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Journal Articles

Zanubrutinib, obinutuzumab, and venetoclax for first-line treatment of mantle cell lymphoma with a  TP53 mutation

Clinical Trials & Observations
Anita Kumar, Jacob Soumerai, Jeremy S. Abramson, Jeffrey A. Barnes, Philip Caron, Shalini Chhabra, Maria Chabowska, Ahmet Dogan, Lorenzo Falchi, Clare Grieve, J. Erika Haydu, Patrick Connor Johnson, Ashlee Joseph, Hailey E. Kelly, Alyssa Labarre, Jennifer Kimberly Lue, Rosalba Martignetti, Joanna Mi, Alison Moskowitz, Colette Owens, Sean Plummer, Madeline Puccio, Gilles Salles, Venkatraman Seshan, Elizabeth Simkins, Natalie Slupe, Honglei Zhang, Andrew D. Zelenetz
Journal: Blood
Blood (2025) 145 (5): 497–507.
https://doi.org/10.1182/blood.2024025563
Published: 2025
Includes: Supplemental data
Journal Articles

The current landscape of frontline large B-cell lymphoma trials

Clinical Trials & Observations
David Qualls, Philippe Armand, Gilles Salles
Journal: Blood
Blood (2025) 145 (2): 176–189.
https://doi.org/10.1182/blood.2023023789
Published: 2025
Journal Articles

Treatment Patterns and Outcomes Following Progression of Disease Post-CAR-T Therapy in Relapsed or Refractory Mantle Cell Lymphoma: A Multicenter Analysis

Zachary D. Epstein-Peterson, Anath C. Lionel, Ashlee Joseph, Esther Drill, Suheil Albert Atallah-Yunes, Taylor R. Brooks, Elise A. Chong, Emeline R. Chong, Jamie Dela Cruz, Matthew J. Frank, Andrew Ip, Madiha Iqbal, Caron A. Jacobson, Manali K. Kamdar, Reem Karmali, Kami J. Maddocks, Matthew Matasar, Reid W. Merryman, Javier Munoz, Peter A. Riedell, Christine E. Ryan, Gilles Salles, Craig S. Sauter, Yazeed Sawalha, Roni Shouval, Navika Shukla, Alexander V. Stanisic, Dylan Therwhanger, Herman Van Besien, Yucai Wang, Samuel Yamshon, Andrew D. Zelenetz, Maria Lia Palomba, Preetesh Jain, Anita Kumar
Journal: Blood
Blood (2024) 144 (Supplement 1): 238.
https://doi.org/10.1182/blood-2024-192995
Published: 2024
Journal Articles

Barriers to Immune Effector Cell Therapy: Rapid Disease Progression, Concern for Toxicity, and Lack of Appropriate Trials Drive Non-Receipt after Referral at a Large Academic Center

Yannis K. Valtis, Kuo-Kai Chin, Meira Yisraeli Salman, Leora Boussi, Briana Cadzin, Carina Mcloughlin, Elizabeth Cathcart, Paul Davis, Chelsea Brooklyn, Todd Goldstein, Christopher Famulare, Gunjan L. Shah, Moneeza Walji, Alexander P. Boardman, Roni Shouval, Eytan M. Stein, Sham Mailankody, Maria Lia Palomba, Gilles Salles, Sergio Giralt, Miguel Angel Perales, Jae H. Park
Journal: Blood
Blood (2024) 144 (Supplement 1): 781.
https://doi.org/10.1182/blood-2024-200915
Published: 2024
Journal Articles

A Single-Cell Atlas of Classical Mantle Cell Lymphoma Reveals Paired Tumor-Immune Malignant States Correlating with Prognosis

Amira Marouf, Sneha Mitra, Irem Isgor, Ashlee Joseph, Jahan Rahman, Ya-Hui Lin, Meril Takizawa, Ronan Chaligne, Shenon Sethi, Ahmet Dogan, Sandrine Roulland, Gilles Salles, Christina Leslie, Anita Kumar, Santosha A. Vardhana
Journal: Blood
Blood (2024) 144 (Supplement 1): 234.
https://doi.org/10.1182/blood-2024-206805
Published: 2024
Journal Articles

