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Ondrej Havranek
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Journal Articles

Can Circulating Tumor DNA Improve the Predictive Value of Interim Response in Patients with Advanced Hodgkin Lymphoma and PET-2 DS3?

Heidi Mocikova, Kristyna Kupcova, Jana Markova, Lubica Gaherova, Maria Maco, Iva Hamova, Adriana Velasova, Alice Sykorova, Pavla Stepankova, Alexandra Kredatusova, Vit Prochazka, Jan Koren, Petr Nehasil, Petra Zemankova, Tomas Kozak, Ondrej Havranek
Journal: Blood
Blood (2024) 144 (Supplement 1): 6193.
https://doi.org/10.1182/blood-2024-210890
Published: 2024
Journal Articles

Vitreous Body Cell Free DNA Sequencing As a Reliable Method for Vitreoretinal Lymphoma Diagnostics

Adriana Velasova, Lucie Dlouha, Iva Hamova, Kristyna Kupcova, Petra Zemankova, Petr Nehasil, Jana Senavova, Katerina Benesova, Petra Svozilkova, Jarmila Heissigerova, Marek Trneny, Ondrej Havranek
Journal: Blood
Blood (2024) 144 (Supplement 1): 2979.
https://doi.org/10.1182/blood-2024-211732
Published: 2024
Journal Articles

Circulating Tumor DNA As a Predictor of Survival of DLBCL Patients in a Daily Practice

Iva Hamova, Prokop Vodicka, Adriana Velasova, Kristyna Kupcova, Petra Zemankova, Petr Nehasil, Anton Tkachenko, Kamila Polgarova, Jana Salkova, Katerina Benesova, Pavel Klener, Marek Trneny, Ondrej Havranek
Journal: Blood
Blood (2024) 144 (Supplement 1): 6235.
https://doi.org/10.1182/blood-2024-211263
Published: 2024
Journal Articles

Exploiting TCF3-Driven Oncogenic Circuits in Burkitt Lymphoma

Jens Löber, Nazli Serin, Salaheddine Ali, Petra Vockova, Marek Werth, Julia Richter, Marieluise Kirchner, Shashwat Sahay, Hanibal Bohnenberger, Kristyna Kupcova, Rebecca Wurm-Kuczera, Claudia Chapuy, Kirsty Wienand, Kamil Bojarczuk, Viviane Grewe, Jenniffer Günther, Naveed Ishaque, Philipp Ströbel, Philipp Mertins, Ondrej Havranek, Wolfram Klapper, Ulrich Keller, Tomas Etrych, Pavel Klener, Björn Chapuy
Journal: Blood
Blood (2024) 144 (Supplement 1): 230.
https://doi.org/10.1182/blood-2024-209616
Published: 2024
Journal Articles

biomarker Driven Strategies for Targeted Elimination of Hypoxia Adapted Lymphoma Cells

Pavel Klener, Jr., Lenka Daumová, Dmitry Kazantsev, Ladislav Anděra, Jiří Petrák, Alexandra Dolníková, Nardjas Bettazová, Petra Kovaříková, Nicol Renešová, Liliana Tušková, Dana Sovilj, Marek Trněný, Magdalena Klanova, Ondrej Havránek
Journal: Blood
Blood (2023) 142 (Supplement 1): 4374.
https://doi.org/10.1182/blood-2023-182705
Published: 2023
Journal Articles

Role of Autoantigen Induced-B-Cell Receptor Internalization and Its Inhibition for the Biology and Survival of Diffuse Large B-Cell Lymphoma (DLBCL) Cells

Patryk Gorniak, Ondrej Havránek, Anna Polak, Przemyslaw Juszczynski
Journal: Blood
Blood (2023) 142 (Supplement 1): 4141.
https://doi.org/10.1182/blood-2023-187046
Published: 2023
Journal Articles

Cyclin-Dependent Kinase 4/6 Inhibitor Palbociclib Synergizes with BH3-Mimetics in Experimental Models of Relapsed/Refractory Mantle Cell Lymphoma

Diana Malarikova, Radek Jorda, Alexandra Dolníková, Ondrej Havranek, Eva Pokorna, Dmitry Kazantsev, Dana Sovilj, Karel Helman, Magdalena Klanova, Ladislav Andera, Miroslav Strnad, David Chiron, Marek Trneny, Pavel Klener, Jr.
Journal: Blood
Blood (2022) 140 (Supplement 1): 5996–5997.
https://doi.org/10.1182/blood-2022-168617
Published: 2022
Journal Articles

Antigen-Independent, Autonomous B-Cell Receptor Signaling in Diffuse Large B-Cell Lymphoma

Janneke A. Eken, Marvyn T. Koning, Julieta H. Sepulveda Yanez, Cornelis A.M. van Bergen, Edwin Quinten, Kristyna Kupcova, Ondrej Havranek, Ruben A.L. De Groen, Joost S.P. Vermaat, Daphne de Jong, Philip Kluin, Arjen Cleven, Hassan Jumaa, Hendrik Veelken
Journal: Blood
Blood (2022) 140 (Supplement 1): 6444–6445.
https://doi.org/10.1182/blood-2022-159420
Published: 2022
Journal Articles

