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Journal Articles

Preclinical Efficacy and Mechanism for a Novel BTK-Protacs Against Mantle Cell Lymphoma

Yue Fei, Xiaohui Wang, Shangzhe Yu, Yixin Yao, Guisen Zhao, Xianhuo Wang, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2267.
https://doi.org/10.1182/blood-2023-185275
Published: 2023
Journal Articles

YAP1-Dependent Promotion of Downstream Transcription through BRD4 Mediates Selinexor Resistance in Diffuse Large B-Cell Lymphoma

Xiaoxuan Wang, Yidan Zhang, Xianyou Xia, Yixin Yao, Xudong Wu, Xianhuo Wang, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2823.
https://doi.org/10.1182/blood-2023-185242
Published: 2023
Journal Articles

Time to Lymphoma Treatment within 24 Months in Watchful Waiting Follicular Lymphoma Defines Patients at High Risk for Progression: A Multicenter Analysis

Fenghua Gao, Jing Liu, Jiesong Wang, Lihong Liu, Zhiming Li, Yuqin Song, Xudong Zhang, Hui Zhou, Xiuhua Sun, Wei Zhang, Bing Xu, Liping Su, Wen Shujuan, Rong Tao, Ou Bai, Qingyuan Zhang, Liqun Zou, Xianhuo Wang, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4417.
https://doi.org/10.1182/blood-2023-174308
Published: 2023
Journal Articles

Indirect Comparison of Efficacy of Zanubrutinib Versus Orelabrutinib in Patients with Relapsed or Refractory Mantle Cell Lymphoma (R/R MCL): An Updated Analysis with Long-Term Follow up

Yuqin Song, Keshu Zhou, Dengju Li, Jianda Hu, Dehui Zou, Sujun Gao, Haiyan Yang, Huilai Zhang, Jie Ji, Wei Xu, Ru Feng, Jie Jin, Fangfang Lyu, Cheng Fang, Sheng Xu, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1682.
https://doi.org/10.1182/blood-2023-181352
Published: 2023
Journal Articles

Development and Validation of a Machine-Learning Model to Predict POD24 Risk of Follicular Lymphoma

Jie Zha, Qinwei Chen, Wei Zhang, Hongmei Jing, Jingjing Ye, Haifeng Yu, Shuhua Yi, Caixia Li, Zhong Zheng, Wei Xu, Zhifeng Li, Lingyan Ping, Xiaohua He, Liling Zhang, Ying Xie, Feili Chen, Xiuhua Sun, Liping Su, Huilai Zhang, Zhijuan Lin, Haiyan Yang, Weili Zhao, Lugui Qiu, Zhiming Li, Yuqin Song, Bing Xu
Journal: Blood
Blood (2023) 142 (Supplement 1): 3048.
https://doi.org/10.1182/blood-2023-182812
Published: 2023
Journal Articles

A Prospective Multicenter Phase II Study of Orelabrutinib-Lenalidomide-Rituximab (OLR) in Patients with Untreated Mantle Cell Lymphoma (MCL) in China (POLARIS Study): Preliminary Analysis on Efficacy, Safety, Mutation Spectrum and Impact of Mutation Profiling on Treatment Responses

Huilai Zhang, Liping Su, Lihong Liu, Ou Bai, Zheng Song, Zhiqiang Zhao, Cuiying He, Qiang Guo, Xianhuo Wang, Wei Li, Lihua Qiu, Lanfang Li, Shiyong Zhou, Yue Fei, Xiaohui Wang, Bin Meng
Journal: Blood
Blood (2023) 142 (Supplement 1): 736.
https://doi.org/10.1182/blood-2023-178509
Published: 2023
Journal Articles

Health-Related Quality of Life and Symptoms in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma Treated with Odronextamab Monotherapy in the Phase 2 ELM-2 Study

Elzbieta Iskierka-Jazdzewska, Won Seog Kim, Seok-Goo Cho, Tae Min Kim, Isidro Jarque, Tadeusz Robak, Michelle Poon, H. Miles Prince, Sung Yong Oh, Francesca Lim, Cecilia Carpio, Tran-Der Tan, Sabarish Ayyappan, Antonio Gutiérrez, Huilai Zhang, Junning Cao, Mingzhi Zhang, Benoit Tessoulin, Jingjin Li, Cristina Ivanescu, Matthew Reaney, Aafia Chaudhry, Hesham Mohamed, Srikanth Ambati, James Harnett, Lei Chi, Jan Walewski
Journal: Blood
Blood (2023) 142 (Supplement 1): 4504.
https://doi.org/10.1182/blood-2023-180743
Published: 2023
Journal Articles