CAR-Tography: Longitudinal Mapping of CAR-T Toxicities across B-Cell Malignancies Reveals Biologically Distinct and Prognostically Relevant Toxicity Phenotypes

Kai Rejeski, Teng Fei, Alejandro Luna, Mohammad Alhomoud, Yannis K. Valtis, Noriko Nishimura, Marina Gomez-Llobell, Noa Golan Accav, Ofrat Beyar-Katz, Sandeep S. Raj, Magdalena Corona, Alfredo Rivas-Delgado, Hamza Hashmi, Sridevi Rajeeve, Efrat Luttwak, Michael Scordo, Gunjan L. Shah, Maria Lia Palomba, Michael von Bergwelt-Baildon, Marion Subklewe, Abraham Avigdor, Ronit Marcus, Avichai Shimoni, Arnon Nagler, Tsila Zuckerman, Jabour Halloun, Uri Greenbaum, Sham Mailankody, Saad Z. Usmani, Gilles Salles, Jae H. Park, Miguel Angel Perales, Roni Shouval
Journal: Blood
Blood (2024) 144 (Supplement 1): 912.
https://doi.org/10.1182/blood-2024-203520
Published: 2024
Journal Articles

Patterns of Immune Reconstitution and Their Clinical Significance in Aggressive Lymphoma Treated with CAR-T Therapy

Danny Luan, Susan DeWolf, Teng Fei, Sandeep S. Raj, Gunjan L. Shah, Caleb Lareau, Mohammad Alhomoud, Gilles Salles, Alfredo Rivas-Delgado, Kai Rejeski, Jae H. Park, Efrat Luttwak, Alejandro Luna, Magdalena Corona, Evangelos Ntrivalas, Giulio Cassanello, Marina Gomez-Llobell, Allison Parascondola, Michael Scordo, Katharine C. Hsu, Maria Lia Palomba, Miguel Angel Perales, Roni Shouval
Journal: Blood
Blood (2024) 144 (Supplement 1): 2034.
https://doi.org/10.1182/blood-2024-205548
Published: 2024
Journal Articles

Five-Year Analysis of the POLARIX Study: Prolonged Follow-up Confirms Positive Impact of Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (Pola-R-CHP) on Outcomes

Gilles Salles, Franck Morschhauser, Laurie H. Sehn, Alex F. Herrera, Jonathan W. Friedberg, Marek Trněný, Georg Lenz, Jeff P. Sharman, Charles Herbaux, John M. Burke, Matthew Matasar, Graham P. Collins, Yuqin Song, Antonio Pinto, Shinya Rai, Koji Izutsu, Calvin Lee, Saibah Chohan, Matthew Sugidono, Yanwen Jiang, Connie Lee Batlevi, Mark Yan, Jamie Hirata, Hervé Tilly, Christopher R. Flowers
Journal: Blood
Blood (2024) 144 (Supplement 1): 469.
https://doi.org/10.1182/blood-2024-197938
Published: 2024
Journal Articles

Single-Agent Mosunetuzumab Produces High Complete Response Rates in Patients with Newly Diagnosed Follicular Lymphoma: Primary Analysis of the Mithic-FL1 Trial

Lorenzo Falchi, Michelle Okwali, Alexandra Ferreira Lopes, Paul A. Hamlin, Jennifer Kimberly Lue, Paola Ghione, Colette Owens, Pallawi Torka, Anita Kumar, Raphael Steiner, Zachary D. Epstein-Peterson, Maria Lia Palomba, Robert Stuver, Ariela Noy, Anastasia Martinova, Lauren Wood, Clare Grieve, Walter Ramos Amador, Santosha A. Vardhana, Andrew D. Zelenetz, Lori A. Leslie, Joseph L. Roswarski, Kieron Dunleavy, Andre Goy, Gilles Salles
Journal: Blood
Blood (2024) 144 (Supplement 1): 340.
https://doi.org/10.1182/blood-2024-205046
Published: 2024
Journal Articles

