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Journal Articles

Targeting Wnt/β-Catenin and BCL-2, Two Critical Survival Factors, Synergistically Induces Apoptosis in AML Via Rac1-Mediated MCL-1 Inhibition

Xiangmeng Wang, Po Yee Mak, Wencai Ma, Xiaoping Su, PhD, Hong Mu, MD PhD, Wenjing Tao, Michael Andreeff, MD PhD, Bing Z Carter, PhD

Blood (2018) 132 (Supplement 1): 1442.

https://doi.org/10.1182/blood-2018-99-118367

Published: 2018

Journal Articles

Mutational landscape of myelodysplastic/myeloproliferative neoplasm–unclassifiable

Blood (2018) 132 (19): 2100–2103.

https://doi.org/10.1182/blood-2018-05-848473

Published: 2018

Includes: Supplemental data

Journal Articles

C-Reactive Protein Promotes Bone Destruction in Human Myeloma By Stimulating Myeloma Cell Production of Osteolytic Cytokines Via the CD32/FcγRII-p38MAPK-Twist Axis

Jing Yang, PhD, Zhiqiang Liu, PhD, Huan Liu, PhD, Jin He, Jianling Yang, PhD, Pei Lin, MDDM,MDC, Qiang WANG, PhD, Juan Du, PhD MD, Wencai Ma, Richard E Davis, BSPharm, MS, Robert Z. Orlowski, MD PhD, Jian Hou, MD, Qing Yi, MD PhD

Blood (2017) 130 (Supplement 1): 3043.

https://doi.org/10.1182/blood.V130.Suppl_1.3043.3043

Published: 2017

Journal Articles

Tonic B-cell receptor signaling in diffuse large B-cell lymphoma

Ondrej Havranek, Jingda Xu, Stefan Köhrer, Zhiqiang Wang, Lisa Becker, Justin M. Comer, Jared Henderson, Wencai Ma, John Man Chun Ma, Jason R. Westin, Dipanjan Ghosh, Nicholas Shinners, Luhong Sun, Allen F. Yi, Anusha R. Karri, Jan A. Burger, Tomasz Zal, R. Eric Davis

Blood (2017) 130 (8): 995–1006.

https://doi.org/10.1182/blood-2016-10-747303

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

ONC201 Induces p53-Independent Apoptosis and Abrogates Stem Cell Function in Hematological Malignancies By Induction of ATF4 through Integrated Stress Response

Blood (2015) 126 (23): 2051.

https://doi.org/10.1182/blood.V126.23.2051.2051

Published: 2015

Journal Articles

Gene Expression Profiling for Molecular Features of Response in a Phase I Trial of Alisertib Plus Romidepsin for Relapsed/Refractory Aggressive B- and T-Cell Lymphomas

Blood (2015) 126 (23): 2705.

https://doi.org/10.1182/blood.V126.23.2705.2705

Published: 2015

Journal Articles

B-Cell Receptor Signaling in Diffuse Large B-Cell Lymphoma: Tonic Alone in the Germinal Center B-Cell Subtype, Plus Self Antigen-Induced in the Activated B-Cell Subtype

Ondrej Havranek, MDPhD, Stefan Koehrer, MD, Jingda Xu, PhD, Lisa Becker, Justin M Comer, Anusha R Karri, Zhiqiang Wang, PhD, Wencai Ma, PhD, Jason R Westin, MD, Tomasz Zal, PhD, Jan A Burger, MD PhD, R Eric Davis, MD

Blood (2015) 126 (23): 464.

https://doi.org/10.1182/blood.V126.23.464.464

Published: 2015

Journal Articles

Antileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy

Byung-Sik Cho, Zhihong Zeng, Hong Mu, Zhiqiang Wang, Sergej Konoplev, Teresa McQueen, Marina Protopopova, Jorge Cortes, Joseph R. Marszalek, Sheng-Bin Peng, Wencai Ma, R. Eric Davis, Donald E. Thornton, Michael Andreeff, Marina Konopleva

Blood (2015) 126 (2): 222–232.

https://doi.org/10.1182/blood-2015-02-628677

Published: 2015

Includes: Supplemental data

Journal Articles

Mucin 20 (MUC20) Modulates Proteasome Assembly Chaperones through the c-MET Pathway and Is a Biomarker of Proteasome Inhibitor Sensitivity in Myeloma

