.1182/blood-2023-182878
Published: 2023
Journal Articles

Trial in Progress: A Phase 1 Study of KTX-1001, an Oral, First-in-Class, Selective MMSET Inhibitor in Patients with Relapsed and Refractory Multiple Myeloma

Jesus G. Berdeja, David Dingli, Sagar Lonial, Andrew J. Yee, Alfred Chung, Cristina Gasparetto, P. Leif Bergsagel, Vivek Roy, Al-Ola Abdallah, Sharmilan Thanendrarajan, Aimaz Afrough, Laura Rosiñol, Suzanne Trudel, Paula Rodriguez Otero, Cyrille Touzeau, Pierre Bories, Soo Bang, Terry Connolly, Michelle Kim, Chad A. Lewis, Bao-Van Tran Linberg, M. Travis Quigley, Ola Landgren, Saad Z Usmani, Maria-Victoria Mateos, David S. Siegel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3391.
https://doi.org/10.1182/blood-2023-174550
Published: 2023
Journal Articles

Contemporary Multiple Myeloma Treatment Patterns Among HCPs and Concordance with Expert Recommendations: Analysis of an Interactive Online Decision Support Tool

Kelly G Brandt, Kristen Rosenthal, Shaji Kunnathu Kumar, Suzanne Lentzsch, Sagar Lonial, Saad Z Usmani, Timothy A. Quill, Joseph R. Mikhael
Journal: Blood
Blood (2023) 142 (Supplement 1): 7284.
https://doi.org/10.1182/blood-2023-180957
Published: 2023
Journal Articles

Safety and Tolerability of Magrolimab Combinations in Patients with Relapsed/Refractory Multiple Myeloma (RRMM): Safety Run-in Results from a Phase 2 Study

Barry Paul, Jirí Minarík, Francesca Cottini, Cristina Gasparetto, Jack Khouri, Mitul Gandhi, Jens Hillengass, Moshe Levy, Michaela Liedtke, Sudhir Manda, Irwindeep Sandhu, Douglas Sborov, Ivan Spicka, Saad Z Usmani, Lin Gu, Michelle Robeson, Michael Murphy, Camille Renard, Christine Chen, Luděk Pour
Journal: Blood
Blood (2023) 142 (Supplement 1): 3383.
https://doi.org/10.1182/blood-2023-186997
Published: 2023
Journal Articles

Ibrutinib in Combination with Revlimid/Dexamethasone (Rd) in Relapsed/Refractory Multiple Myeloma (AFT-15)

Yvonne Efebera, Vera Jean Suman, Shira N. Dinner, Ashley E Rosko, John T Mckay, Peter Barth, Patrick Hagen, Saad Z Usmani, Paul G. Richardson, Jacob P. Laubach
Journal: Blood
Blood (2023) 142 (Supplement 1): 3340.
https://doi.org/10.1182/blood-2023-187296
Published: 2023
Journal Articles

A Comparative Analysis of Infectious Complications in Patients with Multiple Myeloma Treated with BCMA-Targeted Bispecific Antibodies and CAR T-Cell Therapy

Karthik Nath, Tala Shekarkhand, Bruno Almeida Costa, David Nemirovsky, Andriy Derkach, Noriko Nishimura, Tasmin Farzana, Colin Rueda, David Chung, Heather Landau, Oscar Boutros Lahoud, Michael Scordo, Gunjan L. Shah, Hani Hassoun, Kylee H Maclachlan, Neha Korde, Urvi A Shah, Carlyn Rose Tan, Malin Hultcrantz, Sergio A. Giralt, Saad Z Usmani, Zainab Shahid, Sham Mailankody, Alexander Lesokhin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1957.
https://doi.org/10.1182/blood-2023-179413
Published: 2023
Journal Articles

Carfilzomib, Lenalidomide and Dexamethasone (KRd) As Induction Therapy in High-Risk Newly Diagnosed Multiple Myeloma

Carlyn Tan, Neha Korde, Andriy Derkach, Malin Hultcrantz, Kylee H Maclachlan, Hani Hassoun, Sham Mailankody, Urvi A Shah, Sridevi Rajeeve, Dhwani Patel, Alexander Lesokhin, Oscar Boutros Lahoud, Gunjan L. Shah, Michael Scordo, David Chung, Heather Landau, Sergio A. Giralt, Craig C. Hofmeister, Jonathan L. Kaufman, Ajay K. Nooka, Saad Z Usmani, Sagar Lonial, Nisha S. Joseph
Journal: Blood
Blood (2023) 142 (Supplement 1): 1996.
https://doi.org/10.1182/blood-2023-190279
Published: 2023
Journal Articles

