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Saad Z Usmani
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Journal Articles

T-ICAHT: grading and prognostic impact of thrombocytopenia after CAR T-cell therapy

Open Access
Kai Rejeski, Jaime Sanz, Teng Fei, Monica S. Nair, Hamza Hashmi, Abraham Avigdor, Ofrat Beyar-Katz, Veit L. Bücklein, Kevin J. Curran, Sigrun Einarsdottir, Jonathan H. Esensten, Netta Glaubach, Noa Golan-Accav, Marina Gomez-Llobell, Iris Halamis, Orit Itzhaki, Frederick L. Locke, Sham Mailankody, Ronit Marcus, Marcela V. Maus, M. Lia Palomba, Jae H. Park, Marcelo Pasquini, Sandeep Raj, Sridevi Rajeeve, Gilles Salles, Michael Scordo, Gunjan L. Shah, Avichai Shimoni, Marion Subklewe, Tobias Tix, Saad Z. Usmani, Ori Valid, Yannis K. Valtis, Tsila Zuckerman, Nirali N. Shah, Miguel-Angel Perales, Roni Shouval
Journal: Blood
Blood (2025) 146 (7): 834–846.
https://doi.org/10.1182/blood.2025028833
Published: 2025
Includes: Supplemental data
Journal Articles

Dexamethasone dose intensity does not impact outcomes in newly diagnosed multiple myeloma: a secondary SWOG analysis

Available to Purchase
Clinical Trials & Observations
Rahul Banerjee, Rachael Sexton, Andrew J. Cowan, Aaron S. Rosenberg, Sikander Ailawadhi, S. Vincent Rajkumar, Shaji Kumar, Angela Dispenzieri, Sagar Lonial, Brian G. M. Durie, Paul G. Richardson, Saad Z. Usmani, Antje Hoering, Robert Z. Orlowski
Journal: Blood
Blood (2025) 145 (1): 75–84.
https://doi.org/10.1182/blood.2024025939
Published: 2025
Includes: Supplemental data
Journal Articles

Efficacy and safety of teclistamab in patients with relapsed/refractory multiple myeloma after BCMA-targeting therapies

Available to Purchase
Clinical Trials & Observations
Cyrille Touzeau, Amrita Y. Krishnan, Philippe Moreau, Aurore Perrot, Saad Z. Usmani, Salomon Manier, Michele Cavo, Carmen Martinez Chamorro, Ajay K. Nooka, Thomas G. Martin, Lionel Karlin, Xavier Leleu, Nizar J. Bahlis, Britta Besemer, Lixia Pei, Sarah Stein, Shun Xin Wang Lin, Danielle Trancucci, Raluca I. Verona, Suzette Girgis, Xin Miao, Clarissa M. Uhlar, Katherine Chastain, Alfred L. Garfall
Journal: Blood
Blood (2024) 144 (23): 2375–2388.
https://doi.org/10.1182/blood.2023023616
Published: 2024
Includes: Supplemental data
Journal Articles

Mutationally Enriched Regions of the Non-Coding Genome Harbor Functionally Impactful Mutations That Dysregulate Key Genes Involved in Multiple Myeloma Pathogenesis

Free
Patrick Blaney, Kylee H Maclachlan, Marios Papadimitriou, Aneta Mikulasova, Dylan C Gagler, Marc J Braunstein, Oscar B Lahoud, David Kaminetzky, Yubao Wang, Sanxiong Liu, Di Zhang, Anthony Cirrincione, Alexandra Maria Poos, Bachisio Ziccheddu, Marcella Kaddoura, Monika Chojnacka, Benjamin Diamond, Neha Korde, Alexander M. Lesokhin, Saad Z. Usmani, Leo Rasche, Elias K. Mai, Marc S. Raab, Niels Weinhold, Elizabeth E. Brown, Nicolas Robine, Leif Bergsagel, Brian A. Walker, Ola Landgren, Francesco Maura, Faith E Davies, Gareth Morgan
Journal: Blood
Blood (2024) 144 (Supplement 1): 4655.
https://doi.org/10.1182/blood-2024-211012
Published: 2024
Journal Articles

Feasibility and Implementation of the ASH Research Collaborative's COVID-19 Outcomes in Myeloma and the Impact of Vaccines (COSMIC): A Decentralized, Real-World Evidence Study for Patients with Multiple Myeloma to Monitor Outcomes Related to COVID-19 Vaccines and Infections