Multicenter Phase II Trial of Zanubrutinib, Obinutuzumab, and Venetoclax (BOVen) in Treatment-Naïve Chronic Lymphocytic Leukemia: 5-Year Follow up, Retreatment Outcomes, and Impact of MRD Kinetics (ΔMRD400)

Jacob D. Soumerai, Ahmet Dogan, Venkatraman Seshan, Kelsey Leigh Flaherty, Natalie Slupe, Jason Carter, Ephraim Hochberg, Jeffrey A. Barnes, Jeremy S. Abramson, Audrey Hamilton, Ariela Noy, Colette Owens, Maria Lia Palomba, Anita Kumar, Lindsey Roeker, Meghan C. Thompson, Ronald W. Takvorian, Zachary D. Epstein-Peterson, Mark Blaine Geyer, Gilles Salles, Robert Stuver, Philip Caron, Prioty Islam, Tamanna Haque, Paola Ghione, Raphael E. Steiner, Pallawi Torka, Kevin A. David, Jennifer Kimberly Lue, Paul A. Hamlin, Alison Moskowitz, Lorenzo Falchi, Julie Haydu, Patrick Connor Johnson, Joanna Mi, Jessica Pendleton, Alyssa Labarre, Rosalba Martignetti, Sean F. Plummer, Maria Chabowska, Walter Ramos Amador, Neena Mahajan, Morgan Choma, Clare Grieve, Rayna N. Garcia, Hailey E. Kelly, Ella Mallinger, James O'Grady, Bernadette Beatty, Michelle Adams, Athina Apazidis, Aileen Cleary Cohen, Mina Shahkarami, Allison P. Jacob, Omar Abdel-Wahab, Andrew D. Zelenetz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1867.
https://doi.org/10.1182/blood-2024-205697
Published: 2024
Journal Articles

Real-World Outcomes of Frontline Polatuzumab and Impact of Frailty in Older Adults with Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

Varun Iyengar, Jessica Chicola, Ashlee Joseph, Michelle Okwali, Regina Truong, Neil Bapodra, Alexander P. Boardman, Philip Caron, Kevin A. David, Zachary D. Epstein-Peterson, Lorenzo Falchi, Paola Ghione, Anita Kumar, Jennifer Kimberly Lue, Efrat Luttwak, Steven Horwitz, Andrew M. Intlekofer, William T. Johnson, Alison Moskowitz, Ariela Noy, Colette Owens, Maria Lia Palomba, Raphael E. Steiner, Robert Stuver, Santosha A. Vardhana, Andrew D. Zelenetz, Gilles Salles, Paul A. Hamlin, Pallawi Torka
Journal: Blood
Blood (2024) 144 (Supplement 1): 2336.
https://doi.org/10.1182/blood-2024-202741
Published: 2024
Journal Articles

Single-Cell Atlas of Diffuse Large B-Cell Lymphoma Reveals Integrated Malignant B Cell and Tumor Microenvironment Characteristics Associated with Clinical Response

Sabrina Baaklini, Alexandre Sarrabay, Adrien Mazuel, Bertrand Escaliere, Chuang Dong, Camille Barthelemy, Laurine Gil, Laila Dahbi, Noushin Mossadegh-Keller, Nathalie Van Acker, Pauline Gravelle, Jean-Marc Navarro, Caroline Huber, Romain Fenouil, Romane Trombetta, Marine Pujol, Philippe Gaulard, Benjamin Riviere, Peggy Dartigues, Francesco Llamas Gutierrez, Celine Pangault, Fabrice Jardin, François Lemonnier, Gilles Salles, Corinne Haioun, Gabriel Brisou, Matthew E. Stokes, Sahil Seth, Maria Ortiz Estevez, Camille Laurent, Lionel Spinelli, Mark Kaplan, C. Chris Huang, Anita K. Gandhi, Bertrand Nadel, Sandrine Roulland, Pierre Milpied
Journal: Blood
Blood (2024) 144 (Supplement 1): 1597.
https://doi.org/10.1182/blood-2024-209815
Published: 2024
Journal Articles

