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Journal Articles

Ibrutinib Combined with Venetoclax in Patients with Relapsed/Refractory Mantle Cell Lymphoma: Primary Analysis Results from the Randomized Phase 3 Sympatico Study

Michael Wang, Wojciech Jurczak, Marek Trněný, David Belada, Tomasz Wrobel, Nilanjan Ghosh, Mary-Margaret Keating, Tom van Meerten, Ruben Fernandez Alvarez, Gottfried von Keudell, Catherine Thieblemont, Frederic Peyrade, Marc Andre, Marc Hoffmann, Edith Szafer Glusman, Jennifer Lin, James P. Dean, Jutta K. Neuenburg, Constantine S. Tam
Journal: Blood
Blood (2023) 142 (Supplement 2): LBA-2.
https://doi.org/10.1182/blood-2023-191921
Published: 2023
Journal Articles

Risk of Central Nervous System Vs. Systemic Relapse in Patients with Diffuse Large B-Cell Lymphoma Treated with R-CHOP: What Should We Focus on?

Magdalena Klanova, Samuel Hricko, Michal Masar, David Salek, Prokop Vodicka, Natasa Kopalova, Petra Blahovcova, Katerina Benesova, Jozef Michalka, Jan Koren, Andrea Janikova, Marek Trneny
Journal: Blood
Blood (2023) 142 (Supplement 1): 4479.
https://doi.org/10.1182/blood-2023-178208
Published: 2023
Journal Articles

Do the Control Cohorts of Phase III Randomized Trials Reflect the Real-World Results of DLBCL Patients?

Prokop Vodicka, Andrea Janikova, David Belada, Heidi Mocikova, Vit Prochazka, Juraj Duras, Katerina Steinerova, Vit Campr, Katerina Benesova, Samuel Hricko, Alice Sykorova, Petra Blahovcova, Radek Jaksa, Magdalena Klanova, Marek Trněný
Journal: Blood
Blood (2023) 142 (Supplement 1): 4485.
https://doi.org/10.1182/blood-2023-185620
Published: 2023
Journal Articles

Hematopoietic Stem Cell Transplantation for DLBCL: 55,000 Cases from EBMT As a Comparator for CAR T-Cells

Philipp Berning, Ariane Boumendil, Anthony H. Goldstone, Anna Maria Sureda Balari, Peter Dreger, Silvia Montoto, Maud Ngoya, Hervé Finel, Patrice Chevallier, Didier Blaise, Tim Struessmann, Ben Carpenter, Edouard Forcade, Cristina Castilla-Llorente, Marek Trněný, Herve Ghesquieres, Capria Saveria, Catherine Thieblemont, Igor Wolfgang Blau, Ellen Meijer, Annoek E.C. Broers, Anne Huynh, Denis Caillot, Wolf Roesler, Stéphanie Nguyen Quoc, Jörg Bittenbring, Arnon Nagler, Bertram Glass, Norbert Schmitz
Journal: Blood
Blood (2023) 142 (Supplement 1): 441.
https://doi.org/10.1182/blood-2023-184788
Published: 2023
Journal Articles

Plasma Circulating Tumor DNA (ctDNA) as an Alternative to Tissue DNA for Genotyping of DLBCL: Results from the POLARIX Study

Fabrice Jardin, Vibha Raghavan, Samuel Tracy, Sandhya Balasubramanian, Laurie H. Sehn, Christopher R. Flowers, Franck Morschhauser, Alex F. Herrera, Marek Trněný, Jeff P. Sharman, Gilles Salles, Hervé Tilly, Jonathan W. Friedberg, Will Harris, Jamie H. Hirata, Calvin Lee, Yanwen Jiang, Georg Lenz
Journal: Blood
Blood (2023) 142 (Supplement 1): 169.
https://doi.org/10.1182/blood-2023-178564
Published: 2023
Journal Articles

Diagnosis to Treatment Interval Is the Most Significant Prognostic Factor Compared to Symptoms to Treatment As Well As to Contact to Treatment Intervals in DLBCL Patients

Prokop Vodicka, Michal Masar, Magdalena Klanova, Katerina Benesova, Jan Koren, Pavel Klener, Petra Blahovcova, Jitka Dlouha, Sarka Hrabetova, Marek Trněný
Journal: Blood
Blood (2023) 142 (Supplement 1): 4510.
https://doi.org/10.1182/blood-2023-186467
Published: 2023
Journal Articles

Survival Patterns of Non-Randomized Patients in the IELSG37 Study: Deauville Score 4 Is Not Necessarily Associated with Poor Outcome in Primary Mediastinal Lymphoma