Free
William A. Wood, Emily A. Semmel, Shandra James, Donna S. Neuberg, Kathleen Hewitt, Kenneth C. Anderson, Shaji Kumar, Mark A. Schroeder, David J. Chung, Aaron S. Rosenberg, Jeffrey A. Zonder, Samuel M. Rubinstein, Anita D'Souza, Thomas Martin, Ajai Chari, Ravi Vij, Ajay K. Nooka, Brendan M. Weiss, Levi D. Pederson, Andriy Derkach, Susan M. Geyer, Saad Z. Usmani
Journal: Blood
Blood (2024) 144 (Supplement 1): 2393.
https://doi.org/10.1182/blood-2024-203892
Published: 2024
Journal Articles

Real-World Characteristics and Treatment Patterns of Transplant-Eligible Patients with Newly Diagnosed Multiple Myeloma Treated with Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone (DVRd) As Front-Line Treatment: Results from a Multicenter Chart Review Study

Free
Carlyn Rose Tan, Lucio Gordan, Rachel Dileo, Prerna Mewawalla, Sarah M. Larson, Faith E Davies, David Oveisi, Niodita Gupta-Werner, Rohan Medhekar, Annelore Cortoos, Marjohn Armoon, Alvi Rahman, Claire Vanden Eynde, Marie-Hélène Lafeuille, John Reitan, Gary Milkovitch, Joseph Bubalo, Adam Forman, Douglas W Sborov, Shuchita Kaila, Saad Z. Usmani
Journal: Blood
Blood (2024) 144 (Supplement 1): 3760.
https://doi.org/10.1182/blood-2024-201712
Published: 2024
Journal Articles

Impact of Absolute Lymphocyte Count at Pre-Apheresis and Pre-Lymphodepletion on Chimeric Antigen Receptor (CAR)-T Therapy Outcomes in Relapsed Refractory Multiple Myeloma (RRMM)

Free
Noriko Nishimura, Sham Mailankody, Samantha Brown, Sean M. Devlin, Bruno Almeida Costa, Tasmin Farzana, Eric M Jurgens, Ross S Firestone, Karthik Nath, David J. Chung, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Roni Shouval, Hamza Hashmi, Hani Hassoun, Kylee H Maclachlan, Malin Hultcrantz, Neha Korde, Alexander M. Lesokhin, Urvi A. Shah, Carlyn Rose Tan, Sergio A. Giralt, Saad Z. Usmani, Sridevi Rajeeve
Journal: Blood
Blood (2024) 144 (Supplement 1): 1944.
https://doi.org/10.1182/blood-2024-208490
Published: 2024
Journal Articles

First Results from the Dose Escalation Part of the Phase 1 Study of KTX1001, an Oral, First-in-Class, Potent Inhibitor of MMSET/NSD2 for Relapsed/Refractory Multiple Myeloma (RRMM)

Free
Pierre Bories, Cristina Gasparetto, David Dingli, Sagar Lonial, Saad Z. Usmani, Jesus G Berdeja, Alfred Chung, Aimaz Afrough, Laura Rosiñol, Andrew J. Yee, Suzanne Trudel, David S. Siegel, Paula Rodríguez-Otero, Soo Bang, Terry Connolly, Chad A. Lewis, Erin Flynt, Julie Vazquez, Sanjana U. Miskin, Benjamin Winograd, Maria-Victoria Mateos, Cyrille Touzeau, Vivek Roy
Journal: Blood
Blood (2024) 144 (Supplement 1): 3370.
https://doi.org/10.1182/blood-2024-199174
Published: 2024
Journal Articles

Real-World Safety and Early Efficacy of Talquetamab in Patients with Heavily-Pretreated Relapsed/Refractory Multiple Myeloma

Free
Bruno Almeida Costa, Carlyn Rose Tan, Tala Shekarkhand, Ross S Firestone, Eric M Jurgens, Kevin Miller, Alexander M. Lesokhin, Gunjan L. Shah, Neha Korde, Sridevi Rajeeve, David J. Chung, Heather J. Landau, Michael Scordo, Hani Hassoun, Kylee H Maclachlan, Urvi A. Shah, Malin Hultcrantz, Issam S. Hamadeh, Sergio Giralt, Sham Mailankody, Saad Z. Usmani, Hamza Hashmi
Journal: Blood
Blood (2024) 144 (Supplement 1): 7026.
https://doi.org/10.1182/blood-2024-206413
Published: 2024
Journal Articles

Defining the Rates of Cytokine Release Syndrome Associated with Talquetamab Step-up Doses

