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Journal Articles

Tumor mutational burden as a novel biomarker of resistance to CD19 CAR-T cell therapy in large B-cell lymphoma

Free
Sandeep Raj, Aaron Gillmor, Teng Fei, Allison Richards, Magdalena Corona, John Orgera, Anne Marie Noronha, Eugene Brailovski, Gunjan Shah, Zachary Epstein-Peterson, Anthony Daniyan, Alexander Boardman, Jennifer Lue, Lorenzo Falchi, Michael Scordo, Parastoo Dahi, Richard Lin, Yannis Valtis, Efrat Luttwak, Alfredo Rivas-Delgado, Kai Rejeski, Marina Gomez-Llobell, Mohammad Alhomoud, Sigrun Einarsdottir, Silvia Escribano Serrat, Craig Sauter, Lia Palomba, Omar Abdel-Wahab, Marcel van den Brink, Sergio Giralt, Gilles Salles, Jae Park, Mark Donoghue, Benjamin Greenbaum, Miguel-Angel Perales, Roni Shouval
Journal: Blood
Blood (2025) 146 (Supplement 1): 565.
https://doi.org/10.1182/blood-2025-565
Published: 2025
Journal Articles

The simple c-reactive protein (CRP) to albumin ratio (CAR) stratifies treatment response and survival following chimeric antigen receptor T-cell therapy for non-Hodgkin's lymphoma

Free
Richard Lin, Maria Bromberg, Amethyst Saldia, Allison Parascondola, Molly Hogan, Emma Pavkovic, Roni Shouval, Mika Geva, Marina Gomez-Llobell, Silvia Escribano-Serrat, Sigrun Einarsdottir, Sandeep Raj, Lia Palomba, Parastoo Dahi, Michael Scordo, Gunjan Shah, Alexander Boardman, Lorenzo Falchi, Jennifer Lue, Gilles Salles, Craig Sauter, Jae Park, Miguel-Angel Perales, Paul Hamlin, Mithat Gonen, Sergio Giralt
Journal: Blood
Blood (2025) 146 (Supplement 1): 7090.
https://doi.org/10.1182/blood-2025-7090
Published: 2025
Journal Articles

Respiratory viral infections are a significant cause of morbidity during long-term follow-up after CAR T cell therapy: Analysis of 445 episodes

Free
Sigrun Einarsdottir, Maria Isabel Sotelo, Teng Fei, Dedipya Bhamidipati, Magdalena Corona, Silvia Escribano-Serrat, Lorenzo Falchi, Mika Geva, Marina Gomez-Llobell, Jabour Halloun, Malin Hultcrantz, Sapir Israeli, Hazim Khatib, Mini Kamboj, Sham Mailankody, Genovefa Papanicolaou, Lia Palomba, Jae Park, Sandeep Raj, Kai Rejeski, Jaime Sanz, Michael Scordo, Gilles Salles, Susan Seo, Gunjan Shah, Niveen Shibli, Swarn Arya, Yannis Valtis, Saad Usmani, Miguel-Angel Perales, Roni Shouval, Zainab Shahid
Journal: Blood
Blood (2025) 146 (Supplement 1): 4498.
https://doi.org/10.1182/blood-2025-4498
Published: 2025
Journal Articles

Lisocabtagene maraleucel (liso-cel) demonstrates superior efficacy across inflammatory risk subgroups in second-line (2L) large B-cell lymphoma (LBCL): A retrospective analysis of the TRANSFORM study

Free
Pradipta Ray, Abood Okal, Miguel-Angel Perales, Sandeep Raj, Roni Shouval, Eniko Papp, Sahar Ansari, Krishna R. Juluri, Amanda Przespolewski, Debasmita Roy, Ethan Thompson, Julie A. Rytlewski, Eric Bleickardt, Alessandro Crotta, Timothy B. Campbell, Leanne Peiser
Journal: Blood
Blood (2025) 146 (Supplement 1): 3549.
https://doi.org/10.1182/blood-2025-3549
Published: 2025
Journal Articles

Multicenter, randomized Phase II study of epcoritamab for patients with large B-cell lymphomas achieving a partial response after CD19-directed CAR T-cell therapy: Trial in progress

Free
Sandeep Raj, Allison Bock, Sharmila Giri, Dilan Patel, Madiha Iqbal, Natalie Grover, Lori Leslie, Marcus Geer, Olalekan Oluwole, Boyu Hu, Grzegorz Nowakowski, Miguel-Angel Perales
Journal: Blood
Blood (2025) 146 (Supplement 1): 3748.
https://doi.org/10.1182/blood-2025-3748
Published: 2025
Journal Articles

Long-term cardiovascular outcomes in patients with lymphoma who had early post-CAR-T cardiovascular events: A multi-center, international study

Free
Elan Baskir, Tobias Tix, Mohammad Alhomoud, Samantha Brown, Mithat Gonen, Sigrun Einarsdottir, Ali Abed Al Wahad, Alexander Boardman, Veit Buecklein, James Di Palma-Grisi, Zachary Epstein-Peterson, Silvia Escribano Serrat, Lorenzo Falchi, Marina Gomez-Llobell, Andre Goy, Uri Greenbaum, Manhal Habib, Jabour Halloun, Andrew Ip, Sapir Israeli, Richard Lin, Danny Luan, Jennifer Lue, Efrat Luttwak, Lia Palomba, Jae Park, Sandeep Raj, Kai Rejeski, Alfredo Rivas-Delgado, Gilles Salles, Craig Sauter, Michael Scordo, Gunjan Shah, Marion Subklewe, Sergio Giralt, Miguel-Angel Perales, Roni Shouval, Ann Jakubowski, Jennifer Liu, Ofrat Katz, Parastoo Dahi
Journal: Blood
Blood (2025) 146 (Supplement 1): 3723.
https://doi.org/10.1182/blood-2025-3723
Published: 2025
Journal Articles