Huihan Wang, MD, PhD, Veerabhadran Baladandayuthapani, PhD, Heather Yan Lin, PhD, Xiaobin Wang, MD, Bingzong Li, MD, PhD, Xing-Ding Zhang, PhD, Isere Kuiatse, PhD, Hua Wang, PhD, Dongmin Gu, MD, PhD, Liye Zhong, PhD, Wencai Ma, PhD, Richard E. Davis, MD, Robert Z. Orlowski, MD, PhD

Blood (2014) 124 (21): 274.

https://doi.org/10.1182/blood.V124.21.274.274

Published: 2014

Journal Articles

GCS-100 Induces Apoptosis of Acute Myeloid Leukemia Cells By Disrupting Galectin-Mediated Survival Signaling

Richard E. Davis, MD, Vivian R Ruvolo, MA, Zhiqiang Wang, Wencai Ma, PhD, Wendy D. Schober, MLT (ASCP), James Rolke, George Tidmarsh, MD PhD, Michael Andreeff, MD PhD, Peter P. Ruvolo, PhD

Blood (2014) 124 (21): 904.

https://doi.org/10.1182/blood.V124.21.904.904

Published: 2014

Journal Articles

The B-Cell Receptor Is Required for Optimal Viability, Growth, and Chemotherapy Resistance of Diffuse Large B-Cell Lymphoma Cell Lines of the Germinal Center B-Cell Subtype

Ondrej Havranek, MDPhD, Stefan Koehrer, MD, Justin M Comer, Zhiqiang Wang, PhD, Jingda Xu, PhD, Dipanjan Ghosh, PhD, Nicholas Shinners, PhD, Luhong Sun, MD PhD, Wencai Ma, PhD, Jan A Burger, MDPhD, R Eric Davis, MD

Blood (2014) 124 (21): 493.

https://doi.org/10.1182/blood.V124.21.493.493

Published: 2014

Journal Articles

AML Genotype-Specific and Non-Specific Regulation of Mesenchymal Stromal Cell Transcriptome in the Bone Marrow Microenvironment

Rodrigo Jacamo, PhD, Xiaoyang Ling, PhD, Zhiqiang Wang, Wencai Ma, PhD, Min Zhang, PhD, Peter P. Ruvolo, PhD, Vivian R Ruvolo, MA, Scott W. Lowe, PhD, Johannes Zuber, MD, Marina Konopleva, MD PhD, R Eric Davis, MD, Michael Andreeff, MD PhD

Blood (2014) 124 (21): 1586.

https://doi.org/10.1182/blood.V124.21.1586.1586

Published: 2014

Journal Articles

Studies of the Proteasome Inhibitor Sensitivity Modulator Tight Junction Protein 1 Highlight a Role for Signaling through the Epidermal Growth Factor Receptor in Determining Proteasome Capacity

Blood (2014) 124 (21): 3414.

https://doi.org/10.1182/blood.V124.21.3414.3414

Published: 2014

Journal Articles

Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-κB mediates chemoresistance

Blood (2014) 123 (17): 2691–2702.

https://doi.org/10.1182/blood-2013-06-511527

Published: 2014

Includes: Supplemental data

Journal Articles

Bone Marrow Microenvironment Induces Stem Cell-Like Phenotype In Acute Myeloid Leukemia

Venkata L Battula, Ph.D., Juliana M Benito, PhD, Anitha Somanchi, Seshagiri Duvvuri, Lauren Hodgson, Ye Chen, PhD, Wencai Ma, Ph.D., Richard E. Davis, M.D., Ian K. McNiece, PhD, Elizabeth J Shpall, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD

Blood (2013) 122 (21): 2457.

https://doi.org/10.1182/blood.V122.21.2457.2457

Published: 2013

Journal Articles

Proteomic, Gene Expression, and Micro-RNA Analysis Of Bone Marrow Mesenchymal Stromal Cells In Acute Myeloid Leukemia Identifies Pro-Inflammatory, Pro-Survival Signatures In Vitro and In Vivo

Blood (2013) 122 (21): 3685.

https://doi.org/10.1182/blood.V122.21.3685.3685

Published: 2013

Journal Articles

Connective tissue growth factor regulates adipocyte differentiation of mesenchymal stromal cells and facilitates leukemia bone marrow engraftment

V. Lokesh Battula, Ye Chen, Maria da Graca Cabreira, Vivian Ruvolo, Zhiqiang Wang, Wencai Ma, Sergej Konoplev, Elizabeth Shpall, Karen Lyons, Dirk Strunk, Carlos Bueso-Ramos, Richard Eric Davis, Marina Konopleva, Michael Andreeff