Free
Issam S. Hamadeh, Tala Shekarkhand, Colin Rueda, Ross S Firestone, Alice X Wang, Neha Korde, Malin Hultcrantz, Alexander M. Lesokhin, Sham Mailankody, Hani Hassoun, Urvi A. Shah, Kylee H Maclachlan, Sridevi Rajeeve, Hamza Hashmi, Gunjan L. Shah, Michael Scordo, David J. Chung, Heather J. Landau, Sergio A. Giralt, Saad Z. Usmani, Carlyn Rose Tan
Journal: Blood
Blood (2024) 144 (Supplement 1): 6990.
https://doi.org/10.1182/blood-2024-209891
Published: 2024
Journal Articles

Whole Genome Sequencing Reveals Lower Apobec-Mutational Activity in Multiple Myeloma Patients with African Ancestry Compared with Those Having European Ancestry

Free
Kylee H Maclachlan, Marios Papadimitriou, Patrick Blaney, Tala Shekarkhand, Timothy R. Chu, Alexandra Maria Poos, Elizabeth Brown, Antje Hoering, Benjamin Diamond, Bachisio Ziccheddu, Marc S. Raab, Niels Weinhold, Ola Landgren, Faith E Davies, Alexander M. Lesokhin, Saad Z. Usmani, Francesco Maura, Gareth Morgan
Journal: Blood
Blood (2024) 144 (Supplement 1): 766.
https://doi.org/10.1182/blood-2024-203675
Published: 2024
Journal Articles

Immune-MRD Status Informs Tumor-MRD Outcome Prognostication in Multiple Myeloma Patients on Lenalidomide Maintenance

Free
Ross S Firestone, Anish Kumar Simhal, Devin McAvoy, Eric M Jurgens, Juan-José Garcés, David Nemirovsky, Andriy Derkach, Kylee H Maclachlan, Malin Hultcrantz, Sham Mailankody, Urvi A. Shah, Carlyn Rose Tan, Neha Korde, Hani Hassoun, Sridevi Rajeeve, Hamza Hashmi, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Sergio Giralt, Benjamin Diamond, Francesco Maura, Kinga K. Hosszu, David J. Chung, Ola Landgren, Saad Z. Usmani, Alexander M. Lesokhin
Journal: Blood
Blood (2024) 144 (Supplement 1): 672.
https://doi.org/10.1182/blood-2024-206646
Published: 2024
Journal Articles

A High-Fiber Dietary Intervention (NUTRIVENTION) in Precursor Plasma Cell Disorders Improves Biomarkers of Disease and May Delay Progression to Myeloma

Free
Urvi A. Shah, Laura Lucia Cogrossi, Andriy Derkach, Francesca Castro, Teng Fei, Susan DeWolf, Juan-Jose Garces, Anna Policastro, Matteo Grioni, Sofia Sisti, Blaslov Jenna, Peter Adintori, Kinga K. Hosszu, Devin McAvoy, Mirae Baichoo, Justin Cross, Aishwarya Anuraj, Charlotte Pohl, Ruben Ramos, Jenny Paredes Sanchez, Brianna Gipson, Kylee H Maclachlan, Ana Gradissimo, Leonardo Boiocchi, Richard Koche, Ronan Chaligne, Torin Block, Neha Korde, Carlyn Rose Tan, Malin Hultcrantz, Hani Hassoun, Gunjan L. Shah, Michael Scordo, Oscar B Lahoud, David J. Chung, Heather J. Landau, Jonathan U. Peled, Nicola Clementi, Marta Chesi, P. Leif Bergsagel, Sham Mailankody, Michael Pollak, Anita D'Souza, Ola Landgren, Susan Chimonas, Sergio Giralt, Saad Z. Usmani, Neil M. Iyengar, Alexander M. Lesokhin, Matteo Bellone, Marcel R.M. van den Brink
Journal: Blood
Blood (2024) 144 (Supplement 1): 671.
https://doi.org/10.1182/blood-2024-202224
Published: 2024
Journal Articles

Phase I Study of Belantamab Mafodotin in Combination with Standard of Care in Transplant-Ineligible Newly Diagnosed Multiple Myeloma: Dreamm-9 Updated Interim Analysis

Free
Saad Z. Usmani, Michal Mielnik, Mamta Garg, Irwindeep Sandhu, Al-Ola Abdallah, Youngil Koh, Albert Oriol, Hang Quach, Katja C. Weisel, Aranzazu Alonso Alonso, Enrique M Ocio, Wojciech Janowski, Chang-Ki Min, Karthik Ramasamy, Ricarda García Sánchez, Paula Rodríguez-Otero, Chris Brawley, Jacqueline L Egger, Morrys C Kaisermann, Marek Hus
Journal: Blood
Blood (2024) 144 (Supplement 1): 497.
https://doi.org/10.1182/blood-2024-198669
Published: 2024
Journal Articles