Whole-Genome Sequencing Reveals Distinct Mutational Signatures in Multiple Myeloma Patients with African Ancestry Compared with Those of Non-African Ancestry

Kylee H Maclachlan, Patrick Blaney, Anthony Cirrincione, Timothy R. Chu, Alexandra Maria Poos, Elizabeth E. Brown, Elisabet E. Manasanch, Antje Hoering, Liming Hou, Dylan Gagler, Yubao Wang, Sanxiong Liu, Benjamin Diamond, Bachisio Ziccheddu, Marc S. Raab, Niels Weinhold, Ola Landgren, Nicolas Robine, Faith E. Davies, Alexander Lesokhin, Saad Z Usmani, Francesco Maura, Gareth J. Morgan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3764.
https://doi.org/10.1182/blood-2023-190882
Published: 2023
Journal Articles

Patterns of Cytokine Release Syndrome with Teclistamab in Relapsed/Refractory Multiple Myeloma with or without Prior T-Cell Redirection Therapy

Issam S. Hamadeh, Tala Shekarkhand, Colin Rueda, Ross Firestone, Alice Wang, Neha Korde, Malin Hultcrantz, Alexander Lesokhin, Sham Mailankody, Hani Hassoun, Urvi A Shah, Kylee H Maclachlan, Dhwani Patel, Gunjan L. Shah, Michael Scordo, Oscar Boutros Lahoud, David Chung, Heather Landau, Sergio A. Giralt, Saad Z Usmani, Carlyn Rose Tan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1961.
https://doi.org/10.1182/blood-2023-180283
Published: 2023
Journal Articles

Real World Outcomes with Idecabtagene Vicleucel (Ide-Cel) CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma

Surbhi Sidana, Nausheen Ahmed, Othman S Akhtar, Michael Heim, Ruta Brazauskas, Doris K. Hansen, Christopher Ferreri, Ciara Louise L. Freeman, Aimaz Afrough, Larry D. Anderson, Jr., Binod Dhakal, Devender Dhanda, Lohith Gowda, Hamza Hashmi, Melanie Harrison, Amani Kitali, Sayeef Mirza, Jinalben Patel, Pallavi Patwardhan, Saad Z Usmani, Krina K. Patel, Siddhartha Ganguly, Marcelo Pasquini
Journal: Blood
Blood (2023) 142 (Supplement 1): 1027.
https://doi.org/10.1182/blood-2023-181762
Published: 2023
Journal Articles

Evaluating the Effect of Evolving Changes in Serum Biomarkers on the Risk of Progression in Smoldering Multiple Myeloma

Theresia Akhlaghi, David Nemirovsky, Kylee H Maclachlan, Neha Korde, Sham Mailankody, Alexander Lesokhin, Hani Hassoun, Dhwani Patel, Urvi A Shah, Carlyn Tan, Oscar Boutros Lahoud, Heather Landau, Gunjan L. Shah, Michael Scordo, David Chung, Ola Landgren, Sergio A. Giralt, Saad Z Usmani, Andriy Derkach, Malin Hultcrantz
Journal: Blood
Blood (2023) 142 (Supplement 1): 877.
https://doi.org/10.1182/blood-2023-180315
Published: 2023
Journal Articles

The Temporal Evolution of Chromosome 1q Gain and Hyperdiploidy and Its Impact on Clinical Outcomes in Multiple Myeloma

Francesco Maura, Marcella Kaddoura, Alexandra Maria Poos, Anthony Cirrincione, Benjamin Diamond, Kylee H Maclachlan, Bachisio Ziccheddu, Elias K. Mai, Hartmut Goldschmidt, Katja Weisel, Roland Fenk, Gareth J. Morgan, Saad Z Usmani, Ola Landgren, Marc S. Raab, Niels Weinhold
Journal: Blood
Blood (2023) 142 (Supplement 1): 638.
https://doi.org/10.1182/blood-2023-182267
Published: 2023
Journal Articles

Low Target Antigen Expression Mediates Resistance to BCMA CAR T Cell Therapy

Karlo Perica, Sarah Nataraj, Maria Lemdal Sjojstrand, Katherine Nagel, Emma Pavkovic, Erica Payson, Ana Cuenca, Anjali Patel, David Chung, Sham Mailankody, Gunjan L. Shah, Saad Z Usmani, Sergio A. Giralt, Michel Sadelain
Journal: Blood
Blood (2023) 142 (Supplement 1): 2124.
https://doi.org/10.1182/blood-2023-178954
Published: 2023