Blood (2013) 122 (3): 357–366.

https://doi.org/10.1182/blood-2012-06-437988

Published: 2013

Includes: Supplemental data

Journal Articles

NF-κB Activation in Mesenchymal Stromal Cells Mediates Leukemia Cell Chemoresistance

Rodrigo Jacamo, Ph.D, Ye Chen, PhD, Zhiqiang Wang, Ph.D., Wencai Ma, Ph.D., Min Zhang, Ph.D., Venkata L Battula, Ph.D., Wendy D. Schober, MLT (ASCP), Richard E Davis, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD

Blood (2012) 120 (21): 3518.

https://doi.org/10.1182/blood.V120.21.3518.3518

Published: 2012

Journal Articles

Targeting the insulin-like growth factor-1 receptor to overcome bortezomib resistance in preclinical models of multiple myeloma

Deborah J. Kuhn, Zuzana Berkova, Richard J. Jones, Richard Woessner, Chad C. Bjorklund, Wencai Ma, R. Eric Davis, Pei Lin, Hua Wang, Timothy L. Madden, Caimiao Wei, Veerabhadran Baladandayuthapani, Michael Wang, Sheeba K. Thomas, Jatin J. Shah, Donna M. Weber, Robert Z. Orlowski

Blood (2012) 120 (16): 3260–3270.

https://doi.org/10.1182/blood-2011-10-386789

Published: 2012

Includes: Supplemental data

NARROW

Targeting Wnt/β-Catenin and BCL-2, Two Critical Survival Factors, Synergistically Induces Apoptosis in AML Via Rac1-Mediated MCL-1 Inhibition

Mutational landscape of myelodysplastic/myeloproliferative neoplasm–unclassifiable

C-Reactive Protein Promotes Bone Destruction in Human Myeloma By Stimulating Myeloma Cell Production of Osteolytic Cytokines Via the CD32/FcγRII-p38MAPK-Twist Axis

Tonic B-cell receptor signaling in diffuse large B-cell lymphoma

Effects of CCL2/CCR2 Blockade in Acute Myeloid Leukemia

ONC201 Induces p53-Independent Apoptosis and Abrogates Stem Cell Function in Hematological Malignancies By Induction of ATF4 through Integrated Stress Response

Gene Expression Profiling for Molecular Features of Response in a Phase I Trial of Alisertib Plus Romidepsin for Relapsed/Refractory Aggressive B- and T-Cell Lymphomas

B-Cell Receptor Signaling in Diffuse Large B-Cell Lymphoma: Tonic Alone in the Germinal Center B-Cell Subtype, Plus Self Antigen-Induced in the Activated B-Cell Subtype

Antileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy

Mucin 20 (MUC20) Modulates Proteasome Assembly Chaperones through the c-MET Pathway and Is a Biomarker of Proteasome Inhibitor Sensitivity in Myeloma

GCS-100 Induces Apoptosis of Acute Myeloid Leukemia Cells By Disrupting Galectin-Mediated Survival Signaling

The B-Cell Receptor Is Required for Optimal Viability, Growth, and Chemotherapy Resistance of Diffuse Large B-Cell Lymphoma Cell Lines of the Germinal Center B-Cell Subtype

AML Genotype-Specific and Non-Specific Regulation of Mesenchymal Stromal Cell Transcriptome in the Bone Marrow Microenvironment

Studies of the Proteasome Inhibitor Sensitivity Modulator Tight Junction Protein 1 Highlight a Role for Signaling through the Epidermal Growth Factor Receptor in Determining Proteasome Capacity

Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-κB mediates chemoresistance

Bone Marrow Microenvironment Induces Stem Cell-Like Phenotype In Acute Myeloid Leukemia

Proteomic, Gene Expression, and Micro-RNA Analysis Of Bone Marrow Mesenchymal Stromal Cells In Acute Myeloid Leukemia Identifies Pro-Inflammatory, Pro-Survival Signatures In Vitro and In Vivo

Connective tissue growth factor regulates adipocyte differentiation of mesenchymal stromal cells and facilitates leukemia bone marrow engraftment

NF-κB Activation in Mesenchymal Stromal Cells Mediates Leukemia Cell Chemoresistance

Targeting the insulin-like growth factor-1 receptor to overcome bortezomib resistance in preclinical models of multiple myeloma

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American Society of Hematology

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American Society of Hematology

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