Emanuele Zucca, Luca Ceriani, Andrew S. Davies, Giovannino Ciccone, Umberto Ricardi, Alice Di Rocco, Iryna Kryachok, Barbara Botto, Monica Balzarotti, Alessandra Tucci, Vittorio Ruggero Zilioli, Sara Usai, Luca Arcaini, Elsa Pennese, Anna Dabrowska-Iwanicka, Andrés José María Ferreri, Franceso Merli, Wei Li Zhao, David Hodgson, Codruta Ionescu, Luigi Rigacci, Claudia Cellini, Caterina Stelitano, Stefano Volpetti, Carla Minoia, Michele Spina, Alexander Fossa, George Mikhaeel, Kate Cwynarski, Andrea Janikova, Yana Stepanishyna, Mats Jerkeman, Andreas Huettmann, Maria Gomes da Silva, Don A. Stevens, Sally F Barrington, Bogdan Małkowski, Ur Metser, Annibale Versari, Stephane Chauvie, Oreste Bagni, Kelly Cozens, Sonia Perticone, Nicoletta Ielmini, Letizia Deantonio, Jan Walewski, Marek Trneny, Mary Gospodarowicz, Franco Cavalli, Peter Johnson, Maurizio Martelli
Journal: Blood
Blood (2023) 142 (Supplement 1): 1718.
https://doi.org/10.1182/blood-2023-174093
Published: 2023
Journal Articles

Epcoritamab SC + GemOx Leads to High Complete Metabolic Response Rates in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma Ineligible for Autologous Stem Cell Transplant: Updated Results from Epcore NHL-2

Joshua Brody, Judit Mészáros Joergensen, David Belada, Regis T. Costello, Marek Trněný, Umberto Vitolo, David Lewis, Yasmin H. Karimi, Anna Maria Sureda Balari, Marc André, Björn E. Wahlin, Pieternella Lugtenburg, Faith Galderisi, Aqeel Abbas, Yaou Song, Malene Risum, Raul Cordoba
Journal: Blood
Blood (2023) 142 (Supplement 1): 3092.
https://doi.org/10.1182/blood-2023-180246
Published: 2023
Journal Articles

DLBCL Patients' Journey: From Symptoms to Diagnosis

Prokop Vodicka, Michal Masar, Magdalena Klanova, Katerina Benesova, Jan Koren, Pavel Klener, Petra Blahovcova, Sarka Hrabetova, Jitka Dlouha, Marek Trněný
Journal: Blood
Blood (2023) 142 (Supplement 1): 3140.
https://doi.org/10.1182/blood-2023-186207
Published: 2023
Journal Articles

biomarker Driven Strategies for Targeted Elimination of Hypoxia Adapted Lymphoma Cells

Pavel Klener, Jr., Lenka Daumová, Dmitry Kazantsev, Ladislav Anděra, Jiří Petrák, Alexandra Dolníková, Nardjas Bettazová, Petra Kovaříková, Nicol Renešová, Liliana Tušková, Dana Sovilj, Marek Trněný, Magdalena Klanova, Ondrej Havránek
Journal: Blood
Blood (2023) 142 (Supplement 1): 4374.
https://doi.org/10.1182/blood-2023-182705
Published: 2023
Journal Articles

Single Cell RNA Sequencing Enables Identification of Mantle Cell Lymphoma Subclones with Drug-Resistant Profiles Already at Diagnosis and May be Used for Therapy Prognostication and Personalization

Dmitry Kazantsev, Magdalena Klanova, Michal Kolář, Robert Ivánek, Marek Trněný, Pavel Klener, Jr.
Journal: Blood
Blood (2023) 142 (Supplement 1): 3004.
https://doi.org/10.1182/blood-2023-185925
Published: 2023
Journal Articles

Deciphering the Clinical Benefit of Pola-R-CHP versus R-CHOP in Different Genetic Subtypes Beyond Cell of Origin in the POLARIX Study

Franck Morschhauser, Wilfred Leung, Vibha Raghavan, Georg Lenz, Fabrice Jardin, Alex F. Herrera, Laurie H. Sehn, Jeff P. Sharman, Christopher R. Flowers, Jonathan W. Friedberg, Marek Trněný, Hervé Tilly, Charles Herbaux, Samuel Tracy, Christopher R. Bolen, Will Harris, Jamie H. Hirata, Calvin Lee, Yanwen Jiang, Gilles Salles
Journal: Blood
Blood (2023) 142 (Supplement 1): 3000.
https://doi.org/10.1182/blood-2023-178623
Published: 2023
Journal Articles

Safety and efficacy of tafasitamab with or without lenalidomide added to first-line R-CHOP for DLBCL: the phase 1b First-MIND study

Clinical Trials & Observations
David Belada, Katerina Kopeckova, Juan Miguel Bergua Burgues, Don Stevens, Marc André, Ernesto Perez Persona, Petra Pichler, Philipp B. Staber, Marek Trneny, Johannes Duell, Maeve Waldron-Lynch, Steve Wagner, Amitava Mukhopadhyay, Maren Dirnberger-Hertweck, John M. Burke, Grzegorz S. Nowakowski
Journal: Blood
Blood (2023) 142 (16): 1348–1358.
https://doi.org/10.1182/blood.2023020637
Published: 2023
Includes: Supplemental data
Journal Articles