Impact of holding therapy prior to apheresis on outcomes following CD19 CAR-T cell therapy in large B-cell lymphoma

Free
Marina Gomez-Llobell, Sarah Samorodnitsky, Silvia Escribano Serrat, Jaime Sanz, Sigrun Einarsdottir, Efrat Luttwak, Sandeep Raj, Mohammad Alhomoud, Eugene Brailovski, Kai Rejeski, Maria Isabel Sotelo, Burcin Agridag Ucpinar, Heiko Schoder, Parnian Shobeiri, Alexander Boardman, Jennifer Lue, Parastoo Dahi, Richard Lin, Michael Scordo, Lorenzo Falchi, Craig Sauter, Gunjan Shah, Lia Palomba, Gilles Salles, Jae Park, Mithat Gonen, Roni Shouval, Miguel-Angel Perales
Journal: Blood
Blood (2025) 146 (Supplement 1): 6328.
https://doi.org/10.1182/blood-2025-6328
Published: 2025
Journal Articles

T-ICAHT: grading and prognostic impact of thrombocytopenia after CAR T-cell therapy

Open Access
Kai Rejeski, Jaime Sanz, Teng Fei, Monica S. Nair, Hamza Hashmi, Abraham Avigdor, Ofrat Beyar-Katz, Veit L. Bücklein, Kevin J. Curran, Sigrun Einarsdottir, Jonathan H. Esensten, Netta Glaubach, Noa Golan-Accav, Marina Gomez-Llobell, Iris Halamis, Orit Itzhaki, Frederick L. Locke, Sham Mailankody, Ronit Marcus, Marcela V. Maus, M. Lia Palomba, Jae H. Park, Marcelo Pasquini, Sandeep Raj, Sridevi Rajeeve, Gilles Salles, Michael Scordo, Gunjan L. Shah, Avichai Shimoni, Marion Subklewe, Tobias Tix, Saad Z. Usmani, Ori Valid, Yannis K. Valtis, Tsila Zuckerman, Nirali N. Shah, Miguel-Angel Perales, Roni Shouval
Journal: Blood
Blood (2025) 146 (7): 834–846.
https://doi.org/10.1182/blood.2025028833
Published: 2025
Includes: Supplemental data
Journal Articles

Integrative genomic analysis of DLBCL identifies immune environments associated with bispecific antibody response

Open Access
Sravya Tumuluru, James K. Godfrey, Alan Cooper, Jovian Yu, Xiufen Chen, Brendan W. MacNabb, Girish Venkataraman, Yuanyuan Zha, Benedikt Pelzer, Joo Song, Gerben Duns, Brian J. Sworder, Sandeep Raj, Christopher Bolen, Elicia Penuel, Ekaterina Postovalova, Nikita Kotlov, Aleksander Bagaev, Nathan Fowler, Roni Shouval, Sonali M. Smith, Ash A. Alizadeh, Christian Steidl, Justin Kline
Journal: Blood
Blood (2025) 145 (21): 2460–2472.
https://doi.org/10.1182/blood.2024025355
Published: 2025
Includes: Supplemental data
Journal Articles

An Inflammatory Biomarker Signature Reproducibly Predicts CAR-T Treatment Failure in Patients with Aggressive Lymphoma across the Zuma Trials Cohorts

Free
Sandeep Raj, Jin Xie, Teng Fei, Qinghua Song, Jenny J. Kim, Christina To, Marcel R.M. van den Brink, Miguel-Angel Perales, Mike Mattie, Roni Shouval
Journal: Blood
Blood (2023) 142 (Supplement 1): 224.
https://doi.org/10.1182/blood-2023-173798
Published: 2023
Journal Articles

First Fever between Lymphodepletion and Day 30 after CAR-T Cell Therapy: Patterns, Origins, and Implications in Lymphoma Patients

Free
Giovanna Melica, Alejandro Luna, Teng Fei, Magdalena Corona, Parastoo Bahrami Dahi, Joshua Fein, Sergio A. Giralt, Sandeep Raj, Ivan Landego, Richard J. Lin, Maria Lia Palomba, Allison Parascondola, Jae H. Park, Gilles Salles, Susan K. Seo, Amethyst Saldia, Michael Scordo, Ana Alarcon Tomas, Gunjan L. Shah, Miguel-Angel Perales, Ying Taur, Roni Shouval
Journal: Blood
Blood (2023) 142 (Supplement 1): 6907.
https://doi.org/10.1182/blood-2023-181999
Published: 2023
Journal Articles

Inflammatory Biomarker Clusters Are Predictive of Response and Toxicity in Large B-Cell Lymphoma Treated with CD19 CAR-T Cell Therapy

Free
Sandeep Raj, Miguel-Angel Perales, Joshua A Fein, Ana Alarcon Tomas, Connie Lee Batlevi, Magdalena Corona De Lapuerta, Parastoo B Dahi, Ivetta Danylesko, Shalev Fried, Tyler Funnell, Sergio A. Giralt, Elad Jacoby, Meirav Kedmi, Richard J. Lin, Arnon Nagler, Karthik Nath, Allison Parascondola, M.Lia Palomba, Gilles Salles, Michael Scordo, Gunjan L. Shah, Noga Shem-Tov, Avichai Shimoni, John Slingerland, Moneeza Walji, Ronit Yerushalmi, Abraham Avigdor, Marcel R M van den Brink, Roni Shouval
Journal: Blood
Blood (2022) 140 (Supplement 1): 648–650.
https://doi.org/10.1182/blood-2022-162286
Published: 2022