Integrative Genomic and Transcriptomic Analysis Reveals Genetic Alterations Associated with the Early Progression of Follicular Lymphoma

Fenghua Gao, Hengqi Liu, Xianhuo Wang, Yixin Yao, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 3022.
https://doi.org/10.1182/blood-2023-174182
Published: 2023
Journal Articles

CD58 Genetic Alterations and Its Contribution to Upregulation of PD-L1 and IDO Via LYN/CD22/SHP1 Axis in DLBCL

Xiyue Xu, Qingpei Guan, Lanfang Li, Lihua Qiu, Zhengzi Qian, Shiyong Zhou, Yixin Yao, Xianhuo Wang, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 524.
https://doi.org/10.1182/blood-2023-188468
Published: 2023
Journal Articles

Azacitidine for Injection Combined with Chidamide in Relapsed/Refractory Peripheral T-Cell Lymphoma: A Phase I Study

Jingwei Yu, Yaxiao Lu, Yixin Yao, Xianming Liu, Lanfang Li, Zhengzi Qian, Lihua Qiu, Shiyong Zhou, Xianhuo Wang, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 3076.
https://doi.org/10.1182/blood-2023-188801
Published: 2023
Journal Articles

Anti-Btla Antibody Tifcemalimab As a Single Agent or in Combination with Toripalimab in Relapsed/Refractory Lymphomas

Yuqin Song, JUN MA, Yan Xie, Huilai Zhang, Zhigang Peng, Yuerong Shuang, Fei Li, Yufu Li, Haiyan Yang, Xiuhua Sun, Liqun Zou, Yunhong Huang, Weili Zhao, Wenrong Huang, Hui Zhou, Mingying Liu, Weiwei Wang, Jing Xu, Yajie Wang, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4458.
https://doi.org/10.1182/blood-2023-181385
Published: 2023
Journal Articles

Final Analysis of the Phase 2 ELM-2 Study: Odronextamab in Patients with Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

Sabarish Ayyappan, Won Seog Kim, Tae Min Kim, Jan Walewski, Seok-Goo Cho, Isidro Jarque, Elzbieta Iskierka-Jazdzewska, Michelle Poon, Sung Yong Oh, Francesca Lorraine Wei Inng Lim, Cecilia Carpio, Tran-Der Tan, Antonio Gutiérrez, Huilai Zhang, Junning Cao, Mingzhi Zhang, Benoit Tessoulin, Jingjin Li, Melanie Ufkin, Saleem Shariff, Lei Chi, Aafia Chaudhry, Hesham Mohamed, Srikanth Ambati, H. Miles Prince
Journal: Blood
Blood (2023) 142 (Supplement 1): 436.
https://doi.org/10.1182/blood-2023-179818
Published: 2023
Journal Articles

Treatment of Relapsed/Refractory Hgbcl and Bukitt's Lymphoma with c-Myc Rearrangement: A Multi-Center, Open-Label, Phase 2 Study of PC-002 (SepB), a First-in-Class Deubiquitinase Inhibitor Inducing Myc Degradation

Sung-Soo Yoon, Zhiming Li, Keshu Zhou, Xiaoxi Zhou, Ye Guo, Huilai Zhang, Ki-Seong Eom, Seok Jin Kim, Sung Yong Oh, Sung-Nam Lim, Hagop Youssoufian, Vernon Jiang, Zhanchun Huang, Georgina Kilfoil, Xin Wang, Zhixiang Cao, Xiang LI, Yihai Lin, Alexander Wu, Yiyou Chen, Yuqin Song
Journal: Blood
Blood (2023) 142 (Supplement 1): 1754.
https://doi.org/10.1182/blood-2023-190995
Published: 2023
Journal Articles

C-CAR039, a Novel Anti-CD20/CD19 Bi-Specific CAR T-Cell Therapy Shows Deep and Durable Clinical Benefits in Patients with Relapsed or Refractory (r/r) B-Cell Non-Hodgkin Lymphoma (B-NHL) in Long Term Follow up