A Proof-of-Principle of Split-Course Bridging Radiotherapy (SC-BRT) Prior to CAR T-Cell Therapies for Relapsed or Refractory B-Cell Lymphomas: A Phase 1a Pilot Cohort

Brandon S. Imber, Anna Brosoff, Emma Roszak, Devin McAvoy, Kinga K. Hosszu, Alexander P. Boardman, Parastoo B Dahi, Gunjan L. Shah, Michael Scordo, Jae H. Park, Miguel-Angel Perales, Gilles Salles, Maria Lia Palomba, Joachim Yahalom
Journal: Blood
Blood (2024) 144 (Supplement 1): 3128.
https://doi.org/10.1182/blood-2024-210156
Published: 2024
Journal Articles

Tumor Determinants of Response to CAR-T Therapy in Relapsed or Refractory Mantle Cell Lymphoma

Zachary D. Epstein-Peterson, Christine E. Ryan, Sean M. Devlin, Noa Golan Accav, Abraham Avigdor, Magdalena Corona, Ivetta Danylesko, Jamie Dela Cruz, Andre Goy, Caron A. Jacobson, Ofrat Beyar Katz, Hazim Khatib, Anita Kumar, Lori A. Leslie, Alejandro Luna, Ronit Marcus, Reid W. Merryman, Miguel Angel Perales, Alfredo Rivas-Delgado, Gilles Salles, Michael Scordo, Inbal Sdayoor, Gunjan L. Shah, Noga Shem-Tov, Avichai Shimoni, Nataly Vahaba, Ronit Yerushalmi, Andrew D. Zelenetz, Maria Lia Palomba, Andrew Ip, Roni Shouval
Journal: Blood
Blood (2024) 144 (Supplement 1): 4393.
https://doi.org/10.1182/blood-2024-193091
Published: 2024
Journal Articles

Genomic Characterization and Classification of BCL6 Rearranged Follicular Lymphomas

Anu Amallraja, Gunes Gundem, Dylan Domenico, Juan E Arango Ossa, Umut Aypar, Jeeyeon Baik, Michael Kluk, Shenon Sethi, Katherine Lopez, David A. Qualls, Gilles Salles, Elli Papaemmanuil, Pallavi Galera, Ahmet Dogan
Journal: Blood
Blood (2024) 144 (Supplement 1): 1589.
https://doi.org/10.1182/blood-2024-203770
Published: 2024
Journal Articles

Minimal Residual Disease (MRD)-Adapted Duration of Front-Line Venetoclax and Obinutuzumab Treatment for Fit Patients with Chronic Lymphocytic Leukemia (CLL)

Lindsey Roeker, Anthony R. Mato, Andrew D. Zelenetz, Jae H. Park, Mark Blaine Geyer, Andriy Derkach, David Nemirovsky, Prioty Islam, Lorenzo Falchi, Maria Lia Palomba, Anita Kumar, Gilles Salles, Jennifer Kimberly Lue, Aaron D. Goldberg, Deborah M. Stephens, Victoria Duffy, Gail Panton, Dianna Tyznar, Colleen Dorsey, Dhara Soni, Claire Hutzler, Lauren Nogan, Alexandra Allen, Tenzin Nyima, Thu Quynh Nguyen, Monica Shah, Tamotha R Cook, Jennifer Abillar-Wright, Jamila Brutus, Carissa Laudati, Bejal Kikani, Catherine C Coombs, Michael R. Silvestrone, Christopher E. Jensen, Bita Fakhri, Meghan C. Thompson
Journal: Blood
Blood (2024) 144 (Supplement 1): 1010.
https://doi.org/10.1182/blood-2024-203807
Published: 2024
Journal Articles

Angioimmunoblastic Versus Non-Angioimmunoblastic Nodal T-Follicular Helper Cell Lymphomas: Single Center Retrospective Analysis on 208 Cases