BCL-XL Blockage with A1155463 Significantly Increases Efficacy of Venetoclax in Mantle Cell Lymphoma in Vitro and In Vivo

Alexandra Dolníková, Dmitry Kazantsev, Diana Malarikova, Eva Pokorna, Dana Sovilj, Cristina Daniela Kelemen, Ladislav Andera, Marek Trněný, Pavel Klener, Jr.
Journal: Blood
Blood (2022) 140 (Supplement 1): 6383–6384.
https://doi.org/10.1182/blood-2022-170109
Published: 2022
Journal Articles

Inhibition of MAPK-ERK Signaling Pathway Overcomes Microrna-Mediated Ibrutinib Resistance in Mantle Cell Lymphoma

Olga Kersy, Mali Salmon-Divon, Maria Gomes da Silva, Ana Filipa Moita, Jose Cabecadas, Pavel Klener, Jr., Marek Trněný, May Basood, Ofer Shpilberg, Oshrat Hershkovitz-Rokah
Journal: Blood
Blood (2022) 140 (Supplement 1): 3109–3110.
https://doi.org/10.1182/blood-2022-169574
Published: 2022
Journal Articles

Sequencing-Based Analysis of Clonal Evolution of 25 Mantle Cell Lymphoma Patients at Diagnosis and after Failure of Standard Immunochemotherapy

Jana Karolova, Dmitry Kazantsev, Michael Svaton, Liliana Tušková, Kristina Forsterova, Diana Malarikova, Katerina Benesova, Tomáš Heizer, Alexandra Dolníková, Magdalena Klanova, Eva Fronkova, Marek Trněný, Pavel Klener, Jr.
Journal: Blood
Blood (2022) 140 (Supplement 1): 6409–6410.
https://doi.org/10.1182/blood-2022-166069
Published: 2022
Journal Articles

Glofitamab Monotherapy Induces High Complete Response Rates in Patients with Heavily Pretreated Relapsed or Refractory Mantle Cell Lymphoma

Tycel J. Phillips, Michael Dickinson, Franck Morschhauser, Emmanuel Bachy, Michael Crump, Marek Trněný, Nancy L. Bartlett, Jan Zaucha, Tomasz Wrobel, Fritz Offner, Kathryn Humphrey, Linda Lundberg, James Relf, Audrey Filézac de L'Étang, David Carlile, Ben Byrne, Naseer Qayum, Carmelo Carlo-Stella
Journal: Blood
Blood (2022) 140 (Supplement 1): 178–180.
https://doi.org/10.1182/blood-2022-157777
Published: 2022
Journal Articles

Survival of Patients with Primary Mediastinal B-Cell Lymphoma Treated By Immunochemotherapy with or without Radiotherapy

Kamila Polgarova, Andrea Janíková, David Belada, Vit Prochazka, Juraj Ďuraš, Heidi Móciková, Kateřina Steinerová, Vít Campr, Petra Blahovcová, David Zogala, Václav Ptáčník, Marek Trneny
Journal: Blood
Blood (2022) 140 (Supplement 1): 3831–3832.
https://doi.org/10.1182/blood-2022-163113
Published: 2022
Journal Articles

Risk Profiling of Patients with Previously Untreated Diffuse Large B-Cell Lymphoma (DLBCL) By Measuring Circulating Tumor DNA (ctDNA): Results from the POLARIX Study

Alex F. Herrera, Ronald McCord, Patrick Kimes, Fabrice Jardin, Georg Lenz, Marek Trneny, Christopher R. Flowers, Laurie H. Sehn, Gilles Salles, Jeff P. Sharman, Hervé Tilly, Jonathan W. Friedberg, Charles Herbaux, Matthew J. Matasar, Corinne Haioun, Samuel Tracy, Jamie Hirata, Calvin Lee, Yanwen Jiang, Franck Morschhauser
Journal: Blood
Blood (2022) 140 (Supplement 1): 1297–1300.
https://doi.org/10.1182/blood-2022-157559
Published: 2022
Journal Articles

First-Mind: Final Analysis from a Phase Ib, Open-Label, Randomized Study to Assess Safety of Tafasitamab or Tafasitamab + Lenalidomide in Addition to R-CHOP in Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma

Grzegorz S. Nowakowski, Johannes Duell, Katerina Kopeckova, Marek Trneny, Christiane Pott, Mouhamad Khouja, John M. Burke, Maeve Waldron-Lynch, Steve Wagner, Amitava Mukhopadhyay, Derek Blair, David Belada
Journal: Blood
Blood (2022) 140 (Supplement 1): 3731–3733.
https://doi.org/10.1182/blood-2022-163160
Published: 2022