Combinatorial PI3K/AKT Pathway Inhibition As a Therapeutic Approach in Diffuse Large B-Cell Lymphoma

Kristyna Kupcova, Jana Senavova, Vaclav Herman, Tereza Chrbolkova, Iva Ondeckova, Mariana Pacheco-Blanco, Ondrej Havranek
Journal: Blood
Blood (2022) 140 (Supplement 1): 3149–3150.
https://doi.org/10.1182/blood-2022-166121
Published: 2022
Journal Articles

Is It Better to Start Treatment with ABVD and Continue with PET2-Adapted Approach or Should We Use 2 Cycles of Beacopp Escalated and 2 Cycles of ABVD and Irradiation in Early Unfavorable Hodgkin Lymphoma?

Heidi Mocikova, Jana Markova, Lubica Gaherova, Maria Maco, Alice Sykorova, David Belada, Marie Lukasova, Vit K Prochazka, Katarina Hradska, Juraj Ďuraš, Ondrej Havranek, Tomas Kozak
Journal: Blood
Blood (2021) 138 (Supplement 1): 4539.
https://doi.org/10.1182/blood-2021-148363
Published: 2021
Journal Articles

Cyclin-Dependent Kinase 4/6 Inhibitor Palbociclib Synergizes with BCL2 Inhibitor Venetoclax in Experimental Models of Chemotherapy Refractory Mantle Cell Lymphoma

Diana Malarikova, Radek Jorda, Alexandra Dolnikova, Eva Pokorna, Dmitry Kazantsev, Ondrej Havranek, Karel Helman, Magdalena Klanova, Miroslav Strnad, Marek Trneny, Pavel Klener, Jr.
Journal: Blood
Blood (2021) 138 (Supplement 1): 1203.
https://doi.org/10.1182/blood-2021-150517
Published: 2021
Journal Articles

Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies

Maciej Szydlowski, PhD, Filip Garbicz, MD, Ewa Jabłońska, PhD, Patryk Górniak, PhD, Beata Pyrzynska, PhD, Kamil Bojarczuk, PhD, Dorota Komar, PhD, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Ciećkiewicz, MD PhD, Grzegorz Rymkiewicz, MDPhD, Magdalena Cybulska, DVM, Małgorzata Statkiewicz, Marta Gajewska, PhD, MIchał Mikula, PhD, Aniela Golas, PhD, Joanna Domagała, MSc, Magdalena Winiarska, Agnieszka Graczyk-Jarzynka, Emilia Bialopiotrowicz, PhD, Anna Polak, PhD, Joanna Barankiewicz, MD, Bartosz Pula, MDPhD, Michael R Green, PhD, Dominika Nowis, MD PhD, Jakub Golab, Andrea Massimiliano Tomirotti, PhD, Krzysztof Brzózka, PhD, Mariana Pacheco-Blanco, Kristyna Kupcova, Ondrej Havranek, MDPhD, Bjoern Chapuy, MDPhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-134778
Published: 2020
Journal Articles

Overcoming NOTCH1-Driven Chemoresistance in T-Cell Acute Lymphoblastic Leukemia Via Metabolic Intervention with Oxphos Inhibitor

Natalia Baran, PhDMD, Alessia Lodi, PhD, Yogesh Dhungana, PhD, Shannon RENEE Sweeney, PhD, Pandey Renu, PhD, Shelley Herbrich, PhD, Fieke W Hoff, BSc, Anna Skwarska, PhD, Mecit Kaplan, MS, Vinitha Mary Kuruvilla, MSc, Antonio Cavazos, MSc, Marc Warmoes, PhD, Shanti Rojas-Sutterlin, PhD, Andre Haman, PhD, Diogo Troggian Veiga, PhD, Ken Furudate, DDM, PhD, Helen Ma, MS, Karine Harutyunyan, PhD, Wentao Yang, Mihai Gagea, MDPhD, Di Du, PhD, May Daher, Luciana Melo Garcia, MD, Sujan Piya, PhD, Vivian Ruvolo, MS, Sriram Shanmugavelandy, Ningping Feng, PhD, Jason P Gay, MS, Ondrej Havranek, MDPhD, Jared Henderson, MS, Katarzyna Tomczak, PhD, Marcin Kaminski, PhD, Daniel Herranz, PharmD, Adolfo Ferrando, MD, PhD, Elias Jabbour, MD, Maria E Di Francesco, PhD, David T. Teachey, MD, Terzah M. Horton, MD PhD, Katayoun Rezvani, MD PhD, Jun J. Yang, PhD, Steven M. Kornblau, MD, Eric Davis, MD, Koichi Takahashi, MD PhD, Michael Andreeff, MD PhD, Joseph R Marszalek, PhD, Philip Lorenzi, PhD, Jiyang Yu, PhD, Stefano Tiziani, PhD, Trang Hoang, PhD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–20.
https://doi.org/10.1182/blood-2020-136801
Published: 2020
Journal Articles