Benedetta Sordi, Ozgur Can Eren, Nivetha Ganesan, Varun Iyengar, Robert Stuver, William T. Johnson, Alison Moskowitz, Paola Ghione, Natasha Galasso, Ellie Casper, Tiffany Chang, Helen Hancock, Theresa Davey, Alexander P. Boardman, Philip Caron, Kevin A. David, Lorenzo Falchi, Paul A. Hamlin, Andrew M. Intlekofer, Anita Kumar, Efrat Luttwak, Ariela Noy, Colette Owens, Maria Lia Palomba, Gilles Salles, Raphael E. Steiner, Pallawi Torka, Santosha A. Vardhana, Ahmet Dogan, Steven Horwitz, Zachary D. Epstein-Peterson
Journal: Blood
Blood (2024) 144 (Supplement 1): 4451.
https://doi.org/10.1182/blood-2024-210657
Published: 2024
Journal Articles

Pembrolizumab and Involved Site Radiation Therapy Alone As an Alternative to Transplant in Patients with Localized Failure Following Chemotherapy for Hodgkin Lymphoma: A Prospective Multicenter Phase II Study

Alexandra Dreyfuss, Nivetha Ganesan, Alvaro J Alencar, Alexander P. Boardman, Philip Caron, Tiffany Chang, Theresa Davey, Kevin A. David, Ahmet Dogan, Zachary D. Epstein-Peterson, Lorenzo Falchi, Beatrice Fregonese, Paola Ghione, Paul A. Hamlin, Steven Horwitz, Brandon S. Imber, Andrew M. Intlekofer, Derek Isrow, Erel Joffe, William T. Johnson, Anita Kumar, Michael Lariviere, Jennifer Kimberly Lue, Efrat Luttwak, Michael McNicholas, Zachary Moore, Brittney Munayirji, Ariela Noy, Colette Owens, Maria Lia Palomba, Jaldhi Patel, John P Plastaras, Alayna M. Santarosa, Heiko Schoder, Gunjan L. Shah, Raphael E. Steiner, Robert Stuver, Jakub Svoboda, Pallawi Torka, Santosha A. Vardhana, Andrew D. Zelenetz, Gilles Salles, Joachim Yahalom, Craig H. Moskowitz, Alison Moskowitz
Journal: Blood
Blood (2024) 144 (Supplement 1): 4434.
https://doi.org/10.1182/blood-2024-210689
Published: 2024
Journal Articles

Improved Outcomes for Primary Refractory Classical Hodgkin Lymphoma: A Retrospective Analysis

Alayna M. Santarosa, Nivetha Ganesan, Tiffany Chang, Kelly Hannigan, Ellie Casper, Gunjan L. Shah, Alexander P. Boardman, Philip Caron, Kevin A. David, Ahmet Dogan, Zachary D. Epstein-Peterson, Lorenzo Falchi, Paola Ghione, Paul A. Hamlin, Steven Horwitz, Andrew M. Intlekofer, William T. Johnson, Ariel Krivisky, Anita Kumar, Jennifer Kimberly Lue, Efrat Luttwak, Ariela Noy, Colette Owens, Maria Lia Palomba, Gilles Salles, Heiko Schoder, Raphael E. Steiner, Robert Stuver, Pallawi Torka, Santosha A. Vardhana, Joachim Yahalom, Andrew D. Zelenetz, Craig H. Moskowitz, Alison Moskowitz
Journal: Blood
Blood (2024) 144 (Supplement 1): 4429.
https://doi.org/10.1182/blood-2024-203857
Published: 2024
Journal Articles

Very Low Dose Radiotherapy (VLDRT) with 4 Gy for Potentially-Curable Indolent Non-Hodgkin Lymphomas

Nikhil P. Mankuzhy, Brandon S. Imber, Paige Pammer, Beatrice Fregonese, Adriana Cajo, Gustav Cederquist, Alexandra Dreyfuss, Kaitlyn Lapen, Roshal R. Patel, Zachary R. Moore, Carla Hajj, Gilles Salles, Joachim Yahalom
Journal: Blood
Blood (2024) 144 (Supplement 1): 3040.
https://doi.org/10.1182/blood-2024-208916
Published: 2024