Ping Li, Wen-Juan Yu, Lili Zhou, Min Yang, Shiguang Ye, Judy Zhu, Jiaqi Huang, Yan Zhang, Lanfang Li, Jing Zhao, Kevin Zhu, Jing Li, Chengxiao Zheng, Liping Lan, Hui Wan, Yihong Yao, Huilai Zhang, Daobin Zhou, Jie Jin, Aibin Liang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1025.
https://doi.org/10.1182/blood-2023-182817
Published: 2023
Journal Articles

Pirtobrutinib, a Non-Covalent (reversible) BTK Inhibitor, in Mantle Cell Lymphoma Patients Previously Treated with a Covalent BTK Inhibitor: Results from a China Phase 2 Study

Yuqin Song, Shuhua Yi, Haiyan Yang, Ru Feng, Huiqiang Huang, Qingyuan Zhang, Yanyan Liu, Ye Guo, Huilai Zhang, Liling Zhang, Yijiao Qian, JianKun Zhu, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 3636.
https://doi.org/10.1182/blood-2023-173287
Published: 2023
Journal Articles

A Prospective Phase II Study of Radiotherapy Followed By Tiselizumab Combined with R-CHOP in the Untreated Follicular Lymphoma Patients with Bulky Disease in China

Wei Li, Ximei Zhang, Fenghua Gao, Yixin Yao, Xianhuo Wang, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1687.
https://doi.org/10.1182/blood-2023-185752
Published: 2023
Journal Articles

Golidocitinib in Treating Refractory or Relapsed Peripheral T- Cell Lymphoma: Full Analysis of the Multinational Pivotal Study Results (JACKPOT8)

Yuqin Song, Luis Malpica, Qingqing Cai, Weili Zhao, Keshu Zhou, Jianqiu Wu, Huilai Zhang, Kaiyang Ding, Yao Liu, Zengjun Li, Neha Mehta-Shah, Liling Zhang, Meifang Zheng, Jie Jin, Haiyan Yang, Yuerong Shuang, Dok Hyun Yoon, Sujun Gao, Wenyu Li, Zhimin Zhai, Liqun Zou, Yaming Xi, Youngil Koh, Fei Li, Miles Prince, Hui Zhou, Lie Lin, Hui Liu, Zhenfan Yang, Won Seog Kim, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 305.
https://doi.org/10.1182/blood-2023-172962
Published: 2023
Journal Articles

Polatuzumab vedotin in previously untreated DLBCL: an Asia subpopulation analysis from the phase 3 POLARIX trial

Clinical Trials & Observations
Yuqin Song, Hervé Tilly, Shinya Rai, Huilai Zhang, Jie Jin, Hideki Goto, Yasuhito Terui, Ho-Jin Shin, Won Seog Kim, Junning Cao, Jifeng Feng, Hyeon Seok Eom, Tae Min Kim, Xavier Cheng-Hong Tsai, Jyh-Pyng Gau, Hideo Koh, Liling Zhang, Yongping Song, Yu Yang, Wei Li, He Huang, Kiyoshi Ando, Jeff P. Sharman, Laurie H. Sehn, Lilian Bu, Xin Wang, Yanwen Jiang, Jamie Hirata, Calvin Lee, Jun Zhu, Koji Izutsu
Journal: Blood
Blood (2023) 141 (16): 1971–1981.
https://doi.org/10.1182/blood.2022017734
Published: 2023
Includes: Supplemental data
Journal Articles

Combination of Baseline Total Metabolic Tumor Volume Measured on FDG-PET/CT, ECOG Performance Status and β2-Microglobulin Have a Robust Predictive Value in Patients with Primary Breast Lymphoma

Peiqi Zhao, Lei Zhu, Lanfang Li, Shiyong Zhou, Lihua Qiu, Kai Fu, Huilai Zhang
Journal: Blood
Blood (2022) 140 (Supplement 1): 3805–3806.
https://doi.org/10.1182/blood-2022-158674
Published: 2022
Journal Articles

Five-Year Results and Overall Survival Update from the Phase 3 Randomized Study Augment: Lenalidomide Plus Rituximab (R 2 ) Vs Rituximab Plus Placebo in Patients with Relapsed/Refractory Indolent Non-Hodgkin Lymphoma

John P. Leonard, Marek Trneny, Fritz Offner, Jiri Mayer, Huilai Zhang, Grzegorz S. Nowakowski, Phillip Scheinberg, Argyrios Gkasiamis, Joanna Mikita-Geoffroy, Everton Rowe, John G. Gribben
Journal: Blood
Blood (2022) 140 (Supplement 1): 561–563.
https://doi.org/10.1182/blood-2022-158631
Published: 2022