Co-Targeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal In Vivo in Relapsed Refractory Mantle Cell Lymphoma with Complex Karyotype Changes

Pavel Klener, Jr., Marek Trněný, Ladislav Andera, MSc, PhD, Zuzana Nahacka, MSc, Magdalena Klanova, MD PhD, Jana Karolova, MD, Michael Svaton, MD, Ondrej Havranek, MDPhD, Jan Soukup, MD, Zuzana Zemanova, PhD, Diana Tuskova, MD, Eva Pokorna, Kristina Forsterova, MSc, PhD, Petra Vockova, MD, Eva Fronkova, MD PhD, Dana Prukova, Ing, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 42.
https://doi.org/10.1182/blood-2018-99-112437
Published: 2018
Journal Articles

Tonic B-cell receptor signaling in diffuse large B-cell lymphoma

Ondrej Havranek, Jingda Xu, Stefan Köhrer, Zhiqiang Wang, Lisa Becker, Justin M. Comer, Jared Henderson, Wencai Ma, John Man Chun Ma, Jason R. Westin, Dipanjan Ghosh, Nicholas Shinners, Luhong Sun, Allen F. Yi, Anusha R. Karri, Jan A. Burger, Tomasz Zal, R. Eric Davis
Journal: Blood
Blood (2017) 130 (8): 995–1006.
https://doi.org/10.1182/blood-2016-10-747303
Published: 2017
Includes: Multimedia, Supplemental data
Journal Articles

Molecular Aspects of Tonic B-Cell Receptor Signaling in Diffuse Large B-Cell Lymphoma Provide Biomarkers and Targets for Specific Inhibition

Ondrej Havranek, MD PhD, Jingda Xu, PhD, Stefan Koehrer, MD, Zhiqiang Wang, PhD, Justin M Comer, Lisa Becker, Allen F Yi, Jan A. Burger, MD PhD, Jason R. Westin, MD, Tomasz Zal, PhD, Richard Eric Davis, MD
Journal: Blood
Blood (2016) 128 (22): 779.
https://doi.org/10.1182/blood.V128.22.779.779
Published: 2016
Journal Articles

B-Cell Receptor Signaling in Diffuse Large B-Cell Lymphoma: Tonic Alone in the Germinal Center B-Cell Subtype, Plus Self Antigen-Induced in the Activated B-Cell Subtype

Ondrej Havranek, MDPhD, Stefan Koehrer, MD, Jingda Xu, PhD, Lisa Becker, Justin M Comer, Anusha R Karri, Zhiqiang Wang, PhD, Wencai Ma, PhD, Jason R Westin, MD, Tomasz Zal, PhD, Jan A Burger, MD PhD, R Eric Davis, MD
Journal: Blood
Blood (2015) 126 (23): 464.
https://doi.org/10.1182/blood.V126.23.464.464
Published: 2015
Journal Articles

The B-Cell Receptor Is Required for Optimal Viability, Growth, and Chemotherapy Resistance of Diffuse Large B-Cell Lymphoma Cell Lines of the Germinal Center B-Cell Subtype

Ondrej Havranek, MDPhD, Stefan Koehrer, MD, Justin M Comer, Zhiqiang Wang, PhD, Jingda Xu, PhD, Dipanjan Ghosh, PhD, Nicholas Shinners, PhD, Luhong Sun, MD PhD, Wencai Ma, PhD, Jan A Burger, MDPhD, R Eric Davis, MD
Journal: Blood
Blood (2014) 124 (21): 493.
https://doi.org/10.1182/blood.V124.21.493.493
Published: 2014
Journal Articles

Immunoglobulin Heavy Chain (IgH) Knockout Inhibits Proliferation of Pre-BCR + B-Cell Acute Lymphoblastic Leukemia (B-ALL) Via a FOXO1 and MYC Dependent Mechanism

Stefan Koehrer, MD, Ondrej Havranek, MDPhD, R Eric Davis, MD, Felix Seyfried, MD, Greg Coffey, PhD, Ekaterina Kim, MS, Nathalie Y. Rosin, PhD, Elisa ten Hacken, PhD, Ulrich Jäger, MD, Katrina Vanura, PhD, Susan O'Brien, MD, Deborah A. Thomas, MD, Hagop M. Kantarjian, MD, Dipanjan Ghosh, PhD, Zhiqiang Wang, Lüder Hinrich Meyer, MD, Hassan Jumaa, PhD, Jan A. Burger, MDPhD
Journal: Blood
Blood (2014) 124 (21): 287.
https://doi.org/10.1182/blood.V124.21.287.287
Published: 2014
Journal Articles

Integrated Analysis Of Genomic and Gene Expression Profiles In Follicular Lymphoma Reveals Subsets and Driver Genes Of Potential Microenvironmental Importance

Ondrej Havranek, MD PhD, Jason R. Westin, MD, Min Zhang, PhD, Seema Rawal, PhD, Larry W. Kwak, MD, PhD, Sattva S. Neelapu, MD, R. Eric Davis, MD
Journal: Blood
Blood (2013) 122 (21): 2487.
https://doi.org/10.1182/blood.V122.21.2487.2487
Published: 2013