Development of the ASH Research Collaborative Multiple Myeloma Program: A Multicenter, Real-World Evidence Generation Network

Free
Shaji Kumar, William A. Wood, Kenneth C. Anderson, Emily A. Semmel, Shandra James, Donna S. Neuberg, Kathleen Hewitt, Mark A. Schroeder, David J. Chung, Aaron S. Rosenberg, Jeffrey A. Zonder, Samuel M. Rubinstein, Anita D'Souza, Thomas Martin, Ajai Chari, Ravi Vij, Ajay K. Nooka, Manisha Bhutani, Peter M. Voorhees, Adam S. Sperling, Susan M. Geyer, Michael W. Craige, Sam Walters, Andriy Derkach, Saad Z. Usmani
Journal: Blood
Blood (2024) 144 (Supplement 1): 3792.5.
https://doi.org/10.1182/blood-2024-210957
Published: 2024
Journal Articles

Evaluation of the Safety and Efficacy of Denosumab in Patients with Multiple Myeloma and Severe Renal Impairment; Results from an IMWG Bone Subcommittee Study

Free
Evangelos Terpos, Ioannis Ntanasis-Stathopoulos, Charalampia Kyriakou, Carlyn Rose Tan, Niels Abildgaard, Michel Delforge, Dorotea Beatriz Eugenia Fantl, Cristian M Seehaus, Emilie Carneiro, Cristina João, Saad Z. Usmani
Journal: Blood
Blood (2024) 144 (Supplement 1): 3343.
https://doi.org/10.1182/blood-2024-202539
Published: 2024
Journal Articles

Long-Term Follow-up of Real-World Teclistamab Therapy for Relapsed/Refractory Multiple Myeloma from the IMWG Immunotherapy Working Group Committee

Free
Carlyn Rose Tan, Sireesha Asoori, David Nemirovsky, Andriy Derkach, Larissa Brunaldi, Rakesh Popat, Chris Lau, Efstathios Kastritis, Joaquín Martínez-Lopez, Radhika Bansal, Andre De Menezes Silva Corraes, Saurabh Chhabra, Ricardo D. Parrondo, Sikander Ailawadhi, Despina Fotiou, Meletios Dimopoulos, Kwee Yong, Catriona Mactier, Magdalena Corona, Adolfo Jesús Sáez Marín, Hira Mian, Saad Z. Usmani, Brian G.M. Durie, Thomas G Martin, Yi Lin
Journal: Blood
Blood (2024) 144 (Supplement 1): 5166.
https://doi.org/10.1182/blood-2024-210518
Published: 2024
Journal Articles

Manufacture of Anti-BCMA CAR T Cell Is Feasible after Salvage Autologous or Allogeneic Hematopoietic Stem Cell Transplantation

Free
Gunjan L. Shah, Karlo Perica, Katherine Nagel, Erica Payson, Kinga K. Hosszu, David J. Chung, Heather J. Landau, Michael Scordo, Malin Hultcrantz, Neha Korde, Kylee H Maclachlan, Urvi A. Shah, Carlyn Rose Tan, Hamza Hashmi, Alexander M. Lesokhin, Sridevi Rajeeve, Saad Z. Usmani, Sham Mailankody, Sergio A. Giralt
Journal: Blood
Blood (2024) 144 (Supplement 1): 4850.
https://doi.org/10.1182/blood-2024-212230
Published: 2024
Journal Articles

High WEE1 Expression Correlates with Poor Survival in Multiple Myeloma, Independent of Standard Prognostic Factors

Free
Anish Kumar Simhal, Ross S Firestone, Jung Hun Oh, Larry Norton, Malin Hultcrantz, Saad Z. Usmani, Kylee H Maclachlan, Joseph O. Deasy
Journal: Blood
Blood (2024) 144 (Supplement 1): 6827.
https://doi.org/10.1182/blood-2024-205838
Published: 2024
Journal Articles

Radiation Therapy in a New Era of Multiple Myeloma Management: Trends of Engagement and Radiologic, Biochemical, and Cytogenetic Correlates of Outcomes and Response

Free
Alexandra Dreyfuss, Beatrice Fregonese, Saad Z. Usmani, Sham Mailankody, Brandon S. Imber, Joachim Yahalom
Journal: Blood
Blood (2024) 144 (Supplement 1): 4697.
https://doi.org/10.1182/blood-2024-202628
Published: 2024